• Korean Journal of Radiology
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• v.22 no.9
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• pp.1514-1524
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• 2021

Objective: To develop a radiomics risk score based on dynamic contrast-enhanced (DCE) MRI for prognosis prediction in patients with glioblastoma. Materials and Methods: One hundred and fifty patients (92 male [61.3%]; mean age ± standard deviation, 60.5 ± 13.5 years) with glioblastoma who underwent preoperative MRI were enrolled in the study. Six hundred and forty-two radiomic features were extracted from volume transfer constant (K^trans), fractional volume of vascular plasma space (V_p), and fractional volume of extravascular extracellular space (V_e) maps of DCE MRI, wherein the regions of interest were based on both T1-weighted contrast-enhancing areas and non-enhancing T2 hyperintense areas. Using feature selection algorithms, salient radiomic features were selected from the 642 features. Next, a radiomics risk score was developed using a weighted combination of the selected features in the discovery set (n = 105); the risk score was validated in the validation set (n = 45) by investigating the difference in prognosis between the "radiomics risk score" groups. Finally, multivariable Cox regression analysis for progression-free survival was performed using the radiomics risk score and clinical variables as covariates. Results: 16 radiomic features obtained from non-enhancing T2 hyperintense areas were selected among the 642 features identified. The radiomics risk score was used to stratify high- and low-risk groups in both the discovery and validation sets (both p < 0.001 by the log-rank test). The radiomics risk score and presence of isocitrate dehydrogenase (IDH) mutation showed independent associations with progression-free survival in opposite directions (hazard ratio, 3.56; p = 0.004 and hazard ratio, 0.34; p = 0.022, respectively). Conclusion: We developed and validated the "radiomics risk score" from the features of DCE MRI based on non-enhancing T2 hyperintense areas for risk stratification of patients with glioblastoma. It was associated with progression-free survival independently of IDH mutation status.

• Journal of Navigation and Port Research
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• v.39 no.6
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• pp.485-491
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• 2015

The technology review about risk of hypothermia of victim according to heat transfer characteristic of life raft and sea state can use accident correspondence of standing and sinking of ship. This study studied heat transfer characteristics required for the design of life raft and thermal insulation property analysis and evaluation methods. In addition, it is study for comprehend the risk of hypothermia and suggest analysis result that is experiment of thermal insulation property and body temperature property for decide of prediction the body temperature decline Thermal Analysis apply the finite element analysis method is comprehended the property of heat conductivity, convective effect of sea water and properties changes according to property of insulation material. it measure the heat flux with attach temperature sensor on body in order to comprehend the variation of body temperature with boarding a life raft experiment on a human body. This study validate results by comparing variation of temperature measured from experiment on a body with variation of temperature from finite element analysis model. Also, the criteria of hypothermia was discussed through result of finite element analysis.

• Korean Journal of Construction Engineering and Management
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• v.11 no.3
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• pp.134-144
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• 2010

In China, the enhancement of water services has become the most crucial issue confronted with the rapid urbanization and industrialization process. A huge financial gap to meet the demand for water infrastructure and need for adopting advanced operation technology precipitated the rapid growth of PPP over the last 10 years. Diverse schemes of PPP such as TOT, Divestiture, and Management Contract and Lease have been practiced. Local governments and private investors/operator have adjusted their objectives and strategies to avoid potential pitfalls behind BOT projects in China. However, current academic research outcomes do not properly reflect important issues of BOT projects or related case studies in China. This limitation has brought in the lack of assessment of important risks and success factors required for the improvement of the body of risk management. In this regard, this study uses the market analysis method to identify major schemes of PPP water projects and conducts case studies on five PPP projects to identify key risk and success factors in association with each different scheme. It is expected that the risk and success factors identified from the cases will be used as reference to Korean companies which plan to enter the Chinese water market.

• Clinical and Experimental Reproductive Medicine
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• v.43 no.3
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• pp.164-168
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• 2016

Objective: Assisted reproductive technology has been associated with an increase in multiple pregnancies. The most effective strategy for reducing multiple pregnancies is single embryo transfer. Beginning in October 2015, the National Supporting Program for Infertility in South Korea has limited the number of embryos that can be transferred per in vitro fertilization (IVF) cycle depending on the patient's age. However, little is known regarding the effect of age and number of transferred embryos on the clinical outcomes of Korean patients. Thus, this study was performed to evaluate the effect of the number of transferred blastocysts on clinical outcomes. Methods: This study was carried out in the Fertility Center of CHA Gangnam Medical Center from January 2013 to December 2014. The clinical outcomes of 514 women who underwent the transfer of one or two blastocysts on day 5 after IVF and of 721 women who underwent the transfer of one or two vitrified-warmed blastocysts were analyzed retrospectively. Results: For both fresh and vitrified-warmed cycles, the clinical pregnancy rate and live birth or ongoing pregnancy rate were not significantly different between patients who underwent elective single blastocyst transfer (eSBT) and patients who underwent double blastocyst transfer (DBT), regardless of age. However, the multiple pregnancy rate was significantly lower in the eSBT group than in the DBT group. Conclusion: The clinical outcomes of eSBT and DBT were equivalent, but eSBT had a lower risk of multiple pregnancy and is, therefore, the best option.

