• Environmental Analysis Health and Toxicology
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• 제23권4호
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• pp.257-265
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• 2008

Nanotechnology is emerging as one of the key technologies of the 21 st century and is expected to enable one to broaden the applicability across a wide range of sectors that can benefit public and improve industrial competitiveness. Already, consumer products containing nanomaterials are available in markets including coatings, computers, clothing, cosmetics, sports equipment and medical devices. Recently, Institute of Occupational Medicine in UK reported an occupational hygiene review for nanoparticles in the viewpoint of nanotoxicity. They reported that the exposure control is very important issues in workplace for exposure assessment, but no proper methods are available to measure the extent of exposures to nanoparticles in the workplace. Therefore, for the estimation of exposure of nanomaterials, we have to approach the material-balance methodology, which similarly carried out in TRI (toxic release inventory) for hazardous chemicals. In order to use this methodology, the exposure source of nanomaterials should be determined firstly. Therefore, herein we investigated the main sources and processes for the exposure to nanomaterals by conducting the survey. The results could be used to define and assess nanohazard sources.

• 한국농림기상학회지
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• 제4권3호
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• pp.133-140
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• 2002

Site-specific minimum temperature forecasts are critical in a short-term decision making procedure for preventive measures as well as a long-term strategy such as site selection in fruits industry. Nocturnal cold air pools frequently termed in mountainous areas under anticyclonic systems are very dangerous to the flowering buds in spring over Korea, but the spatial resolution to detect them exceeds the current weather forecast scale. To supplement the insufficient spatial resolution of official forecasts, we developed a GIS - assisted frost risk assesment scheme for using in mountainous areas. Daily minimum temperature data were obtained from 6 sites located in a 2.1 by 2.1 km area with complex topography near the southern edge of Sobaek mountains during radiative cooling nights in spring 2001. A digital elevation model with a 10 m spatial resolution was prepared for the entire study area and the cold air inflow was simulated for each grid cell by counting the number of surrounding cells coming into the processing cell. Primitive temperature surfaces were prepared for the corresponding dates by interpolating the Korea Meteorological Administration's automated observational data with the lapse rate correction. The cell temperature values corresponding to the 6 observation sites were extracted from the primitive temperature surface, and subtracted from the observed values to obtain the estimation error. The errors were regressed to the flow accumulation at the corresponding cells, delineating a statistically significant relationship. When we applied this relationship to the primitive temperature surfaces of frost nights during April 2002, there was a good agreement with the observations, showing a feasibility of site-specific frost warning system development in mountainous areas.

• 한국산학기술학회논문지
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• 제11권7호
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• pp.2687-2692
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• 2010

과거 홍수량 분석을 위해 다양한 연구가 진행되었으며 특히, 홍수량-지속시간-빈도곡선(flood-duration-frequency curves)의 연구가 국외에서 진행되었다. 그러나 국내의 수문자료는 하천의 특정지점에서 홍수량 자료 보다는 수위자료를 쉽게 수집 가능하기 때문에 본 연구에서는 도시유역의 홍수에 따른 홍수위험도를 정량적으로 분석하기 위하여 기존의 강우강도-지속시간-빈도곡선(Indensity-duration-frequency curves)을 응용한 홍수위-지속시간-빈도곡선(flood water level-duration-frequency curves: Fwl-D-F)방법을 제시하였다. 연구의 대상지역은 한강수계 중량천의 중량교 지점으로 18년간의 수위 자료를 이용하여 Fwl-D-F곡선을 산정하였다. 홍수위에 대한 지속기간별 빈도곡선인 Fwl-D-F 곡선은 특정한 홍수위에 따른 값을 빈도개념으로 적용이 가능하므로, 내수침수를 포함한 홍수예보에 많은 도움이 될 수 있으리라 판단된다. 또한, 특정 호우사상에 대한 강우량이 예측되면 작성된 강우강도-지속시간-빈도곡선(I-D-F곡선)과 Fwl-D-F곡선을 연계하여 임의 관측지점의 수위를 예측하는 것이 가능하다고 사료된다.

