• Genomics & Informatics
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• v.2 no.1
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• pp.7-18
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• 2004

Integrated genomics refers to the use of large-scale, systematically collected data from various sources to address biological and biomedical problems. A critical ingredient to a successful research program in integrated genomics is the establishment of an effective computational infrastructure. In this review, we suggest that the computational infrastructure challenges include developing tools for heterogeneous data organization and access, innovating techniques for combining the results of different analyses, and establishing a theoretical framework for integrating biological and quantitative models. For each of the three areas - data integration, analyses integration, and model integration - we review some of the current progress and suggest new topics of research. We argue that the primary computational challenges lie in developing sound theoretical foundations for understanding the genome rather than simply the development of algorithms and programs.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.1
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• pp.24-45
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• 2012

In this paper, we present a survey of security and privacy preserving issues in M2M communications in Cyber-Physical Systems. First, we discuss the security challenges in M2M communications in wireless networks of Cyber-Physical Systems and outline the constraints, attack issues, and a set of challenges that need to be addressed for building secure Cyber-Physical Systems. Then, a secure architecture suitable for Cyber-Physical Systems is proposed to cope with these security issues. Eventually, the corresponding countermeasures to the security issues are discussed from four aspects: access control, intrusion detection, authentication and privacy preserving, respectively. Along the way we highlight the advantages and disadvantages of various existing security schemes and further compare and evaluate these schemes from each of these four aspects. We also point out the open research issues in each subarea and conclude with possible future research directions on security in Cyber-Physical Systems. It is believed that once these challenges are surmounted, applications with intrinsic security considerations will become immediately realizable.

• International Journal of Computer Science & Network Security
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• v.21 no.12
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• pp.123-130
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• 2021

Cybersecurity has been vital for decades and will remain vital with upcoming ages with new technological developments. Every new day brings advancement in technology, which leads to new horizons, and at the same time, it brings new security challenges. Numerous researchers around the globe are continuously striving hard to provide better solutions for the daily basis of new arising security issues. However, the challenges are always there. These challenges become new norms during the current Covid pandemic, where most industries, small industrial enterprises, education, finance, public sectors, etc. were under several attacks and threats globally. The hacker has more opportunities during the pandemic period by shifting most of the operations live. This research enlightened the several cybersecurity attacks and threats during this pandemic time globally. It provided the best possible recommendations to avoid them using the cyber awareness and with appropriately linked training. This research can provide a guideline to the above stated sector by identifying the related attacks.

• Journal of Information Processing Systems
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• v.15 no.3
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• pp.457-463
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• 2019

The blockchain and crypto currency has become one of the most essential components of a communication network in the recent years. Through communication networking, we browse the internet, make VoIP phone calls, have video conferences and check e-mails via computers. A lot of researches are being conducting to address the blockchain and crypto currency challenges in communication networking and provide corresponding solutions. In this paper, a diverse kind of novel research works in terms of mechanisms, techniques, architectures, and frameworks have been proposed to provide possible solutions against the existing challenges in the communication networking. Such novel research works involve thermal load capacity techniques, intelligent sensing mechanism, secure cloud computing system communication algorithm for wearable healthcare systems, sentiment analysis, optimized resources.

• Journal of the Korean Chemical Society
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• v.67 no.3
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• pp.165-174
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• 2023

The development of all-solid-state batteries (ASSBs) has been gaining attention in recent years due to their potential to offer higher energy densities, improved safety, and longer cycle life compared to conventional lithium-ion batteries. However, several challenges must be addressed to achieve the practical application of ASSBs, such as the development of high-performance solid-state electrolytes, stable electrode-electrolyte interfaces, and cost-effective manufacturing processes. In this review paper, we present an overview of the current state of ASSB research, including recent progress in solid-state electrolyte and cathode/anode materials, and cell architecture. We also summarize the recent advancements and highlight the remaining challenges in ASSB research, with an outlook on the future of this promising technology.

• The Korean Journal of Physiology and Pharmacology
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• v.28 no.5
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• pp.393-401
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• 2024

Large language models (LLMs) are rapidly transforming medical writing and publishing. This review article focuses on experimental evidence to provide a comprehensive overview of the current applications, challenges, and future implications of LLMs in various stages of academic research and publishing process. Global surveys reveal a high prevalence of LLM usage in scientific writing, with both potential benefits and challenges associated with its adoption. LLMs have been successfully applied in literature search, research design, writing assistance, quality assessment, citation generation, and data analysis. LLMs have also been used in peer review and publication processes, including manuscript screening, generating review comments, and identifying potential biases. To ensure the integrity and quality of scholarly work in the era of LLM-assisted research, responsible artificial intelligence (AI) use is crucial. Researchers should prioritize verifying the accuracy and reliability of AI-generated content, maintain transparency in the use of LLMs, and develop collaborative human-AI workflows. Reviewers should focus on higher-order reviewing skills and be aware of the potential use of LLMs in manuscripts. Editorial offices should develop clear policies and guidelines on AI use and foster open dialogue within the academic community. Future directions include addressing the limitations and biases of current LLMs, exploring innovative applications, and continuously updating policies and practices in response to technological advancements. Collaborative efforts among stakeholders are necessary to harness the transformative potential of LLMs while maintaining the integrity of medical writing and publishing.

