• Title/Summary/Keyword: Research and Development Department

Search Result 20,289, Processing Time 0.062 seconds

Spillovers of Education and Job Training in Bringing Sustainable Economic Development in Pakistan: The Role of Research and Development Revisited

  • AMIN, Sara;LIAQAT, Malka;SAFDAR, Noreen;IQBAL, Sidra
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.9 no.5
    • /
    • pp.11-18
    • /
    • 2022
  • Current research intended to measure the spillovers of education and on-the-job training to enhance sustainable economic development. Consideration of research and development expenditures for on-the-job training expands the impact of education and, thus, may provide spillovers for Pakistan's economic growth. The primary focus of this research is to look at the combined impact of education and research and development spending as value-added variables for sustainable growth. The econometric study uses data from a variety of sources, including the Pakistan Bureau of Statistics, the Pakistan Economic Survey, and world development indices. The secondary annual time series data from 1976 to 2019 are analyzed. To adequately estimate the empirical model, ARDL has been used while the presence of the unit root has been tested using the ADF test. The findings show that education, research, and development all contribute to all-inclusive, sustainable economic growth. Labor and capital, among other traditional components, continue to be the backbone of the development process. Still, the spillover effect is much enhanced with the expansion in education and the on-job training in the form of research and development expenditures. Consequently, the introduction of research and development in education will lead to a sustainable and inclusive economy.

Characterization of Placental Proteins in Bovine Somatic Cell Clone Fetuses

  • Woo, Jei-Hyun;Ko, Yeoung-Gyu;Kim, Bong-Ki;Kim, Jong-Mu;Lee, Youn-Su;Kim, Nam-Yun;Im, Gi-Sun;Yang, Boung-Chul;Seong, Hwan-Hoo;Jung, Jin-Kwan;Kwun, Moo-Sik;Chung, Hak-Jae
    • Reproductive and Developmental Biology
    • /
    • v.29 no.2
    • /
    • pp.83-91
    • /
    • 2005
  • Somatic cell nuclear transfer in cattle has limited efficiency in terms of production of live offspring due to high incidence of fetal failure after embryo transfer to recipients. Such low efficiency of cloning could possibly arise from abnormal and poorly developed placenta. In the present study the placental proteome in late pregnancy established from in vitro fertilization (IVF) and nuclear transfer (NT) was analysed. Proteome alternation was tested using two-dimensional polyacrylamide gel electrophoresis (2-DE) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI- TOF). Comparing placenta from NT embryos to those from IVF counterparts, significant changes in expression level were found in 18 proteins. Of these proteins 12 were not expressed in NT placenta but expressed in IVF counterpart, whereas the expression of the other 6 proteins was limited only in NT placenta. Among these proteins, cytokeratin 8 and vimentin are considered to be involved in regulation of post-implantation development. In particular, cytokeratin 8 and vimentin may be used as makers for placental development during pregnancy because their expression levels changed considerably in NT placental tissue compared with its IVF counterpart. Data from 2-DE suggest that protein expression was disorientated in late pregnancy from NT, but this distortion was eliminated with progression of pregnancy. These findings demonstrate abnormal placental development during late pregnancy from NT and suggest that alterations of specific placental protein expression may be involved in abnormal function of placenta.

Development of Dementia Treatment VR System (치매 치료 VR 시스템 개발)

  • Lee, Ki-Suk;Kim, Sang-Won;Kim, Young-Wan;Kim, Min-Young;Choi, Jin-Sung
    • Proceedings of the Korea Information Processing Society Conference
    • /
    • 2002.11a
    • /
    • pp.835-838
    • /
    • 2002
  • 사회고령화 추세에 따라 노인들이 증가하고 있으며 자연적으로 발생률이 높아지고 있는 치매에 대한 사회적 문제가 대두되고 있다. 본 논문에서는 경증 치매나 치매에 걸릴 확률이 높은 사람들에게 치매 치료의 효과를 주는 VR기반의 의료시스템을 개발하여 치매 치료에 대한 새로운 방법을 제시하려고 한다. 제시하는 치료 요법은 사용자에게 일상생활과 유사하게 VR 환경을 제공하고 일상적인 문제에 대처하여 올바르게 수행하도록 하는 방법을 가진다. 개발되어진 다양한 시나리오의 반복 수행을 통하여 치매의 치료는 수행되게 된다. 본 시스템의 효과를 판단하기 위해 실험군과 대조군 각 15명을 통하여 임상실험을 수행하였으며 그 결과를 보였다.

