• Title/Summary/Keyword: Resistant performance

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An Experimental Study on Fire-Resistant Boom (내화용 오일붐의 내화성에 대한 실험적 연구)

  • Yu J.S.;Sung H.G.;Oh J.H.
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.3 no.2
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    • pp.25-32
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    • 2000
  • Fire-resistant boom is one of the most important facilities in in situ homing of spilled oil. Thermal response of a fire-resistant boom to turning is experimentally investigated in this paper by using an electric furnace and a burning test facility. This test facility is composed of a test tank, a fire boom, a hood for inhaling smoke, an incinerator for burning up gases and thermocouples, etc. Thereby a systematic method of approach in small laboratory scale is developed to study the performance of a fire-resistant boom. Burning test is carried out for the fire boom model which has been developed through the present study. It is shown that the present fire boom model has capability to withstand the high temperature around 800℃ and high rate of heat flux on it due to homing. For more realistic experimental environments, larger dimensions in devices and longer time in experiments are recommended in near future.

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The Stability, and Efficacy Against Penicillin-Resistant Enterococcus faecium, of the Plectasin Peptide Efficiently Produced by Escherichia coli

  • Chen, Xin;Wen, Yaoan;Li, Ling;Shi, Jiawei;Zhu, Zhe;Luo, Yuwen;Li, Yun;Chen, Rui
    • Journal of Microbiology and Biotechnology
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    • v.25 no.7
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    • pp.1007-1014
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    • 2015
  • Plectasin, the first defensin extracted from a fungus (the saprophytic ascomycete Pseudoplectania nigrella), is attractive as a prospective antimicrobial agent. The purpose of this study was to establish a bacterium-based production system and evaluate the antimicrobial activity of the resulting plectasin. A gene encoding plectasin, with the codon preference of Escherichia coli, was optimized based on its amino acid sequence, synthesized using genesplicing with overlap extension PCR, and inserted into the expression vector pGEX-4T-1. The fusion protein was expressed in the soluble fraction of E. coli and purified using glutathione Stransferase affinity chromatography. Plectasin was cleaved from the fusion protein with thrombin and purified by ultrafiltration. The purified plectasin showed strong, concentrationdependent antimicrobial activity against gram-positive bacteria, including antibiotic-resistant bacteria, especially penicillin-resistant Enterococcus faecium. This antimicrobial activity was equal to chemically synthesized plectasin and was maintained over a wide range of pH and temperatures. This soluble recombinant expression system in E. coli is effective for producing plectasin at a relatively lower cost, and higher purity and efficiency than prior systems, and might provide a foundation for developing a large-scale production system. Overall, plectasin shows potential as a novel, high-performance, and safe antibiotic for the treatment of refractory diseases caused by drug-resistant bacterial strains.

External Validation of Carbapenem-Resistant Enterobacteriaceae Acquisition Risk Prediction Model in a Medium Sized Hospital (중규모 종합병원 대상 카바페넴 내성 장내세균속균종(Carbapenem-resistant Enterobacteriaceae) 획득위험 예측모형의 외적타당도 평가)

