• Journal of the Earthquake Engineering Society of Korea
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• v.8 no.3
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• pp.63-76
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• 2004

This paper presents LRB-based hybrid base isolation systems employing additional active/semiactive control devices for mitigating earthquake-induced vibration of a cable-stayed 29 bridge. Hybrid base isolation systems could improve the control performance compared with the passive type-base isolation system such as LRB-installed bridge system due to multiple control devices are operating. In this paper, the additional response reduction by the two typical additional control devices, such as active type hydraulic actuators controlled by LQG algorithm and semiactive-type magnetorheological dampers controlled by clipped-optimal algorithm, have been evaluated bypreliminarily investigating the slightly modified version of the ASCE phase I benchmark cable-stayed bridge problem (i.e., the installation of LRBs to the nominal cable-stayed bridge model of the problem). It shows from the numerical simulation results that all the LRB based hybrid seismic isolation systems considered are quite effective to mitigate the structural responses. In addition, the numerical results demonstrate that the LRB based hybrid seismic isolation systems employing MR dampers have the robustness to some degree of the stiffness uncertainty of in the structure, whereas the hybrid system employing hydraulic actuators does not. Therefore, the feasibility of the hybrid base isolation systems employing semiactive additional control devices could be more appropriate in realfor full-scale civil infrastructure applications is clearly verified due to their efficacy and robustness.

• Journal of the Ergonomics Society of Korea
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• v.28 no.1
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• pp.37-51
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• 2009

The nuclear power industry in the world has recognized the importance of integrating non-technical and team skills training with the technical training given to its control room operators to reduce human errors since the Three Mile Island and Chernobyl accidents. The Nuclear power plant (NPP) industry in Korea has been also making efforts to reduce the human errors which largely have contributed to 120 nuclear reactor trips from the year 2001 to 2006. The Crew Resource Management (CRM) training was one of the efforts to reduce the human errors in the nuclear power industry. The CRM was developed as a response to new insights into the causes of aircraft accidents which followed from the introduction of flight recorders and cockpit voice recorders into modern jet aircraft. The CRM first became widely used in the commercial airline industry, but military aviation, shipboard crews, medical and surgical teams, offshore oil crews, and other high-consequence, high-risk, time-critical industry teams soon followed. This study aims to develop a CRM training program that helps to improve plant performance by reducing the number of reactor trips caused by the operators' errors in Korean NPP. The program is; firstly, based on the work we conducted to develop a human factors training from the applications to the Nuclear Power Plant; secondly, based on a number of guidelines from the current practicable literature; thirdly, focused on team skills, such as leadership, situational awareness, teamwork, and communication, which have been widely known to be critical for improving the operational performance and reducing human errors in Korean NPPs; lastly, similar to the event-based training approach that many researchers have applied in other domains: aircraft, medical operations, railroads, and offshore oilrigs. We conducted an experiment to test effectiveness of the CRM training program in a condition of simulated control room also. We found that the program made the operators' attitudes and behaviors be improved positively from the experimental results. The more implications of the finding were discussed further in detail.

• Journal of Bio-Environment Control
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• v.20 no.4
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• pp.283-289
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• 2011

This study was conducted to examine the effects of defoliation treatment on the growth and yield of strawberry ($Fragaria{\times}ananassa$ cv. Maehyang and Seolhyang) during nursery period. Leaves of strawberry plantlet had been removed except two, three and four fully expanded leaves until planting date. As the intensity of defoliation was strong, the petiole length was reduced and overgrowth of strawberry plantlet was suppressed. Outer diameter of crown in defoliation treatments significantly decreased but inner diameter of crown was not significant. Number of primary roots of the 3 leaves or 4 leaves defoliation treatment generally tended to increase, but there was not significantly different among treatments. Fresh weight and leaf area in the defoliation treatments significantly decreased and the root weight were higher in partial 3 leaves or 4 leaves defoliation treatment but was not significantly different among treatments. Because T/R ratio decreased significantly as growth inhibition of above-ground part compared to underground part, it is considered easy to take rooting after plantlet plating. As the intensity of defoliation was strong, chlorophyll contents tended to decrease significantly. Reduction of the endogenous nitrogen by defoliation effectively led to promote floral differentiation at low temperature and short day condition. This promoted timing of budding and flowering and also induced uniform flowering after plantlet planting. Marketable fruit yield of 3 leaves defoliation treatment tended to be higher than the control.

