• Title/Summary/Keyword: Response Change

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The Relation Between Bronchodilator Response, Airway Hyperresponsiveness and Serum Eosinophil Cationic Protein (ECP) Level in Moderate to Severe Asthmatics (중증 및 중등증 기관지천식 환자에서 기도과민성과 기관지확장제 반응성 및 혈청 Eosinophil Cationic Protein(ECP)와의 관계)

  • Park, Sung-Jin;Kang, Soon-Bock;Kwon, Jung-Hye;Lee, Sang-Hoon;Jung, Do-Youg;Yoo, Ji-Hoon;Kim, Sang-Hoon;Kim, Jae-Yeol;Park, In-Won;Choi, Byoung-Whui
    • Tuberculosis and Respiratory Diseases
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    • v.50 no.2
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    • pp.196-204
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    • 2001
  • Background : Bronchial asthma is characterized by a reversible airway obstruction, airway hyperresponsiveness, and eosinophilic airway inflammation. The bronchodilator response(BDR) after short acting beta agonist inhalation and PC20 with methacholine inhalation are frequently used for diagnosing bronchial asthma. However, the relationship between the presence of a bronchodilator response and the degree of airway hyperresponsiveness is uncertain. Therefore, the availability of a eosinophil cationic protein (ECP) and a correlation ECP with a bronchodilator response and airway hyperresponsiveness was investigated. Method : A total 71 patients with a moderate to severe degree of bronchial asthma were enrolled and divided into two groups. 31 patients with a positive bronchodilator response and 38 patients with a negative bronchodilator response were evaluated. In both groups, the serum ECP, peripheral blood eosinophil counts, and total IgE level were measured and the methacholine bronchial provocation test was examined. Results : There were no differences observed in age, sex, atopy, and baseline spirometry in both groups. The peripheral eosinophil counts showed no difference in both groups, but the ECP level in group 1 (bronchodilator responder group) was higher than in group 2(non-bronchodilator responder group) ($22.4{\pm}20.7$ vs $14.2{\pm}10.4$, mean$\pm$SD). The PC20 in group 1 was significantly lower than in group 2 ($1.14{\pm}1.68$ vs $66{\pm}2.98$). There was a significant positive correlation between the BDR and ECP, and a negative correlation between the bronchial hyperresponsiveness and ECP. Conclusion : The bronchodilator response significantly correlated with the bronchial hyperresponsiveness and serum ECP in the moderate to severe asthma patients. Hence, the positive bronchodilator response is probably related with active bronchial inflammation and may be used as a valuable index in treatment, course and prognosis of bronchial asthma.

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Model Algorithmic Control of Grade Change Operations in Paper Mills (지종교체 공정의 예측제어)

  • Park, Jong-Ho;Yeo, Yeong-Gu;Kim, Yeong-Gon;Gang, Hong
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2004.04a
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    • pp.107-114
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    • 2004
  • In this work the Model algorithmic control method is applied to control the grade change operations in paper mills. The neural network model for the grade change operations is identified first model is then extracted from the neural model. Results of simulations for MAC control of grade change operations are compared with plant operation data response. From the comparison, we can see that the proposed MAC method exhibits faster response for the grade change of paper and achieves stable steady-state.

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Adaptive Queue Management Based On the Change Trend of Queue Size

  • Tang, Liangrui;Tan, Yaomu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.3
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    • pp.1345-1362
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    • 2019
  • Most active queue management algorithms manage network congestion based on the size of the queue but ignore the network environment which makes queue size change. It seriously affects the response speed of the algorithm. In this paper, a new AQM algorithm named CT-AQM (Change Trend-Adaptive Queue Management) is proposed. CT-AQM predicts the change trend of queue size in the soon future based on the change rate of queue size and the network environment, and optimizes its dropping function. Simulation results indicate that CT-AQM scheme has a significant improvement in loss-rate and throughput.

Estimation of amplification of slope via 1-D site response analysis (1차원 지반응답해석을 통한 사면의 증폭특성 규명)

  • Yun, Se-Ung;Park, Du-Hee
    • Proceedings of the Korean Geotechical Society Conference
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    • 2009.03a
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    • pp.620-625
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    • 2009
  • The seismic slope stability is most often evaluated by the pseudo-static limit analysis, in which the earthquake loading is simplified as static inertial loads acting in horizontal and/or vertical directions. The transient loading is represented by constant acceleration via the pseudostatic coefficients. The result of a pseudostatic analysis is governed by the selection of the value of the pseudostatic coefficient. However, selection of the value is very difficult and often done in an ad hoc manner without a sound physical reasoning. In addition, the maximum acceleration is commonly estimated from the design guideline, which cannot accurately estimate the dynamic response of a slope. There is a need to perform a 2D dynamic analysis to properly define the dynamic response characteristics. This paper develops the modified one-dimensional seismic site response analysis. The modified site response analysis adjusts the density of the layers to simulate the change in mass and weight of the layers of the slope with depth. Multiple analyses are performed at various locations within the slope to estimate the change in seismic response of the slope. The calculated peak acceleration profiles with depth from the developed procedure are compared to those by the two-dimensional analyses. Comparisons show that the two methods result in remarkable match.