  • Seo, Su Min;Jeong, Ihn Sook
    • Journal of Korean Academy of Nursing
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    • v.50 no.4
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    • pp.621-630
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    • 2020
  • Purpose: This study was aimed to evaluate the external validity of a carbapenem-resistant Enterobacteriaceae (CRE) acquisition risk prediction model (the CREP-model) in a medium-sized hospital. Methods: This retrospective cohort study included 613 patients (CRE group: 69, no-CRE group: 544) admitted to the intensive care units of a 453-beds secondary referral general hospital from March 1, 2017 to September 30, 2019 in South Korea. The performance of the CREP-model was analyzed with calibration, discrimination, and clinical usefulness. Results: The results showed that those higher in age had lower presence of multidrug resistant organisms (MDROs), cephalosporin use ≥ 15 days, Acute Physiology and Chronic Health Evaluation II (APACHE II) score ≥ 21 points, and lower CRE acquisition rates than those of CREP-model development subjects. The calibration-in-the-large was 0.12 (95% CI: - 0.16~0.39), while the calibration slope was 0.87 (95% CI: 0.63~1.12), and the concordance statistic was .71 (95% CI: .63~.78). At the predicted risk of .10, the sensitivity, specificity, and correct classification rates were 43.5%, 84.2%, and 79.6%, respectively. The net true positive according to the CREP-model were 3 per 100 subjects. After adjusting the predictors' cutting points, the concordance statistic increased to .84 (95% CI: .79~.89), and the sensitivity and net true positive was improved to 75.4%. and 6 per 100 subjects, respectively. Conclusion: The CREP-model's discrimination and clinical usefulness are low in a medium sized general hospital but are improved after adjusting for the predictors. Therefore, we suggest that institutions should only use the CREP-model after assessing the distribution of the predictors and adjusting their cutting points.

Characteristics and Development Trends of Heat-Resistant Composites for Flight Propulsion System (비행체 추진기관용 내열 복합재의 특성 및 개발 동향)

  • Hwang, Ki-Young;Park, Jong Kyoo
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.47 no.9
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    • pp.629-641
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    • 2019
  • In order to limit the temperature rise of the structure to a certain level or less while maintaining the aerodynamic shape of solid rocket nozzle by effectively blocking a large amount of heat introduced by the combustion gas of high temperature and high pressure, the heat-resistant materials such as C/C composite having excellent ablation resistance are applied to a position in contact with the combustion gas, and the heat-insulating materials having a low thermal diffusivity are applied to the backside thereof. SiC/SiC composite, which has excellent oxidation resistance, is applied to gas turbine engines and contributes to increase engine performance due to light weight and heat-resistant improvement. Scramjet, flying at hypersonic speed, has been studying the development of C/SiC structures using the endothermic fuel as a coolant because the intake air temperature is very high. In this paper, characteristics, application examples, and development trends of various heat-resistant composites used in solid rocket nozzles, gas turbine engines, and ramjet/scramjet propulsions were discussed.

Effect of Non-starch Polysaccharides and Resistant Starch on Mucin Secretion and Endogenous Amino Acid Losses in Pigs

  • Morel, Patrick C.H.;Melai, J.;Eady, S.L.;Coles, G.D.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.11
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    • pp.1634-1641
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    • 2005
  • Generally, dietary fibre (DF) includes lignin, non-starch polysaccharides (NSP) and resistant starch (RS). In monogastric species, low levels of dietary fibre in the diet are associated with various diseases and high levels reduce nutrient digestibilities. In this study, the effects of different types and levels of NSP (soluble: $\beta$-glucan, insoluble cellulose) and resistant starch on mucin secretion and endogenous nitrogen and amino acid losses in pigs were investigated. A total of 25 five-week-old weaner pigs (9.5 kg${\pm}$1.5 kg), were randomly allocated to each of five experimental diets. Different levels of purified barley $\beta$-glucan (BG) extract (5 or 10% of $Glucagel^{(R)}$ $\beta$-glucan, providing 4 or 8% of BG in the diet), and resistant starch (RS) (8.3 or 16.6% of Hi-$Maize^{TM}$, providing 5 or 10% RS in the diet) were substituted for wheat starch in a purified diet in which enzymatically-hydrolysed casein was the sole source of protein. The diets were fed for 21 days. No statistically significant difference between treatments (p>0.05) was observed for growth performance and organs weights. No difference in ileal starch digestibility was observed between pigs on the cellulose or $\beta$-glucan diets. However, as the level of resistant starch in the diet increased the ileal starch digestibility decreased (p<0.05). The inclusion of resistant starch in the diet (5 or 10%) did not increase mucin production when compared with the cellulose-only diet. However, as the level of beta-glucan in the diet increased, both crude mucin in the digesta dry matter and per kg dry matter intake increased (p<0.05). Pigs fed the diet containing 8% of beta-glucan had higher endogenous loss flow than those fed the diets including 5 or 10% of resistant starch or 4% of $\beta$-glucan. In conclusion, dietary inclusion of resistant starch increased the level of starch reaching the large intestine without any effect on mucin secretion, or endogenous nitrogen or amino acid losses content in the small intestine. The addition of $\beta$-glucan to a diet containing cellulose increases both mucin secretion and endogenous amino acid and nitrogen losses in the small intestine.