• Korean Journal of Biological Psychiatry
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• v.21 no.4
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• pp.168-174
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• 2014

Objectives Sensory gating dysfunctions in patients with schizophrenia and bipolar disorder have been investigated through two similar methods ; P50 suppression and prepulse inhibition paradigms. However, recent studies have demonstrated that the two measures are not correlated but rather constitute as distinct neural processes. Recent studies adopting spectral frequency analysis suggest that P50 suppression reflects the interaction between gamma and other frequency bands. The aim of the present study is to investigate which frequency component shows more significant interaction with gamma band. Methods A total of 108 mood disorder patients and 36 normal subjects were included in the study. The P50 responses to conditioning and test stimuli with an intra-pair interval of 500 msec were measured in the study population. According to P50 ratio (amplitude to the test stimulus/amplitude to the conditioning stimulus), the subjects with P50 ratio less than 0.2 were defined as suppressed group (SG) ; non-suppressed group (NSG) consisted of P50 ratio more than 0.8. Thirty-five and 25 subjects were included in SG and NSG, respectively. Point-to-point correlation coefficients (PPCCs) of both groups were calculated between two time-windows : the first window (S1) was defined as the time-window of one hundred millisecond after the conditioning auditory stimulus and the second window (S2) was defined as the time-window of 100 msec after the test auditory stimulus. Spectral frequency analysis was performed to investigate which frequency band results in the difference of PPCC between SG and NSG. Results Significant reduction of PPCC between S1 and S2 was observed in the SG (Pearson's r = 0.24), compared to PPCC of the NSG (r = 0.58, p < 0.05). In spectral frequency analysis, gamma band showed "phase-reset" and similar responses after the two auditory stimuli in suppressed and non-suppressed group. However in the case of alpha band, comparison showed significantly low PPCC in SG (r = -0.14) compared to NSG (r = 0.36, p < 0.05). This may be reflecting "phase-out" of alpha band against gamma band at approximately 50 msecs after the test stimulus in the SG. Conclusions Our study suggests that normal P50 suppression is caused by phase-out of alpha band against gamma band after the second auditory stimulus. Thus it is demonstrated that normal sensory gating process is constituted with attenuated alpha power, superimposed on consistent gamma response. Implications of preserved gamma and decreased alpha band in sensory gating function are discussed.

• Culinary science and hospitality research
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• v.21 no.1
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• pp.210-224
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• 2015

The purpose of this study is to identify the effects of involvement in temple food on overall satisfaction, recommendation, and revisit intention. From June 15 to August 30, 2014, for those who have participated in temple stay at four temples in South Korea, the self-administered survey was conducted. Of a total of 400 questionnaires, 289 were employed for the analyses, which accounted for 72% of response rate. Results shows that the involvement in temple food positively influenced experience driven by motivation in temple stay. Considering a particular research topic of temple stay, it implies that the involvement in temple food plays a key role in affecting emotional and social value relating to experience in temple stay. Entertaining, educational, aesthetic, deviated factors created by this experience will contribute to making special memories and feeling great enjoyment. In addition, emotional and social value by temple food have a positive effect on recommendation and revisit intention through experience satisfaction. Furthermore, experiential factor was significant to overall satisfaction, revisit and recommendation intention. Social and emotional value according to involvement in temple food, in terms of conclusions in this study, influenced a reduction of stress and improvement of enjoyment. These values relating to involvement in temple food, therefore, are assumed to be the causal relationship with experiential factor and satisfaction in temple stay and subsequently will be regarded as determinants in defining temple food as a heathy dish.

