• Title/Summary/Keyword: Response Surface Analyzing Method

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Toxicological Assessment to Environmental Stressors Using Exoskeleton Surface Roughness in Macrophthalmus japonicus: New Approach for an Integrated End-point Development (칠게 외골격 표면 거칠기를 이용한 노출 독성 평가: 새로운 융합적 연구)

  • Park, Kiyun;Kwak, Ihn-Sil
    • Korean Journal of Ecology and Environment
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    • v.54 no.4
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    • pp.265-271
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    • 2021
  • Intertidal mud crab (Macrophthalmus japonicus) is an organism with a hard chitinous exoskeleton and has function for an osmotic control in response to the salinity gradient of seawater. Crustacean exoskeletons change in their natural state in response to environmental factors, such as changes in the pH and water temperature, and the presence of pollutant substances and pathogen infection. In this study, the ecotoxicological effects of irgarol exposure and heavy metal distribution were presented by analyzing the surface roughness of the crab exoskeleton. The exoskeleton surface roughness and variation reduced in M. japonicus exposed to irgarol. In addition, it was confirmed that the surface roughness and variation were changed in the field M. japonicus crab according to the distribution of toxic heavy metals(Cd, Pb, Hg) in marine sediments. This change in the surface roughness of the exoskeleton represents a new end-point of the biological response of the crab according to external environmental stressors. This suggests that it may affect the functional aspects of exoskeleton protection, support, and transport. This approach can be utilized as a useful method for monitoring the aquatic environment as an integrated technology of mechanical engineering and biology.

Application of Response Surface Methodology for Optimization of Applemango Jelly Processing (애플망고 젤리의 제조 최적화를 위한 반응표면분석법의 적용)

  • Hyeonbin, Oh;Hyun-Jeong, Shim;Chae-wan, Baek;Hyun-Wook, Jang;Young, Hwang;Yong Sik, Cho
    • The Korean Journal of Food And Nutrition
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    • v.35 no.6
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    • pp.473-480
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    • 2022
  • This study aimed to develop an optimal processing method for the production of apple-mango jelly for domestic suppliers, by analyzing the quality attributes of the jelly. According to the central composite design, a total of 11 experimental points were designed including the content of apple-mango juice (X1), and the sugar content (X2). The responses were analyzed including the color values (CIE Lab and color difference), physicochemical properties (water activity, sweetness, pH, and total acidity), and textural properties (hardness and gel strength). Regression analysis was conducted, except for total acidity, and showed no significant difference for all the experimental points (p<0.05). Quadratic model was derived for all responses with an R square value ranging from 0.8590 to 0.9978. Based on regression model, the appropriate mixing ratio of apple-mango jelly was found to be 31.11% of apple mango juice and 14.65% of sugar. Through this study, the possibility for developing jelly product using apple-mango was confirmed, and it is expected that these findings will contribute to the improvement of the agricultural industry.

Determination of nickel and cadmium in fish, canned tuna, black tea, and human urine samples after extraction by a novel quinoline thioacetamide functionalized magnetite/graphene oxide nanocomposite

  • Naghibzadeh, Leila;Manoochehri, Mahboobeh
    • Carbon letters
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    • v.26
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    • pp.43-50
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    • 2018
  • In this research, a novel and efficient quinoline thioacetamide functionalized magnetic graphene oxide composite ($GO@Fe_3O_4@QTA$) was synthesized and utilized for dispersive magnetic solid phase preconcentration of Cd(II) and Ni(II) ions in urine and various food samples. A number of diverse methods were employed for characterization of the new nanosorbent. The design of experiments approach and response surface methodology were applied to monitor and find the parameters that affect the extraction performance. After sorption and elution steps, the concentrations of target analytes were measured by employing FAAS. The highest extraction performance was achieved under the following experimental conditions: pH, 5.8; sorption time, 6.0 min; $GO@Fe_3O_4@QTA$ amount, 17 mg; 2.4 mL $1.1mol\;L^{-l}$ $HNO_3$ solution as the eluent and elution time, 13.0 min. The detection limit is 0.02 and $0.2ng\;mL^{-1}$ for Cd(II), and Ni(II) ions, respectively. The accuracy of the new method was investigated by analyzing two certified reference materials (sea food mix, Seronorm LOT NO 2525 urine powder). The interfering study revealed that there are no interferences from commonly occurring ions on the extractability of target ions. Finally, the new method was satisfactorily employed for rapid extraction and determination of target ions in urine and various food samples.

