• 한국산업보건학회지
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• 제22권4호
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• pp.309-315
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• 2012

Objectives: Animal husbandry workers could be exposed to various work hazards including toxic gases, chemicals such as pesticides or organic dust. Immunological evaluation focusing on respiratory allergic hypersensitivity occurrence was under-taken for swine farm workers as a part of the study on immunologic status of dairy barn, swine confinement, and poultry farm workers. Materials and Methods: Peripheral bloods were collected from 25 workers at the year of 2001 and 12 workers at the year of 2012 from swine farms located at Gyeonggi province, Korea. Seven adults not involved with animal husbandry were recruited at the year of 2001 from the same residential area as the swine farm workers'. Level of plasma IgE and 20 respiratory allergen-specific IgE were evaluated using commercially available ELISA kit. Results: Plasma IgE level was approximately five-fold higher in the swine farm workers regardless of the sampling year than the control subjects. Plant allergens from outdoor environments such as golden rod, pigweed, Russian thistle, or ragweed were the major allergens with positive reaction(allergen specific IgE${\geq}$0.7 IU/mL) for the swine farm workers at 2001 year. Meanwhile, house dust mite(Dermatophagoides farinae, D. pteronyssinus) and cockroach, typical indoor allergens in Korea, were the major respiratory allergens for the swine farm workers at 2012 year. Conclusions: Overall, even though our results are primitive, the results suggest that immunological function of swine farm workers could be modulated toward type-2 reactivity.

• 대한한의학회지
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• 제40권3호
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• pp.87-98
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• 2019

Objectives: Patients with respiratory diseases are increasing as air pollution due to fine dust gets worse. Diseases that occupy a large proportion of respiratory diseases in medical institutions are acute bronchitis, chronic bronchitis and Allergic rhinitis. The number of patients with all three diseases is gradually increasing. This study was to suggest assignment of medicine policy for improving accessibility to Korean medical treatment of respiratory diseases analyzing the current treatment status of acute bronchitis, Chronic bronchitis and Allergic rhinitis patients in Western medical and Korean medical institutes in this situation. Methods: This study used 2017 National patient sample data from the Korean Health Insurance Review and Assessment Service for research. Acute bronchitis, Chronic bronchitis, Allergic rhinitis was according to KCD code. This research contains Socio-demographic analysis classified by sex and age, the number of three disease's patients. Also the number of medical treatment, the expense of recuperation cost, medical practices were analyzed compare with Western and Korean medicine. Results: The incidence of three diseases is higher among female than male. There are many patients under the age of 10 in the case of acute bronchitis and allergic rhinitis, while there are many patients over 50 years of age in chronic bronchitis. Western medical treatment take up a larger proportion than Korean medical treatment in part of the number of three disease's patients, the number of medical treatment, the expense of recuperation cost. Conclusions: Much more patients of these diseases visit in Western medical clinic and hospital than Korean medical clinic and hospital for treatment. There are many parts of Korean medical treatment that are not covered by Health insurance benefits like herbal decoction, pharmacopuncture, etc. Korean medicine need to do the efforts for expanding medical field in variety. Also it is demanded for institutional support for reduction of the cost burden and improving on accessibility of Korean medical treatment in order to treat with the increase in respiratory diseases due to fine dust.

• Tuberculosis and Respiratory Diseases
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• 제83권2호
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• pp.116-121
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• 2020

Particulate matter (PM) is suspended dust that has a diameter of <10 ㎛ and can be inhaled by humans and deposited in the lungs, particularly the alveoli. Recent studies have shown that PM has an adverse effect on respiratory diseases. The aim of this article is to review respiratory diseases associated with PM. According to existing studies, PM is associated with chronic obstructive pulmonary disease, bronchial asthma, and several other respiratory diseases and increases the mortality rates of these diseases. Moreover, increased exposure in the high concentration of atmospheric PM is associated with the development of lung cancer. The most simple and common way to protect an individual from airborne PM is to wear a face mask that filters out PM. In areas of high concentration PM, it is recommended to wear a face mask to minimize the exposure to PM. However, the use of N95 or KF94 masks can interfere with respiration in patients with chronic respiratory diseases who exhibit low pulmonary function, leading to an increased risk of respiratory failure. Conclusionally, reduction of the total amount of PM is considered to be important factor and strengthening the national warning notification system to vulnerable patients and proper early management of exacerbated patients will be needed in the future.

