• 대한의생명과학회지
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• 제27권4호
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• pp.283-290
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• 2021

Severe acute respiratory syndrome coronavirus (SARS-CoV2) is a major coronavirus that infects humans with human Coronavirus (HuCoV)-229E, HCoV-OC43, HCoV-HKU1, HCoV-NL63, Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle east respiratory syndrome coronavirus (MERS-CoV). SARS-CoV2 is currently a global pandemic pathogen. In this study, we developed conventional RT-PCR based diagnostic system for the detection of SARS-CoV2 which is relatively inexpensive but has high stability and a wide range of users. Three conventional RT-PCR primer sets capable of forming specific band sizes by targeting the ORF1ab [232 nucleotide (nt)], E (200 nt) and N (288 nt) genes of SARS-CoV2 were developed, respectively, and it were confirmed to be about 10~100 times higher detection sensitivity than the previously reported methods. In addition, a standard positive control that can generate specific amplicons by reacting with the developed RT-PCR primers and verify the false-positiv from contamination of the laboratory was produced. Therefore, the diagnostic system that uses the RT-PCR method is expected to be used to detect SARS-CoV2.

• 대한통합의학회지
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• 제11권3호
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• pp.25-33
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• 2023

Purpose : Stabilization exercise and respiratory muscle training are used to train trunk muscles that affect postural control and respiratory function. However, there have been no studies that combine stabilization exercise and respiratory muscle training. The purpose of this study is to investigate effects of stabilization exercise with and without respiratory muscle training on respiratory function and postural sway. Methods : Fifteen healthy adults were recruited for this experiment. All the subjects performed stabilization exercise with and without respiratory muscle training. For stabilization exercise with respiratory muscle training, the subjects sat on a gym ball wearing a stretch sensor. The subjects inspire maximally as long as possible during lifting one foot off the ground, alternately for 30 seconds. The stretch sensor was placed on both anterior superior iliac spine (ASIS), and the stretch sensor was used to monitor inspiration. For stabilization exercise without respiratory muscle training, the subjects sat on a gym ball and lifted one foot off the ground, without respiratory muscle training. Kinovea program used to investigate postural sway tracking during exercise. The maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) were measured using a spirometer to investigate changes of respiratory muscle strength before and after exercise. A paired t-test was used to determine significant differences postural sway tracking, MIP, and MEP between stabilization exercise with and without respiratory muscle training. Results : There were significantly lower a distance of postural sway tracking during stabilization exercise with respiratory muscle training, compared with stabilization exercise without respiratory muscle training (p<.05). The MIP and MEP were significantly increased after stabilization exercise with respiratory muscle training compared with before stabilization exercise with respiratory muscle trianing (p<.05). Conclusion : The results of this study suggest that stabilization exercise with repiratory muscle training would be recommended to improve postural control and respiratory muscle strength.

• 대한물리치료과학회지
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• 제27권3호
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• pp.1-11
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• 2020

Background: The purpose of this study was to investigated the effects of threshold resistance inspiratory muscle training on respiratory function in chronic stroke patients. Design: Randomized Controlled Trial Methods: Eighteen patient with stroke were randomly assigned to the experimental group (n=9) and control group (n=9) all testing and training. The experimental group underwent threshold resistance inspiratory muscle training with resistance adjusted of maximal inspiratory pressure, 60 breathing a day and general physical therapy 30 minutes a day, 5 times a week for 4 weeks. The control group was taken general respiratory muscle training and general physical therapy for 4 weeks in the same way. Respiratory function, walking ability were evaluated before and after the intervention. Statistical significance of the results were evaluated by ANCOVA between control group and experimental group after intervention. Results: There was a significant increase in FVC and FEV1 in the experimental group in pulmonary function tests (p<0.05). There was a significant difference with the maximum inspiratory pressure and the maximum inspiratory flow rate between experimental and control group (p<0.05). There was no significant difference with the maximum inspiratory capacity between experimental and control group (p>0.05) but the maximum inspiratory capacity of experimental group some increased than that of control group. Conclusion: These finding gave some indications that the threshold resistance inspiratory training may benefit on pulmonary function in people with stroke, and it is feasible to be included in rehabilitation interventions with this population.

