• 제목/요약/키워드: Reversal Method

검색결과 245건 처리시간 0.027초

Induction of Primary Male in Juvenile Red Spotted Grouper Epinephelus akaara by Immersion of $17{\alpha}$-Methyltestosterone

  • Lee, Chi-Hoon;Hur, Sang-Woo;Na, Oh-Soo;Baek, Hae-Ja;Noh, Choong-Hwan;Han, Sang-Hyun;Lee, Young-Don
    • 한국발생생물학회지:발생과생식
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    • 제18권3호
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    • pp.127-131
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    • 2014
  • We investigated the androgenic effects of $17{\alpha}$-methyltestosterone (MT) on gonadal sex reversal in juvenile red spotted grouper Epinephelus akaara. The fish were immersed in $17{\alpha}$-MT at 1 and 5 mg/L. Treatment method of $17{\alpha}$-MT was once weekly for 4 and 8 weeks. Fish were sampled at 12 months after end of the treatment period in order to histological analysis. At the initiation of an experiment (70 day after hatching), juvenile red spotted grouper have the paired primordial gonads with somatic cells bellow kidney in the posterior portion of the body cavity. Formation of ovarian cavity indicates that the ovarian differentiation beginning at 70 DAH in red spotted grouper. At 12 months after end of the treatment period, control group, $17{\alpha}$-MT 1 mg/L treatment group for 4 and 8 weeks, and $17{\alpha}$-MT 5 mg/L treatment group for 4 weeks were all female. However, sex-changed males without ovarian cavity were observed in the $17{\alpha}$-MT 5 mg/L treatment group for 8 weeks. In grouper, we firstly reported that the red spotted grouper be able to induce the primary males by hormone treatment prior to gonadal sex differentiation.

알로스테시스 과부하와 칠정상에 관한 비교 고찰 (Comparative Study between the Allostasis Load and Chiljeongsang)

  • 정진용;김준영;조정효;손창규
    • 동의생리병리학회지
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    • 제30권6호
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    • pp.452-457
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    • 2016
  • If human body is exposed to the continuous stress, it becomes allostasis load which is the condition of homeostasis broken. Its evolutional ecologic point of view and the relation with chiljeongsnag which is a theory in Oriental Medicine were investigated. Upon evolutional ecologic point of view by Maynard Smith, people can be divided by Hawks and Doves resulting in different types of allostasis in response of the stress. Hawks people who are active and aggressive get easily anger in the stressful situation to be vulnerable to the inflammatory hepatic diseases by enhancing Th1 immune system. On the other hand, Doves people who are passive and calm get easily depressed with sadness in the stressful situation to be vulnerable to the allergic pulmonary diseases by enhancing Th2 immune system. According to constitution theory of Oriental Medicine, Yangin and Eumin show the different features of responses to the stress generating Chiljeongsang. With excessive stress continuously, Yangin consider the feeling of anger mainly resulting in Qi reversal and liver damage, while Eumin consider the feeling of sadness mainly in consumption of Qi and lung damage. Hawks and Yangin, and Doves and Eumin show the common behaviors in response to the stress demonstrating the similar features including allostasis load and Chiljeongsang. In the clinical practices with the stressful patients, the viewpoint to consider the behaviors and feelings of the subjects to receive the stress simultaneously can be the new approaching method in Psychosomatic Medicine.

제한면을 가지는 이차원 난류 충돌젯트의 유동 및 열전달 특성의 수치적 연구 (A Numerical Study of the Fluid Flow and Heat Transfer Characteristics of the Two-Dimensional Turbulent Impingement Jet with a Confinement Plate)

