While the influence of healthcare accreditation system to the quality improvement of hospitals has more increased, regarding the preparation costs for healthcare accreditation, it has never been empirically studied about the costs that are actually invested by hospitals. This study is going to determine the difficulties in the preparation process of accreditation and details of accreditation preparation costs for hospitals that participated in the healthcare accreditation system and acquired accreditation. The survey was performed in a self-reported form from February 28 to March 21 2014 for 189 acute hospitals accredited as a hospital from 2011 to February 2014. Of all questionaries of survey participants, 98 were recovered; the response rate was 51.9%. A total of 40 questionnaires were used except for 58 containing insincere answers. Main findings are followings: Firstly, findings showed that advanced general hospitals spent the most statistically significantly highest in terms of equipments and total costs among cost items for accreditation preparation. When accreditation preparation costs items were classified according to classification of hospitals, advanced general hospitals spent the most statistically significantly highest in the equipments and total costs. Also in terms of regional, Gyeonggi, Incheon regions were found to spend statistically significantly higher costs in the equipments costs. Secondly, as a result of the survey in the distribution of the total accreditation preparation costs, advanced general hospitals have disbursed the most out of all. However, the result in hospitals does not show significant difference to the expense of advanced general hospitals and that especially other regional hospitals spent higher costs. As such, all hospitals are under a heavy burden of higher costs on accreditation preparation, especially hospitals. The build-up of infrastructures by hospitals through an accreditation system consequently led to a higher initial investment; if the accreditation system is effective in improving the quality of health care and patient safety, appropriate responses are needed. In other words, financial support for investment costs needs to be given to allow hospitals to actively participate in the accreditation system.
Korean Journal of Construction Engineering and Management
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v.14
no.4
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pp.97-107
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2013
Occupational safety and health management expense in construction industry means the monetary amount that the purchaser appropriates to prevent various disaster from happening during the construction period by setting aside a certain amount from subcontract based on the construction type and scale. The current appropriation standard of the Ministry of Employment and Labor has been enforced since its stipulation in 1988 although various policy changes for the safety in construction industry, e.g. the development of occupational safety management techniques in construction industry, changes in construction field site environment, cost depreciation, etc., are happening in Korea and overseas. Therefore, it is required at this point to examine whether the current occupational safety and health management expense appropriation is proper or not on the basis of time trend and the changes in the construction industry environment. Accordingly, this study aims at investigating the appropriation of occupational safety and health management expense for construction industry by the construction type and target expense in response to current construction industry environment and proposing the proper appropriation. The above research result proposes the calibration of the appropriation as specified and stipulated by the Ministry of Employment and Labor by the construction type and target expense, which is necessary to reflect the actual condition of the current construction industry environment.
Oh, Jaeseong;Yi, Sojeong;Gu, Namyi;Shin, Dongseong;Yu, Kyung-Sang;Yoon, Seo Hyun;Cho, Joo-Youn;Jang, In-Jin
Genomics & Informatics
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v.16
no.3
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pp.52-58
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2018
In this report, we present a case study of how pharmacogenomics and pharmacometabolomics can be useful to characterize safety and pharmacokinetic profiles in early phase new drug development clinical trials. During conducting a first-in-human trial for a new molecular entity, we were able to determine the mechanism of dichotomized variability in plasma drug concentrations, which appeared closely related to adverse drug reactions (ADRs) through integrated omics analysis. The pharmacogenomics screening was performed from whole blood samples using the Affymetrix DMET (Drug-Metabolizing Enzymes and Transporters) Plus microarray, and confirmation of genetic variants was performed using real-time polymerase chain reaction. Metabolomics profiling was performed from plasma samples using liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. A GSTM1 null polymorphism was identified in pharmacogenomics test and the drug concentrations was higher in GSTM1 null subjects than GSTM1 functional subjects. The apparent drug clearance was 13-fold lower in GSTM1 null subjects than GSTM1 functional subjects (p < 0.001). By metabolomics analysis, we identified that the study drug was metabolized by cysteinylglycine conjugation in GSTM functional subjects but those not in GSTM1 null subjects. The incidence rate and the severity of ADRs were higher in the GSTM1 null subjects than the GSTM1 functional subjects. Through the integrated omics analysis, we could understand the mechanism of inter-individual variability in drug exposure and in adverse response. In conclusion, integrated multi-omics analysis can be useful for elucidating the various characteristics of new drug candidates in early phase clinical trials.