• 한국산업보건학회지
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• 제29권3호
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• pp.358-367
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• 2019

Objectives: This study aimed to review model algorithms and input parameters applied to some exposure models and to compare the simulated estimates using an exposure scenario from each model. Methods: A total of five exposure models which can estimate inhalation exposure were selected; the Korea Ministry of Environment(KMOE) exposure model, European Centre for Ecotoxicology and Toxicology of Chemicals Targeted Risk Assessment(ECETOC TRA), SprayExpo, and ConsExpo model. Algorithms and input parameters for exposure estimation were reviewed and the exposure scenario was used for comparing the modeled estimates. Results: Algorithms in each model commonly consist of the function combining physicochemical properties, use characteristics, user exposure factors, and environmental factors. The outputs including air concentration ($mg/m^3$) and inhaled dose(mg/kg/day) are estimated applying input parameters with the common factors to the algorithm. In particular, the input parameters needed to estimate are complicated among the models and models need more individual input parameters in addition to common factors. In case of CEM, it can be obtained more detailed exposure estimates separating user's breathing zone(near-field) and those at influencing zone(far-field) by two-box model. The modeled exposure estimates using the exposure scenario were similar between the models; they were ranged from 0.82 to $1.38mg/m^3$ for concentration and from 0.015 to 0.180 mg/kg/day for inhaled dose, respectively. Conclusions: Modeling technique can be used for a useful tool in the process of exposure assessment if the exposure data are scarce, but it is necessary to consider proper input parameters and exposure scenario which can affect the real exposure conditions.

• Parasites, Hosts and Diseases
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• 제57권5호
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• pp.499-504
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• 2019

Head-lice infestation, pediculosis capitis, remains a public-health burden in many countries. The widely used first-line pediculicides and alternative treatments are often too costly for use in poor socio-economic settings. Ivermectin has been considered an alternate treatment for field practice. This study was composed of 2 parts, a cross-sectional survey and an intervention study. The main objectives were to determine the prevalence and potential factors associated with head-lice infestation, and to evaluate the effectiveness and safety of oral ivermectin administration. A community-based cross-sectional survey was conducted among 890 villagers in rural areas along Thai-Myanmar border. Females with infestations were eligible for the intervention study, and 181 participated in the intervention study. A post-treatment survey was conducted to assess acceptance of ivermectin as a treatment choice. Data analysis used descriptive statistics and a generalized-estimation-equation model adjusted for cluster effect. The study revealed the prevalence of head-lice infestation was 50% among females and only 3% among males. Age stratification showed a high prevalence among females aged <20 years, and among 50% of female school-children. The prevalence was persistent among those with a history of infestation. The major risk factors were residing in a setting with other infected cases, and sharing a hair comb. The study also confirmed that ivermectin was safe and effective for field-based practice. It was considered a preferable treatment option. In conclusion, behavior-change communication should be implemented to reduce the observed high prevalence of head-lice infestation. Ivermectin may be an alternative choice for head-lice treatment, especially in remote areas.

• 대한원격탐사학회지
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• 제35권5_2호
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• pp.781-796
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• 2019

본 연구에서는 2016년 8월 태풍 "라이언록"으로 인해 극심한 피해를 입었던 회령시, 무산군 일대를 포함하고 있는 두만강 유역에 대하여 홍수특성을 분석하고자 하였다. 두만강 유역은 수문자료가 구축되어 있지 않은 미계측 유역이므로 원격탐사 자료를 통하여 유역특성 및 유출인자를 추정하여 홍수량 분석에 활용하였다. 대상유역에 대한 적용에 앞서 두만강 유역과 비교적 유역특성이 유사하고 계측자료 확보가 용이한 소양강댐 유역에 대하여 홍수유출분석을 실시함으로써 본 연구의 분석방법 및 자료의 적용성을 검증하였다. 분석결과, 태풍 "라이언록"으로 인한 홍수량은 3~5년 빈도 설계홍수량에 해당되는 것으로 향후에도 이 지역에 비슷한 수준의 홍수피해를 입을 가능성이 높음을 확인하였다. 마지막으로 본 연구를 통하여 수문관측자료가 부재한 미계측 지역에 대한 홍수량 산정시 원격탐사와 공간정보의 활용 가능성을 확인할 수 있었다.

