• Journal of Preventive Medicine and Public Health
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• v.44 no.3
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• pp.118-124
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• 2011

Objectives: Although cigarette smoking is known to be related to the exacerbation of asthma symptoms, several studies have indicated that the prevalence of cigarette smoking among asthmatic adolescents is similar to or even higher than that among non-asthmatic adolescents. The aim of this study was to evaluate the relationship between asthma and cigarette use behaviors and whether or not the presence of suicidal ideation modifies this relationship among Korean adolescents. Methods: We analyzed data from the 2008 Korea Youth Risk Behavior Web-based Survey, which included a nationally representative sample of middle and high school students. Multiple logistic regression models were used to calculate odd ratios and 95% confidence intervals of cigarette use behaviors among current asthmatics, former asthmatics, and nonasthmatics, after adjusting for gender, grade, school records, socioeconomic status, current alcohol use, and suicidal ideation. Results: Of 75 238 study participants, 3.5% were current asthmatics and 4.5% were former asthmatics. Compared with non-asthmatics, asthmatics were more likely to report current cigarette use, frequent and heavy cigarette use, and cigarette use before 13 years of age. There were statistically significant interactions between asthma and suicidal ideation in cigarette use behaviors. Conclusions: This study demonstrated that asthmatic adolescents are more likely than non-asthmatic adolescents to engage in cigarette use behaviors and the presence of suicidal ideation is an effect modifier of the relationship between asthma and cigarette use behaviors. Particular attention should be paid to the awareness of health risks of cigarette smoking and mental health problems among asthmatic adolescents.

• The Plant Pathology Journal
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• v.28 no.3
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• pp.299-305
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• 2012

Petunia hybrida is commonly used in landscapes and interiors for its attractive flower. Virus-like foliar symptoms, including a mosaic with dark green islands surrounding the veins and chlorosis on the leaf margins, were observed on a petunia plant from Icheon, Gyeonggido, Korea. Cucumber mosaic virus (CMV) was identified in the symptomatic petunia by serological testing for the presence of CMV coat protein (CP) with a direct antibody-sandwich-enzyme-linked immunosorbent assay. An agent was mechanically transmitted to indicator plant species including Chenopodium quinoa. Examination of the inoculated plant leaves by RT-PCR analysis and electron microscopy revealed the presence of specifically amplified CP products and spherical virions of approximately 28 nm in diameter, respectively, providing confirmation of a CMV infection. Analysis of CP sequences showed that CMV petunia isolate (CMVYJC) shared 82.5-100% amino acid sequence identity with CPs of representative CMV strains. Phylogenetic analysis of CPs supports that CMV-YJC is a member of CMV subgroup IA (CMV-IA) and has biological properties of CMV-IA on host species. To our knowledge, this is the first report of CMV from P. hybrida in Korea.

• Journal of Chest Surgery
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• v.21 no.3
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• pp.510-517
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• 1988

With the ligation of a patent ductus arteriosus by Gross in 1938, surgeons first entered the field of congenital heart disease, and treatment of the patent ductus is representative of the rapid advance made in thoracic surgery in the last 40 years. We have had clinical experiences about 36 cases of this in the department of Thoracic & Cardiovascular surgery, Pusan Paik Hospital, Inje medical college from March 1891 to June 1987. And the results were summarized as follows. 1. There were 11 males, 25 females. The age range of the patients were from 8 months to 36 years with the mean age of 7.9 years. 2. The chief complaints of the patients on admission were frequent URI[50%], dyspnea on exertion[29.8%], chest pain[11.1% k 1%], growth retardation[2%], cough[2.8%], anorexia[2.8%]. But there were 11 patients[30.6%] having no subjective symptoms. 3. In auscultation, the usual continuous machinery murmur was noticed in 30 patients[83.3%], only systolic murmur in 6[16.7%]. 4. In the preoperative chest P-A views, there were noticed cardiomegaly in 20 cases, enlarged pulmonary conus and / or pulmonary plethora in 22 patients[61.1%]. 5. In the preoperative EGG findings, there were noticed pattern of LVH in 8 patients[22.2`], RVH in 2[5.6%], BVH in 4[11.5%] and normal in 19[52.89o]. 6. The size of PDA[mean] was 9.5 mm[length] and 8.8 mm[width], the range of length was from 4 to 29 mm and the range of width was from 4 to 18 mm. 7. There were noticed 6 cases which were combined with other anomalies[VSD in 2 cases, Coarctation of aorta in 2, Mitral regurgitation in 1, and AP window in 1]. 8. On operation, simple ligation of the ductus was performed in 30 cases[83.3%], division and suture-ligation in 5[13.9%]. 9. Postoperative complications were noticed in 4 cases[pneumonia in one case, wound infection or disruption in 3], but there were no mortality.

