• Journal of Korea Multimedia Society
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• v.10 no.12
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• pp.1679-1686
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• 2007

In this paper, we introduce the sharable and reusable learning objects which are suitable for XML Web services in e-learning systems. These objects are extracted from the principles of pedagogical paradigms for reusable learning units. We call them LIO (Learning Item Object) objects. Existing models, such as Web-hosted and ASP-oriented service model, are difficult to cooperate and integrate among the different kinds of e-learning systems. So we developed the LIO objects that are suitable for XML Web services. The reusable units that are extracted from pedagogical paradigms are tutorial item, resource, case example, simulation, problems, test, discovery and discussion. And these units correspond to the LIO objects in our learning object model. As a result, the proposed model is that learner and instruction designer should increase the power of understanding about learning contents that are based on pedagogical paradigms. By using XML Web services, this guarantees the integration and interoperation of the different kinds of e-learning systems in distributed environments and so educational organizations can expect the cost reduction in constructing e-learning systems.

• Journal of Korea Technology Innovation Society
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• v.8 no.spc1
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• pp.476-498
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• 2005

The purpose of this study is to development of venture business curriculum by FGI interview to venture CEO and related field employer and suggest to venture related structure of liberal art, major part of undergraduate and graduate school. Research methods are 2 step interview with 325 venture business CEO and related employer. They selected practical course to motivate venture entrepreneurship among 3 subsidiary (entrepreneurial condition, psychology of entrepreneur, competency of entrepreneurial technology, competency of entrepreneurial knowledge, competency of managing growing business). Major findings are as follows; the selected course category of entrepreneurial condition of liberal art are venture mind and entrepreneurship, venture biz and spearhed industry. The selected course category of psychology of entrepreneur are leadership, personal relationship, and creativity, negotiation skill, etc. The selected course category of competency of entrepreneurial technology are venture technology, introduction to technology trends. The selected course category of competency of entrepreneurial knowledge are biz validity, entrepreneurship, the discovery of business opportunity, utilization of monetary resource etc. The selected course category of competency of managing growing business are operating strategy of venture business, service marketing and technical innovation and technology management.

• Journal of Computing Science and Engineering
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• v.10 no.3
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• pp.85-94
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• 2016

We propose a model-based method for information alignment using educational standards as a case study. Discrepancies and inconsistencies in educational standards across different states/cities hinder the retrieval and sharing of educational resources. Unlike existing educational standards alignment systems that only give binary judgments (either "aligned" or "not-aligned"), our proposed system classifies each pair of educational standard statements in one of seven levels of alignments: Strongly Fully-aligned, Weakly Fully-aligned, Partially-$aligned^{***}$, Partially-$aligned^{**}$, Partially-$aligned^*$, Poorly-aligned, and Not-aligned. Such a 7-level categorization extends the notion of binary alignment and provides a finer-grained system for comparing educational standards that can broaden categories of resource discovery and retrieval. This study continues our previous use of mathematics education as a domain, because of its generally unambiguous concepts. We adopt a materialization pattern (MP) model developed in our earlier work to represent each standard statement as a verb-phrase graph and a noun-phrase graph; we align a pair of statements using graph matching based on Bloom's Taxonomy, WordNet, and taxonomy of mathematics concepts. Our experiments on data sets of mathematics educational standards show that our proposed system can provide alignment results with a high degree of agreement with domain expert's judgments.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.2
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• pp.360-372
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• 2020

Objective: Specific genomic sites can be recognized and permanently modified by genome editing. The discovery of endonucleases has advanced genome editing in pigs, attenuating xenograft rejection and cross-species disease transmission. However, off-target mutagenesis caused by these nucleases is a major barrier to putative clinical applications. Furthermore, off-target mutagenesis by genome editing has not yet been addressed in pigs. Methods: Here, we generated genetically inheritable α-1,3-galactosyltransferase (GGTA1) knockout Yucatan miniature pigs by combining transcription activator-like effector nuclease (TALEN) and nuclear transfer. For precise estimation of genomic mutations induced by TALEN in GGTA1 knockout pigs, we obtained the whole-genome sequence of the donor cells for use as an internal control genome. Results: In-depth whole-genome sequencing analysis demonstrated that TALEN-mediated GGTA1 knockout pigs had a comparable mutation rate to homologous recombination-treated pigs and wild-type strain controls. RNA sequencing analysis associated with genomic mutations revealed that TALEN-induced off-target mutations had no discernable effect on RNA transcript abundance. Conclusion: Therefore, TALEN appears to be a precise and safe tool for generating genomeedited pigs, and the TALEN-mediated GGTA1 knockout Yucatan miniature pigs produced in this study can serve as a safe and effective organ and tissue resource for clinical applications.

• The Journal of the Korea Contents Association
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• v.9 no.2
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• pp.326-338
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• 2009

In this paper, we argue that characteristics of ubiquitous business are different from those of e-business or m-business. We have developed a u-business model development framework incorporating the concept of value co-creation experiences, which is a core of the ubiquitous business paradigm. The framework of u-business model development presented in this paper consists of eight steps such as defining of domain, discovery of opportunity nucleus, defining of potential co-creation experience environment, deriving candidates of u-business services, selecting u-business killer services, defining value propositions of u-business killer services, defining u-business killer service offerings, and drawing a resource map of u-business killer services. The proposed u-business model development framework offers useful guidelines for practitioners to develop successful u-business models under a ubiquitous business paradigm.

