• Title/Summary/Keyword: Research and Development Department

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Heterologous Microarray Hybridization Used for Differential Gene Expression Profiling in Benzo[a]pyrene-exposed Marine Medaka

  • Woo, Seon-Ock;Won, Hyo-Kyoung;Jeon, Hye-Young;Kim, Bo-Ra;Lee, Taek-Kyun;Park, Hong-Seog;Yum, Seung-Shic
    • Molecular & Cellular Toxicology
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    • v.5 no.4
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    • pp.283-290
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    • 2009

  • Differential gene expression profiling was performed in the hepatic tissue of marine medaka fish (Oryzias javanicus) after exposure to benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon (PAH), by heterologous hybridization using a medaka cDNA microarray. Thirty-eight differentially expressed candidate genes, of which 23 were induced and 15 repressed (P<0.01), were identified and found to be associated with cell cycle, development, endocrine/reproduction, immune, metabolism, nucleic acid/protein binding, signal transduction, or non-categorized. The presumptive physiological changes induced by BaP exposure were identified after considering the biological function of each gene candidate. The results obtained in this study will allow future studies to assess the molecular mechanisms of BaP toxicity and the development of a systems biology approach to the stress biology of organic chemicals.

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Breeding and Production Research Direction for Soybean Self-Sufficiency Improvement in Korea

  • Jee-Yeon Ko;Beom-Kyu Kang;Jeong-Hyun Seo;Jun-Hoi Kim;Su-Vin Heo;Man-Soo Choi;Jae-Bok Hwang ;Choon-Song Kim;Myeong-Gyu Oh
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.23-23
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    • 2022

  • Recently, soybean production and market price are unstable, even if demand of soybean is maintained. Diverse conditions such as climate change, a decrease in rural population, and consuming affect food industry. In this situation, food security is soaring as important key-word again, and MAFRA is promoting policies for improving soybean self-sufficiency with the goal of 40% until 2030. The point of policy is to extend a production and stabilize a demand for soybean with supporting large-scale soybean paddy-field complex. According to the background, soybean breeding and production research in NICS are proceeded with three parts. First, production improvement with soybean cultivation land enlargement and high-yield cultivar development. Various growth period soybean cultivars for double cropping, irrigation management technologies in paddy field, and hyper-yield and specific-region adaptable cultivar development. Second, reduction of production expense with mechanized cultivation and digital-based field management technologies. Third, consumer-friendly and high quality soybeans with high protein cultivar for alternative protein usage and high food process-ability for soy milk, tofu, soybean sprouts, and grain usage. Each part need to be combined and advanced to improve soybean industry and soybean self-sufficiency.

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