• 한국의학물리학회지:의학물리
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• 제33권4호
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• pp.136-141
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• 2022

Purpose: This study aimed to develop a breath control training system for breath-hold technique and respiratory-gated radiation therapy wherein the patients can learn breath-hold techniques in their convenient environment. Methods: The breath control training system comprises a sensor device and software. The sensor device uses a loadcell sensor and an adjustable strap around the chest to acquire respiratory signals. The device connects via Bluetooth to a computer where the software is installed. The software visualizes the respiratory signal in near real-time with a graph. The developed system can signal patients through visual (software), auditory (buzzer), and tactile (vibrator) stimulation when breath-holding starts. A motion phantom was used to test the basic functions of the developed breath control training system. The relative standard deviation of the maxima of the emulated free breathing data was calculated. Moreover, a relative standard deviation of a breath-holding region was calculated for the simulated breath-holding data. Results: The average force of the maxima was 487.71 N, and the relative standard deviation was 4.8%, while the average force of the breath hold region was 398.5 N, and the relative standard deviation was 1.8%. The data acquired through the sensor was consistent with the motion created by the motion phantom. Conclusions: We have developed a breath control training system comprising a sensor device and software that allow patients to learn breath-hold techniques in their convenient environment.

• 한국컴퓨터정보학회논문지
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• 제29권3호
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• pp.165-171
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• 2024

본 연구는 2급 응급구조사가 호흡부전 및 호흡정지 환자에게 백-밸브 마스크(BVM) 인공호흡 시 호흡량 측정기를 사용하여 적정량의 호흡량과 및 성공률을 알아보고자 한다. 연구는 2023년 12월 11일부터 12일까지 D 대학교에 재학 중인 2급 응급구조사를 대상으로 20명을 선정하여 10명은 호흡량 측정기를 이용하여 BVM 인공호흡을 교육한 실험군으로, 다른 10명은 호흡량 측정기 없이 BVM 인공호흡을 교육한 대조군으로 선정하여 2분간 인공호흡을 제공하는 실험을 하였다. 연구 결과, 대조군에서는 정확한 호흡량을 제공하지 못하였고(p=.025), 호흡 성공률 역시 실험군에서는 2분간 호흡 성공률이 높았으나 대조군에서는 유의한 차이를 보였으며(p=.001), 주관적 호흡량과 측정된 객관적 호흡량이 대조군에서 유의한 차이를 보였다(p=.010). 따라서 호흡량 측정기를 사용한 교육은 2급 응급구조사가 느끼는 주관적 호흡량을 객관적 호흡량과 일치시키고 호흡 성공률을 높여 호흡부전 및 호흡정지와 심폐소생술 시 심장정지 환자의 생존율을 높이는 데 도움이 될 것이다.

• Tuberculosis and Respiratory Diseases
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• 제76권5호
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• pp.249-249
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• 2014

• 대한통합의학회지
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• 제11권4호
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• pp.247-258
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• 2023

Purpose : This study aims to evaluate the effectiveness of a sea breeze walking program by analyzing the metabolic disease-related, immune-inflammation-related, and respiratory health-related variables of the test subjects associated with improved respiratory health. Methods : In the experiment, 30 patients with metabolic diseases were divided into an experimental group (n=15) and a control group (n=15). The experimental group walked on the Namparang-gil, Geoje trail, while the control group walked on the Hoeya-cheon, Yangsan trail. Both groups participated in the same walking program for two hours, twice a week for four weeks. Thereafter, the metabolic disease-related, immune inflammation-related, and respiratory health-related variables were measured and compared between the two groups. Results : After the four-week sea breeze walking program, in terms of changes in the metabolic disease-related variable, a statistically significant interactive effect was found in waist circumference (p<.001). The experimental group showed a significant decrease in waist circumference after the program. After the four-week sea breeze walking program, the control group showed a statistically higher increase in lactic acid (p.<05), whereas the experimental group exhibited a decrease in lactic acid. For the respiratory health-related variables, no statistically significant differences were found after the sea breeze walking program. However, the experimental group showed an increase in FEV1,while the control group showed a decrease in FEV1. For the maximum oxygen intake, no statistically significant interactive differences were found but there was a statistically significant effect in time (p<.05). The two groups exhibited an increase in maximum oxygen intake. Conclusion : After the sea breeze walking program, positive physical changes were observed in the metabolic disease-related and immune inflammation-related variables.

