• PNF and Movement
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• v.15 no.1
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• pp.35-40
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• 2017

Purpose: The purpose of this study was to determine the immediate effects of using the proprioceptive neuromuscular facilitation (PNF) contract-relax technique in the close kinetic chain position on the gait ability and gastrocnemius muscle tone of stroke patients. Methods: The subjects were patients who had strokes due to cerebrum infarction and hemorrhage. The subjects participated in exercise with the PNF contract-relax technique in the standing-on-elbow position with a high table, and the affected lower leg was placed in the posterior position. The PNF contract-relax technique was applied at the position in which the ankle plantar-flexors were in a sufficiently elongated position. After performing twice in each range, while the muscle was elongated, the affected side was moved further back and a new range was set. In each session, the time of contraction was set to 8 seconds, and the resting time was set to 5 seconds; however, if the patient felt tired, they received more resting time during the intervention. The Myoton Pro and 10 m walking test were used to measure the muscle tone and gait ability both pre- and post-intervention. Results: After participating in the program, the muscle tone decreased and the gait ability improved in the ankle plantar-flexors, as determined by the Myoton Pro and 10 m walking test. Conclusion: The PNF contract-relax technique can help to decrease muscle tone in ankle plantar-flexors with hypertonus and increase the gait ability in stroke patients.

• Steel and Composite Structures
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• v.49 no.3
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• pp.307-323
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• 2023

In this research, the study of the thermoelastic flexural analysis of silicon carbide/Aluminum graded (FG) sandwich 2D uniform structure (plate) under harmonic sinusoidal temperature load over time is presented. The plate is modeled using a simple two dimensional integral shear deformation plate theory. The current formulation contains an integral terms whose aim is to reduce a number of variables compared to others similar solutions and therefore minimize the computation time. The transverse shear stresses vary according to parabolic distribution and vanish at the free surfaces of the structure without any use of correction factors. The external load is applied on the upper face and varying in the thickness of the plates. The structure is supposed to be composed of "three layers" and resting on nonlinear visco-Pasternak's-foundations. The governing equations of the system are deduced and solved via Hamilton's principle and general solution. The computed results are compared with those existing in the literature to validate the current formulation. The impacts of the parameters (material index, temperature exponent, geometry ratio, time, top/bottom temperature ratio, elastic foundation type, and damping coefficient) on the dynamic flexural response are studied.

• Microbiology and Biotechnology Letters
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• v.28 no.1
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• pp.33-38
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• 2000

In order to produce ascorbic acid-2-phosphate from ascorbic acid, bacteria capable of transforming ascorbic acid to ascorbic acid-2-phosphate were isolated from soils and the stock cultures in our laboratory. Among them, a newly isolated bacterium LSH-3 having the best ability of producing ascorbic acid-2-phosphate was selected and partially identified as Pseudomonas sp. The optimum conditions for the production of ascorbic acid-2-phosphate from ascorbic acid and using its resting cells as the source os enzyme were investigated. The results were summarized as follows: The optimum cultivation time and the cell weight for the production of ascorbic acid-2-phosphate was 14 hours and 100g/I(wet weight), respectively. And 0.1%(v/v) Trition X-100 was the most effective surfactant. The optimum concentrations of ascorbic acid and pyrophosphate were 400mM and 500mM, respectively, which led to produce 14.54g/I of ascorbic acid-2-phosphate. The most effective buffer was 50mM sodium acetate. The optimum pH and temperature were 4.5 and $40^{\circ}C$, respectively. Under the above conditions, 17.71 g/I of ascorbic acid-2-phosphate was produced from ascorbic acid after 32 hour-incubation, which corresponded to 17.5% of conversion rate based on ascorbic acid.

• Korean Journal of Environmental Biology
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• v.37 no.3
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• pp.268-277
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• 2019

Severe damages will result in human society, when several different critical natural phenomena coincide. One example relates to the resting cysts of Alexandrium species (dinoflagellates that cause paralytic shellfish poisoning), which are preserved in surface sediments throughout Osaka Bay, Japan. These cysts have been found to accumulate particularly densely in shallow areas in the inner parts of Osaka Bay, where a tsunami caused by an earthquake could occur any time. Damage by a tsunami could cause a change of the coastal ecosystems at Osaka Bay including the resuspension of surface sediments containing resting Alexandrium tamarense cysts and the subsequent redistribution of the cysts in newly deposited sediment. Under certain environmental conditions, these cysts could germinate and form dense blooms, leading to paralytic shellfish poisoning. Such a scenario could also affect other coastal areas, including the southern coast of the Korean Peninsula.

• Structural Engineering and Mechanics
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• v.66 no.6
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• pp.737-748
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• 2018

The current study presents a new technique in the framework of the nonlocal elasticity theory for a comprehensive buckling analysis of Euler-Bernoulli nano-beams made up of bidirectional functionally graded material (BDFGM). The mechanical properties are considered by exponential and arbitrary variations for axial and transverse directions, respectively. The various circumstances including tapering, resting on two-parameter elastic foundation, step-wise or continuous variations of axial loading, various shapes of sections with various distribution laws of mechanical properties and various boundary conditions like the multi-span beams are taken into account. As far as we know, for the first time in the current work, the buckling analyses of BDFGM nano-beams are carried out under mentioned circumstances. The critical buckling loads and mode shapes are calculated by using energy method and a new technique based on calculus of variations and collocation method. Fast convergence and excellent agreement with the known data in literature, wherever possible, presents the efficiency of proposed technique. The effects of boundary conditions, material and taper constants, foundation moduli, variable axial compression and small-scale of nano-beam on the buckling loads and mode shapes are investigated. Moreover the analytical solutions, for the simpler cases are provided in appendices.