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The Utilization of Frequency Response Characteristic for the Detection of Change of Backlash Magnitude (백래시 크기 변화 감지를 위한 주파수응답특성의 활용)

  • Baek, Joo-Hyun
    • Journal of the Korea Society for Simulation
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    • v.24 no.3
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    • pp.45-54
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    • 2015
  • This paper presents the influence of backlash can be greatly increased on the frequency response characteristic which is presented as the angular velocity of a motor to the motor input voltage, if the motor input voltage is adequately reduced. And, this paper verifies theoretically, analytically and experimentally the availability on the method of detecting the change of backlash magnitude by investigating on the change of the anti-resonance and resonance frequencies in the frequency response characteristic due to the change of backlash magnitude. The amount of change of anti-resonance frequency is more useful that of resonance frequency when detecting the change of backlash magnitude, because the change of anti-resonance frequency can be measured more stable. This paper also shows the sharp change of resonance frequency can be investigated when the motor input voltage is enough reduced. The work will be useful for the further research on the backlash estimation method of a servo system with a gear reducer.

Physiological Response of the Cultured Olive Flounder (Paralichthys olivaceus) to the Sharp changes of Water Temperature (급격한 수온변화에 따른 양식 넙치(Paralichthys olivaceus)의 생리적 반응)

  • 박명룡;장영진;강덕영
    • Journal of Aquaculture
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    • v.12 no.3
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    • pp.221-228
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    • 1999
  • The effects of sparp changes of water temperature (WT) on the stree response and physiological change of the cultured olive flounder (Paralichthys olivaceus) were examined by manipulating WT (3 patterns) in a running seawater culture system. In the first group (Exp. I), the WT was decreased from 18$^{\circ}C$ to 11$^{\circ}C$ within 6 hours and increased back to the original WT quickly. WT was decreased from 2$0^{\circ}C$ to 11$^{\circ}C$ within 5 hours and main-tained at 11$^{\circ}C$ for 10 hours. and then increased to 2$0^{\circ}C$ in the second group (Exp. II). In the third group(Exp. III) WT was decreased to 11$^{\circ}C$ within 5 hours (type A) or 10 hrs. (type B). In Exp. I and III, the level of serum cortisol was increased from 2.5$\pm$0.3 ng/ml and 2.6$\pm$0.9 ng/ml to 13.6$\pm$3.0 ng/ml and 12.4$\pm$3.2ng/ml, respectively, with WT decrease. However, no consistent tendency in the change of serum glucose level was shown according to WT decrease. In Exp. III, the glucose level of fish in type A was decreased until 5 hours and increased at 7 hours, then decreased until 12 hours where as the glucose level in type B was decreased until 5 hours and stayed at the level of 15.7 mg/dl. The serum osmolality was reduced with WT decrease and the response of serum electrolytes in this experiment conflicted, and a tendency in total protein, AST and ALT was not found following WT decrease. In conclusion, olive flounder responded to the stress caused by WT decrease and acclimated to this condition when the lower temperature was maintained. But there was no stress response in the blood of olive flounder when WT was increased. On the other hand, the degree of stress response in olive flounder was various according to the range and gradient of WT change.

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A study on the effect of constructive instruction and analysis of response pattern of on scientific concepts among 3, 4, 5 years old (구성주의 교수방법에 의한 유아의 연령별 과학 개념변화 및 반응유형 분석)

  • Park, Choong ll;Kim, Sin Gon
    • Korean Journal of Childcare and Education
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    • v.5 no.1
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    • pp.59-79
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    • 2009
  • The purpose of this study to analysis the response pattern of the constructive instruction model that reflect constructivism learning theory for change on 6 science concepts. Specially, this study analyzes the constructive instruction model's effect among 3, 4, 5 years old and explain to the 6 scientific concepts that change from false response to correct response. The subjects are 34 public institution children who located in the Jinju city and was need to explain the scientific concepts. For the response pattern analysis of the this study is using scientific conceptual task on the function of ear and blood, the reason of thunder, typhoon, evaporation and ship's flotage. Conclusions that appear through result of constructivism activities effect on change of six scientific concepts and the constructive instruction's effect is more 5 year old than 3, 4 years old age.

