• Proceedings of the Korean Journal of Food and Nutrition Conference
• /
• 2000.12a
• /
• pp.55-55
• /
• 2000

본 연구에서는 전통적으로 담석증, 신장치료 등의 한약제로 많이 사용하는 대왕을 여러 용매를 사용하여 얻은 대왕추출물 분액에 대한 세포독성을 여부를 MTT 정량법, NR 정량법, SRB 정량법을 이용하여 조사하였다. 1. 추출 용매 methylene chloride, ethyl acetate, butanol, water로부터 얻은 대왕추출물 모두 처리농도에 따라 세포에 미치는 영향이 증가하였다. 2. Butanol을 용매로 사용하여 얻은 대왕추출물 분액이 다른 3가지 용매로부터 얻은 대왕추출물보다 세포에 미치는 영향이 크게 나타났고 water를 용매로 사용하여 얻은 추출물이 A498 세포주에 미치는 영향이 가장 낮게 나타났다. 3. Butanol을 추출 용매로 하여 얻은 대왕추출물이 A498 세포주에 미치는 영향이 가장 컸는데 그 추출물에 대한 MTT50, NR50, SRB50값은 각각 0.63mg/m1, 0.65mg/ml, 0.68mg/ml이었고, 가장 영향이 적은 water의 경우 MTT50, NR50, SRB50값은 각각 0.84mg/m1, 0.82mg/m1, 0.80mg/ml이었다. 4. 정량방법 간의 대왕추출물에 대한 반응은 MTT 정량법이 가장 민감하게 나타났다.

• Korean Journal of Oriental Medicine
• /
• v.10 no.2
• /
• pp.101-108
• /
• 2004

A variety of Rhei Rhizoma are in circulation in the herbal medicine markets. The most of them were below the standard according to the Korea Pharmacopoeia. The rhizomes of Rheum undulatum, which is not recorded as the origin of Rhei Rhizoma in the Korea Pharmacopoeia, were the most common in Korean herbal medicine markets.

• Korean Journal of Pharmacognosy
• /
• v.28 no.4
• /
• pp.167-173
• /
• 1997

We have tested 101 species traditional medicinal plants on Acetylcholinester ase inhibition. Among them. Caesalpina sappan. Cnidium offcinale, Coptis japonica, Ephedra sinica, Eribotrya japonica, Gardenia jasminoides, Liriope platyphylla, Lonicera japonica, Paeonia suffruticosa, Phyllostachys nigra, Polygonum multiflorum, Prunella vulgaris, Rheum undulatum, Salvia miltiorrhiza and Uncaria rhynchophylla showed strong inhibition potency over 88%. In addition, Aconitum carmichaeli, Caesalphina sappan, Cinnamomun japonica, Citrus unshiu, Hordeum vulgare, Glycine max and Rehmannia glutinosa showed relatively good inhibition potency over 80%.

• Korean Journal of Food Science and Technology
• /
• v.29 no.5
• /
• pp.860-868
• /
• 1997

The effects of oil unsaponifiables (8 species) and methanolic plant extracts (53 species) on the thermal oxidation of oils during 14 or 16 hour heating at $180^{\circ}C$ were studied by analyzing the fatty acid composition of soybean oil or cottonseed oil. All the unsaponifiables tested did not show any antioxidative activities on the thermal oxidation of soybean oil. However, among the 53 species of methanolic plant extracts, some species (Rheum undulatum L., Chelidonium majus L. var. asiaticum and Eugennia caryopyllata T.) showed very strong antioxidative activities on the thermal oxidation of cottonseed oil. The antioxidative activities of methanolic extracts of these 3 species on thermal oxidation of cottonseed oil during an extended heating period were also studied by heating cottonseed oils for 7 hours a day for 8 days at $180^{\circ}C$. The methanolic extracts of Chelidonium majus L. v. asiaticum and Eugennia caryopyllata T. greatly reduced both polymer formation and linoleic acid decomposition after the 8 day heating at $180^{\circ}C$. However, the methanolic extracts of Rheum undulatum L. was effective for the reduction of polymer formation, but not for the reduction of linoleic acid decomposition.

• Food Science of Animal Resources
• /
• v.22 no.2
• /
• pp.183-191
• /
• 2002

The Mongolian milk processing technology has a specific characteristic as a result of the living habits of Central Asian nomads. There are many kinds of milk products in Mongolia due to their processing activity used milk from various dairy animal species. Mongolia has over 30 kinds of dairy products and fermented milk products which are occupied more than 36% of the Mongolian dairy products. Herdsmen who engaged extensive livestock production have specific methods to conserve and prepare the starter culture of fermented milk products in nomadic condition. Specifically, Mongolian lactic starter cultures were prepared from keeping milk products and specific wild plants. Nowadays, over 5 kinds of wild plants such as Rheum undulatum L. Rheum ribes L, Rumex acetosa L. Artemisa sibersena L, Artemisa vulgare are used for lactic starter preparing. Traditional processing methods of the Mongolian fermented milk products are based on the scientific basis and there are easy to learn and operate.

