• 제목/요약/키워드: Retardation coefficient

검색결과 46건 처리시간 0.025초

Study on the Biosynthesis on Neomycin: Characterization of Isocitrate Dehydrogenase of the Neomycin Producer, Streptomyces fradiae and its Possible Relation to the Regulation of Biosynthesis of Neomycin

  • Chang Hoon Lee;Yang Mo Goo;Kong Hwan Kim
    • Bulletin of the Korean Chemical Society
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    • 제12권5호
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    • pp.504-509
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    • 1991
  • S. fradiae showed very high activity of isocitrate dehydrogenase compared to other microorganisms. The activity of this enzyme was increased with the growth of the organism. But the increase might not imply its involvement in the growth. Rather its increased activity seemed to have a connection with the biosynthesis of neomycin. The enzyme showed high specificity toward $NADP^+$ and D-isocitrate with Km values of 5.75 and 6.74 uM, respectively, It was activated by $Mn^{2+}$. Its molecular weight was estimated from its gel retardation coefficient to be in the range of 61,000-63,000 daltons and its optimum pH was 8.0. The enzyme was thermally unstable.

Numerical Analysis for Contaminant Transport using a Dual Reactive Domain Model

  • 정대인;최종근
    • 한국지하수토양환경학회:학술대회논문집
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    • 한국지하수토양환경학회 2002년도 총회 및 춘계학술발표회
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    • pp.122-126
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    • 2002
  • Contaminant transport in porous media is characterized by solving an advection-dispersion equation(ADE). The ADE can cover equilibrium phenomena of interest, which include sorption, decay, and chemical reactions. Among these phenomena, sorption mechanism is described by several types of sorption isotherm. If we assume the sorption isotherm as linear, the solution of ADE can be easily procured. However, if we consider the sorption isotherm as non-linear isotherm like a Dual Reactive Domain Model (DRDM), the resulting differential equation becomes non-linear. In this case, the solution of ADE cannot be easily acquired by an analytic method. In this paper, we present the numerical analysis of ADE using a DRDM. The results reveal that even if sorption data may be fitted well using linear or non-linear isotherm, the characteristics of contaminant transport of the two cases are different from each other. To be concrete, the retardation of linear isotherm has stronger effect than that of the DRDM. As the non-linearity of sorption isotherm increases, the difference of retardation effects of the two cases becomes larger. For a pulse source, the maximum concentration of the linear model is higher than that of the DRDM, but the plume of the DRDM moves faster than that of the linear model. Behaviors of contaminant transport using the DRDM are consistent with common features of a linear model. For instance, biodegradation effect becomes larger as time goes by The faster the seepage velocity is, the faster the plume of contaminant moves. The plume of the contaminant is distributed evenly over overall domain in the event of high dispersion coefficient.

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일부 정신의료기관 정신질환자의 상태와 구강건강실태와의 관계 (The relationship between mental illness state and oral health management of mental patients in mental health care institutions)

  • 윤성욱;남인숙;전매숙
    • 한국치위생학회지
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    • 제14권4호
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    • pp.547-553
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    • 2014
  • Objectives : This research aims to analyze the relationship between the state of mental illness and oral health management of mental patients in mental health care institutions. Methods : The data were randomly selected from 474 patients in mental health care institutions. and analyzed by SPSS WIN 12.0 program. Results : Schizophrenia accounted for 79.5%(337 patients) ; alcohol dependency, 5.3%(25 patients) ; mental retardation, 2.7%(13 patients) ; mental development disorder, 3.0%(14 patients) ; mental delusion and dementia, 7.6%(36 patients). Those who were in 40s had the highest dental caries of 3.95 and the highest remaining teeth of 26.76 were shown in the 20s. The correlation between remaining teeth and mental retardation was the highest, measuring 22.38(p<.05). Those who were in 70s had the serious periodontal condition that accounted for 41.3%(12 patients)(p<.05). The correlation coefficient for all factors-dental caries, remaining teeth, need for scaling, and periodontal condition-between mental illness condition and oral health were all positive(p <.05). The regression analysis resulted in the formula Y(mental health condition)=2.999+0.166(dental aries)-0.028(remaining teeth). Conclusions : Those who had mental illness had very poor and serious dental caries and periodontal diseases, so it is necessary to manage the dental health care for the mentally ill patients.