Partial safety factors for retaining walls and slopes: A reliability based approach

  • GuhaRay, Anasua;Baidya, Dilip Kumar
    • Geomechanics and Engineering
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    • v.6 no.2
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    • pp.99-115
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    • 2014
  • Uncertainties in design variables and design equations have a significant impact on the safety of geotechnical structures like retaining walls and slopes. This paper presents a possible framework for obtaining the partial safety factors based on reliability approach for different random variables affecting the stability of a reinforced concrete cantilever retaining wall and a slope under static loading conditions. Reliability analysis is carried out by Mean First Order Second Moment Method, Point Estimate Method, Monte Carlo Simulation and Response Surface Methodology. A target reliability index ${\beta}$ = 3 is set and partial safety factors for each random variable are calculated based on different coefficient of variations of the random variables. The study shows that although deterministic analysis reveals a safety factor greater than 1.5 which is considered to be safe in conventional approach, reliability analysis indicates quite high failure probability due to variation of soil properties. The results also reveal that a higher factor of safety is required for internal friction angle ${\varphi}$, while almost negligible values of safety factors are required for soil unit weight ${\gamma}$ in case of cantilever retaining wall and soil unit weight ${\gamma}$ and cohesion c in case of slope. Importance of partial safety factors is shown by analyzing two simple geotechnical structures. However, it can be applied for any complex system to achieve economization.

Evaluation of excavation damage zone during TBM excavation - A large deformation FE analysis study (TBM 굴착으로 인한 굴착손상영역 범위 추정 - 대변형 수치해석 연구)

  • Seheon Kim;Dohyun Kim
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.26 no.1
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    • pp.1-17
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    • 2024
  • Analyzing the tunnel excavation behavior and its effect on the surrounding ground involves large deformation behavior. Therefore, in order to properly simulate the tunnel excavation process and rigorously investigate the actual effect of excavation on surrounding ground and tunnel structure large deformation analysis method is required. In this study, two major numerical approaches capable of considering large deformations behavior were applied to investigate the effect of tunnel boring machine excavation on the surrounding ground: coupled Eulerian-Lagrangian (CEL) and the automatic remeshing (AR) method. Relative performance of both approaches was evaluated through the ground response due to TBM excavation. The ground response will be quantified by estimating the range of the excavation damaged zone (EDZ). By comparing the results, the range of the EDZ will be suggested on the vertical and horizontal direction along the TBM excavation surface. Based on the computed results, it was found that the size of EDZ around the excavation surface and the tendencies was in good agreement among the two approaches. Numerical results clearly show that the size of the EDZ around the tunnel tends to be larger for rock with higher RMR rating. The size of the EDZ is found to be direct proportional to the tunnel diameter, whereas the depth of the tunnel is inversely proportional due to higher confinement stress around the excavation surface.

Efficiency of Dynamic Mesh in Static Aeroelastic Analysis and Design Optimization Problem (정적 공탄성 해석과 최적화 문제에서의 동적 격자의 효용성)

  • Kim, Byung-Kon;Jun, Sang-Ook;Jeon, Yong-Hee;Kim, Jeong-Hwa;Lee, Dong-Ho
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.35 no.2
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    • pp.87-93
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    • 2007
  • Generally, the analysis using Computational Fluid Dynamics(CFD) is necessary for aircraft design. However, the analysis using CFD, it requires a lot of computational time and cost. But we can reduce grid reconstruction time of analyzing the various models if we use dynamic mesh. In addition, dynamic mesh can be an efficient technique in aeroelastic analysis and design optimization problem because these problems need grid reconstruction process frequently.

Analyzing Effective Factors on Hydrogen Release Based on Response Surface Method and Analysis of Variance (반응표면법과 ANOVA 기반의 수소 누출에 대한 유효인자 분석)

  • JUNSEO LEE;SEHYEON OH;SEUNGHYO AN;EUNHEE KIM;BYUNGCHOL MA
    • Transactions of the Korean hydrogen and new energy society
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    • v.34 no.6
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    • pp.712-721
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    • 2023
  • While hydrogen is widely used, it has a low minimum ignition energy, raising safety concerns when using it. This research studied which parameters are the key variables in the hydrogen release and diffusion. These parameters were divided into six process variables in the initial release and two environmental variables in the dispersion. One hundred and twenty cases were selected through design of experiment, and the end-point in each case were analyzed using PHAST. Afterwards, an end-point prediction model was developed using RSM and ANOVA, and the impact of each variable on the endpoint was analyzed. As a result, the influence of eight variables was graded. The nozzle diameter had the greatest influence on the end-point, while the pipe roughness coefficient had no effect on the end-point. It is expected that these results will be used as basic data to improve safety across all fields of hydrogen handling facilities.

