• Biomedical Science Letters
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• v.15 no.4
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• pp.327-333
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• 2009

Heterotrimeric GTP binding proteins, G-proteins, mediate signal transduction generated by neurotransmitters and hormones. Among G-proteins, Go proteins are the most abundant in brain and classified as a member of Gi family. Ras-like protein in all tissues (Rit), one of the small GTPases, is a member of a Ras superfamily and identified as an important regulator of neuronal differentiation and cell transformation. Recently, we have reported that Rit functioned as a candidate downstream effector for alpha subunit of Go proteins ($Go{\alpha}$) and regulated neurite outgrowth triggered by $Go{\alpha}$ activation. In this study, we showed that the GTPase domain of $Go{\alpha}$ contributed to the direct interaction with Rit. We also demonstrated that $Go{\alpha}$ could lead to an increase of Rit activity suggesting that Rit play a role as a downstream effector of $Go{\alpha}$.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.24 no.2
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• pp.65-70
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• 2024

In recent years, research on smart factory wireless mobile communication technology that wirelessly remotely controls utilities is being actively conducted. The Wi-SUN (Wireless Smart Utility Network) Alliance proposed a Wi-SUN protocol structure suitable for building a platform such as a smart factory as a new wireless communication standardization standard based on EEE802.15.4g/e. It analyzes the performance of the IEEE802.15.4e Receiver Initiated Transmission(RIT) Mode Media Access Control (MAC) in terms of throughput and latency, and looks at considerations for efficient operation. RIT mode shows that as the check interval becomes longer, delay time and throughput decrease. It was shown that as the traffic load increases, if the RIT check interval is shortened, the delay time can be shortened and throughput can be increased. RIT mode has the advantage of low power consumption and has neutral characteristics between IEEE802.15.4 and CSL mode in terms of delay time and throughput.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.6
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• pp.572-576
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• 2009

Purpose: Helicobacter (H) pylori infection has been considered the most important cause of gastritis, dyspepsia, and gastroduodenal ulcer. Radioiodine can be accumulated in the remaining thyroid tissue, salivary gland, and stomach. We investigated if the high radiation induced by radioiodine in the stomach after high dose radioiodine therapy (HD-RIT) is effective in the eradication of H. pylori infection. Materials and Methods: One hundred ninety nine patients (M:F=33:166, age $46.7{\pm}12.3$ years) who had HD-RIT (dose $159.1{\pm}25.9\;mCi$, range 120-250 mCi) after thyroidectomy due to well differentiated thyroid cancer were enrolled. To detect H. pylori infection, the urea breath tests (UBT) were performed at 1 hour before HD-RIT and at 4 weeks after HD-RIT. The results of UBT were classified as positive (${\geq}50\;dpm$) or negative (<50 dpm), and analyzed its values. Results: Of 199 patients, 103 (51.8%) patients had positive UBT before HD-RIT. Of these, 80 patients had follow-up UBT after HD-RIT. Among them, 76 (95.0%) patients had persistent positive UBT and only 4 (5.0%) patients were changed negative UBT. Among 76 patients with persistent positive UBT, 26 (34.2%) patients had increased the values of follow-up UBT, 49 (64.5%) had decreased them, and 1 (1.3%) had shown the same value. The different values of UBT between before and after HD-RIT were $62{\pm}66.1\;dpm$ in increased one of follow-up UBT, and $153.3{\pm}157.1\;dpm$ in decreased one of follow-up UBT. Conclusion: We conclude that the radiation induced by HD-RIT is ineffective in the eradication of H. pylori infection. However, it could be influential the degree or distribution of H. pylori infection.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.23 no.4
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• pp.23-28
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• 2023

In a wireless smart utility network communication system, an asynchronous low power MAC is standardized and used according to IEEE 802.15.4e. An asynchronous MAC called RIT (Receiver Initiated Transmission) has a characteristic in which delay time and power consumption are greatly affected by a check-in interval (RIT period). By waking up from sleep every check-in interval and checking whether there is data to be received, power consumption in the receiving end can be drastically reduced, but power consumption in the transmitting end occurs due to an excessive wakeup sequence. If an excessive wake-up sequence is reduced by shortening the check interval, power consumption of the receiving end increases due to too frequent wake-up. In the RIT asynchronous MAC technique, power consumption performance according to traffic load and operation of check-in interval is analyzed and applied to Wi-SUN construction.

• Korean Journal of Pharmacognosy
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• v.40 no.4
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• pp.280-285
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• 2009

Korean folk medicine 'JoRitDae' has been used mainly to cure vomiting and cancer. With regard to the botanical origin of 'JoRitDae', it has been considered to designate the rhizome of Sasa species (Gramineae), but there was no pharmacognostical confirmation on it. To clarify the botanical origin of 'JoRitDae', the anatomical characteristics of the rhizome of Sasa species growing wild in Korea and Japan, Sasa borealis, S, kurilensis, S. quelpaertensis, S. charatacea and S. senanensis were studied. As a result, it was found the morphological criteria for the five Sasa species that could discriminate them by the number of cell layers in cortex, the ratio of thickness of cortex to rhizome radius, the number of cell layers in the vascular bundle sheath, the total number of vascular bundle and thickness of vascular bundle sheath. According to these criteria, it was clarified that the commercial folk medicine 'JoRitDae' was the rhizome of Sasa borealis.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• v.61 no.12
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• pp.637-643
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• 2018

