• The Korean Journal of Physiology
• /
• 제6권2호
• /
• pp.1-8
• /
• 1972

A study was planned to see if the mammillary bodies have any influence upon orienting response Thirty-nine male rats were divided into two groups. One group of animals received electrolytic lesion of the mammillary bodies through stereotaxically implanted electrodes (mammillary body group), and the other group received the same treatment short of electrolytic lesion(operated control group). All animals were tested for orienting response 3 weeks after surgery. Orienting response was regarded as elicited when an animal in alertness ceased ongoing activity upon 1,000 Hz tone presentation and/or turned head toward the source of stimulus. Weak (momentary and inconspicuous) and strong (marked and more persistent) responses were discriminated. Occurrence and duration of orienting response were measured, and the rate of habituation was estimated in 20 trials. Shift of attention from sound to light stimulus (10 trials) as well as orienting response of thirsty animals to sound stimulus while drinking (5 trials) and while at rest (5 trials) were also tested. 1. Simple orienting respons to sound stimulus tended to occur more often and its duration tended to be shorter in the mammillary body group than in the operated control group. 2. With repetition of trials, the occurrence of orienting response in each trial decreased progressively in both groups (habituation). However, the rate of habituation was significantly less prominent in the mammillary body group than in the operated control group. 3. Under attention·shift situation, orienting response tended to occur less often and its duration tended to be shorter in the mammillary body group than in the operated control group. 4. Orienting response to sound stimulus while drinking to quench thirst tended to occur more often and its duration tended to be shorter in the mammillary body group than in the operated control group. In quiet state, however, there existed no group difference with regard to the occurrence and duration of the orienting response. Although no obvious inference can be drawn from the above results, they may suggest the mammillary bodies being involved in the orienting response as a control mechanism inhibitory to the occurrence and facilitatory to the habituation of the response.

• The Journal of Asian Finance, Economics and Business
• /
• 제9권7호
• /
• pp.27-39
• /
• 2022

The exchange rate is an important macroeconomic variable that influences internal and external balances. Nepal follows a dual exchange rate such that the Nepali rupee (NPR) is pegged with the Indian rupee (INR) but floats with the United States dollar (USD) and all other currencies. There have been very few studies on the exchange rate of Nepal, of which the majority focus on the bivariate relationship between exchange rate and another variable. However, this paper analyses the multivariate relationship between the USD-NPR exchange rate and major macroeconomic variables. Determinants of Nepal's exchange rate have been derived with multiple regression using the ordinary least square (OLS) approach. Since the explanatory variables could not significantly capture the movement of the dependent variable, a long-run relationship between Nepal and India's exchange rate has been analyzed using Engle-Granger cointegration to establish a relationship as suggested by a graphical representation. This explains that Nepal's exchange rate long run is determined by India's exchange rate than its own fundamentals. In addition, the macro-linkages of Nepal's macroeconomic variables have been analyzed using Standard Vector Autoregressive models followed by impulse response analysis which is useful for policy decisions. Some policy implications indicating the sustainability of Nepal's pegged regime have been drawn based on the empirical analysis.

• 한국안전학회지
• /
• 제13권4호
• /
• pp.59-70
• /
• 1998

In this study, response time index(RTI) of standard and quick response type sprinkler head are measured and compared through ramp and plunge test in heated wind tunnel. Also discharge rate and water distribution, actual delivered density(ADD), fire test with wood cribs are performed to compare the fire suppression capability and the operation time and temperature between standard and quick response type sprinkler head.

• 한국축산시설환경학회지
• /
• 제3권1호
• /
• pp.1-12
• /
• 1997

This study was conducted to investigate the combined effects of VFA composition of rumen fluid and heat exposure (30${\pm}$2$^{\circ}C$) on the general clinical view and insulin secretory response to glucose in sheep. The total infusion of nutrients was examined in sheep via the technique of continuous alimentation. Four adult Suffolk sheep fitted with a permanent ruminal cannula and a simple T-shaped duodenal cannula were used. A peristaltic pump was used to infuse the solutions of volatile fatty acid triglycerides (VFA-TG) consisting of 70 triacetin : 20 tripropionin : 10 tributyrin (low propionin division: LP) and 50 triacetin : 40 tripropionin : 10 tributyrin (high propionin division: HP) on the basis of energy and minerals into the rumen, and casein solution into the duodenum. The effects of heat exposure and type of the levels of VFA-TG solutions on the insulin secretory response to glucose in sheep were investigated by using hyperglycemic clamp (HGC) technique. The results obtained are summarized as follows: 1. During the heat exposure (latter half of the infusion period), respiration rate, heart rate and rectal temperature increased (P＜0.01, P＜0.01, P＜0.05), but the levels of VFA-TG solutions (LP and HP division) did not affect the general clinical view except for the heart rate. 2. In the HGC technique, glucose infusion rate (GIR) and mean plasma insulin increments (MPII) tended to be ower in the heat exposure than in the thermoneutral environment, but no significant difference was found among the treatments. GIR and MPII remained unchanged between the levels of VFA-TG solutions. 3. In the HGC technique, ratio of MPII to GIR (MPII/GIR) which represents pancreatic ${\beta}$-cell response to glucose stimulation remained unchanged among the treatments.

