• Tuberculosis and Respiratory Diseases
• /
• 제50권2호
• /
• pp.196-204
• /
• 2001

기관지 천식은 가역적인 기도수축과 기도과민성 및 기도 염증을 특정으로 하는 만성염증성 질환으로 이중 호산구는 기관지천식의 병태생리 기전 중에서 기관지점막 상피세포의 손상을 초래하여 궁국적으로 기도과민성을 초래하는 것으로 알려져 있다. 또한 천식환자의 혈액, 기관지 폐포세척액 및 기관지 점막내의 호산구 증가는 기관지 폐쇄정도 및 기도과민성과 연관성이 있다고 보고되고 있으며, 활성화된 호산구 수와 혈중 ECP는 유의한 상관관계를 보인다고 보고하고 있고, 기관지천식의 경과 판정에 유용한 지표로 제시되었으나, 정확한 임상적 유용성이 확립된 바는 없다. 이에 혈중 ECP 농도를 측정하여, 즉시형의 가역적인 기도확장반응과 기도과민성($PC_{20}$)과의 관계를 알아보고 말초혈액 호산구수와 비교하여 혈중 ECP의 유용성을 평가하고자 하였다. 기관지천식으로 진단되었던 환자 중 일초간 호기량의 에측치($FEV_1$ % p)가 80% 이하이었던 중등증 및 중증 천식환자 71명을 대상으로 하여, 말초혈액을 채취하여 호산구수와 총 IgE농도, ECP를 측정하였고, 기관지확장제에 대한 반응과 메타콜린 기관지 유발검사를 시행하였다. 기관지확장제에 대한 반응군과 비반응군간에 나이, 성별에 통계적 차이는 없었으며, 총 IgE, $FEV_1$/FVC(%), $FEV_1$(% to predictive value) 등에도 통계적 차이는 없었으며 호산구수도 두 군간의 유의한 차이를 보이지 않았다. 하지만 ECP농도는 통계적으로 반응군에서 유의하게 반응군에서 높았으며 $PC_{20}$은 반응군에서 의미있게 낮았다. 그리고 기관지 확장제의 반응 정도와 혈중 ECP농도 및 기도과민성과의 관계에서 혈중 ECP 농도는 순 상관관계를 보였고 기도과민성($PC_{20}$)과는 역 상관관계를 보였다. 또한 혈중 ECP농도와 기도과민성과도 통계적으로 의미 있는 상관관계를 보였다. 이상의 결과로 혈중 ECP농도는 중등증 및 중증 기관지천식환자에서 급성 기도수축 정도와 기도과민성을 잘 반영하며, 천식의 치료와 임상경과 및 예후에 의미있는 지표로 이용될 수 있을 것으로 생각되며, 기관지 확장제의 반응성은 기관지의 염증과 연관될 것으로 생각된다. 또한 추후로 환자의 임상상과 천식의 정도 및 약물치료에 따른 ECP의 변화에 대한 연구가 필요할 것으로 생각된다.

• 한국펄프종이공학회:학술대회논문집
• /
• 한국펄프종이공학회 2004년도 춘계학술발표논문집
• /
• pp.107-114
• /
• 2004

In this work the Model algorithmic control method is applied to control the grade change operations in paper mills. The neural network model for the grade change operations is identified first model is then extracted from the neural model. Results of simulations for MAC control of grade change operations are compared with plant operation data response. From the comparison, we can see that the proposed MAC method exhibits faster response for the grade change of paper and achieves stable steady-state.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제13권3호
• /
• pp.1345-1362
• /
• 2019

Most active queue management algorithms manage network congestion based on the size of the queue but ignore the network environment which makes queue size change. It seriously affects the response speed of the algorithm. In this paper, a new AQM algorithm named CT-AQM (Change Trend-Adaptive Queue Management) is proposed. CT-AQM predicts the change trend of queue size in the soon future based on the change rate of queue size and the network environment, and optimizes its dropping function. Simulation results indicate that CT-AQM scheme has a significant improvement in loss-rate and throughput.