• Journal of Ginseng Research
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• v.41 no.3
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• pp.284-289
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• 2017

Background: Compound FK506 is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and inflammatory response mediated by FK506 limit its usefulness. In this study, the protective effect of Korean Red Ginseng (KRG) against FK506-induced damage in LLC-PK1 pig kidney epithelial cells was investigated. Methods: LLC-PK1 cells were exposed to FK506 with KRG and cell viability was measured. Western blotting and RT-PCR analyses evaluated protein expression of MAPKs, caspase-3, and KIM-1. TLR-4 gene expression was assessed. Caspase-3 activities were also determined. The number of apoptotic cells was measured using an image-based cytometric assay. Results: The reduction in LLC-PK1 cell viability by $60{\mu}M$ FK506 was recovered by KRG cotreatment in a dose-dependent manner. The phosphorylation of p38, p44/42 MAPKs (ERK), KIM-1, cleaved caspase-3, and TLR-4 mRNA expression was increased markedly in LLC-PK1 cells treated with $60{\mu}M$ FK506. However, with the exception of p-ERK, elevated levels of p-p38, KIM-1, cleaved caspase-3, and TLR-4 mRNA expression were significantly decreased after cotreatment with KRG. Activity level of caspase-3 was also attenuated by KRG cotreatment. Moreover, image-based cytometric assay showed that apoptotic cell death was increased by $60{\mu}M$ FK506 treatment, whereas it was decreased after cotreatment with KRG. Conclusion: Taken together, these results suggest that the molecular mechanism of KRG in the FK506-induced nephrotoxicity may lead to the development of an adjuvant for the inhibition of adverse effect FK506 in the kidney.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.1457-1460
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• 2010

최근 기후변화로 인해 태풍 등과 같은 집중성 강우가 많이 발생하고 있고, 강우시 유출 등으로 인한 유역내 발생하는 토양침식으로 인해 유역의 하천을 비롯하여 유출구에서의 탁수 및 유사 발생 문제는 우리나라 뿐만 아니라 전 세계적으로 심각한 환경문제로 대두되고 있다. 강우시 유역에서 발생하는 이러한 탁수문제를 효과적으로 해결하기 위하여 여러 최적관리기법 (Best Management Practices, BMPs) 들이 제안되어왔다. 본 연구의 목적은 볏짚매트 사용으로 인한 토양유실 저감 실측자료를 바탕으로 볏짚매트를 다양한 경사지 밭에 적용하였을 경우 유역에서의 토양유실 저감효과를 평가하기 위한 모델링 기법을 개발하는데 있다. 볏짚 매트의 효과를 Soil and Water Assessment Tool (SWAT) 모형으로 모의하기 위해서는 볏짚매트의 효과를 모형에서 반영할 수 있는 인자를 선택하여 최적의 인자값을 산정해야 한다. 본 연구에서는 유사 저감 효과 실험 결과를 VFSMOD-W 모형을 이용하여 USLE P 인자값을 도출하였으며, 경사도에 따른 USLE-P 값을 산정하여, SWAT 모형에 입력자료로 사용하였다. 분포형 모형과는 달리 준분포형 모형인 SWAT 모형은 소유역내 수문학적 반응단위별로 유출, 유사, 그리고 비점오염 발생을 평가하는데 이때 Hydrologic Response Unit (HRU)의 지형정보가 활용된다. 이 지형정보는 SWAT 유사 평가시 매우 민감한 변수중의 하나이기 때문에 유역 단위 유사 평가시 정확한 지형자료의 입력이 요구된다. 그러나 SWAT 모형은 소유역내 HRU의 경사도 및 경사장을 직접 산정하지 않고, 소유역의 평균경사도를 기준으로 하여 산정된 경사도를 소유역내 모든 HRU에 동일하게 적용하는 단점이 있다. 본 연구에서는 준분포 모형인 SWAT 모형의 단점을 개선하기 위하여 SWAT Spatially Distributed (SD)-HRU를 적용하였다. 이를 통해 다양한 경사지 밭에서의 볏짚매트의 효과를 분석할 수 있게 되었다. 볏짚매트 미적용시 모의 기간내 유사량 총합은 74,954.42 ton 이고, 월평균 유사량은 814.72 ton 으로 산정되었고, 볏짚매트를 적용하였을 경우 모의 기간내 (2000년 1월 - 2007년 8월) 유사량 총합은 48,460.55 ton 이고, 월평균 유사량은 526.75 ton 으로 볏짚매트를 적용하지 않았을 때보다 약 35.35 % 저감된 값을 보였다. SD-HRU를 적용하고 각 농경지의 경사도에 따라 USLE P 값을 수정하여 볏짚매트에 의한 효과를 분석하였을 때, 볏짚매트를 적용하지 않았을 때 보다 볏짚매트를 적용하였을 때 모의 기간내 약 35% 정도의 유사량이 감소된 것을 알 수 있었다. 본 연구결과에서 보여주는 바와 같이 고랭지 지역에서의 영농활동 시 볏짚매트를 설치한다면 강우시 발생하는 토양유실을 효과적으로 저감시킬 수 있을 것이라 판단된다.