산불로 인해 변화하는 토양지하수 환경에서의 세슘 흡착 및 거동에 대한 새로운 고찰 (A New Approach on Adsorption and Transport of Cesium in Organic Matter-rich Soil and Groundwater Environments Changed by Wildfires)

  • 배효진;정성욱;정진아
    • 한국물환경학회지
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    • 제38권1호
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    • pp.10-18
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    • 2022
  • This study was conducted to investigate the effect of soil and groundwater environment changed by wildfire on cesium adsorption and transport. Soil samples (A, B) used in the study were collected from Gangwon-do, where wildfires frequently occur, and the adsorption and transport of cesium in the samples were evaluated through batch and column experiments. As a result of the batch adsorption experiments with various concentrations of cesium (CW ≈ 10~105 ㎍/L), the adsorption distribution coefficient (Kd) of cesium was higher in sample A for all observed concentrations. It means that the adsorption capacity of sample A was higher to that of sample B, which was also confirmed through the parameters of adsorption isotherm models (Freundlich and Langmuir model) applied to the experimental results. The fixed bed column experiments simulated the actual soil and groundwater environment, and they showed that cesium was retarded approximately 43 and 27 times than a nonreactive tracer in sample A and B, respectively. In particular, a significant retardation occurred in the sample A. Although sample A contains little clays, total organic carbon (TOC) contents were 3 times greater than sample B. These results imply that particulate organic matter caused by wildfire might influence the adsorption and transport of cesium in the organic matter-rich soil and groundwater environment.

도시유역에서 저류지 설계를 위한 특성인자 분석 (An Analysis of Characteristic Parameters for the Design of Detention Pond in Urbanized Area)

  • 이재준;김호년;곽창재
    • 한국방재학회 논문집
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    • 제6권4호통권23호
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    • pp.37-47
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    • 2006
  • 도시화로 인한 유출량의 증가 및 도달시간의 단축은 도시재해의 한 원인이 되고 있다. 이를 막기 위하여 도시 배수유역내에 저류지를 설치하여 하수관거의 통수능 이하로 방류량을 조절하는 방안을 고려할 수 있다. 기초계획 단계에서의 저류지 설계를 위해서는 복잡한 연관성을 지니고 있는 제반 변수를 고려하지 않고 대표적인 관련 주요변수를 택하여 저류용량을 결정하는 여러 가지 저류지 계획모형이 이용되고 있다, 기왕의 저류지 계획모형에서는 주로 도시화 특성인자인 첨두유량비$(\alpha)$와 도달시간비$(\gamma)$를 활용하고 있다. 본 연구에서는 재해영향평가서 22개소의 저류지를 분석대상으로 하여 도시화에 따른 도시배수유역 특성인자와 저류지 특성인자간의 분석을 통해 저류지의 계획단계에서 활용할 수 있도록 편의성을 도모하고자 한다. 첨두유량비 $\alpha$가 도달시간비 $\gamma$보다 저류 용량에 미치는 영향이 더욱 민감함을 알 수 있었으며, 개발전 후의 유출계수비 $\beta$가 설계강우강도의 지역계수 n값 보다 $\alpha$에 미치는 영향이 작음을 알 수 있었다. 사다리꼴 설계수문곡선을 사용하는 경우에는 강우지속기간이 저류비에 미치는 영향이 큰 것을 알 수 있었다.