• 응용통계연구
• /
• 제31권5호
• /
• pp.587-597
• /
• 2018

조사목적에 부합하는 표본 자료를 얻기 위해서는 추출방법 및 조사방법 결정, 설문지 작성 등의 절차가 필요하며 중요한 결정 중 하나가 표본크기 공식의 적용이다. 표본크기 공식은 추출방법에 따른 목표오차와 총비용 등을 설정함으로써 결정되는데 본 논문에서는 단순임의추출에서 목표오차와 예상 응답률이 주어져 있을 때 과거 및 현재 시점의 모집단의 변동과 과거 자료의 추정오차 및 응답률을 사용한 표본크기 공식을 제안한다. 실제조사에서는 설계가중치 외에도 여러 가중치가 복합적으로 적용되는 추정량을 사용하고 있는데 본 논문에서는 설계가중치와 무응답 보정계수를 사용한 추정량에서의 표본크기 공식을 유도하며 이것은 시점별 조사방법이 달라질 경우 응답률에 차이가 발생하는 현상을 반영한 공식이 될 수 있다. 또한 모의 실험을 통하여 기존의 표본크기 공식과 비교함으로써 제안된 공식의 다양한 적용방안을 살펴본다.

• 대한전자공학회논문지
• /
• 제25권3호
• /
• pp.269-275
• /
• 1988

In this paper, a high efficiency motor drive system which improves the multi-step response of PM step motors by reducing the transition time of the motor drive current, is studied by designing a dual-voltage drive circuit. The designed drive circuit eventually prevents the motor from decreasing drive torque while the stepping rate is increased. The method of designing a dual-voltage drive circuit with the motor specifications is suggested in order to improve the response of step rate and drive efficiency. Also, despite improving the power efficiency on motor driving, the response characterstics suggested by the motor manufacture's specifications are satisfied without any special deficiency.

• Food Science and Biotechnology
• /
• 제14권1호
• /
• pp.28-31
• /
• 2005

To extract apple pectins, apple pomace (AP) was extruded under 14 different conditions of screw speed (250-350 rpm), feed rate of 30-40 kg/hr, and 20-30% moisture content using twin-screw extrusion. Response surface methodology (RSM), based on three variables by three-level factorial design, was employed to investigate effects of screw speed, feed rate, and moisture on dependent variables of extrudates, soluble dietary fiber (SDF), yield of anhydrogalacturonic acid ($Y_{AGA}$) representing pectin, and intrinsic viscosity ([${\eta}$]). Second order models were used to generate three-dimensional response surface for dependent variables, and their coefficients of determination ($R^2$) ranged from 0.96 to 0.99. Moisture content showed highest effect on solubilization of AP.

• 감성과학
• /
• 제7권3호
• /
• pp.27-35
• /
• 2004

본 연구는 피부전도도(skin conductance response), 말초혈관 반응(peripheral plethysmograph), 피부온도 (skin temperature)와 심박수(heart rate)와 같은 다양한 생리신호를 측정하여 운전자의 심리반응을 통하여 적정 운전상태를 분석하고자 하였다. 운전자의 심리반응을 측정 및 분석하기 위하여 하드웨어와 알고리듬을 개발하였으며, 운전상황은 자동차 시뮬레이터를 이용하여 다양한 가상 운전상황을 설정하고 생리신호를 측정하였다. 측정 결과 운전자 생리신호가 운전환경의 변화에 따른 심리적 긴장 또는 이완 수준을 잘 반영하고 있고, 감정적 변화에는 다소 둔감한 것으로 나타났다. 이를 심리적 순위척도를 이용하여 정량화하여 심리적 적정 운전범위를 제안하였다. 본 연구의 결과는 추후 운전자의 안전운전이나 건강상태를 모니터링 하기 위한 시스템 개발의 자료로 활용할 수 있을 것이다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권22호
• /
• pp.9763-9766
• /
• 2014

Background: This systemic analysis was conducted to evaluate the efficacy and safety of an ifosfamide-containing regimen in treating patients with osteosarcoma. Methods: Clinical studies evaluating the efficacy and safety of Ifosfamide-containing regimen on response and safety for patients with osteosarcoma were identified by using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: When ifosfamide-containing regimens were evaluated, 4 clinical studies which including 134 patients with osteosarcoma were considered eligible for inclusion. Systemic analysis suggested that, in all patients, pooled RR was 44.8% (60/134) in ifosfamide-containing regimens. Major adverse effects were neutropenia, leukopenia, and fatigue inIfosfamide-containing regimens; No treatment related death occurred in cantharidin combined regimens. Conclusion: This systemic analysis suggests that ifosfamide-containing regimens are associated with good response rate and acceptable toxicity in treating patients with osteosarcoma, but this result should be confirmed by randomized clinical trials.

• Radiation Oncology Journal
• /
• 제7권1호
• /
• pp.45-50
• /
• 1989

From Feb.1985 to Feb.1988,76 patients with squamous cell carcinoma of the lung treated at the Department of Therapeutic Radiology in Kyungpook National University Hospital were available for the analysis of this study. All patients received radiation of 4000cGy-6600cGy with curative aim. The overall rate of complete response was 25.0% and partial response was 452.6% The complete and partial regression of tumor was 14.3% in patients treated with dose below 5000cGy and 84.1% in the group treated with dose above 5000cGy (p<0.01). The complete response was seen only in the group of patients received radiation at least 6000cGy. The patterns of failure were as follows. The rate of initial intrathoracic recurrence was 52.6% in patients with complete response. The overall rate of failure was 68.8%. Distant metastasis was found in 47.4% of patients. Bone, contralateral lung, and brain were common metastatic sites in decreasing order All of the distant metastases and 80% of local recurrences were found within the first year after treatment.