• Journal of Ginseng Research
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• v.39 no.2
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• pp.141-147
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• 2015

Background: Adipocytes, which are the main cellular component of adipose tissue, are the building blocks of obesity. The nuclear hormone receptor $PPAR{\gamma}$ is a major regulator of adipocyte differentiation and development. Obesity, which is one of the most dangerous yet silent diseases of all time, is fast becoming a critical area of research focus. Methods: In this study, we initially aimed to investigate whether the ginsenoside Rf, a compound that is only present in Panax ginseng Meyer, interacts with $PPAR{\gamma}$ by molecular docking simulations. After we performed the docking simulation the result has been analyzed with several different software programs, including Discovery Studio, Pymol, Chimera, Ligplus, and Pose View. All of the programs identified the same mechanism of interaction between $PPAR{\gamma}$ and Rf, at the same active site. To determine the drug-like and biological activities of Rf, we calculate its absorption, distribution, metabolism, excretion, and toxic (ADMET) and prediction of activity spectra for substances (PASS) properties. Considering the results obtained from the computational investigations, the focus was on the in vitro experiments. Results: Because the docking simulations predicted the formation of structural bonds between Rf and $PPAR{\gamma}$, we also investigated whether any evidence for these bonds could be observed at the cellular level. These experiments revealed that Rf treatment of 3T3-L1 adipocytes downregulated the expression levels of $PPAR{\gamma}$ and perilipin, and also decreased the amount of lipid accumulated at different doses. Conclusion: The ginsenoside Rf appears to be promising compound that could prove useful in antiobesity treatments.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.12 no.4
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• pp.109-119
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• 2017

As advancement into global markets becomes increasingly important, there are increasing interests in high-tech companies' export. This study is an empirical investigation of the determinants of high-tech companies' export in the Daegu region seen from a resource-based perspective with focuses on organizational resources and innovative capabilities. The empirical analysis revealed that the export determinants hold truer for high-tech companies compared to companies overall, and that high-tech companies' key export determinants include organizational age as a organizational resource and international intellectual property rights (IPRs) as an innovative capability. In this sense, policies to promote high-tech companies' export should be designed to support high-tech companies that have a relatively longer history and international IPRs. The results also suggest that in the working level high-tech companies should establish their internal capabilities from a resource-based perspective, for example history and experience in their fields and international IPRs, rather than trying to target global markets from the beginning as born-global companies do.

• Journal of the Korean Chemical Society
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• v.60 no.5
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• pp.327-341
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• 2016

This study explores the effective visual resources in the “regularity in chemical reactions” unit of ninth grade science textbooks (2009 revised version). The frequency and role of visual resources were initially examined, and the students’ perceptions of visual resources were investigated. The results of the analysis represented the learning material presentation (68%), motivational categories (14%), guide to inquiry procedures (9%), and inquiry results and summaries (8%). According to the investigation of the students’ perceptions of visual resources, the most effective visual resource for motivation is a photograph depicting physical and chemical changes, such as in bread baking and the most effective for learning material presentations in mass conservation, definite proportion, and stoichiometric concept units were a cartoon, graph, and formula representing stoichiometric phenomena, respectively. The most effective resource for guide to inquiry (experimental) procedures were photographs of both instruments and sequential experiment processes; and in the inquiry results and summary category, incomplete tables and graphs for students to work on themselves. The aims of this research are to increase the usefulness of visual resources in the teaching-learning activity and provide informative supplements for the development and improvement of visual resources, according to the students’ perceptions.

• Journal of Power System Engineering
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• v.20 no.4
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• pp.44-51
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• 2016

An investigation on reliability of reanalysis wind data was conducted using the met mast wind data at four coastal regions, Jeju Island. Shinchang, Handong, Udo and Gangjeong sites were chosen for the met mast sites, and ERA-Interim and MERRA reanalysis data at two points on the sea around Jeju Island were analyzed for creating Wind Statistics of WindPRO software. Reliability of reanalysis wind data was assessed by comparing the statistics from the met mast wind data with those from Wind Statistics of WindPRO software. The relative error was calculated for annual average wind speed, wind power density and annual energy production. In addition, Weibull wind speed distribution and monthly energy production were analyzed in detail. As a result, ERA-Interim reanalysis data was more suitable for wind resource assessment than MERRA reanalysis data.