  • 강동진;오원태
    • 대한기계학회논문집
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    • 제19권7호
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    • pp.1675-1683
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    • 1995
  • A numerical study of the fluid flow and heat transfer characteristics of the two-dimensional impingement jet with a confinement plate has been carried out. The fluid flow was calculated by solving the full Navier-Stokes equation. In doing that, the well known SIMPLER algorithm was used and the trouble making convection term was discretized according to QUICKER scheme. The energy equation was simply solved by using the SOR method. For the Reynolds number of 10000, two channel heights, say 1.5 and 3.0 times the jet exit width, and two thermal boundary conditions constant wall temperature and constant wall heat flux were considered. Discrete heat sources were flush mounted along the impingement plate at a distance of 0, 2, 3, 4, 5, 6, 10, 12, times the jet exit width from the stagnation point. The length of each heat source is 4 times the jet exit width long. The Nusselt number averaged over each heat source was compared with experiment. Comparison shows that both calculations and experiment have the secondary peak of Nusselt number at downstream of stagnation point, even though there is a little quantitative difference in between. The difference is believed due to abscure thermal boundary condition in experiment and also accuracy of turbulence model used. The secondary peak is shown to be caused by rigorous turbulent flow motion generated as the wall jet flow is retarded and developes into the channel flow without flow reversal.

Analysis of demountable steel and composite frames with semi-rigid bolted joints

  • Wang, Jia;Uy, Brian;Li, Dongxu
    • Steel and Composite Structures
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    • 제28권3호
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    • pp.363-380
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    • 2018
  • This paper presented an integral design procedure for demountable bolted composite frames with semi-rigid joints. Moment-rotation relationships of beam-to-column joints were predicted with analytical models aiming to provide accurate and reliable analytical solutions. Among this, initial stiffness of beam-to-column joints was derived on the basis of Timoshenko's plate theory, and moment capacity was derived in accordance with Eurocodes. The predictions were validated with relevant test results prior to further applications. Frame analysis was conducted by using Abaqus software with material and geometrical nonlinearity considered. Variable lateral loads incorporating wind actions and earthquake actions in accordance with Australian Standards were adopted to evaluate the flexural behaviour of the composite frames. Strength and serviceability limit state criteria were utilized to verify configurations of designed models. A wide range of frames with the varied number of storeys and bays were thereafter programmed to ascertain bending moment envelopes under various load combinations. The analytical results suggest that the proposed approach is capable of predicting the moment-rotation performance of the semi-rigid joints reasonably well. Outcomes of the frame analysis indicate that the load combination with dead loads and live loads only leads to maximum sagging and hogging moment magnitudes in beams. As for lateral loads, wind actions are more crucial to dominate the design of the demountable composite frames than earthquake actions. No hogging moment reversal is expected in the composite beams given that the frames are designed properly. The proposed analysis procedure is demonstrated to be a simple and efficient method, which can be applied into engineering practice.

박리성 대동맥류(DeBakey Type III)의 외과적 치험 -2예보고- (dissecting aortic aneurysm (DeBakey Type III) -Report of two cases-)

  • 문경훈
    • Journal of Chest Surgery
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    • 제19권3호
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    • pp.443-448
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    • 1986
  • Aortic dissection is a serious disease that mortality does not approach to zero despite of medical and surgical improvement. Recently two cases of aortic dissection were treated with good results by the two other methods. Case 1 [57-Y-0-Male]; Chief complaint was chest pain radiating to the back. Preoperatively he was controlled by Minipress, dichlotride, & sodium nitroprusside. Aortography showed DeBakey Type III aortic dissection extending from just below the Lt. subclavian artery to the proximal portion of the origin of the renal artery. Through the midline long incision Flow reversal & Thrombo-exclusion method was used, and bypass course was proximal anastomosis at the ascending aorta - through the Rt. thoracic cavity - midportion of the diaphragm - posterior to the liver, stomach, & pancreas - distal anastomosis at the abdominal aorta proximal to its bifurcation. Bypass graft was preclotted 20 mm Dacron Woven Graft, and the aortic arch between the Lt. subclavian artery & Lt. common carotid artery was divided and meticulously sutured. Control aortogram which was done at 4th postoperative month revealed obstruction of the false lumen by thrombosis, and complications were not noticed. Case 2 [53-Y-0-Male]; Chief complaint was chest pain radiating to the abdomen. DeBakey Type III aortic dissection which was similar to the case 1 was detected by the aortography, and involvement of the Lt. subclavian & common carotid arteries was suspicious. Through the Lt. posterolateral thoracotomy the Ringed Intraluminal Sutureless Graft, No. 22 mm, was inserted from just below the Lt. common carotid artery to the midportion of the descending thoracic aorta under total circulation arrest using a F-F bypass, and the Lt. subclavian artery was ligated. Postoperatively hospital course was uneventful with antihypertensive drugs, and any specific complications were not noticed.