Uncertainty and Performance of Infection Control in Caregivers of Vancomycin-Resistant Enterococci Patients (반코마이신 내성 장구균 환자 보호자의 질병 불확실성과 감염관리 수행)

  • Lee, Eunsuk
    • The Journal of the Korea Contents Association
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    • v.15 no.6
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    • pp.346-357
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    • 2015
  • Purpose: This descriptive study was to examine uncertainty and performance of infection control in the VRE patients' caregivers. Methods: The participants were 82 caregivers who involved with the VRE patients care in D tertiary hospital in D metropolitan city. Data were analyzed with number, percentage, t-test, and ANOVA using SPSS/Win 21.0. Results: The participants' uncertainty was 56.99 and performance of infection control was 35.09. Performance of infection control was significantly different by age (F=121.38, p<.001), education (F=102.77, p<.001), relationship with the patient (F=17.80, p<.001), hours of caring per day (t=3.14, p=.002), and type of family (t=-8.65, p<.001). There was a significant negative correlation between participants' uncertainty and performance of infection control (r=-.96, p<.001). Conclusion: The results of the study will be used to develop nursing intervention program and standard protocol for infection control for the VRE patients' caregivers.

Base isolation performance of a cone-type friction pendulum bearing system

  • Jeon, Bub-Gyu;Chang, Sung-Jin;Kim, Sung-Wan;Kim, Nam-Sik
    • Structural Engineering and Mechanics
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    • v.53 no.2
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    • pp.227-248
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    • 2015
  • A CFPBS (Cone-type Friction Pendulum Bearing System) was developed to control the acceleration delivered to a structure to prevent the damage and degradation of critical communication equipment during earthquakes. This study evaluated the isolation performance of the CFPBS by numerical analysis. The CFPBS was manufactured in the shape of a cone differenced with the existing FPS (Friction Pendulum System), and a pattern was engraved on the friction surface. The natural frequencies of the CFPBS were evaluated from a free-vibration test with a seismic isolator system consisting of 4 CFPBS. To confirm the earthquake-resistant performance, a numerical analysis program was prepared using the equation of the CFPBS induced from the equations of motion. The equation reported by Tsai for the rolling-type seismic isolation bearings was proposed to design the equation of the CFPBS. Artificial seismic waves that satisfy the maximum earthquake scale of the Korean Building Code-Structural (KBC-2005) were created and verified to review the earthquake-resistant performance of the CFPBS by numerical analysis. The superstructural mass of the CFPBS and the skew angle of friction surface were considered for numerical analysis with El Centro NS, Kobe NS and artificial seismic waves. The CFPBS isolation performance evaluation was based on the numerical analysis results, and comparative analysis was performed between the results from numerical analysis and simplified theoretical equation under the same conditions. The validity of numerical analysis was verified from the shaking table test.