• Journal of the Korean Home Economics Association
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• v.44 no.4 s.218
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• pp.23-38
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• 2006

The purpose of this study was to investigate the strengths of single-parent families and the related variables based on the family strength approach. The major findings were as follows. First, good communication, family bond, children's adjustment and coping ability were characteristics of single-parent family strengths. Secondly, strengths of single-parent family were related to income and period of becoming a single-parent family. Thirdly, single parents who had a higher level of personal resources such as high self-esteem and economic stability perceived a higher level of family strengths. Fourth, single parents who had a higher level of social support perceived a higher level of family strength. Fifth, there was no interaction effect between personal resource and social resource on single-parent family strengths. Last, both personal and social resources had effects on the strength of single- parent family. Especially personal resource and self-esteem were the most important variables and had a strong influence on single-parent family strengths. The results of this study have important implications for theory, research and practice. Research on the strengths of the Korean single-parent family is new and more extensive investigation is required.

• Journal of the Korean Solar Energy Society
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• v.37 no.2
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• pp.1-11
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• 2017

The investigation on reliability of ERA-Interim reanalysis wind data was conducted using wind data from the five met masts measured at inland and coastal areas, Jeju island. Shinchang, Handong, Udo, Susan and Cheongsoo sites were chosen for the met mast location. ERA-Interim reanalysis data at onshore and offshore twenty points over Jeju Island were analyzed for creating Wind Statistics using WindPRO software. Reliability of ERA-Interim reanalysis wind data was assessed by comparing the statistics from the met mast wind data with those predicted at the interest point using the Wind Statistics. The relative errors were calculated for annual average wind speed and annual energy production. In addition, the trend of the error was analyzed with distance from met mast. As a result, ERA-Interim reanalysis wind data was more suitable for offshore wind resource assessment than onshore.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.2
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• pp.299-306
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• 2001

As a part of basic investigation for utilization of canned food processing by-products, a food components of the canned oyster processing waste water such as boiled and released water(BRW), wash water(WW) were investigated and compared with hot-water extracts from oyster. From the results of measuring heavy metal conte수, viable cells and coliform group, the canned oyster processing waste waters might not invoke health risk in using food resource. The contents of taste compounds (free amino acids, ATP related compounds, TMA (O) and total creatinine) of BRW and WW accounted for about 254% and 95%, respectively, in comparison with those of control (hot-water extract from oyster). The BRW showed a very high content of salt in comparing to the WW and control. In descending order, the values of whiteness index was WW, control and BRW. Sensory scores for color, oyster flavor intensity and saline taste were not significantly different between WW and control. But, BRW had the highest score in oyster flavor intensity, while had the lowest score in color and saline taste. But, the color and saline taste of BRW might be able to control by some pretreatment (concentration and drying in mild condition, desalination and recipe control etc). These results indicated that BRW and WW generated from various step during canned oyster processing could be a potential food resource by controlling of saline taste and color intensity.

• Korean Journal of Veterinary Service
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• v.35 no.1
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• pp.63-67
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• 2012

An 8-months-old young Maltese bitch was presented for investigation of anorexia and occasional vomiting. The body weight was 2 kg. Abdominal sonography demonstrated abnormal enlargement of uterus. The dog had been clinically and pathologically examined. Also, ovariohystectomy was performed. Staphylococcus aureus was identified in the pus-like materials of the uterine lumen. This case was confirmed as pyometra induced by Staphylococcus aureus. Gross examination of the dissected uterus revealed enlarged uterine horn, which had yellowish or brownish pus-like materials in the lumen. Also, there was several segments formation between the enlarged areas of left and right uterine horns. Histopathologically, endometritis and necrosis were present in uterine wall. The bitch made a complete recovery following an ovariohystectomy. This case was spontaneous pyometra induced by Staphylococcus species. On our knowledge, this is a very rare report of pyometra occurrence in young dog and Staphylococcus species-induced pyometra. This study may provide a valuable data on the study of canine pyometra.

• Journal of the Korean Society of Marine Environment & Safety
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• v.14 no.3
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• pp.205-210
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• 2008

In recent years, the crisis of energy is growing seriously and also the contamination of ecology has been reverberated as international problem. The social concern about energy crisis has been growing for the last several years and also the interest in new and renewable energy has been increased. The probability of wind power resource over Saemangeum is reviewed with the data of Gunsan weather station. Through this study, it is cleared that the Saemangeum area has fluent wind power source to design the wind farm in Korea. According to calculation results, it is possible to predict the wind velocity density around the Saemangeum area using the shape factor as a parameter.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.3
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• pp.1474-1480
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• 2013

This study attempted to estimate construction costs in accordance with the resource-based cost estimation (unit cost price) system by diameter for TBM method, and analyzed the direct cost and the total cost. Based on such figures, this study performed a regression analysis and proposed a model for an equation for estimating construction costs. model for the resource-based cost estimation (unit cost price) system classified by diameter for TBM method proposed by this study can be effectively applied to business planning, preliminary investigation, feasibility study, construction cost estimations in the early design stages.