• 한국농공학회논문집
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• 제57권6호
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• pp.35-46
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• 2015

Improvement in domestic poultry production has a positive effect on the export competitiveness of the poultry industry. However, overproduction and enlargement of facilities to assure a supply increase a stocking density which make a poor environment in the broiler house. In particular, an intensive rearing environment is vulnerable to dust control that causes respiratory diseases, such as asthma, bronchitis, etc., to farmers and broilers. However, monitoring data and research for environment control are not adequate, and there are no air quality regulations in broiler houses in Korea. In this study, TSP, PM10, inhalable dust and respirable dust concentration were monitored according to season, age of broiler and broiler's activities. Air quality assessment was also performed in accordance with the threshold limit value by Donham et al. (2000). The TSP concentrations were 77.5 %, 219.7 % higher and PM10 concentrations were 121.2 %, 303.8 % higher when change of season and winter respectively than summer. There were significantly different concentrations according to season and age of broiler. Inhalable and respirable dust concentration were also clearly different according to the season and age of broiler. A high dust concentration was observed, specifically exceeding the threshold limit by 119 % in the winter. In the case of the broiler's motion was activity according to worker's access into the broiler house, concentration level was 769.6 % higher than broiler's motion was stable and exceeded the threshold limit. These results suggest that the worker should put on protective equipment to protect there's respiratory health in the broiler house.

• 한국농공학회논문집
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• 제50권4호
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• pp.39-50
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• 2008

A study on fugitive dust dispersion was conducted at Saemanguem reclaimed area located at the west coastal area of Jeon-buk Province Total reclaimed area is 40,100ha developed by building a 33km long sea dike through Gunsan, Gimje, and Buan. (Land: 28,300ha, Fresh Water Lake: 11,800ha) After this area was completely reclaimed in 2006, there has been high possibility of dust generation and dispersion to the neighboring area. The dust generated at the reclaimed land was composed mainly of minerals with high salinity, and it could make harmful effect on crop production as well on to human's health such as eye irritation and respiratory disease. Especially, when those aerosol particles are reached on the leaves of farm crops, the photosynthesis and respiration of the plants can be under restraint resulting in the decrease of agricultural productivity of the nearby farm areas. Furthermore, highly concentrated salty particles can directly damage the leaf cells. In this study, field experiment has been conducted to regularly measure the locally suspended dust particles and analyze how they were dispersed to the neighboring areas. The collected dust particles were analyzed to examine theirs sizes, concentrations, and components. The SPSS statistical program was also used to separate the dust concentration generated by the reclaimed land from the total dust concentration measured at the measuring locations.

• 스마트미디어저널
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• 제7권3호
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• pp.22-28
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• 2018

미세먼지 등 다양한 원인으로 한국의 대기 오염 문제가 점점 심해지고 있다. 대기 오염 문제가 심해짐에 따라 많은 사람들이 미세먼지에 대한 관심과 건강에 대한 불안이 높아지고 있다. 따라서 미세먼지가 미치는 영향과 어떤 질환과의 상관관계가 있는 지에 대한 다양한 연구가 진행되고 있다. 하지만 단순히 미세먼지가 호흡기 및 심혈관 질환, 고혈압 그리고 당뇨병과 같은 특정 질환과의 관계가 있다고 분석하고 있다. 이에 본 논문에서는 진료내역정보 공공데이터를 활용하여 2016년도 월별 진료횟수가 가장 높은 진료과목 10개를 추출하고 피어슨 상관계수를 사용하여 미세먼지가 어떤 진료과목과 관계가 있는지 분석한다. 그리고 더 세분화하여 미세먼지와 성별과 연령대에 따른 진료과목과의 상관관계를 분석한다. 미세먼지와 진료과목이 가장 강한 양의 상관관계인 여성-중년군은 2011년부터 2015년까지의 상관관계를 분석하고 회귀 분석을 통해 연관성 계수를 추출하여 미세 먼지 농도에 따른 진료과목과의 연관성 예측 방법을 제안한다.

• 한국콘텐츠학회논문지
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• 제18권12호
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• pp.281-290
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• 2018

최근 미세먼지에 대한 관심이 높아지고 있으나, 미세먼지 인식, 지식, 태도에 대한 연구는 활발히 진행되지 않았다. 본 연구는 국내 대학생의 미세먼지 인식, 지식, 태도를 조사하고 자기효능감을 포함한 영향 요인을 알아보기 위하여 시도되었다. 본 연구는 서술적 조사연구로써 만 19세 이상 대학생 206명을 대상으로 구조화된 설문지를 이용하였다. 본 연구 결과 미세먼지 인식, 지식, 태도, 그리고 자기효능감은 유의한 양의 상관관계가 있었다. 국내 대학생은 미세먼지 인식 정도가 가장 높고, 미세먼지 지식과 태도 점수는 낮았다. 회귀분석 결과 대학생의 미세먼지 인식에 영향을 주는 요인은 학년, 호흡기질환 과거력, 자기효능감이었고 미세먼지 지식에 영향을 주는 요인은 학년과 자기효능감이었다. 따라서 대학생들의 미세먼지 지식과 태도를 높이기 위한 교육프로그램이 필요하며 이때 자기효능감을 함께 올리는 전략이 필요한 것으로 생각된다.

