• The Journal of Korean Society for School & Community Health Education
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• v.21 no.1
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• pp.61-74
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• 2020

Objectives: This study aims to examine hypertension patients' quality of life by using the data of the 7^th Korea National Health and Nutrition Examination Survey (1^st year, 2016), identify the factors related to this, and utilize the results as basic data for intervention that can improve hypertension patients' quality of life. Methods: For the research subjects, this study extracted 1,531 patients who were diagnosed with hypertension by a doctor from the total sample of 8,150 participants of the 7^th Korea National Health and Nutrition Examination Survey, and selected 1,072 patients with no missing value in the variables to be analyzed as the final research subjects. The SPSS(version25.0) program was used for the analysis of the collected data. Then, this study used a backward elimination multiple regression analysis method that applied complex sample, to examine the factors related with the finally estimated quality of life. Results: The results of this study revealed that hypertension patients' quality of life was related with age, occupation, spouse, household income, weight gain, restriction of activity, subjected health status, perceived stress, and presence of comorbidity. The final model explained 37.0% of the variance (Wald F=30.012 p<.001). Conclusions: When an intervention program is implemented for the improvement of hypertension patients' quality of life in the future, it will be effective to construct the program according to age group, employment, marital status and household income. As for the program operation, patients should get help therefrom to control weight, facilitate activities and relieve their stress, and they should be also motivated to feel healthy. Furthermore, education should be offered so that they appropriately manage their underlying disease at an early stage.

• Journal of the Korean Society of School Health
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• v.15 no.1
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• pp.83-92
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• 2002

This study was undertaken to verify various relations between dental health belief and related behaviors in mothers and children. Data for this study were obtained by 264 pairs of 1st and 3rd grade elementary school children and their mothers by self developed questionnaire, The questionnaires are made on the general socio-economical characteristics, the oral health knowledge and the behaviors relative to the oral health and oral health education as to how mothers implement the oral health related activities for their children, while for the children, the questionnaires have been measured relative to the oral health beliefs and health behaviors for the children. The obtained results have shown that mothers become with more ages, the usefulness to prevent children's oral diseases becomes lower, and as much as mothers have higher education level, the sensitivity relative to the oral diseases has been measured low. To the degree that the students live well in economical respect, it has been found that they placed more importance on the oral health. As much as the number of mothers tooth brushing becomes made more in a day, the tooth brushing of the children becomes more that much, and also has higher level of oral health beliefs. The number of children to see dentists has been found high, and to the extent of increasing frequency of visiting dental clinics. As the number of mothers tooth brushing education becomes made more frequent for the children. Also, as mothers put more restriction on the sugar intakes by the children, they placed higher importance on the oral health for their children. In conclusion oral health behavior in mothers' influence on dental health belief of their children, it has been reviewed necessary to activate more the mother-children joint oral health education and oral health projects that mothers and children take part together, as well as to study more in accurate and systematic approaches through more comprehensive and various subjects and elements further in the future.

• Ocean and Polar Research
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• v.42 no.1
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• pp.33-47
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• 2020

The bulk and partition geochemistry was studied in two sediment cores collected from the axial valley of the north-central Fonualei Rift and Spreading Center (FRSC), Lau back-arc Basin, southwest Pacific. The sediments consist of mostly volcanic ash, although minor amounts of biogenic and other components were present in some intervals. The major element composition of bulk sediments recalculated to a carbonate-free basis was in good agreement with the magma compositions of the adjacent Tofua Arc and the FRSC, with only significant difference in Mn content. The enrichment of Mn and other associated elements (e.g. Cu, Co, Ni, and P) is attributed to hydrothermal input to the sediments, as evidenced by their significant partitioning in the non-detrital phases according to the partition geochemistry. Hydrogenetic and diagenetic inputs were assessed to be relatively insignificant. Estimated hydrothermal Mn fluxes during the Holocene ranged between 5.0 and 37.1 mg cm^-2 kyr^-1, with the higher values in younger sediments, suggesting enhanced hydrothermal activity. The hydrothermal Mn fluxes comparable to or higher than those reported from other spreading centers with strong hydrothermal activities may indicate the presence of unknown hydrothermal vent sites and/or topographic restriction on the dispersal of hydrothermal plumes in the northern part of the FRSC.

