• Title/Summary/Keyword: Risk quantification

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Study on the Methodology of the Microbial Risk Assessment in Food (식품중 미생물 위해성평가 방법론 연구)

  • 이효민;최시내;윤은경;한지연;김창민;김길생
    • Journal of Food Hygiene and Safety
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    • v.14 no.4
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    • pp.319-326
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    • 1999
  • Recently, it is continuously rising to concern about the health risk being induced by microorganisms in food such as Escherichia coli O157:H7 and Listeria monocytogenes. Various organizations and regulatory agencies including U.S.FPA, U.S.DA and FAO/WHO are preparing the methodology building to apply microbial quantitative risk assessment to risk-based food safety program. Microbial risks are primarily the result of single exposure and its health impacts are immediate and serious. Therefore, the methodology of risk assessment differs from that of chemical risk assessment. Microbial quantitative risk assessment consists of tow steps; hazard identification, exposure assessment, dose-response assessment and risk characterization. Hazard identification is accomplished by observing and defining the types of adverse health effects in humans associated with exposure to foodborne agents. Epidemiological evidence which links the various disease with the particular exposure route is an important component of this identification. Exposure assessment includes the quantification of microbial exposure regarding the dynamics of microbial growth in food processing, transport, packaging and specific time-temperature conditions at various points from animal production to consumption. Dose-response assessment is the process characterizing dose-response correlation between microbial exposure and disease incidence. Unlike chemical carcinogens, the dose-response assessment for microbial pathogens has not focused on animal models for extrapolation to humans. Risk characterization links the exposure assessment and dose-response assessment and involve uncertainty analysis. The methodology of microbial dose-response assessment is classified as nonthreshold and thresh-old approach. The nonthreshold model have assumption that one organism is capable of producing an infection if it arrives at an appropriate site and organism have independence. Recently, the Exponential, Beta-poission, Gompertz, and Gamma-weibull models are using as nonthreshold model. The Log-normal and Log-logistic models are using as threshold model. The threshold has the assumption that a toxicant is produce by interaction of organisms. In this study, it was reviewed detailed process including risk value using model parameter and microbial exposure dose. Also this study suggested model application methodology in field of exposure assessment using assumed food microbial data(NaCl, water activity, temperature, pH, etc.) and the commercially used Food MicroModel. We recognized that human volunteer data to the healthy man are preferred rather than epidemiological data fur obtaining exact dose-response data. But, the foreign agencies are studying the characterization of correlation between human and animal. For the comparison of differences to the population sensitivity: it must be executed domestic study such as the establishment of dose-response data to the Korean volunteer by each microbial and microbial exposure assessment in food.

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Revision of the Railway Human Reliability Analysis Procedure and Development of an R-HRA Software (철도사고 위험도평가를 위한 철도 인간신뢰도분석 방법의 개정과 전산 소프트웨어의 개발)

  • Kim, Jae-Whan;Kim, Seung-Hwan;Jang, Seung-Cheol
    • Journal of the Korean Society for Railway
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    • v.11 no.4
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    • pp.404-409
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    • 2008
  • This paper consists largely of two parts: the first part introduces the revised railway human reliability analysis (R-HRA) method which is to be used under the railway risk assessment framework, and the second part presents the features of a computer software which was developed for aiding the R-HRA process. The revised R-HRA method supplements the original R-HRA method by providing a specific task analysis guideline and a classification of performance shaping factors (PSFs) to support a consistent analysis between analysts. The R-HRA software aids the analysts in gathering information for HRA, qualitative error prediction including identification of external error modes and internal error modes, quantification of human error probability, and reporting the overall analysis results. The revised R-HRA method and software are expected to support the analysts in an effective and efficient way in analysing human error potential in railway event or accident scenarios.

Assessment of Soil Erosion Loss by Using RUSLE and GIS in the Bagmati Basin of Nepal

  • Bastola, Shiksha;Seong, Yeon Jeong;Lee, Sang Hyup;Shin, Yongchul;Jung, Younghun
    • Journal of the Korean GEO-environmental Society
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    • v.20 no.3
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    • pp.5-14
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    • 2019
  • This study attempted to study the soil erosion dynamic in the Bagmati Basin of Nepal. In this study, an inclusive methodology that combines Revised Universal Soil Loss Equation (RUSLE) and GIS techniques was adopted to determine the distribution of soil loss in the study basin. As well, this study attempts to study the intensity of soil erosion in the seven different land use patterns in the Bagmati Basin. Soil loss is an associated phenomenon of hydrologic cycle and this dynamic phenomenon possesses threats to sustainability of basin hydrology, agriculture system, hydraulic structures in operation and overall ecosystem in a long run. Soil conservation works, and various planning and design of watersheds works demands quantification of soil loss. The results of the study in Bagmati Basin shows the total annual soil loss in the basin is 22.93 million tons with an average rate of 75.83T/ha/yr. The computed soil loss risk was divided into five classes from tolerable to severe and the spatial pattern was mapped for easy interpretation. Also, evaluation of soil loss in different land use categories shows barren area has highest rate of soil loss followed by agriculture area. This is a preliminary work and provides erosion risk scenario in the basin. The study can be further used for strategic planning of land use and hydrologic conservation works in a basin.

