Journal of the Korea Academia-Industrial cooperation Society
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v.21
no.5
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pp.327-336
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2020
This study was undertaken to identify ways that enable a successful comeback to everyday life and improvement in the quality of life, by understanding the experiences of cancer survivors in returning to everyday life. Totally, 19 people diagnosed with complete cure after 5 years of cancer treatment, were recruited for the study. Data was collected through in-depth interviews from January 18 to February 25, 2017. One-time interviews took 90 to 120 minutes, and data analysis was achieved by applying the grounded theory. The central phenomenon of 'reality that cannot be escaped' and 'uncertain reality that cannot know tomorrow' was attributed to the causal conditions 'hard reality', 'physical exhaustion', 'psychological exhaustion' and 'economic exhaustion'. Depending on context conditions such as 'lack of family support', 'shift to a vulnerable working class', 'insufficient support system', 'hope for the societal support system', 'daunted gender', 'prejudice against cancer/cancer patients', 'information on life after rare full healing'. The strategy for a successful return was influenced by intervention conditions such as 'robust family fence' and 'effective cancer insurance', which resulted in 'building a new life' or 'enduring'. We conclude that for a successful return to daily lives, cancer survivors require comprehensive information, health and social-welfare interventions.
In this paper, the performances of implementation real-time book search service of government library using OpenAPI. Since 2000, each self-government made a governmnt library for local resident because of policies to encourage reading. Each self-government library services book perusal and lend free for local resident. In current system local residents visit to a library for lending, returning and reading books. And each library run by a self-governing administration provides their own homepage for searching service as well as booking. For each services are not unified, however, it is not easy for lenders to search and lend these enormous books which are spread each library. Accordingly, we present a plan which using organization of every system established now in each library as it is, for a scheme of database by libraries' efficient unification and search, a network of TCP/IP and application which connects each library's database, servicing which uses Open API a check books through real time accessing Database.
Kim, Tae Joon;Ko, Yong;Kim, Young Soo;Oh, Seong Hoon;Kim, Kwang Myung;Kim, Nam Kyu;Oh, Suck Jun
Journal of Korean Neurosurgical Society
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v.29
no.5
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pp.635-639
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2000
Objective : Surgery for the microvascular decompression is mostly concerned with injury to the cranial nerves or brain stem by cerebellar retraction. Intraopeartive brain stem auditory evoked potentials(BAEPs) has been continuously monitored on surgery to evaluate the extent of injury, recovery of the nerves and prognosis. Methods : Of the 161 cases of CP angle surgery from Feb. 1996 to Apr. 1998, 103 cases were monitored during operation. Thirty five patients who had undergone similar surgery were selected and evaluated ; 23 patients were monitored and 12 were not during surgery. If monitor showed more than 0.5 mSec delay of latency, surgeon was given a warning not to retract brain any more. If more than 1mSec delay, surgeon was informed to stop surgery and wait for the returning of evoked potentials. The level of amplitudes and delay of latencies during the initial stage of operation, opening the dura, insertion of teflon patches, and closing the dura and recovery were then compared. Resuls : Twenty patients were male and 15 were female. Their average age was 50.26 years. Mean amplitude during the initial stage of operation was $0.60{\pm}0.25mV$, at opening the dura $0.56{\pm}0.26$, after teflon patches insertion $0.49{\pm}0.20$, and after closure of dura $0.47{\pm}0.28mV$. Mean latency during the early stage of operation was $6.08{\pm}0.67mSec$, at opening of dura $6.38{\pm}0.55$, insertion of teflon $6.97{\pm}0.59$, and closing the dura $6.17{\pm}0.54$. There was statistical significance in the difference of amplitudes between each procedures, and in the difference of latencies. For the complete recovery of amplitude and latency, it usually took average 5.65 minutes(0-20 min). In monitored group, only one patient required more than 20 minutes to recover and suffered from hearing disturbance after surgery. Others were recovered within 10 minutes without complications. However, 4 out of 12 patients who were not monitored showed hearing disturbance, and 1 patient had temporary facial palsy and dizziness(p=0.000). Conclusion : The results indicate that continuous intraoperative monitoring of BAEPs during CP angle surgery is seen mandatory procedure to prevent operative complications.