• 대한방사선기술학회지:방사선기술과학
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• 제45권3호
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• pp.225-232
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• 2022

Fine dust threatens human health in various forms, depending on the particle size, such as by causing respiratory, cardiovascular, and brain diseases, after entering the body via the lungs. The aim of this study was to correlate fine dust exposure with changes in brain blood flow in Sprague Dawley rats by using micro-positron emission tomography and elucidate the possibility of developing cerebrovascular diseases caused by fine dust. The subjects were exposured to an average fine dust (particulate matter 2.5) of 206.2 ± 7.74 to ten rats four times a day, twice a day for 90 min. Before the experiment, they were maintained at NPO to the maximize the intake of ¹⁸F-fluorodeoxy glucose(¹⁸F-FDG) and minimize changes in the ¹⁸F-FDG biomass depending on the ambient environment and body temperature of the rats. PET images were acquired in the list mode 40 min after injecting ¹⁸F-FDG 44.4 MBq into the rats tail vein using a micro-PET scanner pre and post exposure to fine dust. We found that the whole brain level of ¹⁸F-FDG standardized uptake value in rats averaged 5.21 ± 0.52 g/mL pre and 4.22 ± 0.48 g/mL post exposure to fine dust, resulting in a statistically significant difference. Fine dust was able to alter brain activity after entering the body via the lungs in various forms depending on the particle size.

• 한국산학기술학회논문지
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• 제20권7호
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• pp.78-84
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• 2019

본 연구의 목적은 간호대학생의 미세먼지에 대한 위험인식, 지식, 위험태도, 건강관리행위 간의 관계를 파악하기 위한 서술적 조사연구이다. 자료 수집은 D광역시, C도 소재 4년제 간호대학생 168명을 대상으로 실시하였다. 수집된 자료는 SPSS WIN 20.0 프로그램을 이용하여 independent t-test, one way ANOVA, Pearson correlation coefficient로 분석하였다. 본 연구결과 미세먼지에 대한 지식은 호흡기질환 유무(t=1.92, p<.001)에서 통계적으로 유의한 차이를 보였다. 미세먼지에 대한 위험태도는 호흡기질환 유무(t=2.05, p=.042), 주관적 건강상태(F=3.79, p=.012)에서 통계적으로 유의한 차이를 보였다. 미세먼지에 대한 위험인식과 지식(r=.340, p<.001), 위험태도(r=.492, p<.001), 건강관리행위(r=.354, p<.001)는 모두 유의한 양의 상관관계가 있었으며, 미세먼지에 대한 지식과 위험태도(r=.401, p<.001), 건강관리행위(r=.296, p<.001), 미세먼지에 대한 위험태도와 건강관리행위(r=.550, p<.001)도 통계적으로 유의한 양의 상관관계를 보였다. 본 연구 결과를 바탕으로 간호대학생의 미세먼지에 대한 위험인식과 지식을 높이고, 건강관리행위를 향상시키기 위한 프로그램 개발이 필요할 것이다.

• 대한의생명과학회지
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• 제20권3호
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• pp.173-179
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• 2014

Asian sand dust is known to promote various respiratory symptoms or disorders. For the prevention of harmful health effects by Asian sand dust, the best strategy is known to avoid or reduce exposure to the Asian sand dust. Several studies have shown that Korean red ginseng (RG) has anti-inflammatory and anti-allergic effects. The study aimed to clarify the effect of Korean red ginseng intake on lung inflammation responses to artificial sand dust (ASD) similar to Asian sand dust. BALB/c mice were divided into five groups (n=12) of control (saline), ovalbumin (OVA), OVA with ASD, OVA plus RG with ASD, and OVA plus dexamethasone (DEXA) with ASD. Histopathologic evaluation of lung was conducted. Interleukin (IL)-5, IL-12, interferon (IFN)-${\gamma}$, IL-13, monocyte chemotactic protein (MCP)-1, and eotaxin within bronchoalveolar lavage (BAL) fluid were measured by ELISA. OVA+ASD group significantly increased concentrations of IL-5, IL-13, MCP-1, and eotaxin (P<0.01) compared to the control. OVA+ASD+RG group showed significant decreased levels of IL-2, IL-13, MCP-1 and eotaxin (P<0.01) compared with OVA+ASD. Between RG and DEXA treatment groups, there was no significant difference in all cytokines and chemokines. The inflammatory cells were significantly decreased in treatment groups with RG or DEXA compared to OVA+ASD group. This study suggests a beneficial effect of Korean RG administration in preventing inflammation of lung resulting from Asian sand dust.