Journal of Physiology & Pathology in Korean Medicine
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제34권5호
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pp.215-221
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2020
Adulterated herbal medicine is intentionally added with undeclared improper or inferior ingredients which should not be in herbal medicine. The contamination with potentially hazardous substances such as heavy metal, pesticides, fungus, and microorganism sometimes can be regarded as one of adulteration in a broad sense. The problem of adulteration is that adulterated herbal medicine shows poor quality and/or can cause adverse events. Therefore, it is important to control adulteration issues for quality assurance and qualitative improvement of herbal medicines. This study aims to summarize and make a reference how to control adulterated herbal medicine. In this process, this study is to investigate studies about adulterated herbal medicine via searching Korean and foreign electronic databases such as PubMed, NDSL and OASIS. Finally eighteen papers were included to this study and analyzed according to the type of study, the category and efficacy of adulterants, the type of analysis methodologies and possible adverse events of adulterants. Phosphodiesterase type 5 (PDE-5) inhibitors for male sexual enhancement and anorexic, laxative, diuretic agents for weight loss and treating obesity has been used frequently as adulterants. The range of adverse event caused by adulterated herbal medicine were very wide from mild symptoms such as diarrhea, constipation, dizziness and blurred vision to very severe symptoms such as heart failure, hypoglycemia and renal impairment. This study showed the recent trend on the research of adulterated herbal medicine and this will be the ground to develop more detailed systems to control adulterated herbal medicine.
This study was initiated out of necessity to inquire into the trend of costume regulation between the mid-15th century and mid-17th century, and what influence the change of dress and its ornaments had on the people at the time. As for the resources this study was based on, the True Record of Joseon Dynasty, which was the historical record of official compilation, was used as basic material, and the excavated relics at the time were referred to. The forbidden dress and ornaments mentioned in the records from the time of King Seonjong to the time of King Hyeonjong were classified into textiles, clothes, ornaments and dresses, according to the objects. It was designed to identify the laws and ordinances or regulations enacted by the state and the contents of discussions, which were caused by the extensive consumption of silk gauze and fabrics and the luxury in dress and ornaments, and the phenomenon induced by the consumption desire of the social class with economic power, and to help understand the cause. So to speak, the law and ordinance or regulations were established to solve the social problems caused by the failure in controlling dress and ornaments wearing based on social position, during the process in which the king and court officials were making effort to intensify their political power in each regime.
KSCE Journal of Civil and Environmental Engineering Research
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제29권6C호
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pp.295-301
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2009
In general the stability of soil nail-slope system, the shear resistance is neglected because the tensile resistance of nail acts mainly for slope stabilization. This is because that deformed steel is generally used for nail and it does ductile behavior. In other side when the steel pipe with high rigidity is used for nail, the shear resistance at failure surface work more than deformed steel. In order to analyze effects of shear resistance at the soil nail-slope system with high steel piped nail, a series of numerical analyses were performed. Also numerical analyses at 3 conditions - 5 nailed, 7 nailed, 9 nailed at the same slope were perfomed for investigating the trend of shear resistance effect. From these 3D numerical analyses, it was found that the maximum shear resistances at each nails were larger in case of steel piped nail and because of this, the factor of safety at the condition of the steel piped nail appears larger than that of deformed steel nail.
Reliability test is focusing to detect the unexpected reliability failure and solve them for the high quality of products. The test data should be used to assess and project the current level of interesting product reliability and so it is very important to have the accurately assessing methodology with test data. There are two type of trend for test data as constant and changing one during testing and this paper shows the difference in the assessing results of these two cases. There is less information how to define the existence of reliability growth rate changing and calculate the parameters of the reliability growth models to make an accurate assessment with such condition, so i established the process and mathematical model to calculate the parameters at such condition to make reliability growth curve with high Goodness of Fit. I validated the new method with the data made from Monte Carlo Simulation and case from Demko (1993). Even the assessed result with the new methodology may be different with the case by case because of very diversity in test condition and testing product quality, but the process and method founded in this research can be applied to any case using Duane and AMSAA model for their test data assessment. I also present the evaluation method to see the effectiveness with new one which is a conventional knowledge and not popular to use, so it is possible to compare the results with the newly presented and conventional method for better business decision.