Monitoring of heavy metals, bisphenol A and phenol migrated from food packages for delivery

  • Cho, Hyunnho;Yun, Ho Cheol;Lee, Ji Yoon;Kwon, Hyeon Jeong;Jeong, Eun Jung;Kim, Da Young;Lee, Seong Ju;Kang, Jung Mi
    • Analytical Science and Technology
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    • v.35 no.1
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    • pp.15-23
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    • 2022
  • Food delivery is gaining popularity due to changes in lifestyle and dietary patterns. However, packages used to delivery food may contain contaminants including heavy metals, or additives added during manufacturing process which may migrate into food during processing and transportation. In this study, a total of 58 food packages for delivery were collected and tested for migration of heavy metals (lead, cadmium and arsenic), bisphenol A and phenol into food simulants. The method was validated by evaluating linearity of calibration curve, limit of detection, limit of quantification, recovery and precision. Result of heavy metal migration showed that lead was the most frequently migrated metal and the highest concentration was detected in a polypropylene sample. Although there are no specific migration limits for bisphenol A and phenol in packaging materials tested in this study, migrations of bisphenol A and phenol were detected in some packages. This may due to contamination or additives added during manufacture of packages. Risk (%) was calculated to analyze the risk associated with the migration of heavy metals, bisphenol A and phenol, and was always below 1 %. These results showed that food packages for delivery are safe in terms of heavy metals, bisphenol A and phenol migration.

Prognostic Value of Dual-Energy CT-Based Iodine Quantification versus Conventional CT in Acute Pulmonary Embolism: A Propensity-Match Analysis

  • Dong Jin Im;Jin Hur;Kyunghwa Han;Young Joo Suh;Yoo Jin Hong;Hye-Jeong Lee;Young Jin Kim;Byoung Wook Choi
    • Korean Journal of Radiology
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    • v.21 no.9
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    • pp.1095-1103
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    • 2020
  • Objective: The present study aimed to investigate whether quantitative dual-energy computed tomography (DECT) parameters offer an incremental risk stratification benefit over the CT ventricular diameter ratio in patients with acute pulmonary embolism (PE) by using propensity score analysis. Materials and Methods: This study was conducted on 480 patients with acute PE who underwent CT pulmonary angiography (CTPA) or DECT pulmonary angiography (DE CT-PA). This propensity-matched study population included 240 patients with acute PE each in the CTPA and DECT groups. Altogether, 260 (54.1%) patients were men, and the mean age was 64.9 years (64.9 ± 13.5 years). The primary endpoint was all-cause death within 30 days. The Cox proportional hazards regression model was used to identify associations between CT parameters and outcomes and to identify potential predictors. Concordance (C) statistics were used to compare the prognoses between the two groups. Results: In both CTPA and DECT groups, right to left ventricle diameter ratio ≥ 1 was associated with an increased risk of all-cause death within 30 days (hazard ratio: 3.707, p < 0.001 and 5.573, p < 0.001, respectively). However, C-statistics showed no statistically significant difference between the CTPA and DECT groups for predicting death within 30 days (C-statistics: 0.759 vs. 0.819, p = 0.117). Conclusion: Quantitative measurement of lung perfusion defect volume by DECT had no added benefit over CT ventricular diameter ratio for predicting all-cause death within 30 days.

Impact of Climate Change on Food Safety: A Mini-review (기후변화와 식품안전에 관한 소고)

  • Kim, Jong-Gyu;Kim, Joong-Soon
    • Journal of Environmental Health Sciences
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    • v.42 no.6
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    • pp.465-477
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    • 2016
  • Objectives: This review examined the scientific evidence regarding the impact of climate change on food safety. Methods: The impact of climate change on food safety was assessed based on a survey of related publications reported in the past 20 years. The terms used for literature selection reflect three aspects: climate change; food; and food safety. Results: Climate change is expected to affect the key elements of food production - water and climate. These impact on food safety through many different pathways. Directly, food shortages according to the population grovoth result in a food security/food supply problem, These relationships are commonly understood. The indirect impacts include an increase in food-borne diseases and pathogens, increased mycotoxin production, and increased risk of pesticide residues in foods due to greater use of pesticides in response to warming and increased precipitation and the accompanying diseases in certain crops. Field studies and statistical and scenario analyses were performed to provide evidence. However, quantification of these relationships is still lacking. Conclusion: Adaptation measures at the local and community levels are essential since the pressures from weather and climate events may differ according to region and sector. It is recommended that we go beyond empirical observations of the association between climate change and food safety and develop more scientific explanations. We also need to explore alternative materials for bioenergy demands in order to improve sustainability.