• The Korean Journal of Cytopathology
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• v.16 no.1
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• pp.52-56
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• 2005

Fine-needle aspiration cytology (FNAC) has been used extensively in the diagnosis of metastatic malignancies. However, metastatic soft tissue sarcomas are often overlooked, primarily due to the low frequency with/ which they occur. Here, we report a rare case of metastatic rhabdomyosarcoma in both cervical lymph nodes, which was detected by FNAC. A 45-year-old woman presented with anosmia, postnasal drip, and sneezing, symptoms which had persisted for 1 month. The patient was found to have a tumorous lesion at the upper portion of the mid-turbinate, with multiple enlarged cervical lymph nodes, and this lesion was examined closely at our facility. FNA cytology smears obtained from both cervical lymph nodes revealed a high degree of cellularity, and displayed cohesive clusters with gland-like spaces, as well as single isolated cells with abundant karyorrhectic debris. The tumor cells exhibited round to oval nuclei containing fine chromatin, occasional small nucleoli, and scanty cytoplasm, or a total lack of cytoplasm. Some of the tumor cells were arranged in multinucleated forms and abundant dense eosinophilic cytoplasms, reminiscent of a rhabdomyoblast. The histological findings on the lymph nodes revealed an outstanding sinusoidal infiltration and a prominent alveolar growth pattern, interspersed with occasional typical rhabdomyoblasts. The immunohistochemical results [desmin (+), myoglobin (+), myogenin (+), pan CK (-), synaptophysin (-), neuron specific enolase (-)] supported a confirmative diagnosis of alveolar rhabdomyosarcoma. Alveolar rhabdomyosarcoma is a representative sarcoma, which typically manifests with nodal metastasis and carcinoma-like clustering. The cytopathologist should remain alert upon encountering unusual morphology, so that the possibility of this condition, although somewhat remote, should not be dismissed or overlooked.

• The Korean Journal of Pain
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• v.27 no.1
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• pp.54-62
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• 2014

Background: The recently known analgesic action mechanisms of nefopam (NFP) are similar to those of anticonvulsants and antidepressants in neuropathic pain treatment. It is difficult to prescribe high doses of oral neuropathic drugs without titration due to adverse effects. Unfortunately, there are few available intravenous analgesics for the immediate management of acute flare-ups of the chronic neuropathic pain. The aim of this study was to determine the additional analgesic effects for neuropathic pain of NFP and its adverse effects during the titration of oral medications for neuropathic pain among inpatients with postherpetic neuralgia (PHN). Methods: Eighty inpatients with PHN were randomly divided into either the NFP or normal saline (NS) groups. Each patient received a 3-day intravenous continuous infusion of either NFP with a consecutive dose reduction of 60, 40, and 20 mg/d, or NS simultaneously while dose titrations of oral medications for neuropathic pain gradually increased every 3 days. The efficacy of additional NFP was evaluated by using the neuropathic pain symptom inventory (NPSI) score for 12 days. Adverse effects were also recorded. Results: The median NPSI score was significantly lower in the NFP group from days 1 to 6 of hospitalization. The representative alleviating symptoms of pain after using NFP were both spontaneous and evoked neuropathic pain. Reported common adverse effects were nausea, dizziness, and somnolence, in order of frequency. Conclusions: An intravenous continuous infusion of NFP reduces spontaneous and evoked neuropathic pain with tolerable adverse effects during the titration of oral medications in inpatients with PHN.

• Korean Journal of Clinical Pharmacy
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• v.19 no.2
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• pp.153-158
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• 2009

Background: Patients with chronic myeloid leukemia(CML) have different health status according to their disease conditions such as chronic phase(CP), accelerated phase(AP), blast crisis(BC), stage with MCyR(Major Cytogenetic Response); therefore, every patient has different quality of life related to their disease condition. Objectives: To measure the quality of life, this study compared and analyzed the utility weight in patients with CML. This study also evaluated the utility weight in order to view comparisons between the quality of life in a patient with CML to a patient with diabetes, which is a representative chronic disease. Methods: The disease scenario described 5 symptoms of the CP, AP, BC of the CML, the CML which gets the MCyR and the diabetes. Utility weight was developed using the EQ-5D method. All statistical data were analyzed by STATA 10.0 Results: 57 nurses(95%) out of 60 answered the questionnaire. In CP, the utility weight was 0.7946. In AP, it was 0.5301. and in BC, it was -0.2793. Survey data indicate that the worse the condition of a disease, the lower the utility weight. In case of the CML which gets the MCyR, the result was 0.7731(95% CI : 0.7384 - 0.8079). The general diabetes which has no complicating disease, the utility weight was 0.7481(95% CI : 0.6983 - 0.7978). Based on the result, it is evident that those with MCyR are not significantly different from people with general diabetes (p=0.4096) in views of the quality of life.