• Journal of the Korean Geotechnical Society
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• v.22 no.6
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• pp.51-61
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• 2006

An efficient and accurate hybrid reliability analysis method is proposed in this paper to quantify the risk of an axially loaded single pile considering pile-soil interaction behavior and uncertainties in various design variables. The proposed method intelligently integrates the concepts of the response surface method, the finite difference method, the first-order reliability method, and the iterative linear interpolation scheme. The load transfer method is incorporated into the finite difference method for the deterministic analysis of a single pile-soil system. The uncertainties associated with load conditions, material and section properties of a pile and soil properties are explicitly considered. The risk corresponding to both serviceability limit state and strength limit state of the pile and soil is estimated. Applicability, accuracy and efficiency of the proposed method in the safety assessment of a realistic pile-soil system subjected to axial loads are verified by comparing it with the results of the Monte Carlo simulation technique.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2006.11a
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• pp.278-283
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• 2006

Koran Government introduced BTL(Build-Transfer-Lease) to provide convenience through early supplying infrastructure and plans to invest 8,315million dollar to 84 projects of 15 BTL type involving official residence and railroad. But some of construction company hates to invest BTL projects because of its low earning rate. In addition if we correctively apply project which partly has profitability to BTL, the earnning rate declines more seriously. So this paper presents BTL+BTO model which operates BTL in the non-profitable parts to improve convenience of users and BTO in the profitable parts to improve earning rate. BTL+BTO model based on operate period was presented and its suitability was confirmed by applting 00 region official residence project.

• Progress in Superconductivity and Cryogenics
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• v.17 no.1
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• pp.10-13
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• 2015

High-temperature superconducting coated conductors (HTS-CCs) are good candidates for resistive superconducting fault current limiter (RSFCL) applications. However, the high current density they can carry and their low thermal diffusivity expose them to the risk of thermal instability. In order to find the best compromise between stability and cost, it is important to study the heat transfer between HTS-CCs and the liquid nitrogen ($LN_2$) bath. This paper presents an experimental method to monitor in real-time the temperature of a quenched HTS-CC during a current pulse. The current and the associated voltage are measured, giving a precise knowledge of the amount of energy dissipated in the tape. These values are compared with an adiabatic numerical thermal model which takes into account heat capacity temperature dependence of the stabilizer and substrate. The result is a precise estimation of the heat transfer to the liquid nitrogen bath at each time step. Measurements were taken on a bare tape and have been repeated using increasing $Kapton^{(R)}$ insulation layers. The different heat exchange regimes can be clearly identified. This experimental method enables us to characterize the recooling process after a quench. Finally, suggestions are done to reduce the temperature increase of the tape, at a rated current and given limitation time, using different thermal insulation thicknesses.

• Journal of Environmental Health Sciences
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• v.47 no.2
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• pp.144-154
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• 2021

Objectives: This study was intended to identify hazard contribution by region, media, and chemical by calculating a hazard-based index using pollutant release and transfer register (PRTR) data. Methods: PRTR data for the period 2011 to 2016 was analyzed to examine the regional trends in toxic releases in terms of quantity and to create a corresponding hazard-based index. For the hazard-based index, the Risk-Screening Environmental Indicators (RSEI) Model was used. Results: The results of the trend analysis show that total releases decreased slightly, but health hazard levels increased consistently. According to the outcome of regional contribution analysis of the hazard-based index, Chungcheongnam-do, Jeollabuk-do and Gyeonggi-do Provinces showed a high ratio in the index for air and water release pollutants, while Gyeongsangbuk-do and Gyeongsangnam-do Provinces showed a high ratio in the index of soil release and waste transfer pollutants. Also, as a result of the analysis of the top ranked substances in the hazard-based index, it was found that chromium, cobalt and its compounds, and ethylene oxide contributed greatly to air release substances, while chromium, benzene, and lead and its compounds contributed greatly to water release substances. Conclusion: These results showed considerable disparities between total release and health hazard levels, especially in the analysis of contribution by regions and by chemical substance. Therefore, the hazard-based index should be used both to support a more comprehensive and robust approach to screening of chemicals for environmental health policy and for management.

• Korean Chemical Engineering Research
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• v.57 no.3
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• pp.351-357
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• 2019

This research was performed to propose domestic standard for design and management of flexible hose by analyzing chlorine leak caused by breakage of the hose in Ulsan, 2018. The leak had multiple causes but this paper focuses on analyzing the cause of breakage of flexible hose, the direct cause. According to the analysis, flexible hose that the company of the accident used for chlorine transfer was inappropriate in several aspects including material and wall thickness. And even pressure test had been conducted below operating pressure. Upon investigation on five companies that handle chlorine in Ulsan, four companies were using inappropriate flexible hose for chlorine transfer. Since there is no domestic standard for the design of flexible hose for chlorine transfer at present, it is hard to examine its design adequacy. Design standard of flexible hose used in chlorine transfer that is applicable domestically is proposed based on this research. It will contribute to the reduction in risk of breakage of the hose if the proposed standard could be applied in design and examination of flexible hose.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.39 no.3
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• pp.399-407
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• 2019

In Korea, the construction industry has been known to have the highest risk of safety accidents compared to other industries. Therefore, in order to improve safety in the construction industry, several researches have been carried out from the past. This study aims at improving safety of labors in construction site by constructing an effective automatic safety helmet detection system using object detection algorithm based on image data of construction field. Deep learning was conducted using Region-based Fully Convolutional Network (R-FCN) which is one of the object detection algorithms based on Convolutional Neural Network (CNN) with Transfer Learning technique. Learning was conducted with 1089 images including human and safety helmet collected from ImageNet and the mean Average Precision (mAP) of the human and the safety helmet was measured as 0.86 and 0.83, respectively.