• Title/Summary/Keyword: Research laboratory

Search Result 16,299, Processing Time 0.043 seconds

Effect of Acanthopanax koreanum on D-galactosamine and lipopolysaccharide-induced fulminant hepatitis

  • Park, Eun-Jeon;Nan, Ji-Xing;Zhao, Yu-Zhe;Lee, Sung-Hee;Kim, Young-Ho;Nam, Jeong-Bum;Lee, Jung-Joon;Sohn, Dong-Hwan
    • Proceedings of the PSK Conference
    • /
    • 2003.04a
    • /
    • pp.297.2-297.2
    • /
    • 2003
  • The roots and rhizome of Acanthopanax koreanum are used as folk medicine to ameliorate hepatitis in Korea. The ability of A. koreanum to protect mice from fulminant hepatitis induced in mice by D-galactosamine and lipopolysaccharide was evaluated. Preparations of A. koreanum used were an ethanol extract, and the ethanol-soluble and ethanol-insoluble components of the water extract. (omitted)

  • PDF

Protective Effects of Acanthoic acid on Tertiary-Butyl Hydroperoxide or Carbon tetrachloride-Induced Liver Injury

  • Park, Eun-Jeon;Nan, Ji-Xing;Zhao, Yu-Zhe;Lee, Sung-Hee;Kim, Young-Ho;Nam, Jeong-Bum;Lee, Jung-Joon;Sohn, Dong-Hwan
    • Proceedings of the PSK Conference
    • /
    • 2003.04a
    • /
    • pp.298.1-298.1
    • /
    • 2003
  • The aim of this study was to investigate the protective effect of acanthoic acid on liver injury induced by either tertiary-butyl hydroperoxide (tBH) or carbon tetrachloride in vitro and in vivo. Acanthoic acid, (-)-pimara-9(11),15-diene-19-oic acid, is a diterpene isolated from the root bark of Acanthopanax koreanum. In in vitro study, the cellular leakage of lactate dehydrogenase (LDH) with 1.5 mM tBH for 1 j, were significantly inhibited by treatment with acanthoic acid(25 and 5mg/mL). (omitted)

  • PDF

Synthesis of Methyl-substituted Bicyclic Carbanucleoside Analogs as Potential Antiherpetic Agents

  • Kim, Kyung-Ran;Park, Ah-Young;Lee, Hyung-Rock;Kang, Jin-Ah;Kim, Won-Hee;Chun, Pu-Soon;Bae, Jang-Ho;Jeong, Lak-Shin;Moon, Hyung-Ryong
    • Bulletin of the Korean Chemical Society
    • /
    • v.29 no.10
    • /
    • pp.1977-1982
    • /
    • 2008
  • Novel bicyclo[3.1.0]hexanyl purine nucleoside analogues were synthesized as potential antiherpetic agents via a bicyclo[3.1.0]hexanol (${\pm}$)-8, which was prepared using a highly efficient carbenoid cycloaddition reaction. A highly diastereoselective reduction of ketone and a Mitsunobu reaction for the condensation of glycosyl donor (${\pm}$)-12 with 6-chloropurine were employed.

First ClustalX-MPI for Ultra-fast Protein and Gene Discovery

  • Kim, Tae-Ho;Han, Jin;Youm, Jae-Boum;Kim, Na-Ri;Park, Won-Sun;Kang, Sung-Hyun;Cuong, Dang-Van;Kim, Hyoung-Kyu;Khoa, Tran Min;Thu, Vu Thi;Kim, Hyun-Ju;Moon, Hye-Jin;Lee, Hyun-Suk;Kim, Eui-Yong;Joo, Hyun
    • 한국생물공학회:학술대회논문집
    • /
    • 2005.10a
    • /
    • pp.296-296
    • /
    • 2005
  • PDF

MiDB: mitochondrial proteomics database in human heart

  • Kim, Tea-Ho;Joo, Hyun;Youm, Jae-Boum;Kim, Na-Ri;Park, Won-Sun;Kang, Sung-Hyun;Cuong, Dang-Van;Kim, Hyoung-Kyu;Khoa, Tran-Min;Thu, Vu-Thi;Kim, Hyun-Ju;Moon, Hye-Jin;Lee, Hyun-Suk;Kim, Eui-Yong;Han, Jin
    • 한국생물공학회:학술대회논문집
    • /
    • 2005.10a
    • /
    • pp.884-884
    • /
    • 2005
  • PDF