• Journal of Life Science
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• v.23 no.12
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• pp.1495-1500
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• 2013

The objective of this study was to evaluate the anti-melanogenic effects of Hizikia fusiforme (HF) fractions in ${\alpha}$-melanocyte stimulating hormone-induced B16F10 mouse melanoma cells. Ethanol extractions of Hizikia fusiforme (EEHF) were subjected to fraction by using dichloromethane (CFHF), ethyl acetate (EAFHF), butanol (BFHF), and water (WFHF). EEHF, CFHF, and EAFHF inhibited tyrosinase activity and melanin synthesis in B16F10 mouse melanoma cells in a dose-dependent manner. The melanin contents were inhibited by 40.5% and 33.2% in response to treatment with 50 ${\mu}g/ml$ of EEHF and CFHF, respectively. In addition, tyrosinase activities showed a 53.3% and 54.1% reduction in treatment with 50 ${\mu}g/ml$ of EEHF and CFHF. Western blotting analysis showed that EEHF, CFHF, and EAFHF inhibited tyrosinase, TRP-1, TRP-2, and MITF expression in a dose-dependent manner. In conclusion, these findings indicate that ethanol and dichloromethane fractions of Hizikia fusiforme, which inhibit melanin synthesis and tyrosinase activity, are effective skin-whitening agents.

• The Korean Journal of Mycology
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• v.11 no.4
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• pp.169-175
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• 1983

For the classification of 531 isolates of Fusarium moniliforme from infected rice plants, five criteria were employed for clarifying the mycological difference from I to IV based on host symptoms, conidial formation, septate of macroconidia, color of mycelium on the culture, and fungicide response. Four strains I, II, III, and IV were detected and Strain IV was the most prevalent one. Based on mycological characteristics, macroconidia with 6 or 7 septate were mostly produced by Strains I and II. Four septate macroconidia were mostly formed by Strain III while Strain IV mostly formed 3 septate macroconidia. Strain I was reddish purple (5RP 5/4) on both the bottom and the surface of the media. Strain II produced reddish purple(5RP 3/2) on both the bottom and the surface of the media. Strain I produced mostly macroconidia in pionnotes on the media surface while Strain II produced mostly microconidia in pionnotes on the media surface. Both of Strain III and IV produced mostly macroconidia in sporodochia on the surface of the mycelium. Strain IV was less reduction of germination and caused abnormal elongation of all parts of the plants, but did not kill the plants in nursery boxes. Strain III killed fewer plants than Strain IV. As above results, isolates of F. moniliforme were classified into four strains I, II, III, and IV, on the basis of five criteria.

• Korean Journal of Medicinal Crop Science
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• v.11 no.1
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• pp.31-39
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• 2003

The antioxidative activities and biological properties in the EtOAc extracts and purified extracts of Orostachys japonicus were measured by assay of DPPH, xanthine/xanthine oxidase and mammalian cells(2-12). Scavenging of DPPH radical and inhibition of xanthine/xanthine oxidase of EtOAc extracts were showed the highest activity in the arable land and in September. The S-4 fraction showed the highest activity among the silica-gel column chromatography fractions. LH-4 fraction showed higher activity than the other fractionsins in assay of DPPH and xanthine/xanthine oxidase. Fatty acids and phenolic compounds were identified by GC/MS and main compounds were 1,2,3-benzenetriol, alpha-androsta-7,14-diene in LH-4 fraction. The activities of POD and SOD in samples havested on different habitats were high such as arable land> intermountain> seashore. That of POD and SOD in crude extracts of late stage were higher than early stage. Isozyme bands of crude extracts samplinged in all habitats and all growing stages showed two bands and the signal intensity showed strongly according to passage of growing stage. The purified extracts of LH-4 fraction showed excellent inhibition effect in proliferation of HL-60 cells and markedly suppressed colony formation in mouse fibroblast cells. Dose response between partially purified extracts(400ppm) and negative control did not produced statistically significant reduction in colony formation.