• Asia Pacific Journal of Business Review
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• v.4 no.1
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• pp.61-77
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• 2019

This article explored the status of E-Government initiative in developing countries by taking the case of Ethiopia. The study had analyzed the practice, challenges and the future prospect of the E-Government initiative in the country. The paper had used both secondary and primary sources of data. In identifying the practice and future prospects of the E-Government imitative, related works in the area were reviewed and appraised. In ascertaining the major challenges, structured and semi-structured interviews were carried out with selected stakeholders from the government office and the private sector. The result of the study had shown that the country had registered a promising progress in E-Government index in the past four years ranking at 157th in the year 2014, which was standing at 172nd in the year 2012. Above all, high- level political commitment and the design of specific actions plans that are linked to the national sustainable development priorities were the key success factors. Nevertheless, there are still enormous challenges that have to be tackled for citizens to drive the benefits arising from the implementation of E-Government initiative. The study had identified limited cross-sectoral connectivity, lack of intra-organizational connectivity, low human resource capacity, language barrier, lack of awareness and absence of appropriate legal and regulatory framework as major challenges. Finally, the study forwarded constructive suggestion that can be adopted in the way forward of the E-Government initiative.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.476-483
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• 2022

The novel coronavirus pandemic has had a significant impact on society and everyday life. The pandemic imposed a global shutdown leading to many challenges such as the suspension of academic programs at universities. The result of this suspension contributed to the rapid overnight migration of educational activities from traditional face-to-face learning to a virtual environment which until then was unfamiliar to both instructors and students. This study identified the experiences faced by built environment higher education instructors in KwaZulu-Natal, South Africa during this sudden switch to online teaching and learning. This pilot study employed a quantitative research approach to survey instructor experiences on online teaching and learning during a global pandemic. The data was computed and analyzed using IBM Statistical Package for Social Sciences (SPSS) version 27. Descriptive statistics were used to analyze the data collected. The study sample comprised of 20 higher education instructors in the region of the KwaZulu Natal province in South Africa. Findings from the study revealed that instructors faced adaptive challenges with rapidly having to redesign and remodel the mode of academic course delivery and assessments to suit an online platform. Additionally, instructors observed that students faced technological challenges such as connectivity and navigating the online learning management system platforms. The challenges identified by instructors and students can be effectively transformed to opportunities for future learning under the 'new normal'.

• International Journal of Computer Science & Network Security
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• v.24 no.8
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• pp.145-152
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• 2024

Agile project management is an ongoing method to project completion that actually took place all across length of the project's life cycle. Because loop allows you to adapt as you go rather than maintaining a linear route, iterative methods are mainly applied in software development to ensure velocity and agility. Many pitfalls abound in agile software development adaptations that organizations fail to sidestep. New competitive challenges, fluctuating market dynamics, technological disruption, and the ever-changing demands of empowered customers confront organizations around the world. Organizations are all under tremendous pressure to adapt to change and deliver good products and services to customers more swiftly. Research measured at the challenges that could be encountered and offered advice for how agile development might flourish as it becomes a component of a company's family. Our paper gives a comprehensive review of the most significant obstacles that companies encounter while adopting agile techniques. Adaptability. The agile approach encompasses a variety of techniques, which each have different usage in various sectors. Because certain other standards existing today clash with agile methodology, the adaptation of any of the agile techniques in work environments posed a problem. In this paper, we will cover some of the challenges that firms face in adopting the agile software development life cycle.

• Journal of Information Management
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• v.41 no.4
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• pp.93-118
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• 2010

This study was aimed to establish a workable strategies to operate KESLI consortium reliably. To encourage the research purposes, it was mainly investigated international literature on current challenges for the e-journals consortium in comparison with the domestic implications. Major issues and challenges are divided to six items by scholarly communication changes and e-journals percentage increase, a big deal for a contract -based consortium pricing model in vogue, a consortium of the price hikes and making budget difficulties, use the standard statistics by the results of the use, archiving and archive security uncertainty, and contracts public availability of such external conditions. As a result, the international challenges of E-journals consortium was similar to KESLI, but the depth of information and research on domestic was weaker than the international research. To see more research and a rational perception based on scientific evidence and alternatives that enable KESLI working in the field was needed to be.