A novel coupled finite element method for hydroelastic analysis of FG-CNTRC floating plates under moving loads

  • Nguyen, Vu X.;Lieu, Qui X.;Le, Tuan A.;Nguyen, Thao D.;Suzuki, Takayuki;Luong, Van Hai
    • Steel and Composite Structures
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    • v.42 no.2
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    • pp.243-256
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    • 2022
  • A coupled finite element method (FEM)-boundary element method (BEM) for analyzing the hydroelastic response of functionally graded carbon nanotube-reinforced composite (FG-CNTRC) floating plates under moving loads is firstly introduced in this article. For that aim, the plate displacement field is described utilizing a generalized shear deformation theory (GSDT)-based FEM, meanwhile the linear water-wave theory (LWWT)-relied BEM is employed for the fluid hydrodynamic modeling. Both computational domains of the plate and fluid are coincidentally discretized into 4-node Hermite elements. Accordingly, the C1-continuous plate element model can be simply captured owing to the inherent feature of third-order Hermite polynomials. In addition, this model is also completely free from shear correction factors, although the shear deformation effects are still taken into account. While the fluid BEM can easily handle the free surface with a lower computational effort due to its boundary integral performance. Material properties through the plate thickness follow four specific CNT distributions. Outcomes gained by the present FEM-BEM are compared with those of previously released papers including analytical solutions and experimental data to validate its reliability. In addition, the influences of CNT volume fraction, different CNT configurations, water depth, and load speed on the hydroelastic behavior of FG-CNTRC plates are also examined.

A Study of Symmetry in the Patterns of Muscle Coordination and Interjoint Coordination in the Upper Limb Activity Among Subjects With Stroke (뇌졸중 환자의 상지에서 근육협응 패턴과 관절협응 패턴의 유사성에 관한 연구)

  • Lee, Jung-Ah;Shin, Hwa-Kyung;Chung, Yi-Jung;Cho, Sang-Hyun
    • Physical Therapy Korea
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    • v.13 no.1
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    • pp.54-60
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    • 2006
  • This study aimed to compare movement patterns of shoulder joints between the right and left symmetry in stroke patients and control subjects. This study proposes use of the voluntary response index (VRI) calculated from quantitative analysis of surface electromyographic (sEMG) and motion data recorded during voluntary movement as a feeding task. The VRI is comprised of two numeric values, one derived from the total muscle activity recorded for the voluntary motor task (magnitude), and the other from the sEMG distribution across the recorded muscles with the similarity index (SI). Five stroke patients and five age-matched healthy controls were recruited. Feeding motion was performed using the provided spoon five times with rests taken on a chair in between tasks. EMG data were digitized and analyzed on the basis of the root mean square (RMS) envelope of activity. The average amplitude of responses was calculated. Responsiveness and clinically meaningful levels of discrimination between stroke patients and control for EMG magnitude and SI were determined. The similarity index of the results from two successive examinations of both sides apart for stroke patients and control subjects were .86 and .95 in motion analysis and .84 and .99 in electromyographic analysis. The SI of sEMG data and motion data was significantly correlated in stroke patients. The data suggest that SI is a sensitive program for comparing and analyzing the symmetry of muscle activity and motion in both sides. This analysis method has a clinical value in grading muscular activity and movement impairment after brain injury.

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Box-Wilson Experimental Design-based Optimal Design Method of High Strength Self Compacting Concrete (Box-willson 실험계획법 기반 고강도 자기충전형 콘크리트의 최적설계방법)

  • Do, Jeong-Yun;Kim, Doo-Kie
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.5
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    • pp.92-103
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    • 2015
  • Box-Wilson experimental design method, known as central composite design, is the design of any information-gathering exercises where variation is present. This method was devised to gather as much data as possible in spite of the low design cost. This method was employed to model the effect of mixing factors on several performances of 60 MPa high strength self compacting concrete and to numerically calculate the optimal mix proportion. The nonlinear relations between factors and responses of HSSCC were approximated in the form of second order polynomial equation. In order to characterize five performances like compressive strength, passing ability, segregation resistance, manufacturing cost and density depending on five factors like water-binder ratio, cement content, fine aggregate percentage, fly ash content and superplasticizer content, the experiments were made at the total 52 experimental points composed of 32 factorial points, 10 axial points and 10 center points. The study results showed that Box-Wilson experimental design was really effective in designing the experiments and analyzing the relation between factor and response.