연직배수재가 설치된 정규압밀 점성토 지반의 점진적 압밀이 차후 압밀거동에 미치는 영향 (Influence of Progressive Consolidation on Consolidation Behavior of Normally Consolidated Clayey Soil with Vertical Drains)

  • 윤찬영;정충기
    • 한국지반공학회논문집
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    • 제21권6호
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    • pp.5-18
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    • 2005
  • 본 연구에서는 배수면으로부터의 거리에 따라 점진적으로 진행되는 압밀이 차후의 압밀 거동에 미치는 영향에 대하여 고찰하였다. 이를 위해 압밀진행에 따른 위치 별 투수계수 및 부피압축계수의 변화를 고려할 수 있는 유한차분 압밀해석기법 및 프로그램을 개발하였다. 개발된 해석 프로그램을 이용하여 간극비 변화에 따른 투수계수와 부피압축 켸수의 변화 정도가 다른 다양한 특성의 지반에 대하여 연직배수재가 설치된 모형지반의 압밀거동을 분석하였다. 또한 실제 지반조건에서의 영향 정도를 살펴보기 위하여, 낙동강 하구의 정규압밀 점성토 및 재성형 카올리나이트의 지반 특성을 근간으로 입력치를 결정, 해석을 수행하여 위치 별 점진적 압밀에 의한 영향을 분석하였다. 해석 결과 점진적 압밀 진행에 따른 압밀 지체가 현장의 압밀 거동 이해에 매우 중요하며, 또한 압밀 초기에, 소성성이 크고, 재하하중이 클수록 현저하게 나타남을 알 수 있었다.

Resonance analysis of cantilever porous graphene platelet reinforced pipe under external load

  • Huang, Qinghua;Yu, Xinping;Lv, Jun;Zhou, Jilie;Elvenia, Marischa Ray
    • Steel and Composite Structures
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    • 제45권3호
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    • pp.409-423
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    • 2022
  • Nowadays, there is a high demand for great structural implementation and multifunctionality with excellent mechanical properties. The porous structures reinforced by graphene platelets (GPLs) having valuable properties, such as heat resistance, lightweight, and excellent energy absorption, have been considerably used in different engineering implementations. However, stiffness of porous structures reduces significantly, due to the internal cavities, by adding GPLs into porous medium, effective mechanical properties of the porous structure considerably enhance. This paper is relating to vibration analysis of fluidconveying cantilever porous graphene platelet reinforced (GPLR) pipe with fractional viscoelastic model resting on foundations. A dynamical model of cantilever porous GPLR pipes conveying fluid and resting on a foundation is proposed, and the vibration, natural frequencies and primary resonant of such a system are explored. The pipe body is considered to be composed of GPLR viscoelastic polymeric pipe with porosity in which Halpin-Tsai scheme in conjunction with the fractional viscoelastic model is used to govern the construction relation of nanocomposite pipe. Three different porosity distributions through the pipe thickness are introduced. The harmonic concentrated force is also applied to the pipe and the excitation frequency is close to the first natural frequency. The governing equation for transverse motions of the pipe is derived by the Hamilton principle and then discretized by the Galerkin procedure. In order to obtain the frequency-response equation, the differential equation is solved with the assumption of small displacement, damping coefficient, and excitation amplitude by the multiple scale method. A parametric sensitivity analysis is carried out to reveal the influence of different parameters, such as nanocomposite pipe properties, fluid velocity and nonlinear viscoelastic foundation coefficients, on the primary resonance and linear natural frequency. Results indicate that the GPLs weight fraction porosity coefficient, fractional derivative order and the retardation time have substantial influences on the dynamic response of the system.

Nonlinear vibration analysis of fluid-conveying cantilever graphene platelet reinforced pipe

  • Bashar Mahmood Ali;Mehmet AKKAS;Aybaba HANCERLIOGULLARI;Nasrin Bohlooli
    • Steel and Composite Structures
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    • 제50권2호
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    • pp.201-216
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    • 2024
  • This paper is motivated by the lack of studies relating to vibration and nonlinear resonance of fluid-conveying cantilever porous GPLR pipes with fractional viscoelastic model resting on nonlinear foundations. A dynamical model of cantilever porous Graphene Platelet Reinforced (GPLR) pipes conveying fluid and resting on nonlinear foundation is proposed, and the vibration, natural frequencies and primary resonant of such system are explored. The pipe body is considered to be composed of GPLR viscoelastic polymeric pipe with porosity in which Halpin-Tsai scheme in conjunction with fractional viscoelastic model is used to govern the construction relation of the nanocomposite pipe. Three different porosity distributions through the pipe thickness are introduced. The harmonic concentrated force is also applied on pipe and excitation frequency is close to the first natural frequency. The governing equation for transverse motion of the pipe is derived by the Hamilton principle and then discretized by the Galerkin procedure. In order to obtain the frequency-response equation, the differential equation is solved with the assumption of small displacement, damping coefficient, and excitation amplitude by the multiple scale method. A parametric sensitivity analysis is carried out to reveal the influence of different parameters, such as nanocomposite pipe properties, fluid velocity and nonlinear viscoelastic foundation coefficients, on the primary resonance and linear natural frequency. Results indicate that the GPLs weight fraction porosity coefficient, fractional derivative order and the retardation time have substantial influences on the dynamic response of the system.