• 한국지반공학회:학술대회논문집
• /
• 한국지반공학회 2009년도 춘계 학술발표회
• /
• pp.620-625
• /
• 2009

The seismic slope stability is most often evaluated by the pseudo-static limit analysis, in which the earthquake loading is simplified as static inertial loads acting in horizontal and/or vertical directions. The transient loading is represented by constant acceleration via the pseudostatic coefficients. The result of a pseudostatic analysis is governed by the selection of the value of the pseudostatic coefficient. However, selection of the value is very difficult and often done in an ad hoc manner without a sound physical reasoning. In addition, the maximum acceleration is commonly estimated from the design guideline, which cannot accurately estimate the dynamic response of a slope. There is a need to perform a 2D dynamic analysis to properly define the dynamic response characteristics. This paper develops the modified one-dimensional seismic site response analysis. The modified site response analysis adjusts the density of the layers to simulate the change in mass and weight of the layers of the slope with depth. Multiple analyses are performed at various locations within the slope to estimate the change in seismic response of the slope. The calculated peak acceleration profiles with depth from the developed procedure are compared to those by the two-dimensional analyses. Comparisons show that the two methods result in remarkable match.

• 한국시뮬레이션학회논문지
• /
• 제24권3호
• /
• pp.45-54
• /
• 2015

본 논문에서는 기어감속 서보시스템의 모터입력전압 크기를 적절히 감소시키면 모터입력전압에 대한 모터각속도에서 나타나는 주파수응답특성에 미치는 백래시 영향이 매우 커지게 됨을 보여 주였다. 또한 주파수응답선도에서 나타나는 반공진 및 공진주파수 변화량을 관찰하여 기어감속 서보시스템 내 기어 백래시 변화를 감지할 수 있는 방법의 유용성을 이론적, 시뮬레이션 및 실험적으로 검증하였다. 반공진주파수 변화가 공진주파수 변화 보다 안정적으로 계측될 수 있으므로 백래시 크기 변화감지 시 반공진주파수 변화량 관찰이 좀 더 유용하며, 공진주파수는 모터입력전압을 충분히 감속시켜야 급격한 변화를 관찰할 수 있음을 보여주었다. 본 연구는 기어감속 서보시스템 내 백래시 크기 변화 감지에 대한 향후 연구에 있어서 유용하게 사용될 수 있을 것이라고 생각한다.

• 한국양식학회지
• /
• 제12권3호
• /
• pp.221-228
• /
• 1999

The effects of sparp changes of water temperature (WT) on the stree response and physiological change of the cultured olive flounder (Paralichthys olivaceus) were examined by manipulating WT (3 patterns) in a running seawater culture system. In the first group (Exp. I), the WT was decreased from 18$^{\circ}C$ to 11$^{\circ}C$ within 6 hours and increased back to the original WT quickly. WT was decreased from 2$0^{\circ}C$ to 11$^{\circ}C$ within 5 hours and main-tained at 11$^{\circ}C$ for 10 hours. and then increased to 2$0^{\circ}C$ in the second group (Exp. II). In the third group(Exp. III) WT was decreased to 11$^{\circ}C$ within 5 hours (type A) or 10 hrs. (type B). In Exp. I and III, the level of serum cortisol was increased from 2.5$\pm$0.3 ng/ml and 2.6$\pm$0.9 ng/ml to 13.6$\pm$3.0 ng/ml and 12.4$\pm$3.2ng/ml, respectively, with WT decrease. However, no consistent tendency in the change of serum glucose level was shown according to WT decrease. In Exp. III, the glucose level of fish in type A was decreased until 5 hours and increased at 7 hours, then decreased until 12 hours where as the glucose level in type B was decreased until 5 hours and stayed at the level of 15.7 mg/dl. The serum osmolality was reduced with WT decrease and the response of serum electrolytes in this experiment conflicted, and a tendency in total protein, AST and ALT was not found following WT decrease. In conclusion, olive flounder responded to the stress caused by WT decrease and acclimated to this condition when the lower temperature was maintained. But there was no stress response in the blood of olive flounder when WT was increased. On the other hand, the degree of stress response in olive flounder was various according to the range and gradient of WT change.

