• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.2
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• pp.183-193
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• 2013

The characteristics of dental treatment makes the dental staff frequently contact with patient directly. Also the daily use of high-handpieces, sharp instruments, and needles often causes bleeding on oral cavity. Therefore, the risk of cross transmission grows up. The pathogen from dental practice could spread on not only the practice itself but also the dental laboratory with contaminated impressions and prosthesis. Dental clinic staffs (dentists, dental hygienists and dental technicians) should recognize all the patients have a possibility of cross contamination, and try to prevent the transmission of infection by proper infection control. In this study, we review the articles about disinfection methods and chemical infection agents used for dental impressions, and try to figure out the suitable and effective infection control system of dental impressions.

• Archives of Craniofacial Surgery
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• v.15 no.2
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• pp.75-81
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• 2014

Background: The fibular free flap has been used as the standard methods of segmental mandibular reconstruction. The objective of mandibular reconstruction not only includes restored continuity of the mandible but also the recovery of optimal function. This paper emphasizes the advantage of the fibular free flap reconstruction over that of locking mandibular reconstruction plate fixation. Methods: The hospital charts of all patients (n=20) who had a mandibular reconstruction between 1994 and 2013 were retrospectively reviewed. Eight patients had plateonly fixation of the mandible, and the remaining 12 had vascularized fibular free flap reconstruction. Complications and outcomes were reviewed and compared between the 2 groups via statistical analysis. Results: Overall complication rates were significantly lower in the fibular flap group (8.3%) than in the plate fixation group (87.5%; p =0.001). Most (7/8) patients in the plate fixation group had experienced plate-related late complications, including plate fracture or exposure. In the fibular flap group, no complications were observed, except for a single case of donor-site wound dehiscence (1/12). Conclusion: The fibular free flap provides a more stable support and additional soft tissue support for the plate, thereby minimizing the risk of plate-related complications. Fibular free flap is the most reliable option for mandibular reconstruction, and we believe that the flap should be performed primarily whenever possible.

• Journal of the Korean Geotechnical Society
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• v.34 no.6
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• pp.25-36
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• 2018

Soil liquefaction is one of the types of major seismic damage. Soil liquefaction is a phenomenon that can cause enormous human and economic damages, and it must be examined before designing geotechnical structures. In this study, we proposed a practical method of developing a multi-hazard fragility surface for liquefaction of levee considering earthquake magnitude and water level. Limit state for liquefaction of levee was defined by liquefaction potential index (LPI), which is frequently used to assess the liquefaction susceptibility of soils. In order to consider the uncertainty of soil properties, Monte Carlo Simulation based probabilistic analysis was performed. Based on the analysis results, a 3D fragility surface representing the probability of failure by soil liquefaction as a function of the ground motion and water level has been established. The prepared multi-hazard fragility surface can be used to evaluate the safety of levees against liquefaction and to assess the risk in earthquake and flood prone areas.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.263-266
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• 2017

Numerous maritime safety technologies and systems are being developed to support safe navigation at Sea. e-Navigation is a representative system for maritime safety. It is being developed to maximize the ships safety by applying most maritime safety technologies. The e-Navigation system is being developed by the International Maritime Organization (IMO) with the aim of introducing it by 2019. South Korea has already recognized the importance of maritime safety support technology and is actively introducing e-Navigation. Korean e-Navigation is being designed to provide diverse functions for maritime safety, such as providing an optimal safe route, risk analysis, and weather information. Service modules that provide e-Navigation's each function use different types of data that are difficult to configure as a single database. In this paper, we analyze the data needed for Korean e-Navigation, the data service system structure and types that can effectively support it.

• The KIPS Transactions:PartB
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• v.16B no.6
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• pp.471-478
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• 2009

The lung diseases classifying as one of the six incurable diseases in modern days are caused mostly by smoking and air pollution. Such causes the lung function damages, and results in malfunction of the exchange of carbon dioxide and oxygen in an alveolus, which the interest is augment with risk diseases of life prolongation. With this in the paper, we proposed a diagnosis method of lung diseases by applying parameters of voice analysis aiming at the getting the voice feature extraction. Firstly, we sampled the voice data from patients and normal persons in the same age and sex, and made two sample groups from them. Also, we conducted an analysis by applying the various parameters of voice analysis through the collected voice data. The relational significance between the patient and normal groups can be evaluated in terms of speech rates and intensity as a part of analized parameters. In conclusion, the patient group has shown slower speech rates and bigger intensity than the normal group. With this, we propose the method of voice feature extraction for lung diseases.

• Korean Journal of Construction Engineering and Management
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• v.8 no.3
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• pp.106-115
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• 2007

The size and length of road tunnels have been gradually expanded as industry developed. Consequently, the risk has been increased. The decision making process for ventilation system for road tunnels involves a large amount of information on economic feasibility, construction methods, and safety etc. In situation where systematically structured decision making process is unavailable, almost decisions about ventilation systems are made based on engineers' private knowledge and experiences. Procedure and criteria to choose the best optimized ventilation system among many alternatives are proposed, breaking away from the economic dependency-oriented decision making. This paper presents a Multi-Attribute Utility Theory and AHP based function with which planners can calculate overall utility of each alternative. It is anticipated that the effective use of the proposed methodology for decision making on ventilation systems ould be able to reduce the likelihood of the occurrence of potential safety risks as well as increase the overall ventilation performance.