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Percolation threshold and piezoresistive response of multi-wall carbon nanotube/cement composites

  • Nam, I.W.;Souri, H.;Lee, H.K.
    • Smart Structures and Systems
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    • v.18 no.2
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    • pp.217-231
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    • 2016
  • The present work aims to develop piezoresistive sensors of excellent piezoresistive response attributable to change in nanoscale structures of multi-wall carbon nanotube (MWNT) embedded in cement. MWNT was distributed in a cement matrix by means of polymer wrapping method in tandem with the ultrasonication process. DC conductivity of the prepared samples exhibited the electrical percolation behavior and therefore the dispersion method adopted in this study was deemed effective. The integrity of piezoresistive response of the sensors was assessed in terms of stability, the maximum electrical resistance change rate, and sensitivity. A composite sensor with MWNT 0.2 wt.% showed the lowest stability and sensitivity, while the maximum electrical resistance change rate exhibited by this sample was the highest (96 %) among others and even higher than those found in the literature. This observation was presumably attributed by the percolation threshold and the tunneling effect. As a result of the MWNT content (0.2 wt.%) of the sensor being near the percolation threshold (0.25 wt.%), MWNTs were close to each other to trigger tunneling in response of external loading. The sensor with MWNT 0.2 wt.% was able to maintain the repeatable sensing capability while sustaining a vehicular loading on road, demonstrating the feasibility in traffic flow sensing application.

Effects of Gym Ball Stabilization Exercises on the Physical Functions of Elementary School Baseball Players

  • Kim, Se-Hun;Park, Jea-Cheol
    • The Journal of Korean Physical Therapy
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    • v.34 no.2
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    • pp.51-56
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    • 2022
  • Purpose: This study examined the effects of gym ball stabilization exercises on the physical functions of elementary school baseball players. Methods: The elementary school baseball players were assigned to an experimental group (n=21). The group performed gym ball stabilization exercises and the changes in the physical functions were measured using the visual response speed test, functional movements, physical balance ability, and pulmonary function. Results: The results of the visual response speed test showed changes in the time response speed. There was a significant change in the number of touches in 15 seconds in the upper arms and left and right legs (p<0.05) after 10 weeks. Also, there was a significant change in the reaction times of the left and right legs after 10 weeks (p<0.05). Further, there were significant differences in functional movements involving rotational stability and the total functional scores after 10 weeks (p<0.05). The player's body balance ability showed a significant difference after 10 weeks in the posterior-lateral and posterior-medial composite scores of the left and right legs (p<0.05). There was a significant change in the forced lung capacity and forced expiratory volume in 1 second after 10 weeks (p<0.05). Conclusion: These results show that the gym ball stabilization exercises effectively improved the visual response speed and functional movements, balance, and vital capacity of elementary school baseball players.

Effects of Cordyceps militaris Mycelia(CMM) oral administration and herbal acupuncture at BL13, LU4 on asthma induced by ovalbumin in rats (동충하초(冬蟲夏草) 약침(藥鍼)과 구강투여(口腔投與)가 Ovalbumin으로 유발된 Asthma에 미치는 영향)

  • Kim, Jae-Hong;Cho, Myung-Rae;Ryu, Choong-Ryul;Chae, Woo-Suk
    • Journal of Acupuncture Research
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    • v.19 no.2
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    • pp.39-50
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    • 2002
  • Objective : The aim of this study was to investigate the effect of CMM oral administration and herbal acupuncture at BL13 LU4 on Asthma induced by ovalbumin in rats Methods : Several experimental items were measured and compared each other ; that is body weight change, oxygen consumption rate, Albumin change, white blood corpuscle change, Erythrocyte change, IgE change. Results : 1. Body weight was significantly increased in herbal acupuncture group after its administration while there was no such a response in oral administration group. 2. Oxygen Consumption rate was significantly increased in oral administration group and herbal acupuncture group. 3. Albumin in serum was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 4. White blood corpuscle in blood was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 5. Erythrocyte in blood was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 6. IgE in blood was decreased in oral administration group and herbal acupuncture group but there was no significance in oral administration group and herbal acupuncture group. Conclusion : Based on the above results it is assumed that CMM oral administration and CMM herbal acupuncture can help the treatment of Asthma induced by ovalbumin in rats.

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