• Korean Journal of Child Studies
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• v.38 no.2
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• pp.165-176
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• 2017

Objective: Delinquent peers are important predictors of adolescent delinquent behavior. Few studies have classified individuals into groups based on patterns of delinquent behavior among youth and their peers. This study identified latent groups based on adolescent-peer delinquency and examined psychosocial characteristics of each latent group. Methods: First, the study employed latent class analysis based on a nationally representative data of South Korean middle school students (N = 2,277). Both adolescent and peer delinquent behaviors comprised 13 items in the questionnaire that was self-reported by adolescents. Second, the study used multivariate regression models to analyze psychosocial symptoms of latent groups and conducted Wald tests to compare differences among latent groups. Results: Patterns of adolescent-peer delinquency were classified into six latent groups. "Mutual total delinquent group (1.2%)" showed high rates in most delinquent experiences. "Mutual status delinquent group (5.7%)" mainly experienced status delinquency, "Mutual violence delinquent group (5.3%)" showed high rates of violent delinquency. "Peer-only total high delinquent group (3.8%)" reported friends to have engaged in all types of delinquency and "Peer-only total medium delinquent group (11.8%)" reported peer involvement in multiple status and few violent delinquency. Finally, "low risk group (72.2%)" reported low rates of delinquency for themselves and their friends. Regression analysis showed that every "mutual" delinquent group presented significantly worse psychosocial problems than the "low risk group." Conclusion: Using person centered latent class analysis, this study classified six latent classes while considering both delinquent agents and various types of delinquency and investigated specific groups with greater risk of psychosocial problems.

• Fashion & Textile Research Journal
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• v.12 no.2
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• pp.156-161
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• 2010

To improve the standard of living of its citizens, local festivals is located in one axis of the new culture. These symptoms shows that there is increasing awareness of traditional culture such as Hanryu. The purpose of this study is to develope the presentative Dress of Andong International Maskdance Festival to stimulate curiosity and participate easily. 24 villages in Andong were present to represent appropriate Dress of Maskdance Festival which have been announced through the fashion show. The characteristics of the maskdance dress which presented in this study has the purpose of making the specialties of each village to tourism resources. Characteristics of the maskdance dress which designed to blend on the mask was as following. (1) Maskdance dress should shown well and must have strong durability of strenuous exercise in maskdance (2) Maskdance dress should be able to get the sympathy of the spectators. (3) Maskdance dress should be sympathetic as modern costumes. (4) Aesthetics as custumes and requirements as product must be met. (5) Acceptance of Andong region's traditional beauty is required. (6) Maskdance dress is likely to require long-term use. (7) Maskdance dress must be able to accommodate a variety of body conditions. Through customer satisfaction survey of 158 spectators and 48 members of fashion show, the relevance of masks and costumes, aesthetic and motility of costumes, commercialization potential, especially costume' motility and functional fitness of clothing sizes was highly evaluated. So maskdance dress or stage costumes as long-term development is likely to be considered. And continued research is needed.

• Biomolecules & Therapeutics
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• v.19 no.1
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• pp.52-58
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• 2011

The inhibitory effect of Chung-Jang-Hwan (C-mix) consisted of Geranium nepalense subsp. thunbergii, Saururus chinensis, and Rubus coreanus were investigated in dextran sulfate sodium (DSS)-induced colitic mice by microarray analysis. Treatment with Cmix improved colitic symptoms, including colon shortening and myeloperoxidase activity. Treatment with DSS alone upregulated the expression levels of inflammation-related genes, including IL-$1\beta$, IL-6, CCL2, CCL4, CCL5, CCL7, CCL8, CCL24, CXCL1, CXCL2, CXCL5, CXCL9 and CXCL10, and other colitis-related genes such as COX-2, PAP, MMP family, S100a8, S100a9 and DEFA1 in mice. However, treatment with C-mix inhibited the expression levels of inflammation-associated genes induced by DSS. The increased expression levels of COX-2 and IL-$1\beta$, representative inflammatory genes, were confirmed by a quantitative realtime polymerase chain reaction analysis. These results indicate that C-mix may ameliorate colitis by the inhibitory regulation of inflammation-associated genes.

• Herbal Formula Science
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• v.18 no.2
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• pp.77-91
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• 2010

The purpose of this study is to expand the prescription usage from internal treatment to external treatment by applying the compatibilities of herbal ingredient for ointment massage therapy. For this, specific cases of usage were investigated in Donguibogam, which is now inscribed on the UNESCO Memory of the World Register, has been not only one of the classics of Korean medical asphere, but has compiled all the contents of the Oriental medical traditions including ointment massage therapy that was completed through different Chinese dynasties, such as Song (宋), Jin(金) and Won(元) by the 17th century. Research results of this study is : 1. Ointment Massage Therapy was used to treat the symptoms of diseases such as ACHI-mun(dental range : 牙齒門), PI-mun(dermal range : 皮門), JECHANG-mun (sore range : 諸瘡門), SO A-mun(pediatrics range : 小兒門). 2. Out of all the manipulations, it is a scrubbing manipulation that used most. 3. Out of all the formulations of ointment massage therapy, it is powder types and ointment types that most representative formulation.