KSCE Journal of Civil and Environmental Engineering Research
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제26권5C호
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pp.313-322
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2006
Liquefaction of soil foundation is one of the major seismic damage types for infrastructures. In this paper, deterministic and probabilistic approaches for the evaluation of liquefaction potential are briefly summarized and the risk assessment method is newly proposed using seismic fragility and seismic hazard analyses. Currently the deterministic approach is widely used to evaluate the liquefaction potential in Korea. However, it is very difficult to handle a certain degree of uncertainties in the soil properties such as elastic modulus and resistant capacity by deterministic approach, and the probabilistic approaches are known as more promising. Two types of probabilistic approaches are introduced including (1) the reliability analysis (to obtain probability of failure) for a given design earthquake and (2) the seismic risk analysis of liquefaction for a specific soil for a given service life. The results from different methods show a similar trend, and the liquefaction potential can be more quantitatively evaluated using the new risk analysis method.
Reliability growth rate (or reliability growth curve slope) have the two cases of trend as a constant or changing one during the reliability growth testing. The changing case is very common situation. The reasons of reliability growth rate changing are that the failures to follow the NHPP (None-Homogeneous Poisson Process), and the solutions implemented during test to break out other problems or not to take out all of the root cause permanently. If the changing were big, the "Goodness of Fit (GOF)" of reliability growth curve to test data would be very low and then reduce the accuracy of assessing result with test data. In this research, we are using Duane model and AMSAA model for assessing test data and projecting the reliability level of complex and repairable system as like construction equipment and vehicle. In case of no changing in reliability growth rate, it is reasonable for reliability engineer to implement the original Duane model (1964) and Crow-AMSAA model (1975) for the assessment and projection activity. However, in case of reliability growth rate changing, it is necessary to find the method to increase the "GOF" of reliability growth curves to test data. To increase GOF of reliability growth curves, it is necessary to find the proper parameter calculation method of interesting reliability growth models that are applicable to the situation of reliability growth rate changing. Since the Duane and AMSAA models have a characteristic to get more strong influence from the initial test (or failure) data than the latest one, the both models have a limitation to contain the latest test data information that is more important and better to assess test data in view of accuracy, especially when the reliability growth rate changing. The main objective of this research is to find the parameter calculation method to reflect the latest test data in the case of reliability growth rate changing. According to my experience in vehicle and construction equipment developments over 18 years, over the 90% in the total development cases are with such changing during the developing test. The objective of this research was to develop the newly assessing method and the process for GOF level increasing in case of reliability growth rate changing that would contribute to achieve more accurate assessing and projecting result. We also developed the new evaluation method for GOF that are applicable to the both models as Duane and AMSAA, so it is possible to compare it between models and check the effectiveness of new parameter calculation methods in any interesting situation. These research results can reduce the decision error for development process and business control with the accurately assessing and projecting result.
Journal of the Korean Institute of Traditional Landscape Architecture
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제33권4호
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pp.77-86
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2015
The Koreanology as well as a study of the classics should start from the correct understanding of certain words or concepts. Inaccurate or even misinterpreted explanation is bound to lead to failure. If you read a classic text, if the object does not come up to indicate clearly what the bar often. Bout, are seen refer to the translation or commentary, sometimes encounter cases of very serious misunderstanding. If a simple mistake or error, and if you recognize and fix it, but eopget a big problem, described by early to conclude identified by the fact that the amount of problem becomes serious. Besides, if the trend will spread to quote it, the situation is not out of control. One sample is "Nodongchwibyeong(老松翠屛)" in "Kyoungdojapji(京都雜誌)" "Poonsock(風俗)" "Jetaek(第宅). In some places, it is called "Booyeon(附椽), it has been described elsewhere as a kind of "chwibyeong(翠屛)". This short manuscript clarified by reviewing the old literature closely, it was "songcheom", "songboong(松棚), another expression of Bungga(棚架). More precisely, it was a nickname of Hanyang Yangban in the 18th and 19th century. However, the historical research is just not as having a meaning only one explanation for the particular word. Dare to be confident that these study are meaningful. In the extremely weak division in the understanding of the original text, the cases of applying blindly without a reflection occurs frequently. This short manuscript is to give warning to recent trends. Humanities and classical field researchers made very carefully, taking into account the impact of translation and annotations, and the other branch to accommodate the research of classical humanities disciplines should try to see this information must be verified meets the facts.