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혁신지향 조직문화가 경영성과에 미치는 영향 -진취적 기업가행동과 시장지향성의 매개효과를 중심으로- (The Influence of Innovation-oriented Organizational Culture on Management Performance - Focusing on the Mediating Effect of Proactive Entrepreneurial Behaviour and Market Orientation -)

  • 주철근
    • 디지털융복합연구
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    • 제18권8호
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    • pp.119-131
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    • 2020
  • 스타트업이 전통적 거대기업을 물리치는 역전현상의 원인으로, 기업가정신과 시장지향이 조직문화와 경영성과 관계에 미치는 매개효과를 살펴보는 것이 본 연구의 목적이다. Hayes(2013년)가 제안한 부트스트래핑의 연구방법을 통해 총효과, 직접효과, 간접효과 분석을 실시했다. 그 결과 조직문화와 경영성과 사이에는 직접적인 영향관계가 없었지만, 조직문화와 경영성과의 관계에서 기업가적 행동과 시장지향성을 모두 매개함으로써 경영성과에 긍정적인 영향을 미친다는 것을 확인했다. 본 연구는 기업가정신과 시장지향성 등 기존 이론과 연계하고 기업성과에 필요한 역량목표의 범위를 조직문화로 확대하였다는 점에서 의의가 있다. 기업은 경영성과와 가치창출을 위한 혁신지향적 조직문화를 창출하고 기업가적 행동과 시장지향성을 가지고 조직의 관성으로부터 문화를 개방할 필요가 있다.

Antiferroelectric Liquid Crystal from Bent-Core Molecule with Vinyl End Group

  • Lee, Chong-Kwang;Kwon, Soon-Sik;Kim, Tae-Sung;Shin, Sung-Tae;Choi, Hong;Choi, E. Joon;Kim, Sea-Yun;Zin, Wang-Choel;Kim, Dae-Choel;Chien, Liang-Chy
    • Bulletin of the Korean Chemical Society
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    • 제25권8호
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    • pp.1171-1176
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    • 2004
  • Three banana-shaped achiral compounds, 4-chloro-1,3-phenylene bis [4-{4-(undecenyloxy)phenyl imino-methyl} benzoate] derivatives, were synthesized with variation of a substituent (x=H, F, Cl); their antiferro-electric properties are described. The smectic mesophases, including a switchable chiral smectic C(Sm $C^{\ast}$) phase, were characterized by differential scanning calorimetry, polarizing optical microscopy, triangular wave method, and X-ray diffractometry. The presence of vinyl groups at the terminals of linear side wings in the banana-shaped achiral molecules induced a decrease in melting temperature and formation of the switchable Sm $C^{\ast}$ phase in the melt. The smectic phase having a lateral fluorine-substituent at 3-position of the Schiff's base moiety showed antiferroelctric switching, and the value of spontaneous polarization on reversal of an applied electric field was 250 nC/$cm^2$ .

스퍼터 제조조건에 따르는 SmCo/Cr 박막의 자기적 특성에 관한 연구 (Effects of Deposition Conditions on Magnetic Properties of SmCo/Cr)

  • 나태준;고광식;이성래
    • 한국자기학회지
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    • 제9권6호
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    • pp.312-320
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    • 1999
  • RF 마그네트론 스퍼터링으로 제조한 SmCo/Cr 박막의 스퍼터 제조조건에 따르는 자기적 특성에 관하여 연구하였다. Sm 조성이 약 20 at %이고 Cr(50 nm)/SmCo(40 nm, 50W, 20mT)/Cr(150 nm, 100W, 30 mT)인 조건에서 제조한 시편에서 3.2 kOe의 최대 보자력을 얻었다. SmCo/Cr의 보자력은 하지층 표면거칠기와 SmCo의 조성에 크게 영향을 받았다. Cr 하지층의 거칠기는 Ar 분압과 두께가 증가할수록 증가하고 이는 SmCo 입자의 고립을 증가시켜 보자력이 증가된다. 본 SmCo 박막 증착시 사용한 RF 투입전력 및 Ar 분압은 SmCo의 조성을 변화시키며 최적의 조성(약 20 at.%Sm)에서 최대 보자력을 보인다. 또한 RF 파워 증가나 Ar 분압 증가에 의해 생긴 Cr 하지층의 표면거칠기, 치밀하지 않은 주상 계면구조등의 결함이 자구벽 이동을 방해하여 보자력 증가에 영향을 끼친다.