• IMMUNE NETWORK
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• v.6 no.1
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• pp.1-5
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• 2006

Background: B cell subset has been divided into B-1 cells and B-2 cells. B-1 cells are found most prominently in the peritoneal cavity, as well as constituting a small pro portion of splenic B cells and they are larger and less dense than B-2 cells in morphology. This study was designed to compare the differences in their proliferation and differentiation between B-1 and B-2 cell. Methods: We obtained sorted B-1 cells from peritoneal fluid and B-2 cells from spleens of mice. Secreted IgM was measured by enzyme-linked immunosorbent assay. Entering of S phase in response to LPS-stimuli was measured by proliferative assay. Cell cycle analysis by propidium iodide was performed. p21 expression was assessed by real time PCR. Results: Cell proliferation and cell cycle progression in B-1 and B-2 cells, which did not occur in the absence of LPS, required LPS stimulation. After LPS stimulation, B-1 and B-2 cells were shifted to Sand G2/M phases. p21 expression by resting B-1 cells was higher than that of resting B-2 cells. Conclusion: B-1 cells differ from conventional B-2 cells in proliferation, differentiation and cell cycle.

• The Korean Journal of Physiology
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• v.28 no.1
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• pp.99-103
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• 1994

Single neuronal activities were recorded in the cuneate nucleus of awake rats during rest and running behavior. Movement-induced changes in somatic sensory transmission were tested by generating post-stimulus time histograms of these neurons' responses to stimulation through eleetrodes chronically implanted under the skin of the forepaw, during control resting behavior and during two standardized speeds of locomotor movement: slow (1.0 steps/s), fast (2.0 steps/s). The magnitudes of firing during these responses were measured and normalized as percentage increases over background firing. The averaged evoked unit responses were facilitated by $+59.3{\pm}12.5%\;and\;+25.6{\pm}5.4%$ (SEM) as compared with resting behavior, during slow and fast movement respectively. This is to be compared with the movement-induced sensory suppressions observed previously in the ventrobasal thalamus $(-31.0%{\pm}1.9%)$ and in the primary somatosensory cortex $(-71.2%{\pm}3.8%)$ of slowly running rats. These results suggest that afferent somatosensory information may be uniquely modulated at each sensory relay, such that it may be facilitated at brainstem level and then subjected to suppression at higher somatosensory nuclei during movement.

• Journal of Yeungnam Medical Science
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• v.2 no.1
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• pp.77-80
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• 1985

The R-R interval analyzer was developed to measure the autonomic nervous system function using microcomputer. The system based on 8 bit microcomputer including bandpass filter, R-wave detector and clock generator in order to obtain the mean value, standard deviation, total time, CV value, maximum value and minimum value in the specific view point of R-R interval variation. The pattern of R-R interval change after resting, voluntary standing and deep breathing can be analysed in normal subjects and diabetics with autonomic nervous dysfunction. The amplitude of the R-R interval variation showed sensitive pattern for normal subjects at resting, standing and deep breathing. On the contrary, the periodicities of amplitude for abnormal subjects with autonomic nervous dysfunction showed dull pattern. It was suggested that R-R interval analyzer is a good detection method for dysfunction of autonomic nervous system.

• Journal of Microbiology and Biotechnology
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• v.17 no.5
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• pp.769-773
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• 2007

With the aim to produce ascorbic acid-2-phosphate(AsA-2-P) from L-ascorbic acid(AsA, Vitamin C), nine bacteria conferring the ability to transform AsA to AsA-2-P were isolated from soil samples alongside known strains from culture collections. Most isolates were classified to the genus Brevundimonas by 16S phylogenetic analysis. Among them, Brevundimonas diminuta KACC 10306 was selected as the experimental strain because of its the highest productivity of AsA-2-P. The optimum set of conditions for the AsA-2-P production from AsA using resting cells as the source of the enzyme was also investigated. The optimum cultivation time was 16 h and the cell concentration was 120g/l(wet weight). The optimum concentrations of AsA and pyrophosphate were 550mM and 450mM, respectively. The most effective buffer was 50mM sodium formate. The optimum pH was 4.5 and temperature was $40^{\circ}C$. Under the above conditions, 27.5g/l of AsA-2-P was produced from AsA after 36 h of incubation, which corresponded to a 19.7% conversion efficiency based on the initial concentration of AsA.

• Earthquakes and Structures
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• v.16 no.3
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• pp.359-368
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• 2019

This paper focuses on the study of dynamic analysis of thick plates resting on Winkler foundation. The governing equation is derived from Mindlin's theory. This study is a parametric analysis of the reflections of the thickness / span ratio, the aspect ratio and the boundary conditions on the earthquake excitations are studied. In the analysis, finite element method is used for spatial integration and the Newmark-${\beta}$ method is used for the time integration. While using finite element method, a new element is used. This element is 17-noded and it's formulation is derived from using higher order displacement shape functions. C++ program is used for the analyses. Graphs are presented to help engineers in the design of thick plates subjected to earthquake excitations. It is concluded that the 17-noded finite element is used in the earthquake analysis of thick plates. It is shown that the changes in the aspect ratio are more effective than the changes in the aspect ratio. The center displacements of the reinforced concrete thick clamped plates for b/a=1, and t/a=0.2, and for b/a=2, and t/a=0.2, reached their absolute maximum values of 0.00244 mm at 3.48 s, and of 0.00444 mm at 3.48 s, respectively.