• 대한물리치료과학회지
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• 제25권3호
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• pp.17-24
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• 2018

Purpose: The purpose of this study was to investigate the effect of whole body vibration combined breathing resistance on lung capacity and respiratory muscle and to suggest a mediation method for improvement of respiratory function and lung function in the future. Methods: This study was a preliminary study design of two groups of 54 healthy young adults who were randomly assigned to an experimental group (n=27) with core exercise combined with respiratory resistance and whole body vibration and a control group with respiratory resistance and core exercise (n=27). All interventions consisted of 6 core exercises every 40 seconds and rest for 20 seconds. To compare the effects of intervention, we measured spirometry and respiratory muscle strength. Results: Both the experimental group and the control group showed a significant increase in Forced vital capacity (FVC) and Maximum voluntary ventilation (MVV) (p<.05). However, FEV1 and FEV1% were significantly increase only in the experimental group (p<.05). FVC, FEV1%, Maximum Inspiratory Pressure (MIP), Maximum Expiratory Pressure (MEP) showed more significant increase in the experimental group than the control group. Conclusion: These findings indicate that whole-body vibration combined breathing resistance is an effective intervention for people, with FVC, FEV1%, MIP, MEP increase.

• 한국간호교육학회지
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• 제9권1호
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• pp.17-29
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• 2003

This study investigated the degree of self-care practice to maintain the stable respiratory function and the required respiratory nursing needs upon the elderly with chronic obstructive pulmonary diseases. The research subjects were 115 elderly people over 60 years old, who were diagnosed to have chronic obstructive pulmonary diseases (the mixed type, chronic bronchitis, bronchial asthma, emphysema) and were hospitalized in 3 university hospitals in Busan or treated as outpatient, and the data was collected over the period between June 1, 2002 and September 30, 2002. In order to measure the respiratory self-care practice degree and nursing needs of the subjects, the instrument on the self-care practice and the instrument on nursing needs were developed by the researcher. The research results are as follows: 1. The mean of respiratory self-care practice degree by the subjects was 2.41 out of 4 for each clause, and the degree of practicing general management was the highest(2.70), and nutrition control(2.66), respiratory exercise(2.65), expectoration of sputum (2.63), oxygen therapy(2.60), environment control(2.50), and medication control(2.36) succeeded. 2. The degree of self-care practice had a significant difference depending on age(F=2.82, P=0.02), frequency of hospitalization(F=3.11, P=0.01), and diagnosed disease(F=15.66, P=0.00). 3. The subjects nursing needs of respiratory system were 3.07 on the average out of 4.00, and 'I want to know how to prevent the infection of respiratory system such as cold scored the highest 3.83, while the clauses like 'want to know how to face the respiratory disorder properly'(3.77) and 'want the specific explanation of the symptoms of my disease'(3.66) also had scored high points. 4. The nursing needs of the respiratory system had a significant difference depending on diagnosed disease such as mixed type of chronic obstructive pulmonary diseases, emphysema, bronchitis, and asthma (F=6.70, P=0.00). The research showed that the subjects degree of self-care practice of respiratory system was low on the whole, while the nursing needs for managing respiratory organ were relatively high. Therefore, specific education concerning the nursing of the disease and self-care upon the elderly having chronic obstructive pulmonary disease is necessary.

• 수면정신생리
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• 제16권1호
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• pp.22-27
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• 2009

Regulation of respiration differs significantly between wakefulness and sleep. Respiration during wakefulness is influenced by not only automatic control but also voluntary and behavioral control. Sleep is associated with definite changes in respiratory function. With the onset of sleep, voluntary control of ventilation that overrides automatic control during wakefulness becomes terminated. Also ventilatory response to various stimuli including hypoxemia and hypercapnia is decreased. With these reasons respiration during sleep becomes fragile and unstable so that marked hypoxemia can be happened in patients with lung disease especially during REM sleep. Obstructive sleep apnea may also be developed if upper airway resistance is increased in addition to these blunted ventilatory responses.