• 동의생리병리학회지
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• 제23권6호
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• pp.1226-1233
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• 2009

Common cold occurs frequently and occupies an important position in medical treatment however obvious treatment is not suggested. There has been no agreement of pattern identification for common cold in oriental medicine. The purpose of this study is to develop a standard instrument of pattern identification for common cold which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 9 oriental respiratory internal medicine professors of 11 oriental medical colleges nationwide. The experts attended 3 consultation meetings and discussed developing the instrument, and we also took professional advices by e-mail. The results were as follows; First, we divided the pattern identification of common cold into nine pattern: Wind-cold type, Wind-heat type, Contain summerheat type, Contain dampness type, Qi deficiency type, Blood deficiency type, Yang deficiency type, Yin deficiency type, Influenza. Second, we got the mean weights to each symptom of nine pattern identification which had been scored on a 5-point scale - ranging from 0 to 4 by the 9 experts. Third, we made out the Korean instrument of the pattern identification for common cold. It was composed self reporting questionnaire and researcher reporting questionnaire. Though this study is not proved about validity, reliability, the instrument of pattern identification for common cold is meaningful and expected to be applied to the subsequent research. And also, we hope to improve the instrument and make up for this study through various research and discussion.

• Geomechanics and Engineering
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• 제17권1호
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• pp.47-56
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• 2019

Crossing (X-type) flaws are commonly encountered in rock mass. However, the crack coalescence and failure mechanisms of rock mass with X-type flaws remain unclear. In this study, we investigate the compressive failure process of rock-like specimens containing two X-type flaws aligned in the loading direction. For comparison purposes, compressive failure behavior of specimens containing two aligned single flaws is also studied. By examining the crack coalescence behavior, two characteristics for the aligned X-type flaws under uniaxial compression are revealed. The flaws tend to coalesce by cracks emanating from flaw tips along a potential path that is parallel to the maximum compressive stress direction. The flaws are more likely to coalesce along the coalescence path linked by flaw tips with greater maximum circumferential stress if there are several potential coalescence paths almost parallel to the maximum compressive stress direction. In addition, we find that some of the specimens containing two aligned X-type flaws exhibit higher strengths than that of the specimens containing two single parallel flaws. The two underlying reasons that may influence the strengths of specimens containing two aligned X-type flaws are the values of flaw tips maximum circumferential stresses and maximum shear stresses, as well as the shear crack propagation tendencies of some secondary flaws. The research reported here provides increased understanding of the fundamental nature of rock/rock-like material failure in uniaxial compression.

• Journal of Microbiology and Biotechnology
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• 제28권9호
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• pp.1554-1562
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• 2018

The type I interferons (IFNs) play a vital role in activation of innate immunity in response to viral infection. Accordingly, viruses have evolved to employ various survival strategies to evade innate immune responses induced by type I IFNs. For example, hepatitis E virus (HEV) encoded papain-like cysteine protease (PCP) has been shown to inhibit IFN activation signaling by suppressing K63-linked de-ubiquitination of retinoic acid-inducible gene I (RIG-I) and TANK-binding kinase 1 (TBK1), thus effectively inhibiting down-stream activation of IFN signaling. In the present study, we demonstrated that HEV inhibits polyinosinic-polycytidylic acid (poly(I:C))-induced $IFN-{\beta}$ transcriptional induction. Moreover, by using reporter assay with individual HEV-encoded gene, we showed that HEV methyltransferase (MeT), a non-structural protein, significantly decreases RIG-I-induced $IFN-{\beta}$ induction and $NF-{\kappa}B$ signaling activities in a dose-dependent manner. Taken together, we report here that MeT, along with PCP, is responsible for the inhibition of RIG-I-induced activation of type I IFNs, expanding the list of HEV-encoded antagonists of the host innate immunity.

• Reproductive and Developmental Biology
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• 제30권1호
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• pp.27-34
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• 2006

This study was conducted to compare the reproduction ability of the wild type boar and recombinant human erythropoietin (hEPO) transgenic boar semen. Ejaculated boar semen was analyzed by flow cytometry, Elisa and IVF methods. In experiment 1, flow cytometric analysis showed that the live sperm ratio of transgenic boar sperm significantly lower (P<0.05) than that of wild type boar after incubation at 20, 22, 24 and 26 hr. In experiment 2, the presence and levels of various cytokines (IL-6, IL-10 and $TNF-{\alpha}$) to related animal reproduction in the seminal and blood plasma were examined using specific enzyme immunoassay. There was no significant difference between both groups. In experiment 3, the fertilizing capacity and developmental ability of both boar sperm were compared. The transgenic boar sperm had a significantly low capacity of penetration, sperm-zona binding, embryo development, and blastocyst formation compared to wild type sperm (P<0.05). These results suggest that transgenic boar sperm harboring hEPO gene has low sperm viability than wild type boar, and it is a reason to decrease of fertility and litter size.