The main causes of the July 2013 OZ 214 accident were poorly performed approach and the failure to recognize the autothrottle in the HOLD position which the automated speed control was not provided. The pilots late decision for go-around was also a critical factor leading to the accident. The B777 POM restricts the use of FLCH mode beyond the FAF. This research utilized the QAR data of an airline's B777 fleet in the period of two years where 44 cases were found. In many cases, the FLCH mode was used for rapid descent from an higher than normal situation. In addition, in the base turn, continuous use of FLCH mode even when the path was below the glide path were observed. Airports with elevation above 500 ft MSL had a higher rate of occurrence. In this research, the proper descent planning and vertical path monitoring, and the adherence to the limitation set in the manuals and the stabilized approach criteria were re-emphasized as mitigation to reduce event occurences.
Shim, Jung Ok;Kim, Seung;Choe, Byung-Ho;Seo, Ji-Hyun;Yang, Hye Ran
Nutrition Research and Practice
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제14권3호
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pp.230-241
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2020
BACKGROUND/OBJECTIVES: Inadequate nutrition in infants and young children affects physical growth and neurocognitive development. Therefore, early nutritional intervention is important to promote catch-up growth in young children with faltering growth. The aim of this study was to evaluate the effect of nutritional supplementation with a pediatric concentrated and balanced nutritional supplement formula on promoting growth and improving nutritional status in children with nonorganic faltering growth. SUBJECTS/METHODS: Children aged 12-36 months whose body weight-for-age was < 5th percentile on the Korean Growth Charts were enrolled. Children born premature or having organic diseases were excluded. Children were instructed to consume 400 mL of formula per day in addition to their regular diet for 6 months. Pediatricians and dietitians educated the parents and examined the subjects every 2 months. Anthropometric parameters were measured at baseline and at 2, 4, and 6 months, and laboratory tests were done at baseline and 6 months. The good consumption group included children who consumed ≥ 60% of the recommended dose of formula. RESULTS: Total 82 children completed the 6-month intervention. At baseline, there were no significant differences in all variables between the good consumption and poor consumption groups. Weight and weight z-scores were significantly improved in the good consumption group compared to the poor consumption group at the end of the intervention (P = 0.009, respectively). The good consumption group showed a significant trend for gaining weight (P < 0.05) and weight z-score (P < 0.05) compared to the poor consumption group during 6 months of formula intake. The concentration of blood urea nitrogen was significantly increased in the good consumption group (P = 0.001). CONCLUSIONS: Nutritional supplementation with a concentrated and balanced pediatric nutritional formula along with dietary education might be an effective approach to promote catch-up growth in children with nonorganic faltering growth.
Purpose: The trend of highway traffic accidents shows a repeating pattern of increase and decrease, with the fatality rate being highest on highways among all road types. Therefore, there is a need to establish improvement measures that reflect the situation within the country. Method: We conducted accident severity analysis using Random Forest on data from accidents occurring on 10 specific routes with high accident rates among national highways from 2019 to 2021. Factors influencing accident severity were identified. Result: The analysis, conducted using the SHAP package to determine the top 10 variable importance, revealed that among highway traffic accidents, the variables with a significant impact on accident severity are the age of the perpetrator being between 20 and less than 39 years, the time period being daytime (06:00-18:00), occurrence on weekends (Sat-Sun), seasons being summer and winter, violation of traffic regulations (failure to comply with safe driving), road type being a tunnel, geometric structure having a high number of lanes and a high speed limit. We identified a total of 10 independent variables that showed a positive correlation with highway traffic accident severity. Conclusion: As accidents on highways occur due to the complex interaction of various factors, predicting accidents poses significant challenges. However, utilizing the results obtained from this study, there is a need for in-depth analysis of the factors influencing the severity of highway traffic accidents. Efforts should be made to establish efficient and rational response measures based on the findings of this research.
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