The change of water level in reservoirs is an important factor causing failure of bank slopes, i.e. landslide. The water level of Three Gorges reservoir in China fluctuate between 145 m and 175 m, as a matter of flood control. During its normal operational state, the rate of water level fluctuation is supposed to range from 0.67 m/d to 3.0 m/d. Majiagou slope is located on the left bank of Zhaxi River, 2.1 km up from the outlet. Zhaxi River is a tributary of the Yangtze River within the Three Gorges area, of which the water level changes with the reservoir. At the back of Majiagou slope, a 20 m long and 3~10 cm wide fissure developed just after the reservoir water level rose from 95 m to 135 m in 2003. This big fissure was a full suggestion of potential failure of this slope. In this study, unsaturated-saturated seepage analyses were carried out to simulate the change of pore-water pressures in the bank slope subjected to the reservoir water level change. The obtained pore-water pressures were then used to evaluate the change in factor of safety (FS) with reservoir water level. It was found that the phreatic line showed a delayed response with respect to the change of the reservoir water level, because the seepage through soil layer was generally slower than water flows itself. During the rising and drawdown process, the phreatic lines take the shapes of concave and convex, respectively. And the fluctuation of reservoir water level just affected the front part of the bank slope, but had little influence on the back of the slope.
The purpose of this study was to investigate the correlation between spiritual wellbeing and hope, and perceived health status of teachers. Subjects for this study were 244 teachers sampled from middle schools in Kyungpuk. Data was collected from August 10, 1998 to August 30, 1998 using a self-reporting questionnaire managed by a trained interviewer. The measurement tool for spiritual wellbeing was a self-report questionnaire which consisted of 20 questions as 6 point Likert scale developed by Palautzian and Ellison(1982). The tool used do measure hope was developed based on a questionnaire consisting of 4 point Likert scale. Analysis of the data done by use of descriptive statistical methods, t-test, Pearson correlation. The result of this study are as follows : 1. The mean score for spiritual wellbeing was 82.32 and the range was 48-120. Among the components of spiritual wellbeing, the mean score for religious wellbeing was 39.23 and for existential wellbeing, 43.09. 2. The mean score for hope in the teacher group was 84.43, and in the school health teacher group, 88. 33, and this was statistically significant. 3. The response rate on good health for the perceived health status questions in the teacher group, 48.2%, and in the school health teacher group, 42.4%. 4. In testing the hypothesis concerning the relationship between spiritual wellbeing and hope, there was a strong positive correlation in both groups. In a comparison of coefficients of religious, existential wellbeing and hope, there was more stronger correlation in existential wellbeing than that in the other two. 5. In testing the hypothesis concerning the relationship between spiritual wellbeing and perceived health status, there was a weak positive correlation in both groups. 6. The mean score for spiritual wellbeing in the school health teacher group was higher than that in the teacher group and the difference was statistically significant. From the above results it can be conclude that : 1. There was strong positive correlation between spiritual wellbeing and hope. 2. There was correlation between spiritual wellbeing and perceived health status. 3. There was difference for spiritual wellbeing between the school health teacher group and the teacher group, and this was statistically significant.
Weights can be made and imposed in both sample design stage and analysis stage in a sample survey. While in design stage weights are related with sample data acquisition quantities such as sample selection probability and response rate, in analysis stage weights are connected with external quantities, for instance population quantities and some auxiliary information. The final weight is the product of all weights in both stage. In the present paper, we focus on the weight in analysis stage and investigate the effect of such weights imposed on the weighted mean when estimating the population mean. We consider a finite population with a pair of fixed survey value and weight in each unit, and suppose equal selection probability designs. Under the condition we derive the formulas of the bias as well as mean square error of the weighted mean and show that the weighted mean is biased and the direction and amount of the bias can be explained by the correlation between survey variate and weight: if the correlation coefficient is positive, then the weighted mein over-estimates the population mean, on the other hand, if negative, then under-estimates. Also the magnitude of bias is getting larger when the correlation coefficient is getting greater. In addition to theoretical derivation about the weighted mean, we conduct a simulation study to show quantities of the bias and mean square errors numerically. In the simulation, nine weights having correlation coefficient with survey variate from -0.2 to 0.6 are generated and four sample sizes from 100 to 400 are considered and then biases and mean square errors are calculated in each case. As a result, in the case or 400 sample size and 0.55 correlation coefficient, the amount or squared bias of the weighted mean occupies up to 82% among mean square error, which says the weighted mean might be biased very seriously in some cases.