• 한국보육지원학회지
• /
• 제5권1호
• /
• pp.59-79
• /
• 2009

본 연구는 구성주의 교수방법이 유아의 과학적 개념변화에 있어서 나타나는 연령에 따른 개념변화의 정도를 유아의 반응에 따라 분석함으로써 그 효과를 알아보는 데 목적이 있다. 연구를 위해 어린이집에 재원중인 3, 4, 5세 유아 34명을 연구대상으로 하였으며, 6개의 과학개념에 대해 구성주의 교수방법을 적용하여 개념변화 수업을 실시하였다. 구성주의 교수방법의 연령별 효과를 알아보기 위해 각 집단에 대한 사전-사후검사를 실시하여 유아의 정, 오반응의 비율을 비교하고, 반응내용을 범주화하여 반응유형을 분석하였다. 연구의 결과 구성주의 교수방법이 유아의 과학적 개념변화에 효과적인 것으로 나타났으며, 또한 구성주의 교수방법은 유아의 연령이 높을수록 그 효과가 더 큰 것으로 나타났다.

• Smart Structures and Systems
• /
• 제18권2호
• /
• pp.217-231
• /
• 2016

The present work aims to develop piezoresistive sensors of excellent piezoresistive response attributable to change in nanoscale structures of multi-wall carbon nanotube (MWNT) embedded in cement. MWNT was distributed in a cement matrix by means of polymer wrapping method in tandem with the ultrasonication process. DC conductivity of the prepared samples exhibited the electrical percolation behavior and therefore the dispersion method adopted in this study was deemed effective. The integrity of piezoresistive response of the sensors was assessed in terms of stability, the maximum electrical resistance change rate, and sensitivity. A composite sensor with MWNT 0.2 wt.% showed the lowest stability and sensitivity, while the maximum electrical resistance change rate exhibited by this sample was the highest (96 %) among others and even higher than those found in the literature. This observation was presumably attributed by the percolation threshold and the tunneling effect. As a result of the MWNT content (0.2 wt.%) of the sensor being near the percolation threshold (0.25 wt.%), MWNTs were close to each other to trigger tunneling in response of external loading. The sensor with MWNT 0.2 wt.% was able to maintain the repeatable sensing capability while sustaining a vehicular loading on road, demonstrating the feasibility in traffic flow sensing application.

• The Journal of Korean Physical Therapy
• /
• 제34권2호
• /
• pp.51-56
• /
• 2022

Purpose: This study examined the effects of gym ball stabilization exercises on the physical functions of elementary school baseball players. Methods: The elementary school baseball players were assigned to an experimental group (n=21). The group performed gym ball stabilization exercises and the changes in the physical functions were measured using the visual response speed test, functional movements, physical balance ability, and pulmonary function. Results: The results of the visual response speed test showed changes in the time response speed. There was a significant change in the number of touches in 15 seconds in the upper arms and left and right legs (p<0.05) after 10 weeks. Also, there was a significant change in the reaction times of the left and right legs after 10 weeks (p<0.05). Further, there were significant differences in functional movements involving rotational stability and the total functional scores after 10 weeks (p<0.05). The player's body balance ability showed a significant difference after 10 weeks in the posterior-lateral and posterior-medial composite scores of the left and right legs (p<0.05). There was a significant change in the forced lung capacity and forced expiratory volume in 1 second after 10 weeks (p<0.05). Conclusion: These results show that the gym ball stabilization exercises effectively improved the visual response speed and functional movements, balance, and vital capacity of elementary school baseball players.

• Journal of Acupuncture Research
• /
• 제19권2호
• /
• pp.39-50
• /
• 2002

Objective : The aim of this study was to investigate the effect of CMM oral administration and herbal acupuncture at BL13 LU4 on Asthma induced by ovalbumin in rats Methods : Several experimental items were measured and compared each other ; that is body weight change, oxygen consumption rate, Albumin change, white blood corpuscle change, Erythrocyte change, IgE change. Results : 1. Body weight was significantly increased in herbal acupuncture group after its administration while there was no such a response in oral administration group. 2. Oxygen Consumption rate was significantly increased in oral administration group and herbal acupuncture group. 3. Albumin in serum was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 4. White blood corpuscle in blood was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 5. Erythrocyte in blood was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 6. IgE in blood was decreased in oral administration group and herbal acupuncture group but there was no significance in oral administration group and herbal acupuncture group. Conclusion : Based on the above results it is assumed that CMM oral administration and CMM herbal acupuncture can help the treatment of Asthma induced by ovalbumin in rats.