A Numerical Solution of Transport of Mono- and Tri-valent Cations during Steady Water Flow in a Binary Exchange System

  • Ro, Hee-Myong;Yoo, Sun-Ho
    • Journal of Applied Biological Chemistry
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    • 제43권1호
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    • pp.18-24
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    • 2000
  • A one-dimensional transport of displacing monovalent ion, $A^+$, and a trivalent ion being displaced, $B^{3+}^ in a porous exchange system such as soil was approximated using the Crank-Nicolson implicit finite difference technique and the Thomas algorithm in tandem. The variations in the concentration profile were investigated by varying the ion-exchange equilibrium constant (k) of ion-exchange reactions, the influent concentrations, and the cation exchange capacity (CEC) of the exchanger, under constant flux condition of pore water and dispersion coefficient. A higher value of k resulted in a greater removal of the native ion, behind the sharper advancing front of displacing ion, while the magnitude of the penetration distance of $A^+$ was not great. As the CEC increased, the equivalent fraction of $B^{3+}^ initially in the soil was greater, thus indicating that a higher CEC adsorbed trivalent cations preferentially over monovalent ions. Mass balance error from simulation results was less than 1%, indicating this model accounted for instantaneous charge balance fairly well.

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한국형 자가평가 우울척도의 개발 (Development of the Korean Form of Zung's Self-Rating Depression Scale)

  • 이중훈
    • Journal of Yeungnam Medical Science
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    • 제12권2호
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    • pp.292-305
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    • 1995
  • 우울의 존재나 정도를 양적으로 측정하고 평가하기 위한 한국형 자가평가 우울척도를 연구 개발하기 위하여 1994년 8월 부터 1995년 6월까지 검사 당시 정상적인 사회 활동에 참여하고 있는 중학교, 고등학교 및 대학교 학생 그리고 일반 성인 및 그 가족을 중심으로 남자 173명(51.8%), 여자 161명(48.2%)으로 총 334명을 대상으로 하였다. 이들에게 Zung의 자가평가 우울척도를 한국형으로 번안하여 조사 방법으로 시행하였다. 본 조사에서 수집된 자료는 종합 검토하여 불충분한 자료를 제거하고 SPSS의 프로그램을 통해서 분석하였다. 문항 분석을 시행하여 각 문항간의 상관관계 및 문항 내적 상관도를 구하여 SDS의 신뢰도를 검증한 후, SDS의 문항 구성에 대한 내용을 알아 보기 위해 요인분석을 시행하여 다음과 같은 결과를 얻었다. 전체 우울 접수의 평균은 $40.60{\pm}8.66$이였고, 전체 우울 점수의 분포는 50점 이상인 경우가 11.1%(37명)이었다. 본 척도의 신뢰도 검증에서는 검사-재검사의 신뢰도 계수는 0.82(p < .001), 항목-전체간의 상관계수의 평균치는 0.42(0.08-0.65), 내적 일관성은 0.84(p < .001)을 나타내어서 모두 통계적으로 의미있는 신뢰도를 보여주었다. 요인분석에서는 5개의 요인이 추출되었는데, 이러한 점은 우울이 여러가지 요소로 구성되어 있을 가능성도 시사한다. 우울척도에서 항목별로 높게 평가한 상위 문항들은 혼동, 우유부단, 성욕감소, 일주기성 변화 및 정신운동 지연 등의 순서이었고, 항목별 하위 문항은 자살사고의 반추, 정신운동 흥분, 변비, 과민성 및 체중감소 등의 항목이었다.

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