• Journal of Ecology and Environment
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• v.33 no.3
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• pp.261-270
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• 2010

Increasing atmospheric $CO_2$ affects the soil carbon cycle by influencing microbial activity and the carbon pool. In this study, the effects of elevated $CO_2$ on extracellular enzyme activities (EEA; ${\beta}$-glucosidase, N-acetylglucosaminidase, aminopeptidase) in salt marsh sediment vegetated with Suaeda japonica were assessed under ambient atmospheric $CO_2$ concentration (380 ppm) or elevated $CO_2$ concentration (760 ppm) conditions. Additionally, the community structure of sulfate-reducing bacteria (SRB) was analyzed via terminal restriction fragments length polymorphism (T-RFLP). Sediment with S. japonica samples were collected from the Hwangsando intertidal flat in May 2005, and placed in small pots (diameter 6 cm, height 10 cm). The pots were incubated for 60 days in a growth chamber under two different $CO_2$ concentration conditions. Sediment samples for all measurements were subdivided into two parts: surface (0-2 cm) and rhizome (4-6 cm) soils. No significant differences were detected in EEA with different $CO_2$ treatments in the surface and rhizome soils. However, the ratio of ${\beta}$-glucosidase activity to N-acetylglucosaminidase activity in rhizome soil was significantly lower (P < 0.01) at 760 ppm $CO_2$ than at 380 ppm $CO_2$, thereby suggesting that the contribution of fungi to the decomposition of soil organic matter might in some cases prove larger than that of bacteria. Community structures of SRB were separated according to different $CO_2$ treatments, suggesting that elevated $CO_2$ may affect the carbon and sulfur cycle in salt marshes.

• BMB Reports
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• v.31 no.2
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• pp.149-155
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• 1998

The N199H variant of the EcoRI endonuclease has about twice the catalytic activity of the wild-type. A comparison of their biochemical characteristics, using synthetic oligonucleotides 5'-dAAAACTTAAGAAAAAAAAAAA-3' (KA) and 5'-dTTTTTGAATTCTTTTTTTTTT-3' (KT), helps to define the cleavage reaction pathway of these enzymes. Both EcoRI and EcoRI variant N199H were found to cleave singlestranded KA or KT about three times faster than the double-stranded forms, although the KT oligonucleotide was more susceptible. Using the ssDNA substrate in kinetic analyses, lower $K_m$ values were obtained for the N199H variant than for the wild-type at low (50 mM), as well as high (200 mM), sodium chloride concentrations. This difference between the endonucleases is attributed to a grealter accessibility for tbe substrate by the variant, and also a higher affinity for the DNA backbone. It also appears that the relative activities of the two enzymes, particularly at high ionic strength, are proportional to their populations in the monomeric enzyme form. That is, according to gel filtration data, half of the N199H molecules exist as monomers in 200 mM NaCl, whereas those of the wild-type are mainly dimeric. Consequently, the Asp199 residue of the EcoRI endonuclease may be implicated in the protein-protein interaction leading to dimerization, as well as in coupling to DNA substrates. In summary, it is proposed that active monomeric endonuclease molecules, derived from the dimeric enzyme, recognize and form a complex with a single stranded form of the DNA substrate, which then undergoes nucleophilic substitution and cleavage.

• Journal of Nutrition and Health
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• v.49 no.2
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• pp.72-79
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• 2016

Purpose: The initiation of mandatory folic acid fortification using pteroylmonoglutamic acid (PteGlu) has reduced the rate of congenital malformations. However, it also appears to be responsible for several adverse effects, including increased cancer incidence. This may be related to physicho-chemical characteristics of PteGlu. This study examines the potential effect of high concentrations of PteGlu on a population subjected to mandatory folic acid fortification using an in vitro model. Methods: Caco-2 (colorectal cancer) and MCF7 (breast cancer) cell lines were cultured at 6 different PteGlu concentrations (0, 0.1, 1, 50, 250, and $500{\mu}g/ml$) for 6 days. Cell growth was determined using thiazolyl blue tetrazolium bromide assay. The genotype of dihydrofolate reductase 19bp deletion/insertion (DHFR 19-del) was also scored in cell lines using a restriction fragment length polymorphism technique to examine whether genetic variations may factor in cell proliferation. Results: PteGlu exhibited differential growth promoting properties between cell lines. Caco-2 cells did not show a significant growth difference at low concentrations compared to control, however, at higher concentrations, the growth showed a contrasting trend in the early experimental period, while MCF7 showed enhanced cell growth at all concentrations. The DHFR 19-del genotype differed in the two cell lines. Conclusions: Altered response to PteGlu by Caco-2 and MCF7 may reflect a tissue specific disease aetiology or genotype specific differential enzyme activity, for example by DHFR, to critical levels of PteGlu. As folic acid fortification is a blanket intervention, and DHFR and other enzyme activities vary between individuals, PteGlu intake may have an as yet undefined effect on health. These findings may be relevant when considering mandatory folic acid fortification for disease prevention.

