• Natural Product Sciences
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• 제12권3호
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• pp.162-165
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• 2006

Curcuma aeruginosa Roxb. (FamilyZingeberaceae), commonly known as 'pink and blue giner' is widely used in Indian system of medicine since time immemorial. The plant is found well in wild habitat and cultivated in southern India. The plant is distinguished by red corolla lobes and ferruginous or greenish-blue rhizome. Rhizoma is used medicinally as anti-diarrheal, anti-fungal; external use as astringent for wounds. A detailed pharmacognostic evaluation of its rhizome showed total ash 6.1%, acid insoluble ash 1.20%, alcohol soluble extractives 3.70% , water soluble extractives 14.50%, sugar 20.93%, starch 41.85%, and tannins 0.68%. Oh hydro distillation, the rhizomes and sessile tubers yielded 0.17% oil.

• 생약학회지
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• 제33권3호통권130호
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• pp.169-172
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• 2002

Chinese crude drug 'To Bog Ryung' has been to cure chronic aperient, syphilis cough and diabetes. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of To Bog Ryung, the morphological and anatomical characteristics of the rhizomes of Smilax species growing in Korea, i.e. S. china, S. riparia var. ussuriensis, S. nipponica, S. sieboldii were compared. As a result, it was determined that To Bog Ryung was the rhizome of Smilax china and Smilax sieboldii.

• 생약학회지
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• 제39권3호
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• pp.208-212
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• 2008

Seung Ma(升摩) is a famous Chinese crude drug used for treatment of fever, piles and suppurative inflamation. With regard to the botanical origin of Seung Ma, it has been considered to be Cimicifuga spicies of Ranunculaceae, but there has no phrarmacognostical confirmation on it. To clarify the botanical origin of Seung Ma from Korea, the anatomical characteristics of Cimicfuga dahurica, Cimicifuga foetida, Cimicfuga heracleifolia and Cimicifuga simplex were studied. As a result, it was clarified that Seung Ma from Korea was the rhizomes of Cimicifuga dahurica, C, foetida and C, heracleifolia.

• Archives of Pharmacal Research
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• 제12권3호
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• pp.196-200
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• 1989

The methanolic extract of the Rhizome of Curcuma zedoaria exhibited a significant prolongation of hexobarbital (HB)-induced hypnosis. Through liquid chromatography of an ether soluble fraction. monitoring by bioassay, three sequiterpenes, germacrone (A), curzerenone (B) and germacrone epoxide (C) were isolated as active consituents. A single treatment (100-200 mg/kg, i.p.) of each compound showed not only a significant prolongation of HB-induced sleeping time but also a significant inhibition of aminopyrine N-demethylase activity in mice, and further exhibited a typical type I binding spectra with oxidized rat hepatic cytochrome P-450 induced by phenobarbital. All of the compounds provoked a sleep episode at a subhypnotic dose of HB, implying that they possess CNS depressant properties.

• 생약학회지
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• 제26권4호
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• pp.411-418
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• 1995

In order to clarify the originality of several Alisma Rhizomes, we investigated the differences of their morphological, anatomical and physiochemical characteristics. Morphological observation shows the variability of Alisma shape and quality. The diversities in morphological shapes and qualities of tuber were observed among different origins. Chinese product looked like corm shape, but korean's irregular shape. The microscopic observation of korean Alisma revealed the presence of irregular vascular bundle which was scattered transversely and longitudinaly, which was different from that of the rhizome. This facts suggest that the portion of crude drug in Alisma should be the corm rather than the rhizome. In the physicochemical differences, chinese Alisma contains larger amount of mineral elements such as K, Na and Ca than korean Alisma. On the contrary, protein contents in lyophilized powder of aqueous extracts in korean Alisma rhizome was significantly higher than chinese Alisma rhizome. The leaves and stems contained larger amount of Ca and Na than tuber, and may be used as the osmotic diuretics for chinese traditional medicine.