Kim, Dong-Bae;Cho, Hak-Lae;Choi, Jae-Sung;Choi, Sun-Hee
Korean Journal of Social Welfare
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v.35
/
pp.31-50
/
1998
The purpose of this study to provide implications for improvement of Korean voluntary sector, by analyzing of program managers' subjective evaluation of voluntary program management and of their view of the needs for outside supports. For this, researchers selected 600 agencies, which are found to have a staff in charge of voluntary programs, and sent a questionnaire by mail. Those agencies are consisted of the following three. areas: social services, civil movement, public sector. The response rate was 65%, and researchers analyzed 382 respondents out of 391, besides those who did not complete the form in full. One of the results was that program managers' subjective evaluation score of overall voluntary program management was 51 points in the perfect score of 100 points. The voluntary program management was consisted of the following six areas: recruiting, job placement, public relations, education(training), program development, and. information system Specifically, program development and information system appeared to be worse than the other areas, and this fact was true in all three types of agencies of social services, civil movements, and public sector. Moreover, program managers in public sector showed that outside supports for voluntary programs (or activities) was more desperately required. Based on the results, researchers concluded that, toward the improvement of voluntary programs, professionalization as well as legal supporting system, networking, and national supporting institution were required.
The Journal of Korean Institute of Communications and Information Sciences
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v.35
no.3B
/
pp.380-389
/
2010
Since the internet is intend to be the best effort service, the system that stream a large amount of high quality medias need a techniques to overcome the network status for implementation. In this paper, we design and implement a method that estimate quickly whether network permits the needed bandwidth of media and a method that control QoS through that. Presented system uses Relative One-Way Delay(ROWD) trend in the case of the former, and leverages temporal encoding among Scalable Video Coding(SVC) that is apt to apply real time comparatively in the case of the latter. The streaming server classifies the medias by real time to several rates and begins transmission from top-level and is reported ROWD trend periodically from the client. In case of the server reported only 'Increase Trend', the sever decides that the current media exceeds the available bandwidth and downgrades the next media level. The system uses probe packet of difference quantity of the target level and the present level for upgrading the media level. In case of the server reported only 'No Increase Trend' by the ROWD trend response of the probe packet from client, the media level is upgraded. The experiment result in a fiber to the home(FTTH) environment shows progress that proposed system adapts faster in change of available bandwidth and shows that quality of service also improves.
Journal of the Korean Society for Aeronautical & Space Sciences
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v.33
no.9
/
pp.73-80
/
2005
This paper addresses a newly proposed start-up method of the HAUSAT-2 momentum wheel. The HAUSAT-2 is a 25kg class nanosatellite which is stabilized to earth pointing by 3-axis active control method. A momentum wheel performs two functions. It provides a pitch-axis momentum bias while measuring satellite pitch and roll attitude. Pitch control is accomplished in the conventional way by driving a momentum wheel in response to pitch attitude errors. Precession control and nutation damping are provided by driving the pitch axis magnetic torquer. A momentum wheel is nominally spinning at a particular rate and changes speed. This simulation study investigates the feasibility and performance of a proposed strategy for starting-up the wheel. A proposed strategy to start-up the wheel shows that a pitch momentum wheel can be successfully started-up to its nominal speed from rest and be stabilized to nadir pointing.
It was introduced a seismic mini-array that could monitor microseismicity efficiently and analyzed seismic data obtained from the mini-array that was operated from December 19, 2012 to January 9, 2013. The mini-array consisted of a six channel data logger, a central 3 components seismometer, and a tripartite array of vertical sensors centered around the 3 components seismometer as an equilateral triangle with about 100 m aperture. All seismometers that had the same instrument response were connected a 6 channel data logger, which was set to record seismograms at a sampling rate of 200 sps. During the three weeks of campaign, a total of 16 microearthquakes were detected. Using time differences of P wave arrivals from the vertical components, S-P time from 3 components seismometers, and back azimuth from the seismic array analysis, it was possible to locate the hypocenter of the microearthquake even with one seismic miniarray. The epicenters of two nearest microearthquakes were a quarry site located 1.3 km from the mini-array. The records of quarry blasting confirmed the our analysis.
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