Investigation on the Main Exposure Sources of Nanomaterials for Nanohazards Assessment

나노위해성 관리를 위한 나노물질 주요 배출원 파악

  • Kim, Young-Hun (Department of Chemical of Engineering, Kwangwoon University) ;
  • Park, Jun-Su (Department of Chemical of Engineering, Kwangwoon University) ;
  • Kim, He-Ro (Department of Chemical of Engineering, Kwangwoon University) ;
  • Lee, Jeong-Jin (School of Chemical and Biological Engineering, Seoul National University) ;
  • Bae, Eun-Joo (School of Chemical and Biological Engineering, Seoul National University) ;
  • Lee, Su-Seung (School of Chemical and Biological Engineering, Seoul National University) ;
  • Kwak, Byoung-Kyu (School of Chemical and Biological Engineering, Seoul National University) ;
  • Choi, Kyung-Hee (Environmental Exposure Assessment Division, Chemicals Assessment Department, National Institute of Environmental Research, Environmental Research Complex) ;
  • Park, Kwang-Sik (College of Pharmacy, Dongduk Women's University) ;
  • Yi, Jong-Heop (School of Chemical and Biological Engineering, Seoul National University)
  • 김영훈 (광운대학교 화학공학과) ;
  • 박준수 (광운대학교 화학공학과) ;
  • 김휘로 (광운대학교 화학공학과) ;
  • 이정진 (서울대학교 화학생물공학부) ;
  • 배은주 (서울대학교 화학생물공학부) ;
  • 이수승 (서울대학교 화학생물공학부) ;
  • 곽병규 (서울대학교 화학생물공학부) ;
  • 최경희 (국립환경과학원 환경노출평가과) ;
  • 박광식 (동덕여자대학교 약학대학) ;
  • 이종협 (서울대학교 화학생물공학부)
  • Published : 2008.12.30

Abstract

Nanotechnology is emerging as one of the key technologies of the 21 st century and is expected to enable one to broaden the applicability across a wide range of sectors that can benefit public and improve industrial competitiveness. Already, consumer products containing nanomaterials are available in markets including coatings, computers, clothing, cosmetics, sports equipment and medical devices. Recently, Institute of Occupational Medicine in UK reported an occupational hygiene review for nanoparticles in the viewpoint of nanotoxicity. They reported that the exposure control is very important issues in workplace for exposure assessment, but no proper methods are available to measure the extent of exposures to nanoparticles in the workplace. Therefore, for the estimation of exposure of nanomaterials, we have to approach the material-balance methodology, which similarly carried out in TRI (toxic release inventory) for hazardous chemicals. In order to use this methodology, the exposure source of nanomaterials should be determined firstly. Therefore, herein we investigated the main sources and processes for the exposure to nanomaterals by conducting the survey. The results could be used to define and assess nanohazard sources.

Keywords

References

  1. Borm PJA and Kreyling W. Toxicological hazards of inhaled nanoparticles-potential implications for drug delivery, J Nanosci Nanotech 2004; 4: 521-531 https://doi.org/10.1166/jnn.2004.081
  2. Kim MS, Choi K, Kim Y and Yi J. Risk assessment for health and environmental hazards of nanomaterials, Clean Technol 2007; 13: 159-170
  3. Kim Y and Yi J. Risk of nanotechnology, News & Information for Chemical Engineers 2005; 23: 338-342
  4. KISTI. Investigation results on the nano-hazard in Korea, Japan, USA, and UK, Nano Weakly 2006; 182: 2-4
  5. KISTI. Annual report on the nanotechnology 2005, 2006
  6. Lam CW, James JT, McCluskey R and Hunter RL. Pulmonary toxicity of single-wall carbon nanotubes in Mice 7 and 90 days after intratracheal instillation, Toxicol Sci 2004; 77: 126-134
  7. Malsh I and Oud M. Outcome of the open consultation on the european strategy for nanotechnogy, Nanoforum 2005
  8. Maynard A and Michelson E. Nanotechnology consumer products inventory, Woodrow Wilson International Center for Scholars 2005
  9. Morones JR, Elechiguerra JL, Camacho A, Holt K, Kouri JB, Ramirez JT and Yacaman MJ. The bactericidal effect of silver nanoparticles, Nanotechnol 2005; 16: 2346-2353 https://doi.org/10.1088/0957-4484/16/10/059
  10. NanoKorea. 2007 webpage (see http://www.nanokorea.or.kr)
  11. Oberdorster E. Manufactured nanomaterials (Fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass, Environ Health Persp 2004; 112: 1058-1062 https://doi.org/10.1289/ehp.7021
  12. Warheit DB, Brock WJ, Lee KP, Webb TR and Reed KL. Comparative pulmonary toxicity iInhalation and instillation studies with different $TiO_2$ particle formulations: Impact of surface treatments on particle toxicity, Toxicol Sci 2005; 88: 514-524 https://doi.org/10.1093/toxsci/kfi331