• Genomics & Informatics
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• v.3 no.4
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• pp.154-158
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• 2005

Germ-line mutations of the BRCA1 gene confer an increased risk for breast and ovarian cancers. BRCA1 in female cells is directly related with the maintenance of the inactive X chromosome (Xi). The effect by the loss of the BRCA1 function on the X chromosome gene expression remains unclear in cancer cells. We attempted to investigate the expression pattern of the X-linked genes by performing BRCA1 knockdown via RNA interference in the MCF7 breast cancer cell line. The transcriptional and translational levels of BRCA1 were decreased over 95% in the MCF7 cells after BRCA1 knockdown. The expression patterns of one hundred ninety X-linked genes were profiled by the X chromosome-specific cDNA arrays. A total of seven percent of the X-linked genes (14/190) were aberrantly expressed by over 2-fold in the MCF7-BRCA1 knockdown cells, which contained two up-regulated genes (2/190, 1 %) and 12 down-regulated genes (12/190, 6.3%). It is interesting that 72% of the aberrantly expressed X-linked genes were located on the Xq (10/14,) region. Our data suggests that BRCA1 may not be important to maintain X chromosome inactivation in cancer because the BRCA1 knockdown did increase the expression of the only one percent of X-linked genes in the human breast cancer cells.

• Biomedical Science Letters
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• v.24 no.3
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• pp.280-284
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• 2018

The incidence of cardiovascular diseases (CVDs) is increasing rapidly in developed countries, with CVDs now representing the leading cause of morbidity and mortality. Natural products and ethnomedicines have been shown to reduce the risk of CVDs. Garlic is a medicinal plant used throughout the world for its anti-inflammatory, antioxidant, and antiplatelet activities. Chitosan is a natural polysaccharide obtained from chitin, and derivatives of chitosan have been shown to inhibit platelet aggregation and adhesion. We hypothesized that fermented preparations of these products may possess stronger antiplatelet effects than the non-fermented forms owing to the increased bioavailability of the bioactive compounds produced during fermentation. Therefore, we compared these compounds via in vitro and ex vivo platelet aggregation assays by using standard light transmission aggregometry and ex vivo granule secretions from rat platelets. We found that fermented preparations exerted more potent and significant inhibition of platelet aggregation both in vitro and ex vivo. Likewise, ATP release from dense granules of platelets was also significantly inhibited in fermented preparation-treated rat platelets compared to that in non-fermented preparation-treated ones. We concluded that fermented preparations exerted more potent effects on platelet function both in vitro and ex vivo, possibly as a result of the increased bioavailability of active compounds produced during fermentation. We therefore suggest that fermented products may be potent therapeutics against platelet-related CVDs and can be used as antiplatelet and antithrombotic agents.

• Korean Journal of Plant Resources
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• v.28 no.1
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• pp.135-144
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• 2015

The Korean daily intake of vegetable oils has increased about 2.5-fold from 17 g/day to 46 g/day for the last several decades. Perilla (Perilla frutescens var. frutescens) has been cultivated in Korea for a long time as a dietary oil seed which has the highest content of ${\alpha}$-linolenic acid, accounting for nearly 60%. It is known that the main role of ALA is as a precursor to the longer-chain ${\omega}-3$, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), the metabolic products of ${\alpha}$-linolenic acid (ALA, ${\omega}-3$). Dietary ${\omega}-3$ fatty acids reduce inflammation and the risk of chronic diseases such as heart disease, cancer, and arthritis, but they also may act as functional components for cognitive and behavioral function. Thus, ${\alpha}$-linolenic acid is one of the essential nutrients in modern dietary patterns in which much linoleic acid is consumed. Nevertheless, perilla oil, rich in ${\alpha}$-linolenic acid, can be easily oxidized, giving rise to controversies with respect to shelf life, the deterioration of the product's commercial value, and further related toxicity. Recent research using genetic modifications has tried to develop new plant oil seeds that balance the ratio of ${\omega}-6/{\omega}-3$ fatty acids. Such trials could be a strategy for improving an easily oxidizable property of perilla oil due to high ${\alpha}$-linolenic acid. Alternatively, appropriate application of antioxidant to the oil can be considerable.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.1
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• pp.1-8
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• 2010

Purpose : This study aimed to examine the relationships among five clinical measures for functional alignment of the lower extremity. Methods : Thirty healthy subjects (15 males and 15 females) were recruited for the study. The five clinical measures of functional alignment of the lower extremity included navicular drop, quadriceps angle, internal rotation of hip, and anterior and lateral pelvic tilt angles. The level of navicular drop was calculated by the difference between the height of the navicular bone in the sitting (non-weight bearing) and standing (weight bearing) positions. The quadriceps angle and internal rotation of hip were measured using a standard goniometer with photographic markers while the subjects were lying in a prone position on a table with their knee at $90^{\circ}$ flexion. Anterior and lateral pelvic tilt angles were determined using a inclinometer. Results : Correlation and a simple linear regression analysis were used to assess relationships between the clinical measures. There were significant correlations between navicular drop and quadriceps angle (p<.05), between navicular drop and internal rotation of hip (p<.05), and between quadriceps angle and internal rotation of hip (p<.01). In simple linear regression analysis, the navicular drop appeared to be a factor affecting the quadriceps angle and internal rotation of hip (p<.05). The findings suggest that navicular drop has a great impact on lower extremity alignment. Conclusion : This study might help us to examine lower extremity function and clarify its role as a potential injury risk factor.