• The Journal of Korean Medicine
• /
• v.20 no.3 s.39
• /
• pp.87-93
• /
• 1999

Objectives: This study was conducted to analyze scientifically the purgative action of Chungpesagan-tang, which was widely used for stroke In Oriental Medicine. Methods: The contents of sennoside A on the water-extraction of Rhei Rhizoma, the transforming activity of sennoside A to rheinanthrone by human intestinal bacteria, and the anti-costive activity of Chungpesagan-tang, Rhei Rhizoma and Yuldahanso-tang on mice were investigated. Results: Rhei Rhizoma (Rheum palmatum, from China) had dose-dependent potent purgative action. Chungpesagan-tang containing this Rhei Rhizoma had more potent purgative action than Rhei Rhizoma only. However, Korean cultivated Rhei Rhizoma (Rheum undulatum) and Chungpesagan-tang containing this Korean cultivated Rhei Rhizoma had no purgative action. Conclusions: These results suggest that Chungpesagan-tang polyprescription should be considered to enhance the purgative action of Rhei Rhizoma.

• Applied Biological Chemistry
• /
• v.41 no.8
• /
• pp.600-604
• /
• 1998

Methanol extracts from 53 species of oriental medicinal plants in 34 families were tested for their fungicidal activities against Pyricularia grisea, Rhizoctonia solani, Phytophthora capsici, Phytophthora infestans, Collectotrichum dematium, Botryospaeria dothidea, Fusarium oxysporum f. sp. cucumerinum, Botrytis cinerea, Puccinia recondita, and Erysiphe graminis. In in vitro study using impregnated paper disc method, the efficacy varied with both plant pathogen and plant species tested. Methanol extracts of Asarum sieboldii roots, Sinomenium acutum roots, Pinus densiflora leaves, Rheum undulatum root barks, Coptis japonica roots, and Phellodendron amurense barks showed potent fungicidal activities against the various pathogens when treated with 10 mg/disc. In a whole plant test, methanol extracts of P. densiflora leaves and roots and C. japonica roots were highly effective against a variety of plant pathogens. As a naturally occurring fungicide, P. densiflora- and C. japonica-derived materials could be useful as new fungicidal products against various plant diseases induced by plant pathogenic fungi.

• Korean Journal of Pharmacognosy
• /
• v.39 no.3
• /
• pp.179-185
• /
• 2008

Three species, such as Rheum palmatum L., R. tanguticum Maxim. and R. officinale Baillon are recognized as the source plants of Rhei Rhizoma in Korean Pharmacopeia. However, other herbal sources such as R. undulatum L. and Rumex crispus L. have been often misused as Rhei Rhizoma. A pattern analysis method to discriminate Rhei Rhizoma in Korean Pharmacopeia from other herbal plants using HPLC and TLC chromatograms was developed. The multivariate peak data of the chromatograms of methanol extracts of Rhei Rhizoma were used for hierarchical clustering analysis, principal components analysis and similarity calculation. Besides of the statistic analysis, TLC patterns of samples could be used as criteria of the discrimination. The developed pattern analysis method was specific and could be readily utilized for comprehensive evaluation of Rhei Rhizoma.

• Natural Product Sciences
• /
• v.2 no.1
• /
• pp.56-74
• /
• 1996

Prostaglandin $H_2$ synthase is the pharmacological target site of nonsteroidal antiinflammatory drugs. Inhibitory effects on cyclooxygenase activity of the synthase by extracts prepared from herbal medicines and wild plants in Korea have been estimated. Sixteen species out of 612 species exhibited more than 50% of inhibition on the enzyme activity. The active extracts prepared from Carex humilis, Celastrus orbiculatus, Eugenia caryophyllata, Gleditsia japonica var. koraiensis, Glycyrrhiza grabra, Glycyrrhiza uralensis, Gyrophora exculenta, Lespedeza maximowiczii, Morus alba, Persicaria conspicua, Prunus salicina, pterocarya stenoptera, Rheum undulatum, Vitis amurensis, and Vitis coignetiae have been sequentially washed with methylene chloride, ethyl acetate, n-butanol. Among the solvent fractions of the active herbal extracts, ethyl acetate fraction of Carex humilis exhibited the highest inhibitory effect on the cyclooxygenase activity of prostaglandin $H_2$ synthase.

• Journal of Korean Medical classics
• /
• v.25 no.1
• /
• pp.117-139
• /
• 2012

Objective : In this study, I would like to emphasize the importance of context in studying quoted verses in "Donguisusebowon". Method : First, methodology applied in researches on "Donguisusebowon" quotations were organized. Next, in order to examine the effects of the aforementioned methodology, several quoted verses were approached in such method. Result : First, the verse, 'In cases of Dry-Feces(大便秘燥), Rheum undulatum Linne(大黃) could be used in the medicinal formulas and treatment, but not Croton tiglium Linne(巴豆)'. In the texts of Shanghanlun(傷寒論), Zhang, Zhongjing(張仲景) prescribed Sammulbaeksan(三物白散) in treating 'Gyeolhyung due to Excessive cold'(寒實結胸), which includes Croton tiglium Linne(巴豆). From this, we can see that Lee, jema's statement in "Donguisusebowon" is false. Conclusion : Lee, jema's mistake was that he accepted Shanghanlun(傷寒論) as quoted in "Donguibogam", instead of the original text, accidently quoting Heo, jun's source of reference.