Radioimmunotherapy (RIT) is a therapy that takes advantage of the "cross-fire" effect of emitted radiation by radionuclides conjugated to tumor-directed monoclonal antibodies (mAb) (including those fragments) or peptides. While RIT has been successfully employed for the treatment of lymphoma, mostly with radiolabeled antibodies against CD20 [$^{90}yttrium$ ($^{90}Y$)-ibritumomab tiuxetan; $Zevalin^{(R)}$ and $^{131}iodine$ ($^{131}I)-tositumomab$; $Bexxar^{(R)}$], its use in solid tumors is more challenging, so far. Immuno-PET, a tool for tracking and quantification of mAbs with PET in vivo, is an exciting novel option to improve diagnostic imaging and guide mAb-based therapy. RIT in solid tumors including head and neck cancer may be an alternative treatment with advances in various biological, chemical, and treatment procedures, and it may help to reduce unnecessary exposure and enhance the therapeutic efficacy. Also, immuno-PET based on RIT might play an important role in cancer staging, in patients or targets selection of targeted therapeutics and in monitoring the response of targeted therapeutics as precision medicine. In this review, fundamentals of RIT/immune-PET and current knowledge of the preclinical/clinical trials in RIT for solid tumor including head and neck cancer are reviewed.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.27 no.2
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• pp.95-101
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• 2016

Background and Objectives : The main purpose of this study is to clarify perceptual and acoustic analysis for the patients with hypothyroidism after thyroidectomy especially focused on the characteristics of speech articulation with special reference to the consonant production. Materials and Methods : The subjects of the research were 40 male and female adults (males : 5, females : 35). They were all received radioactive iodine treatment which after total thyroidectomy. Voice samples were collected during the three stages of after surgery, pre-radioisotope treatment (RIT), and post-RIT. The acoustic analysis was conducted by using Pratt (ver.5.2.21) after measuring voice onset time (VOT). The subjective evaluation of the voices used CAPE-V. Results : A significant decrease in overall severity was displayed in the CAPE-V following RIT. It may be conjectured that this is connected to the change in voice following RIT. The loudness of the sound displayed a significant decrease in the CAPE-V following RIT. It is conjectured that this is connected to the decrease in vocal intensity following RIT. No statistically significant results were revealed for the comparative analysis on the voice onset time (VOT) in all plosives during the three periods. Conclusion : Perceptually, the overall severity of the voice with hypothyroidism was changed significantly before and after RIT. Eventhough VOT were not significantly changed, it tended to decrease VOT in patients with hypothyroidism.

• Atmosphere
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• v.33 no.4
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• pp.343-354
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• 2023

Turbulence produced on roadways is one of the major factors determining the dilution rates at the initial stage of traffic emissions of air pollutants and, thus, the distribution of air pollutants near the roadways. Field experiments were conducted on Gyeongbu Highway, one of the busiest highways in Korea, for 4~7 days in winter, spring, and summer. Two three-dimensional ultrasonic anemometers were installed on both sides of the highway to estimate turbulence intensities (vertical wind fluctuation and kinetic turbulence energy) induced by the roadway. Roadway-induced turbulence consists of three components: structural road-induced turbulence (S-RIT), thermal road-induced turbulence (T-RIT), and vehicle-induced turbulence (VIT). The contribution of T-RIT to the total RIT was insignificant (less than 10%), and the majority of RIT was S-RIT (by the highway embankment) and VIT. In this study, we propose the empirical relationships of VIT as a function of traffic density and wind speed under free-flow traffic conditions. Although this empirical relationship appears to underestimate the VIT, it can be applied to the air quality models easily because the relationship is simple and only needs readily obtainable input variables (wind speed and traffic information).

• Bulletin of the Society of Naval Architects of Korea
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• v.22 no.2
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• pp.49-65
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• 1985

The RIT(Research Institude of Technology) in KTMI(Korea Tacoma Marine Industries, Ltd) has played a vital role in maintaining the comapany's leader ship as a pioneer in the technical development of shipbuilding and new type of special vessel design. As a results, in February of 1981, the RIT could succeed in designing and constructing a small manned test hovercraft. In Arpril of 1983, the RIT started to design a 12M class, 55knots hovercraft with the highly skilled and experienced technology through the development of 4 kinds of SES(Surface Effect Ship), totally 10 vessels. In December of 1984, the diesel-powered 12M class hovercraft of proto type was developed with RIT'S own technical ability. The craft is the first hovercraft in domestic and the first diesel-powered hovercraft in Asia area. The paper describe the progress of development and general review of technology and concept of design about the hovercraft developed.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.28-31
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• 2004

This paper describe analysis active microstrip antenna with low noise amplifier at 900 MHz for mobile communication. The microstrip patch antenna is integrated with low noise amplifier on a permittivity 4.5 (Epoxy-FR4) and thickness of substrate 1.6 mm. Low noise amplifier is designed by using GaAs FETs. The analysis characteristics of antenna include return loss, input impedance, vswr, radiation pattarn, bandwidth and gain of antenna. Mesurement gain of antenna is shown 19.2435 dBi.