• Journal of the Korean Society of Safety
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• v.30 no.6
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• pp.26-33
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• 2015

This study suggests systematic procedures to improve safety policies on prevention of industrial accidents associated with industrial machines and devices. Specifically, new method of cause analysis of industrial accidents associated with industrial machines and devices is suggested and the related accident data are re-analyzed. Effectiveness of direct safety regulations such as safety certification, self-declaration of conformity, safety device regulation and safety inspection of industrial machines and devices are also analyzed. Based on those analysis results, transition from the current user-oriented safety device regulation to more balanced direct regulations on both manufacturer and user is suggested. Together with severity and frequency of industrial accidents, unit severity and unit frequency need to be taken into account to further assess the risk associated with a particular industrial machine or device. Balance between safety regulations will be realized by proper adjustment of lists of safety certification and inspection, and certification and inspection standards. This will also guarantee the maximum benefit over cost in such safety regulations.

• Journal of Korean Society of Water and Wastewater
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• v.27 no.1
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• pp.121-128
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• 2013

The concern for dissolved phosphate in water/wastewater has been increasing because of the risk for eutrophication. A variety of conventional and advanced technologies were applied to meet the enforced new regulation of phosphate around the world. However, there still remained a lot of challenge because most introduced/developed method, for example, biological and physic-chemical treatment is not easy to satisfy the new regulation of phosphate in water. In order to meet the new regulation, the application of ion exchanger has been tried which showed that the removal efficiency for phosphate was strongly determined by in the presence of the competing ion, especially sulfate. As results, a new class of ion exchanger governed by ligand exchange was developed and investigated to increase the selectivity for phosphate. The current study using organic/inorganic anion exchanger developed with Lewis acid-base interaction confirms the selectivity for phosphate over sulfate. According to isotherm test and column test, the value of the maximum phosphate uptake (Q) showed 64 mg/g as $po{_4}^{3-}$ and the breakthrough for phosphate occurs after 1000 min and completely finishes at 2500 min, respectively.

• Biomolecules & Therapeutics
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• v.25 no.3
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• pp.231-238
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• 2017

Myelin is a specialized structure of the nervous system that both enhances electrical conductance and insulates neurons from external risk factors. In the central nervous system, polarized oligodendrocytes form myelin by wrapping processes in a spiral pattern around neuronal axons through myelin-related gene regulation. Since these events occur at a distance from the cell body, post-transcriptional control of gene expression has strategic advantage to fine-tune the overall regulation of protein contents in situ. Therefore, many research interests have been focused to identify RNA binding proteins and their regulatory mechanism in myelinating compartments. Fragile X mental retardation protein (FMRP) is one such RNA binding protein, regulating its target expression by translational control. Although the majority of works on FMRP have been performed in neurons, it is also found in the developing or mature glial cells including oligodendrocytes, where its function is not well understood. Here, we will review evidences suggesting abnormal translational regulation of myelin proteins with accompanying white matter problem and neurological deficits in fragile X syndrome, which can have wider mechanistic and pathological implication in many other neurological and psychiatric disorders.

• The Journal of Asian Finance, Economics and Business
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• v.6 no.1
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• pp.281-288
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• 2019

This study examines the relationship between R&D intensity and disclosure. R&D activities are essential in bringing innovation to companies. However, R&D activities are naturally uncertain and increase information asymmetry. Thus, firms with high R&D activities are more likely to have the incentive to communicate the potential of R&D investment to the market through voluntary disclosure and, concurrently, resolve information asymmetry. Meanwhile, incentives to less voluntary disclosure exist because of the proprietary cost and the risk of competitiveness loss. Furthermore, the uncertainties inherent in R&D activities caused the possible decrease in the information accuracy. For the two opposing views, this study investigates the relationship between R&D intensity and disclosure frequency using the Regulation Fair Disclosure data in Korea. Moreover, the relationship between R&D intensity and usefulness of the information disclosed is also examined. Using firm sample listed in the 2011-2016 Korea Stock Market, results show that firms with high R&D intensity make disclosures more frequent. Subsequently, the analysis using forecast sample shows that management forecast error is higher in firms with high R&D intensity. This research contributes to the existing literature by presenting evidence that R&D intensity is a significant factor affecting manager's disclosure behavior and information usefulness.

• International Journal of Computer Science & Network Security
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• v.22 no.10
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• pp.347-351
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• 2022

The article is devoted to the formation of approaches to improving the system of administration of customs payments in modern conditions. It is established that important components of the administration of customs payments are customs expertise, customs value assessment, and control over the declaration of goods to ensure the completeness and timeliness of customs duties payments to the budget. It is found that the practice of customs administration shifts the emphasis of foreign trade regulation to the use of the principles of work implying the use of the latest technologies for the preliminary electronic exchange of information, remote customs clearance of goods without the physical presence of an official, and consistent application of risk management. It is established that an important place in the structure of the state authorities regulating the foreign economic activity is given to the customs service. Furthermore, the existing problems in the implementation of international trade operations necessitate the improvement of approaches to the customs regulation of export-import activities of enterprises.