A Study on the Appropriateness of Design Fire Size Determining for Performance Based Design in Korea (국내 성능설계에서 선정된 설계화재의 적정성 연구)

  • Lee, Se-Myeoung
    • Fire Science and Engineering
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    • v.28 no.4
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    • pp.50-56
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    • 2014
  • The quantification of fire size in buildings must be preceded in order to design the trial of performance based design (PBD). When design fire size is determined appropriately, the trial design will become economical and safe design against fire risk. There are many problems in determining design fire size because of lacks of fire engineering data and short history of PBD in korea. Therefore, this paper has surveyed the guideline of design fire in other countries, real experimental data for a few occupancies and the cases of design fire size determining for PBD in Korea. Also, it has proposed the guideline of design fire size for various occupancies in korea after analyzing the appropriateness of design fire size.

A Postural Classification Scheme of Upper Body for Females for Quantifying Postural Load of Working Postures (자세 부하 측정을 위한 상체에 대한 여성의 자세 분류 체계)

  • Kee, Dohyung
    • Journal of Korean Institute of Industrial Engineers
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    • v.28 no.2
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    • pp.223-231
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    • 2002
  • Recently, work-related musculoskeletal disorders(WMSDs) have rapidly increased and have been a major issue in the field of industrial safety. Of several physical risk factors for WMSDs, which include postures, vibration, repetitive work, speed or acceleration of movements, etc., awkward postures have been known as one of the major causes of WMSDs. For reducing the potential for injury as a result of postures, cost effective quantification of the magnitude for physical exposure to poor working postures is important and needed. To do this, several postural classification schemes have been developed and used in industrial sites. It is known that perceived discomfort for joint motions and muscle strength for females were much less than those for males. However, the existing postural classification schemes were developed without considering these gender effects. This study aims to develop a new postural classification scheme for female workers, based on the perceived discomfort for joint motions. The result showed that there was significant difference between the schemes for female and male. It was also found that when compared with OWAS, RULA and REBA, postural load was quantified more precisely with the developed scheme. It is recommended that different schemes according to gender of workers involved in work be used in order to accurately evaluate postural load of work postures.

A Review of Scientific Evidence on Indoor Air of School Building: Pollutants, Sources, Health Effects and Management

  • Chithra, V.S;Shiva, Nagendra S.M
    • Asian Journal of Atmospheric Environment
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    • v.12 no.2
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    • pp.87-108
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    • 2018
  • Schools are one of the critical social infrastructures in a society, the first place for social activity and the most important indoor environment for children besides the home. Poor IAQ in classrooms can increase the chance of long-term and short-term health problems for students and staffs; affects productivity of teachers; and degrade the student learning environment and comfort levels. The primary objective of this paper is to review and summarize available scientific evidence on indoor air quality of schools and related health effects in children. It was found that the indoor air pollutant levels in school buildings varied over a wide range in different parts of the world depending on site characteristics, climatic conditions, outdoor pollution levels, occupant activities, ventilation type and building practices. Among the indoor air pollutants, particulate matter concentrations were found to be very high in many schools. Outdoor pollutant sources also play a major role in affecting the IAQ of the school building. Hence, scientific knowledge on sources of indoor pollutants, quantification of emissions, temporal and spatial dispersion of pollutants, toxicological properties, chemical and morphological characteristics of the pollutants and associated health risk among children in the school buildings are essential to evaluate the adequacy and cost effectiveness of control strategies for mitigating the IAQ issues.

A Framework for measuring query privacy in Location-based Service

  • Zhang, Xuejun;Gui, Xiaolin;Tian, Feng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.5
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    • pp.1717-1732
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    • 2015
  • The widespread use of location-based services (LBSs), which allows untrusted service provider to collect large number of user request records, leads to serious privacy concerns. In response to these issues, a number of LBS privacy protection mechanisms (LPPMs) have been recently proposed. However, the evaluation of these LPPMs usually disregards the background knowledge that the adversary may possess about users' contextual information, which runs the risk of wrongly evaluating users' query privacy. In this paper, we address these issues by proposing a generic formal quantification framework,which comprehensively contemplate the various elements that influence the query privacy of users and explicitly states the knowledge that an adversary might have in the context of query privacy. Moreover, a way to model the adversary's attack on query privacy is proposed, which allows us to show the insufficiency of the existing query privacy metrics, e.g., k-anonymity. Thus we propose two new metrics: entropy anonymity and mutual information anonymity. Lastly, we run a set of experiments on datasets generated by network based generator of moving objects proposed by Thomas Brinkhoff. The results show the effectiveness and efficient of our framework to measure the LPPM.