Various housing measures are needed for the rapidly aging society of Korea. In particular, the welfare policy for the elderly has changed towards the community care. Taking this fact into consideration, it is necessary to have the establishment of a system that offers the elderly appropriate welfare services at their appropriate residence (ageing in place) for the effectiveness of the community care. In this aspect, there are a number of implications to Korea to study merits and demerits of the Health Facilities for the Aged (HFA) in Japan. The society of Japan has been rapidly aging since 1970, and Korea is to face the same situation. As for the data of this study, a total of 2,393 facilities (as of November 1999) mentioned in the annual report of the Japanese Ministry of Health, Labor and Welfare were classified based on types of their establishment: (1) free-standing structures (603 facilities); (2) annexes to hospitals (981 facilities); (3) annexes to welfare facilities (511 facilities); and (4) annexes to clinics (298 facilities). Next, 239 facilities were selected through taking a sample of 10 percent from each type of the HFA mentioned above. This was done through the random sampling method with the computer program of MS EXCEL. The Implications of the results of analyses are as follows. First, most of the health facilities were planned with the scale that was larger than the scale of standard special nursing homes in terms of the total floor area. Precise equations that were to obtain precise results of the scale of the HFA and the appropriate number of residents were obtained through the method of the regression analysis. Korea and Japan have similarities in terms of culture, society and family relations; however, the two countries also have differences in terms of the application of laws on the establishment of houses, hospitals, and welfare facilities. As for planning the scale of the HFA, the realities of Korea should be considered. Second, as for the functional aspect of the HFA with a condition of returning home, the place before and after the HFA showed the pattern of 'from a residential place to a residential place' and 'from a hospital to a hospital.' This reveals a close correlation with the types of the HFAs and operational ways of the facilities. Its cause is considered to be the aspect of the operation and management of the HFA rather than the aspect of its function of providing services in association with medical and health facilities. Therefore, when intermediate welfare facilities are considered in Korea, it is strongly advised to consider the problem of annexes to other facilities and efficiency of sharing of the facilities in terms of its operation and management.
B/K protein is a novel protein containing double C2-like domains. We examined the specific signaling pathway that regulates the transcription of B/K in PC12 cells. When the cells were treated with forskolin ($50{\mu}M$), B/K mRNA and protein levels were time-dependently decreased, reaching the lowest level at 3 or 4 hr, and thereafter returning to the control level. Chemicals such as dibutyryl-cAMP, cellpermeable cyclic AMP (cAMP) analogue and CGS21680, adenosine receptor $A_{2A}$ agonist, also repressed the B/K transcription. However, 1,9-dideoxyforskolin did not show inhibitory effect on B/K transcription, suggesting direct involvement of cAMP in the forskolin-induced inhibition of B/K transcription. Effect of forskolin, dibutyryl cAMP and CGS21680 was significantly reduced in PKA-deficient PC12 cell line (PC12-123.7). One cAMP-response element (CRE)-like sequence (B/K CLS) was found in the promoter region of B/K DNA, and electrophoretic mobility shift assay indicated its binding to CREM and CREB. Forskolin significantly suppressed the promoter activity in CHO-K1 cells transfected with the constructs containing B/K CLS, but not with the construct in which B/K CLS was mutated (AC:TG). Taken together, we suggest that the transcription of B/K gene in PC12 cells may be regulated by PKA-dependent mechanism.
Ahn, Jaehwan;Kang, Sungwon;Ahn, Kwangho;Kim, I tae;Kim, Seog gu;Ahn, Hosang;Lee, Youngsup
Journal of Korean Society of Environmental Engineers
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v.34
no.12
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pp.787-791
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2012
Characteristics of particle separation in water using labscale acoustic standing wave were studied. Acoustic standing wave is similar to either sound wave or ultrasonic, which makes a constant wave while returning to the origin by reflector. During that time, particulates dispersed in water are collected on the node of wave, where a sound pressure is zero. Acoustic standing wave transducer as of 28.0 kHz and 1.0 MHz were utilized and $6.8{\mu}m$ kaolin and $100.5{\mu}m$ redmud in average diameter were used as experimental materials in water. Once acoustic standing wave are generated in water, water temperature rises by $0.15{\sim}0.20^{\circ}C/min$ due to a sound pressure. Initial concentration of kaolin and redmud were controlled to have same as of 0.1, 0.2, 0.3, 0.4, 0.5 g/L, respectively. Removal efficiency of the turbidity in a reacting chamber after 5 minutes, when acoustic sound wave was formed in most distinct, was measured to have 18.2~56.2% for kaolin and 23.0~53.6% for redmud at 1.0 MHz. Particle separation was not observed at 28.0 kHz.