• Journal of the Korean Magnetic Resonance Society
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• v.11 no.2
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• pp.73-84
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• 2007

MTH1821 (UniProtKB/TrEMBL ID O27849) is a 96-residue hypothetical protein from the open reading frame of Methanobacterium thermoautotrophicum H one of the target organisms of structural genomics pilot project. Proteins which contain conserved sequence compared with MTH1821 have not been discovered yet and the functional and structural information for MTH1821 is not available. Here, we present the sequence-specific backbone resonance using multidimensional heteronuc1ear NMR spectroscopy and propose the secondary structure using GetSBY software. The backbone resonances of N, HN, $C_{\alpha}$, $C_{\beta}$, CO and $H_{\alpha}$ which are necessary for a prediction of secondary structure by GetSBY were assigned about 98% (557/568). The secondary structure of MTH1821 confirmed that it is comprised of four strand regions and two helical regions. This report will provide a valuable resource for the calculation solution structure of MTH1821 and for the other hypothetical protein that is targeted for structural-based functional discovery.

• Proceedings of the Korea Information Processing Society Conference
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• 2007.05a
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• pp.1163-1166
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• 2007

핸드오버가 발생하는 이동망 환경에서 주요 이슈 중 하나는 핸드오버 후 MN(Mobile Node)의 트래픽이 전송될 새로운 경로 상에 자원 재예약을 위한 지연 시간을 최소화하는 것이다. 이를 위해, 데이터 전달 경로가 변경된 경로에서만 자원예약 시그널링이 이루어지도록 CRN(Crossover Node)을 발견하는 것이 중요하다. 이동망 환경에서 자원 재예약을 위한 CRN은 SID(Session ID)를 이용하여 발견될 수 있다. 그러나 HMIPv6 네트워크에서 MAP(Mobility Anchor Point)과 HA(Home Agent)간 군집(Aggregate) 자원 예약이 이루어진 경우에서는 SID를 이용하여 CRN을 발견할 수 없다. 왜냐하면, MN의 핸드오버 후, 종단간 SID는 동일할지라도 이전 MAP과 HA간 설립된 세션의 군집 SID가 새로운 MAP과 HA간 설립된 세션의 군집 SID와 다르기 때문이다. 이에, 본 논문에서는 HMIPv6 네트워크에서의 CRN 발견방안을 제안한다. 제안하는 방안에서는 시그널링 메시지에 이전 군집 세션 정보를 포함하여 전달함으로서 시그널링 메시지가 목적지까지 도달하기 전에 CRN이 발견될 수 있도록 하였다. 제안하는 방안은 군집 자원예약이 갖는 시그널링 및 플로우별 상태 정보 감소 효과를 그대로 유지하면서, MN의 핸드오버 후, 자원 재예약을 위한 지연 시간을 단축시킴으로서 통신 성능을 향상 시킬 수 있을 것으로 기대된다.

• Journal of Ecology and Environment
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• v.33 no.2
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• pp.95-103
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• 2010

The archipelago in the southwest sea, Korea, was registered as Shinan Dadohae Biosphere Reserve by United Nations Educational, Scientific and Cultural Organization Man and the Biosphere (UNESCO MAB) on May 26, 2009. This study was conducted to determine a method of reconciling natural and anthropogenic processes and to enable sustainable development in the vicinity of the Shinan Dadohae Biosphere Reserve (SDBR). To accomplish this, the characteristics of SDBR with respect to biodiversity and cultural diversity were evaluated. In addition, a management plan regarding the wise use of the SDBR was developed while focusing on four parts: cultural support to induce motivation for native conservation and development; development and specification of fisheries and cultivation based on local community systems; restructuring of marine food products and resource transporting systems; activation and discovery of indigenous knowledge to enable networking between local residents, academia and the UNESCO-international society.

• Journal of the Korean Society for information Management
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• v.21 no.3
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• pp.99-123
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• 2004

Traditionally. theses and dissertations have been extremely underutilized information sources due to their lack of physical availability. The development of electronic theses and dissertations system will provide the opportunity for theses and dissertations to be recognized as a basic channel for the dissemination of research findings and an essential resource in the discovery process. In digital environment. many universities and libraries throughout the world are now making digitized versions of traditional(print) dissertations available online. The purpose of this paper is to analyze the current theses and dissertations management system based on web questionaries and survey of home pages. and to suggest a standardized theses and dissertation management model in Korea.

• 한국균학회소식:학술대회논문집
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• 2014.10a
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• pp.23-23
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• 2014

There are many yeast strains have been discovered for industrial usage in global scale. In the point of view for the alcoholic fermentation performance and producing alcoholic beverage products, recently many countries have known about the importance of microorganisms as a valuable resource. Discovered with well performed yeasts have potential industrial application in diverse ways such as foods, beverages, cosmetics, pharmaceutical functions, and so on. In Korea, the yeast research has not been sufficiently performed especially for distilled spirits industry. As a result, not so little manufacturers use exotic yeasts from overseas even included the expensive royalties. Besides of those, to produce distilled spirits, many manufacturers do not use specialized yeast for distilled spirits. Distiller's characterized yeasts such as whisky, brandy, vodka, Japanese shochu and awamori, are all well-known industrialized. For decades, the distillers, except us, have selected, developed, and practised yeasts in accordance with distilled spirits characters. This study is about selection and industrial application of yeasts for the Korean pot distilled spirits. Finally 7 yeast strains were selected among over 1,000 yeasts from the traditional Nuruks, through the essential related tests based on brewing and distilling science. The selected yeasts show the appropriate characteristics of distilled spirits. The result of this study could help our distilled spirits industry be activated and stand independent from the exotic microbes.