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Effects of the Instrument Pilates Exercise Based on the Schroth Exercise on the Cobb's Angle, Angle of Trunk Rotation and Low Back Pain in Patients with Idiopathic Scoliosis: A Single Subject Study

  • Song, Ki Yeon;Baek, Ki Hyun;Lim, Mi Soo;Lim, Hyoung-won
    • The Journal of Korean Physical Therapy
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    • 제33권2호
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    • pp.97-105
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    • 2021
  • Purpose: This study examined the effects of the application of Schroth exercise-based instrument Pilates exercise on the Cobb's angle, angle of trunk rotation, and low back pain of female patients with idiopathic scoliosis. Methods: Three patients with idiopathic scoliosis at a Cobb's angle of 20° or more participated in this study. Among the single-subject experimental research designs, a reversal (ABA) design was performed. In particular, Schroth exercise-based instrument, Pilates exercise, was performed for 10 weeks, consisting of five weeks between the baseline and intervention one period and five weeks between the intervention 1 and intervention 2 periods, and then followed up for five weeks. Results: After the Schroth exercise-based instrument, Pilates exercise, was applied, the Cobb's angle and the angle of trunk rotation decreased compared to the baseline in all subjects, and the follow-up period also showed a continuous decline. After Pilates exercise was performed, low back pain in subjects 1 and 2 was decreased in the intervention 1 period compared to the baseline. The level of low back pain in the intervention 2 period increased compared to the intervention 1 period, but a reduction was noted in the follow-up period. The low back pain in the subject was decreased in all intervention periods and the follow-up period. Conclusion: Schroth exercise-based Pilates exercise improves the Cobb's angle and the angle of trunk rotation for female patients with idiopathic scoliosis in their teens and 20s, and an effective intervention method is proposed for low back pain.

The Effect of 16 Weeks of Modified Apparatus Pilates Exercise on Cobb's Angle, Trunk Rotation Angle, and Depression in Patients with Idiopathic Scoliosis

  • Ki Yeon Song;Ki Hyun Baek;Mi Soo Lim;Hyoung-Won Lim
    • The Journal of Korean Physical Therapy
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    • 제35권4호
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    • pp.95-104
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    • 2023
  • Purpose: This study was undertaken to identify the effects of apparatus Pilates exercise on Cobb's angle, angle of trunk rotation, and depression in female patients with idiopathic scoliosis. Methods: Participants included five patients with idiopathic scoliosis presenting with Cobb's angle of 10 degrees or more. Among the single-subject experimental research designs, the reversal (ABA) design was selected and performed. The apparatus Pilates exercise was performed for a total of 16 weeks, comprising 8 weeks between the baseline and intervention 1 period and 8 weeks between intervention 1 and intervention 2 periods. The patients were then followed up for 5 weeks. Results: In all subjects, compared to the baseline, Cobb's angle and the angle of trunk rotation decreased after application of the apparatus Pilates exercise. The follow-up period also showed a similar continuous decline. Following the apparatus Pilates exercise, the depression scale in subject 3 was increased during the intervention 1 period as compared to the baseline. However, the patient displayed a reduced depression scale in intervention 2 and follow-up periods. The depression scale in all other subjects was decreased for both intervention periods and the follow-up period. Conclusion: The application of apparatus Pilates exercise improves Cobb's angle and the angle of trunk rotation for female patients with idiopathic scoliosis in their 10s and 20s. Our results also indicate that this is potentially an effective intervention method to overcome depression.