• Safety and Health at Work
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• 제1권1호
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• pp.61-68
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• 2010

Objectives: The extent of the occupational cancer burden has rarely been estimated in Korea. The aim of this study is to provide an estimation of the population attributable fraction (PAF) of occupational cancer in Korea. Methods: Nine kinds of Group 1 carcinogens addressed by the International Agency for Research on Cancer (IARC) and 7 kinds of cancer were selected for the target carcinogens and diseases, respectively. The prevalence of carcinogen-exposed workers was estimated and correction factors were applied so that the value would be representative of the total population. Data on relative risk (RR) were taken from IARC reports and were compared with the RRs from the studies on Korean workers. The PAF was estimated according to Levin's formula. Results: The proportion of the general Korean population exposed to carcinogens was 9.7%. The PAF of total cancer was 1.1% for incident cancer cases and 1.7% for cancer deaths. The PAFs of lung cancer and leukemia were 7.0% and 4.5%, respectively. With the RRs reported from Korean studies, the PAF for lung cancer and leukemia were 3.7% and 3.4%, respectively. Conclusion: The PAF in this study (1.1%) was lower than that reported in previous studies (2-4%) from developed countries. Considering that only 9 of the 29 kinds of Group 1 carcinogens were included in this study, the PAF might be underestimated. However, because the process of industrialization in Korea differs from that which occurred in other developed countries, 1.1% of the PAF might be appropriate for Korea.

• 한국화재소방학회논문지
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• 제33권2호
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• pp.56-62
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• 2019

스프링클러는 방호구역에 설치된 감지기 또는 헤드가 화재를 감지하여 자동으로 화재를 진압하는 소화설비로 화재 초기에 뛰어난 소화효과가 있어 폭넓게 설치되고 있다. 하지만 국토교통부의 "건축물의 피난 방화구조 기준 등에 관한 규칙"에는 공장 또는 창고의 경우 스프링클러설비를 설치하면 방화구획을 3배까지 완화해 줄 수 있도록 그 근거를 제공하고 있다. 이에 본 연구에서는 스프링클러설비 설치로 방화구획을 완화한 실제 Printed Circuit Board (PCB) 공장 1개소를 대상으로 화재위험성을 분석하였고, 컴퓨터 시뮬레이션을 통한 스프링클러설비의 헤드 개방 특성 및 스프링클러 설비의 설치기준, 감열성능, 작동범위, 방수량 등을 분석하였다. 또한 이를 통해 화재 시 스프링클러 설비 작동의 문제점을 확인하고, 제도 개선을 위한 요구 살수유량 등 근거를 제시하고자 한다.

• 대기
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• 제29권1호
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• pp.1-12
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• 2019

For the allergy patient who needs to know the situation about the extent of pollen risk, the National Institute of Meteorological Sciences developed a pollen forecasting system based on the Community Multiscale Air Quality Modeling (CMAQ). In the old system, pollen emission from the oak was estimated just based on the airborne concentration and meteorology factors, resulted in high uncertainty. For improving the quality of current pollen forecasting system, therefore the estimation of pollen emission is now corrected based on the observation of pollen emission at the oak forest to better reflect the real emission pattern. In this study, the performance of the previous (NIMS2014) and current (NIMS2016) model system was compared using observed oak pollen concentration. Daily pollen concentrations and emissions were simulated in pollen season 2016 and accuracy of onset and end of pollen season were evaluated. In the NIMS2014 model, pollen season was longer than actual pollen season; The simulated pollen season started 6 days earlier and finished 13.25 days later than the actual pollen season. The NIMS2016 model, however, the simulated pollen season started only 1.83 days later, and finished 0.25 days later than the actual pollen season, showing the improvement to predict the temporal range of pollen events. Also, the NIMS2016 model shows better performance for the prediction of pollen concentration, while there is a still large uncertainty to capture the maximum pollen concentration at the target site. Continuous efforts to correct these problems will be required in the future.

• Journal of Acupuncture Research
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• 제38권2호
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• pp.96-109
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• 2021

The purpose of this study was to evaluate the effectiveness and safety of acupotomy for the treatment of patients with knee osteoarthritis. There were 9 databases searched to retrieve randomized controlled trials until August 3, 2019 regarding acupotomy versus conventional Western medicine, conventional Western medicine treatment with and without acupotomy, and Korean medicine treatment with and without acupotomy, and meta-analysis was performed. Of 303 potentially relevant studies retrieved, 43 were systematically reviewed. All studies were conducted in China. Effective rate, visual analogue scale, and Western Ontario and McMaster Universities Osteoarthritis index were used as the evaluation scales. The Ashi point was selected most frequently. In all studies, the intervention group was more effective than the control group. Meta-analysis revealed that acupotomy showed statistically significant beneficial results. Although acupotomy had a beneficial effect on knee osteoarthritis, the risk of bias of the included studies was not low. The majority of the results from the evaluation scales used were highly heterogeneous (> 50%) which reduced confidence in the estimation of effect, or had a small sample size. Further clinical research and development is required in the future.