• Journal of Mechanical Science and Technology
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• v.18 no.1
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• pp.37-44
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• 2004

This paper presents an approach to optimally design the air bearing surface (ABS) of the head slider by using the approximation methods. The reduced basis concept is used to reduce the number of design variables. In the numerical calculation, the progressive quadratic response surface modeling (PQRSM) is used to handle the non-smooth and discontinuous cost function. A multi-criteria optimization problem is formulated to enhance the flying performances over the entire recording band during the steady state and track seek operations. The optimal solutions of the sliders, whose target flying heights are 12 nm and 9 nm, are automatically obtained. The flying heights during the steady state operation become closer to the target values and the flying height variations during the track seek operation are smaller than those for the initial one. The pitch and roll angles are also kept within suitable ranges over the recording band.

• Journal of the Korea Fashion and Costume Design Association
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• v.23 no.3
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• pp.43-55
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• 2021

Unlike nail care, nail art is a field with strong decorative elements that decorate the surface of the nail. In line with the trend of the times, which freely expresses one's personality, nail art is establishing itself as a definite and a key area in the beauty industry. Currently, design creation and technology developments are important, with the release of various nail materials and new trends that spread through mass media. Despite the great developments in the nail beauty industry, there is a lack for nail artists. Due to this fact, it is considered a necessary to combine nail art with the contemporary art styles, which have various motifs of design, and to study nail art design using them. In response, this study selected art from the Rococo era, where delicate and colorful decorative elements were at their peak, to consider the artistic styles of the time and present them in various nail designs. This study would like to expand the scope of new nail designs by suggesting colorful and feminine designs to women, who are the main customers of nail salon. In addition, the purpose of this study is to provide nail artists with basic materials that can be used in creative ideas and expressions, such as 2D and 3D nail designs, and composite nail design art, which are the art areas for nail art.

• Food Science of Animal Resources
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• v.30 no.1
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• pp.66-72
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• 2010

Pediococcus pentosaceus SA131 was isolated from jeotgal, is the bacteriocin producer against bovine mastitis pathogens, Streptococcus uberis E290, Enterococcus gallinarum E362, and Staphylococcus epidermidis ATCC 12228. The medium composition for pediocin SA131 production by P. pentosaceus SA131 was optimized using response surface methodology. Component of medium was studied as carbon source (glucose, fructose, lactose, glycerol, sucrose, maltose, and mannitol), nitrogen source (beef extract, yeast extract, peptone, malt extract, and tryptone), mineral and surfactant ($MgSO_4$, $KH_2PO_4$, $(NH_4)_2SO_4$, $MnSO_4$, NaCl, sodium acetate, and Tween 80). Through one factor-at-a-time experiment, glucose, fructose, yeast extract, malt extract, NaCl, $MgSO_4$, and Tween 80 were determined as the good ingredient. The effects of major factors for pediocin SA131 production were investigated by two-level fractional factorial designs (FFD). By a $2^4$ FFD, fructose, yeast extract, and $MnSO_4$ were found to be the important factors for the bacteriocin production. Subsequently, a $2^3$ central composite design (CCD) was adopted to derive a statistical model for optimizing the composition of the fermentation medium. The estimated optimum composition for the production of pediocin SA131 by P. pentosaceus SA131 was as follows; 0.13% fructose, 1% glucose, 1.8% yeast extract, 2.58% $MnSO_4$, 0.2% NaCl, and 0.2% Tween 80. The pediocin production under optimized medium was increased to 1,000 AU/mL, compared to the 400 AU/mL in MRS medium.

• The Korean Journal of Applied Statistics
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• v.15 no.2
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• pp.395-403
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• 2002

In the third phase of the response surface methods, the first-order model is assumed and the curvature of the response surface is checked with a fractional factorial design augmented by centre runs. We further assume that a true model is a quadratic polynomial. To choose an optimal design, Box and Draper(1959) suggested the use of an average mean squared error (AMSE), an average of MSE of y(x) over the region of interest R. The AMSE can be partitioned into the average prediction variance (APV) and average squared bias (ASB). Since AMSE is a function of design moments, region moments and a standardized vector of parameters, it is not possible to select the design that minimizes AMSE. As a practical alternative, Box and Draper(1959) proposed minimum bias design which minimize ASB and showed that factorial design points are shrunk toward the origin for a minimum bias design. In this paper we propose a robust AMSE design which maximizes the minimum efficiency of the design with respect to a standardized vector of parameters.

• Journal of Microbiology and Biotechnology
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• v.19 no.4
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• pp.378-386
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• 2009

A sequential optimization strategy, based on statistical experimental designs, is employed to enhance the production of alkaline protease by a Bacillus pseudofirmus local isolate. To screen the bioprocess parameters significantly influencing the alkaline protease activity, a 2-level Plackett-Burman design was applied. Among 15 variables tested, the pH, peptone, and incubation time were selected based on their high positive significant effect on the protease activity. A near-optimum medium formulation was then obtained that increased the protease yield by more than 5-fold. Thereafter, the response surface methodology(RSM) was adopted to acquire the best process conditions among the selected variables, where a 3-level Box-Behnken design was utilized to create a polynomial quadratic model correlating the relationship between the three variables and the protease activity. The optimal combination of the major medium constituents for alkaline protease production, evaluated using the nonlinear optimization algorithm of EXCEL-Solver, was as follows: pH of 9.5, 2% peptone, and incubation time of 60 h. The predicted optimum alkaline protease activity was 3,213 U/ml/min, which was 6.4 times the activity with the basal medium.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.24 no.3
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• pp.308-313
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• 2015