• Journal of Aerospace System Engineering
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• v.1 no.2
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• pp.13-20
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• 2007

Structural qualification plan (SQP) for aerospace vehicle is based on material certification methodology, which must be approved by certification authority. It is internationally required to use of statistically based material allowables to design aerospace vehicles with aerospace materials. In order to comply with this regulation, it is necessary to establish relatively large amount of database, which increases test costs and time. Recently NASA/FAA develop the new methodology which results in cost, time, and risk reduction, and satisfies the regulation at the same time. This paper summarizes the certification methodology of materials system as a part of structural qualification plan (SQP) of aerospace vehicles and also thermal management of the vehicle system, like thermal protection materials system and thermally conductive material system. Materials design allowable was determined using this method for a carbon/epoxy composite material.

• Proceedings of the KAIS Fall Conference
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• 2010.11b
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• pp.859-861
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• 2010

The construction companies are facing potential EHS(Environment, Health & Safety) of major accidents to cause casualties or a financial loss and increasing social responsibility. So, they have to voluntarily accomplish the EHS management system rather than passively with regard to EHS regulation. In this study, the integrated EHS management system is developed based on cloud computing, and construction companies are to materialize self-regulation EHS process of construction workplace and to standardize the total EHS business process using the developed system. The proposed system also provides risk analysis, education/control and continuous improvement for EHS tasks and users can easily access the system on the web at a low price through cloud computing service. Eventually, the integrated system contributes to the managerial improvement by minimizing economic and physical loss caused by construction accidents.

• Journal of the Korea Safety Management & Science
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• v.12 no.4
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• pp.139-143
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• 2010

The small and medium construction companies are facing potential EHS(Environment, Health & Safety) of major accidents to cause casualties or a financial loss and increasing social responsibility. So, they have to voluntarily accomplish the EHS management system rather than passively with regard to EHS regulation. In this study, the framework of integrated EHS management system is developed based on cloud computing, and construction companies are to materialize self-regulation EHS process of construction workplace and to standardize the total EHS business process using the developed system. The proposed system also provides risk analysis, education/control and continuous improvement for EHS tasks and users can easily access the system on the web at a low price through cloud computing service. Eventually, the integrated system contributes to the managerial improvement by minimizing economic and physical loss caused by construction accidents.

• Journal of Auto-vehicle Safety Association
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• v.6 no.1
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• pp.41-47
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• 2014

A new dummy has improved biofidelity from Fair to Good compare with EuroSID2re which is currently used for regulation tests and NCAP tests. Some instrumentation of each body region has been changed to measure the assessment of injury risk. The objective of this study is to find out the injury characteristic of each dummy and to calculate the relation between external force and injury for each dummy with pendulum tests. Finally, this study suggests the optimized external force to meet consumer tests. A new dummy named WorldSID for side impact will be introduced into EuroNCAP tests after 2015. Korea government is also planning to adopt WorldSID at KNCAP tests from 2017 and Global Technical Regulation (GTR) will also adopt WorldSID to oblique side pole crash.

• International Journal of Quality Innovation
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• v.6 no.1
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• pp.58-73
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• 2005

The objective of this study is to evaluate the equipment risk before and after SEMI S2-93A implementation, thus providing a guideline for safety improvement. Semiconductor Plant A located in Taiwan's Hsinchu Science Based Industrial Park with 147 manufacturing machines was used for risk assessment. This study was carried out in three steps. First, a preliminary hazard analysis was conducted. A detailed process safety evaluation was conducted (Hazard and Operability Study, HAZOP); and finally, the equipment risk comparison before and after Semiconductor Equipment Manufacturing Instruction (SEMI S2-93A) implementation. The preliminary hazard analysis results showed high risk in 21.77% of the manufacturing machines under risk assessment at Plant A. The largest percentage existed in the Diffusion Department. The machine types specified by the hazardous work site review and inspection according to Article 26 of Labor Inspection Regulation (the machines that use such chemicals as, $SiH_4$, HF, HCL, etc. and that are determined to be highly hazardous through preliminary hazard analysis) were added to the detailed process analysis and evaluation. In the third part of this evaluation, the machines at Plant A used for detailed process safety assessment were divided into two groups based on the manufacturing data before and after 1993. The severity, possibility, and actual accident analysis before and after SEMI S2-93A implementation were compared. The Semiconductor Equipment Manufacturing Instruction (SEMI S2-93A) implementation can reduce the severity and possibility of hazard occurrence.