• 한국한의학연구원논문집
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• 제9권1호
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• pp.113-122
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• 2003

In the present paper, morphological characteristic and PCR analysis were carried not to identify the medicinal origins of Peucedanum decursivum and Anthriscus sylvestris. Some samples in Korean. markets were Peucedanum decursivum misused with rhizomes of Anthriscus sylvestris. The main. origin of Peucedanum decursivum producted was quite different from those of Anthriscus sylvestris in the morphological characteristics. And PCR analysis, the three primer has developed into anew tool for identification of Peucedanum decursivum and Anthriscus sylvestris.

• Natural Product Sciences
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• 제21권3호
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• pp.147-149
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• 2015

Two terpenoids, including one uniquely aromatized one (1), were isolated from CH₂Cl₂-soluble fraction of MeOH extracts of Curcuma zedoaria. They were identified to be a sesquiterpene ketolactone (1) and orobanone (2), respectively on the basis of their NMR data. The structure of compound 1 was confirmed by X-ray chrystallography and the reported NMR assignments for 1 were revised in this study. Antibiotic activities for compounds 1 and 2 were evaluated using disk diffusion assay. Compound 1 showed potent antibacterial activities against Listeria monocytogenes and Staphylococcus pseudointermedius while compound 2 was active against Bacillus cereus.

• Natural Product Sciences
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• 제9권2호
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• pp.109-111
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• 2003

A bioassay-guided fractionation of the active chloroform extracts of the rhizomes of Zingiber cassumunar Roxb. led to the isolation of a potential cytotoxic principle, curcumin (1), along with two inactive compounds, (E)-4-(3',4'- dimethoxyphenyl)but-3-en-1-ol (2) and (E)-4- (3',4'-dimethoxyphenyl)but-3-en-1- yl acetate (3). Curcumin (1) showed a significant cytotoxicity against several human cancer cell lines $(Col2;\;2.30,\;A549;\;12.30,\;SNU638;\;IC_{50}\;18.80\;{\mu}g/ml)$.

• Journal of Plant Biotechnology
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• 제6권3호
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• pp.181-188
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• 2004

Zingiber officinale buds from the rhizomes were used to produce in vitro shoots. These explants produced the largest number of multiple shoots, 9.8 shoots per explant, when were cultured on MS (Murashige and Skoog 1962) medium supplemented with 2.0 mg/L benzyladenine (BA) and 2.0 mg/L indole butyric acid (IBA). This medium was also found to be suitable for in vitro propagation of other Zingiberaceae species: Alpinia conchigera, Alpinia galanga, Curcuma domestica, C. zedoaria and Kaempferia galanga. Both C. domestica and C. zedoaria produced more multiple shoots when were cultured in the liquid proliferation medium, MS medium containing 2.0 mg/L BA and 2.0 mg/L IBA. To maintain the in vitro plantlets of Zingiberaceae species, they were required to subculture every four weeks. After executing proper acclimatization protocol, in vitro plantlets of Alpinia galanga, A. conchigera, Curcuma domestica, C. zedoaria, Kaempferia galanga and Zingiber officinale could be successfully planted in the field with high percentage of survival.

• Archives of Pharmacal Research
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• 제28권5호
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• pp.592-597
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• 2005

An HPLC/Esl/MS method has been developed to identify and quantify the spirostanol glycosides in the rhizomes of five Polygonatum species. The relative distribution of two steroidal saponins in each extract was established using the selective ion monitoring (SIM) mode via an electrospray ionization (ESI) source. It was found that there were significant differences in the amount of spirostanol glycosides among the Polygonatum Species. The results showed that this method could be used to identify the steroidal saponins in the extracts and differentiate Polygonatum species with high sensitivity and reproducibility in a short time. Fragmentation patterns of the two reference compounds were also discussed with the electrospray ionization multi-stage tandem mass spectroscopy (ESI-MS$^n$).