Two polyethylene tubes were inserted into the esophagus of anesthetized rabbit in order to record the fluctuation of the intraluminal pressure through the orifices located near the tips of the tubes. The orifice of the first tube was 10 cm apart from the incisor of the rabbit and the orifice of the second tube was 5 cm below that of the first one. The tubes were filled with saline solution running at various rates ranging from 1.5 ml/min. to 4.2 ml/min. The tubes were connected to the pressure transducers and the electrical signals were recorded by the physiograph. When the peristaltic wave approached to the orifice a rise in the pressure was recorded, returning to the base line when the portion of the orifice was quiescent. The frequency of the peristaltic motion and the velocity of the wave were studied in connection with the flow rate of saline solution through the tubes and in the case of massive acute hemorrhage. The results obtained were as follows: 1. There was reflux of fluid induced during the procedure of the experiment. This outwrad flow through the pharynx seemed to elicite swallowing reflexes. Accordingly, the frequency of peristalsis of the esophagus was largely dependent on the flow rate of the fluid through the inserted tubes. By the flow rate of 1.5 ml/min., 2.5 ml/min., or 4.2 ml/min., the frequencies of the peristalsis were revealed to be $8.6{\pm}3.6/10min.,\;14.5{\pm}4.8/10min.\;or\;21.1{\pm}6.3/10min.,$ respectively. The velocity of peristalsis also coincided with the enhanced motility of the esophagus, showing $6.6{\pm}1.5\;cm/sec.,\;8.9{\pm}3.9\;cm/sec.,\;or\;12.4{\pm}4.6\;cm/sec.,$ respectively. 2. By acute hemorrhage, amounting to 2% of the body weight, the frequency of the peristalsis increased to twofold of the control and the propagation velocity also increased by 52 percent. 3. Retransfusion of the shed blood resulted in divergent responses. In some cases there were noticable ameliorations of the effects brought by acute hemorrhage, and in the others there were still increasing tendenies of the motility after the transfusion. 4. Some speculation was made about the possibility of a kind of relationship between the irreversibility of the hemorrhagic shock and the absence of responses by transfusion. 5. The peristalsis persisted even after complete disconnection at the midportion of the esophagus, reaffirming the view of a central regulation of the spatiotemporally coordinated motility, peristalsis.
In order to investigate the 'In Vitro 2-Cell Block' phenomenon found in certain mouse strains such as ICR, the present studies have been done. Fertilized eggs (1-cell) and 2-cell embryos recovered from the oviducts of the ICR mouse at the various time intervals after hCG injection to induce ovulation were cultured for 3 or 4 days to examine the capability for further cleavage beyond 2-cell stage. Consequently, it was found that some proportions of the 1-cell or 2-cell embryos recovered at 30 hours post hCG showed their cleaving capability and if the embryos were obtained after 48 hours of hCG injection, they were all at 2-cell stage and most of them developed to the blastocysts in vitro. It was also found that the embryos obtained at 27 hours post hCG showed their stronger capacity of further development in the groups cultured for shorter period than 24 hours in vitro before transferring to the oviduct. Based on the results, it can be inferred that mouse fertilized eggs should be remained inside the oviduct for a certain length of period after fertilization, or they should be cultured for a short period than 12 hours before returning back to the oviduct in order to develop to blastocysts. It was also found that though the embryos under the 2-cell block in culture showed normal feature up to 24 hours under the microscopical observation, they had already lost their capacity for the normal development, and if the culture of the 2-cell embryos was extended to 48 hours, they showed nuclei with heteropyknosis, and the vacuoles were were detected in the cytoplasm of embryonic cell if they were cultured for 72 hours.
Recently, there have been flood damages due to the climate change and the flash flood continuously in Korea and there are several flood disaster mitigation plans that are normally most of management plan for water related disasters even though drought disasters are as important as flood disasters. In this study, it is underlined that the research on solution of water shortness due to the drought disasters is currently required since the frequency of drought damage is not very many but continuously increasing. There was big drought damage in TaeBaek City of Kangwon province due to the serious lack of water during autumn, 2008 to spring, 2009. This study therefore analyses the characteristics of hydrometeorological conditions by rainfall frequency analysis and the operations of Gwangdong dam that is a source of multi-regional water supply by analysing water demand. As results of study, there was a drought with 20 years returning period which is not really available to fill the reservoir as usual and which could only filled 52% of reservoir. The rainfall during the dry season was less than normal, however, the water demand from the TaeBaek City was higher than normal. As researching several reasons of water shortness including the reasons described above, this study might be useful for drought mitigation plan.
Dr Lillehei (1918$\sim$1999) pioneered cardiac surgery with his landmark operations using cross-circulation in 1954 and 1955. With his dedications to open heart surgery, he is generally considered to be the father of open heart surgery by many medical historians. Dr Lillehei expanded his contributions to cardiac surgery with training 134 cardiothoracic surgeons at the University of Minnesota Hospital and he trained an additional 20 surgeons at the Cornell Medical Center. Dr Lillehei's trainees came from all over the world and Dr YK lee (1921$\sim$1994) of Seoul National University was among them. He joined the University of Minnesota Hospital in 1957 as a part of the Minnesota project. During his stay for two years, in addition to experimental research, he learned clinical cardiac surgery as part of Dr Lillehei's team. In 1959, after returning to Korea, Dr Lee began his career as. a full-time cardiac surgeon with establishing the Division of Cardiac Surgery at Seoul National University. Hospital. Yet he encountered many difficult barriers in the process. During that time, Dr Lillehei was willing to share his experience and he provided many valuable resources for cardiac operations. With Dr Lillehei's kind help, the open heart surgery program was gradually and successfully established at Seoul National University Hospital. These two surgical titans from across the Pacific Ocean died in 1994 (Dr Lee) and 1999 (Dr Lillehei). They are gone, yet the proud Korean people have not forgotten them.
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