• IMMUNE NETWORK
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• v.5 no.4
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• pp.252-257
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• 2005

Background: This study was designed to investigate the effect of exercise training on defense mechanism of chronic degenerative disease, aging, and memory impairments of senescence-accelerated mouse (SAM)P8 under the hypothesis that "Senile dementia may be prevented by regular exercises". Methods: To evaluate the effects of exercise training on the defense mechanism of aging and memory impairment, SAMP8 were divided into two groups, the control group and exercise training groups. the exercise training group were performed with low $(\dot{V}O_2max\;25{\sim}33%)$, middle ($\dot{V}O_2max$ 50%) and high $(\dot{V}O_2max\;66{\sim}75%)$ intensity exercise. All SAMP8 mice were fed experimental diet ad libitum until 4, 8 months, and dead period. Results: Median lifespan in middle exercise group resulted in a significantly increased (23.5% and 18.7%, respectively), whereas these lifespan in high exercise group resulted in an unexpectedly decreased (13.5% and 12.1%, respectively) compared with control group. Body fat levels in 4 and 8 months of age were significantly decreased 43% to 51% in middle exercise group, whereas were remarkably deceased to 57% in high exercise group compared with control group. It is believed that extended median and maximum lifespan may be effected by calory restriction through the exercise training. Acetylcholine (ACh) levels were significantly increased 6.7% and 8.5% in middle and high exercise groups, and also choline acetyltransfease (ChAT) activities were significantly increased 10.3% and 11.9% in middle and high exercise groups. Conclusion: These results suggest that proper and regular exercises such as middle group ($\dot{V}O_2max$ 50%) may play an effective role in attenuating an oxygen radicals and may play an important role in improving a learning and memory impairments of senile dementia.

• Human Ecology Research
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• v.57 no.2
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• pp.225-241
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• 2019

This study develops and validates an objective scale to measure newspaper use at home by elementary school students and parents. We developed a preliminary scale of 59 items through the review of literature on newspaper use and mediation as well as the examination of content validity by education experts. Collected data were analyzed using SPSS 21.0 and AMOS 21.0 programs. A total of 42 items were supported by 703 parents with students in grades 1-6 using exploratory factor analysis. The model included 3 categories and 9 sub-factors: instruction (modeling, restriction, and text instruction), activities (play activity, conversation, online mediation, and scrap activity), and belief (academic achievement and information acquisition). Confirmatory factor analysis confirmed and validated the model fit; in addition, convergent validity, and discriminant validity, and cross validity was confirmed through correlation analysis by gender comparison and grade comparison. We also verified the validity of this scale through correlation analysis based on Yu and Jung (2012)'s newspaper mediation variables and scale in regards to children's motivation for using newspapers. Finally, internal consistency reliability and half reliability were also confirmed. In conclusion, the suitability and stability of home newspaper utilization scale for elementary students (HNUS-E) were confirmed. This scale provides parents and educators with ideas for the development of the children's literacy, cognitive, and affective domains that can be effectively used in research on newspaper use for school-aged children.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.3
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• pp.215-220
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• 2018

This paper limited the participation of large corporations in the mass information market by revising the Software Industry Promotion Act in order to increase business opportunity, equality of opportunity, and capacity building for small and medium sized IT companies. However, it is a fact that the medium and small SW companies have insufficient business capacity and expose various problems such as quality degradation of public information business, inadequate risk management, and deterioration of schedule management. In order to solve this problem, this paper derived the factors of quality deterioration in the system integration project and proposed to carry out the project by using some activities of VISUALIZATION, rigorous test management and Agile Methodology as a solution. Applying these measures to healthcare IT projects developed by midsize / small-sized IT companies has improved communications, improved quantitative progress management and improved project visibility. In addition, it contributed to minimizing defect resolution time, improving the requirement coverage ratio, and shortening unnecessary meeting time.

• Korea Real Estate Review
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• v.28 no.1
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• pp.39-52
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• 2018

The purpose of this study was to analyze the housing tenure choice decisions of older households, with focus on the activity constraints of the householders. For analysis, the probit model based on the data of the householders over 55 years of age from the 2015 KLIPS data was implemented. The research findings indicate that the ownership choice probability decreases when the head of the household has activity or social activity constraints. If there is an activity restriction, it is considered that the possibility of self-residence will be low due to the increase in medical expenses, the possibility of participation in economic activities will be low, the possibility of early retirement will be high, and the income will decrease. Therefore, if the head of the household has a personal or social activity constraint, such case is more likely to be categorized as falling under the poor residential group. This result suggests that the activity constraint can be utilized as a useful index for the housing welfare policy considering physical vulnerability.