  • PDF

The role of autophagy in cell proliferation and differentiation during tooth development

  • Ji-Yeon Jung;Shintae Kim;Yeon-Woo Jeong;Won-Jae Kim
    • International Journal of Oral Biology
    • /
    • v.48 no.4
    • /
    • pp.33-44
    • /
    • 2023
  • In this review, the regulatory mechanisms of autophagy were described, and its interaction with apoptosis was identified. The role of autophagy in embryogenesis, tooth development, and cell differentiation were also investigated. Autophagy is regulated by various autophagy-related genes and those related to stress response. Highly active autophagy occurrences have been reported during cell differentiation before implantation after fertilization. Autophagy is involved in energy generation and supplies nutrients during early birth, essential to compensate for their deficient supply from the placenta. The contribution of autophagy during tooth development, such as the shape of the crown and root formation, ivory, and homeostasis in cells, was also observed. Genes control autophagy, and studying the role of autophagy in cell differentiation and development was useful for understanding human aging, illness, and health. In the future, the role of specific mechanisms in the development and differentiation of autophagy may increase the understanding of the pathological mechanisms of disease and development processes and is expected to reduce the treatment of various diseases by modulating the autophagic phenomenon.

Complete genome sequence of functional probiotic candidate Lactobacillus amylovorus CACC736

  • Soyeon Park;Jung-Ae Kim;Hyun-Jun Jang;Dae-Hyuk Kim;Yangseon Kim
    • Journal of Animal Science and Technology
    • /
    • v.65 no.2
    • /
    • pp.473-477
    • /
    • 2023
  • Lactobacillus amylovorus CACC736 was originated from swine feces in Korea. The complete genome sequences of the strain contained one circular chromosome (2,057,809 base pair [bp]) with 38.2% guanine-cytosine (GC) content and two circular plasmids, namely, pCACC736-1 and pCACC736-2. The predicted protein-coding genes, which are encoding the clustered regularly interspaced short palindromic repeats (CRISPR)-associated proteins, biosynthesis of bacteriocin (helveticin J), and the related proteins of the bile, acid tolerance. Notably, the genes related to vitamin B-group biosynthesis (riboflavin and cobalamin) were also found in L. amylovorus CACC736. Collectively, the complete genome sequence of the L. amylovorus CACC736 will aid in the development of functional probiotics in the animal industry.

HPLC-based metabolic profiling and quality control of leaves of different Panax species

  • Yang, Seung-Ok;Lee, Sang Won;Kim, Young Ock;Sohn, Sang-Hyun;Kim, Young Chang;Hyun, Dong Yoon;Hong, Yoon Pyo;Shin, Yu Su
    • Journal of Ginseng Research
    • /
    • v.37 no.2
    • /
    • pp.248-253
    • /
    • 2013
  • Leaves from Panax ginseng Meyer (Korean origin and Chinese origin of Korean ginseng) and P. quinquefolius (American ginseng) were harvested in Haenam province, Korea, and were analyzed to investigate patterns in major metabolites using HPLC-based metabolic profiling. Partial least squares discriminant analysis (PLS-DA) was used to analyze the the HPLC chromatogram data. There was a clear separation between Panax species and/or origins from different countries in the PLS-DA score plots. The ginsenoside compounds of Rg1, Re, Rg2, Rb2, Rb3, and Rd in Korean leaves were higher than in Chinese and American ginseng leaves, and the Rb1 level in P. quinquefolius leaves was higher than in P. ginseng (Korean origin or Chinese origin). HPLC chromatogram data coupled with multivariate statistical analysis can be used to profile the metabolite content and undertake quality control of Panax products.