• 공업화학
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• 제16권4호
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• pp.563-569
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• 2005

발전소에서 운영하고 있는 해수전해장치의 전극에 부착물이 다량으로 부착하여 성능이 저하되고 전극 손상사고가 발생하고 있어 전극 부착물을 억제할 수 있는 방안을 연구하였다. 현재 사용하고 있는 grating type의 양극을 plate type으로 변경하고 양극판 수를 9매에서 8매로 줄이는 한편, 전극 간격을 2.4 mm에서 3.0 mm로 늘리고, 극간 간격을 유지하기 위한 스페이서를 27개에서 10개로 줄인 전해조를 개발하였다. 발전소 현장에 개발 전해조를 설치하여 성능을 시험한 결과 기존의 제품에 비하여 전류효율은 15~20% 높았고, 전극 부착물은 36~60% 감소하였으며, 전력소비율은 20% 정도 낮은 것으로 나타났다.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 하계학술발표대회 논문집
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• pp.1353-1357
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• 2008

A sea water source cascade heat pump was designed and tested in this study. The system was designed to perform a single stage operation in summer, as well as a cascade operation in winter to ensure the high temperature lift. A steady-state simulation model was developed to analyze and optimize its performance. The simulation results show that the R717 exhibits best performance among combinations considered in this study. A R410A also exhibits the highest performance among HFCs with the smallest compressor displacement. A 15-RT R410A-R134a pilot system was installed in the 5-story commercial building at Samcheok City by the East Sea. A scroll type R410A compressor, a reciprocating type R134a compressor, plate type condenser/ evaporator/ cascade heat exchanger and two electronic expansion valves were used to build a pilot. A titanium plate type heat exchanger is also used for the heat exchanging with a sea water. The heat source/sink water is supplied from the well below the seashore in the depth of 5 m. In the initial test of the system, supply water temperature was rising up to $67^{\circ}C$ using a sea water heat source of $9^{\circ}C$, while an ambient temperature was $4.5^{\circ}C$.

• Current Photovoltaic Research
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• 제1권1호
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• pp.17-26
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• 2013

In contrast to conventional crystalline cells, back-contact solar cells feature high efficiencies, simpler module assembly, and better aesthetics. The highest commercialized cell and module efficiency was recorded by n-type back-contact solar cells. However, the mainstream PV industry uses a p-type substrate instead of n-type due to the high costs and complexity of the manufacturing processes in the case of the latter. P-type back-contact solar cells such as metal wrap-through and emitter wrap-through, which are inexpensive and compatible with the current PV industry, have consequently been developed. In this paper the characteristics of EWT (emitter wrap-through) solar cells and their status and prospects for development are discussed.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 추계학술대회 논문집 전기기기 및 에너지변환시스템부문
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• pp.155-157
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• 2003

In this paper, CPM(controlled-permanent magnet)-type magnetic levitation system design is presented. The target plant to be controlled consists of eight magnets with permanent magnet and electromagnet. The design procedure is also described and the result of this work is shown.

• 한국약용작물학회지
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• 제22권5호
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• pp.363-368
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• 2014

This study was conducted to find out the optimum composition of nursery soil for raising seedling of ginseng (Panax ginseng C. A. Meyer). Total 9 kinds of raw materials were used such as peat-moss, perlite, leaf mould, rice bran, gull's guano, castor-oil plant bark, palm bark, cow manure and chicken manure for optimum composition of nursery soil in ginseng. Occurrence of damping-off in ginseng was lowered about 50% in nursery soil type 1, 2 and 4 than in other types nursery soil in June, and occurrence rate of rusty root also lowest in nursery soil type 1. As the salinity of nursery soil increased, so did the occurrence of physiological disorder in ginseng seedling. The cause of salinity increasing in nursery soil has closely relation to $NO_3-N$, $P_2O_5$ and $Na^+$ content. Plant height, root length, diameter and weight were longer and heavier in nursery soil type 1 (mixing ratio of peat-moss, perlite and leaf mould was 50 : 20 : 30 based in volume) than in other types of nursery soil. So nursery soil type 1 was selected for raising seedling of ginseng. pH and electric conductivity (EC) of selected nursery soil type 1 was 5.55 and 0.13 dS/m. Contents of $NO_3-N$ and $P_2O_5$ were 21.0 and 40.0 mg/L, and $K^+$ 0.36, $Ca^{2+}$ 3.38, $Mg^{2+}$ 2.01 and $Na^+$ $0.09cmol^+/L$, respectively.

• 문화기술의 융합
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• 제10권3호
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• pp.349-358
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• 2024

본 연구는 2010년부터 2023년까지 담화를 주제로 연구한 연구들을 중심으로 담화 연구에 대한 언어병리학의 전반적인 흐름 살펴보고자 문헌 분석을 실시하였다. 논문 25편을 선정하여 연구의 현황, 연구 대상(연령 및 대상자 유형), 연구 방법(유형 및 과제) 측면에서 분석하였다. 그 결과 첫째, 담화 연구의 연도별 현황을 살펴보면 2015년을 기점으로 2010년 ~ 2014년에 비해 증가하고 있음을 확인할 수 있었다. 둘째, 연구 대상자는 대상자의 연령과 실험연구의 실험집단 및 통제집단의 유형을 살펴보았다. 먼저 대상자의 연령을 분석해 보면, 학령기(12편, 48.00%) 대상으로의 연구가 활발히 진행되었다. 연구대상자 유형 분석 중 실험집단 대상자 유형 분석을 살펴보면 Normal 집단의 연구가 4편(19.04%)으로 가장 많았고, 통제집단 대상자 유형 또한 Normal을 통제집단으로 설정하고 진행한 연구가 13편(61.90%)으로 가장 많았다. 셋째, 연구 방법 분석에서 연구 유형의 경우 실험연구가 21편(84.00%)으로 매우 편중되어 있음을 알 수 있었다. 시간 관점의 연구 유형은 횡단연구가 21편(84.00%)으로 비중이 높게 나타났으며 담화능력을 평가하기 위하여 비중 높게 사용된 연구 과제는 담화 산출로 총12편(48.00%)이었다. 본 연구는 언어발달 및 언어장애와 관련 있는 담화 관련 연구를 종합적으로 살펴보고 최근의 동향에 대한 경향성과 함께 담화 관련 연구가 나아가야 할 방향을 도모해 보고자 하였다. 본 연구는 국내 논문으로 제한하여 분석하였다. 후속 연구에서는 담화와 관련된 국외 연구까지 포함하여 연구의 흐름을 파악하고 논의가 이루어질 것을 바란다.