In this research, a multi-objective optimal design of a scroll compressor lower frame was approximated, and the design parameters of the lower frame were selected. The sensitivity of the design parameters was induced through a parameter analysis, and the thickness was determined to be the most sensitive parameter to stress and deflection. All of the design parameters regarding the mass are sensitive factors. It was formulated for the problem about stress and deflection to be caused by the axial load. The sensitivity of the design variables was determined using an orthogonal array for the parameter analysis. Using the central composite and D-optimal designs, a second polynomial approximation of the objective and constraint functions was formulated and the accuracy was verified through an R-square. These functions were applied to the optimal design program (NSGA-II). Through a CAE analysis, the effectiveness of the central composite and D-optimal designs was determined.

• Structural Engineering and Mechanics
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• v.55 no.5
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• pp.979-999
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• 2015

This paper proposes a novel reliability analysis method which computes reliability index, most probable point and probability of failure of uncertain systems more efficiently and accurately with compared to Monte Carlo, first-order reliability and response surface methods. It consists of Initial and Simulation steps. In Initial step, a number of space-filling designs are selected throughout the variables space, and then in Simulation step, performances of most of samples are estimated via interpolation using the space-filling designs, and only for a small number of the samples actual performance function is used for evaluation. In better words, doing so, we use a simple interpolation function called "reduced" function instead of the actual expensive-to-evaluate performance function of the system to evaluate most of samples. By using such a reduced function, total number of evaluations of actual performance is significantly reduced; hence, the method can be called Reduced Function Evaluations method. Reliabilities of six examples including series and parallel systems with multiple failure modes with truncated and/or non-truncated random variables are analyzed to demonstrate efficiency, accuracy and robustness of proposed method. In addition, a reliability-based design optimization algorithm is proposed and an example is solved to show its good performance.

• Journal of Microbiology and Biotechnology
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• v.17 no.12
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• pp.1930-1936
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• 2007

A sequential optimization strategy based on statistical experimental designs was employed to enhance the production of cyclosporin A (CyA) by Tolypocladium inflatum DSMZ 915 in a submerged culture. A 2-level Plackett-Burman design was used to screen the bioprocess parameters significantly influencing CyA production. Among the 11 variables tested, sucrose, ammonium sulfate, and soluble starch were selected, owing to their significant positive effect on CyA production. A response surface methodology (RSM) involving a 3-level Box-Behnken design was adopted to acquire the best process conditions. Thus, a polynomial model was created to correlate the relationship between the three variables and the CyA yield, and the optimal combination of the major media constituents for cyclosporin A production, evaluated using the nonlinear optimization algorithm of EXCEL-Solver, was as follows (g/l): sucrose, 20; starch, 20; and ammonium sulfate, 10. The predicted optimum CyA yield was 113 mg/l, which was 2-fold the amount obtained with the basal medium. Experimental verification of the predicted model resulted in a CyA yield of 110 mg/l, representing 97% of the theoretically calculated yield.

• Resources Recycling
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• v.21 no.3
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• pp.39-47
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• 2012

This study was conducted to optimize a mixing design of lightweight aerated concrete with the blast furnace slag(BFS) using Box-Behnken method, one of response surface designs. The lightweight aerated concrete with the BFS was made on the conditions of steam curing method at atmospheric pressure. The experimental factors were unit Water(W)/total powder($P_d$) ratio, BFS replacement percentage and Al powder addition based on the total powder (${P_d}^*$%). From the results of the response surface analysis, regression models for dried specific gravity and compressive strength of the lightweight aerated concrete were derived. When the target values for dried specific gravity and compressive strength of the lightweight aerated concrete were set at 0.72 and 4.42 MPa respectively, its optimized mixing conditions driven from the regression models were 0.62 of $W/P_d$ ratio, 35.5% of BFS replacement and 0.05% of Al powder addition. This experimental design model was found to be credible by measuring the dried specific gravity and compressive strength of the sample made from the above mixing conditions.

• Journal of the Korea Safety Management & Science
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• v.21 no.1
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• pp.17-23
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• 2019

The diesel engine generate many pollutants such as PM(Particulate matter) and NOx(Nitrogen oxide). So the SCR(Selective catalytic reduction) must be required to meet the emission standard. The SCR catalyst market is growing rapidly, and the automobile markets using alternative energy sources are growing rapidly. This study deals with optimization of the calcination process the manufacturing process of SCR catalyst to be competitive. The calcination process is a bottleneck and it is required to optimize productivity and accept to be safety, But we cannot trade off anything in terms of safety. We applied DOE(Design of experiments) among many research methods performed in various fields. In order to achieve quality and productivity optimization. The dependent variables in the DOE were selected as NO Conversion(%). The independent variables were selected as the calcination temperature, soaking time and fan speed RPM. the CCD(Central composite designs) constructs response surface using the data onto experience and finds optimum levels within the fitted response surfaces. Our tests are our stability guarantee and efficient together with operation.