An Experimental Study on Performance of Heatproof Silicon at the Connector of Boiler Exhaust Tube (배기통과 가스보일러 접속부의 내열실리콘 성능에 관한 실험적 연구)

  • Leem, Sa-Hwan;Lee, Jong-Rark;Kim, Cheol-Jin;Han, Gwi-Ho;Kim, Yong-Joo;Kim, Hee-Soo;Jang, Won-Suk;Lim, Cheong-Hwan
    • Journal of the Korean Institute of Gas
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    • v.11 no.4
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    • pp.91-97
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    • 2007
  • Recently, during the past five years, accidents of gas boiler using city gas have occurred 7.4 times more than those which use LP gas. The number of accidents has increased since the use of city gas boilers has increased. These boiler accidents resulted in 87% death from poisoning of CO, and casualty of the accidents was 4.3 times more than that of other types of accident. Hence this study makes the cause of accidents clear by separation the exhaust tube which is the cause of CO poisoning. Also, this study will establish the safety of heat-resistant silicon through testing the performance of heat-resistant silicon. The experiment showed that common silicon started hardening at $56^{\circ}C$ while the heat-resistant silicon did not begin carbonization until $606^{\circ}C$. Besides at the temperature of $150^{\circ}C$ which is the normal temperature of exhaust tube, common silicon leaked on the pneumatic test after deterioration, but the heat-resistant silicon maintained its original property. With these results, we judge that we can reduce the casualty by CO poisoning if we use the heat-resistant silicon to the connector of he exhaust tube.

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A Study on the Characterization of Intrinsic Flame Retardant and Heat Resistant Sulfur-Bridged Heterocyclic Polymers (본질적 난연 및 내열성 헤테로환식 폴리머의 특성에 관한 연구)

  • Young-Goo Kang;Hong Kim;Ho-Suk Ryu
    • Journal of the Korean Society of Safety
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    • v.12 no.3
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    • pp.173-178
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    • 1997
  • The intrinsic flame retardant and heat resistant polymers such as PQXS [poly( quinoxaline )sulfide], PIQS [poly(isoquinoline)sulfide] and PQS [poly(quinoline)sulfide] were synthesized from 2, 3-dichloroquinoxaline, 1, 3-dichloroisoquinoline and 4, 7-dichloroquinoline. They were characterized by FT-IR, UV/Vis spectroscopy, DTA and elemental analysis. The melting point above $350^{\circ}C$ of the polymers show higher than that of the heat resistant PPS polymer(mp. $295^{\circ}C$), In the LOI test, the polymers exhibit an intrinsically high flame retardant property having the LOI values in the range of 41~42. The vertical burning test for the polymers also show an UL 94 V-0 performance.

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Breeding of Burley Tobacco KB 110 Resistant to PVY and Black Shank and its Agromomic Characteristics (감자바이러스 Y 및 역병 저항성 연초 버어리종 신품종 KB 110의 육성 및 농경적 특성)

  • 정석훈;최상주;조천준;조명조
    • Journal of the Korean Society of Tobacco Science
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    • v.19 no.2
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    • pp.83-91
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    • 1997
  • The vein-necrosis strain or potato virus Y (PVY-Vff) and black shank (Phytophlhora parasitica roar. nicotianae) causes severe damage on burley tobacco(Wicotiana tabacum L.) in Korea, A new burley tobacco resistance to PVY and black shank, KB 110, was developed by Korea Ginseng and Tobacco Research Institute. It was developed from the cross of Burley 21 with TC 591 in 1990, and was backrossed to Burley 21 in the following season. TC 591 has resistance to PVY and moderate resistance to race 0 of black shank, but it is susceptible to tobacco mosaic vim (TMV). KB 110 was evaluated for its resistance to PVY, TMV and black shank in the greenhouse and at fields for preliminary and performance trials. KB 110 which has secreting glandular trichomes was resistant to PVY-VN, TW and black shank. It had an erect growth habit and two more leaves per plant than that of Burley 21, and matures two to three days later. It yielded approximately 3 percent more cured leaf than the standard cultivar Burley 21, but other plant characteristics were very similar to those of Burley 21. It had acceptable standards for chemical and physical characteristics of lured leaf on regional farm test in 1995-1997. KB 110 produced average yields of good quality tobaccos and was appeared to be resistant to PVY inwhere occurrence of the virus are severe chronic at burley growing area.

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