• Journal of Pharmacopuncture
• /
• v.10 no.2 s.23
• /
• pp.31-40
• /
• 2007

Objective : The aim is to examine the effect of Soyeum Pharmacopuncture (SPP) on collagen-induced arthritis (CIA) in DBA/1OlaHsd mice. Methods : To determine the effect of SPP on chronic IFNlammatory joint disease, we induced CIA in DBA/1OlaHsd mice by immunization with bovine type II collagen. Animals were treated with intraperitoneal injection doses of 2 mg/kg of SPP, beginning 3 days before the expected onset of disease symptoms. Inhibitory Effects of SPP were observed by serum levels of TNF-${\alpha}$, and IFN-${\gamma}$,,, or cell proliferation in the spleen cell culture and histological examination of knee joint. Results : In the CIA Mice, serum levels of TNF-${\alpha}$, and IFN-${\gamma}$,, production in the spleen cell culture were reduced. At the histopathological examination of knee joint, chondropathy of cartilage in the synovial joint in the SP group was repaired while compared with control group. Conclusion : These results suggest that the SPP may be effective for the prevention and treatment of rheumatoid arthritis disease.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.13 no.1 s.53
• /
• pp.69-77
• /
• 2009

An underwater structure is made to put with serious damage state by special environmental factors. If this damage phenomena persist, as for the structure, it is generated a structural serious problem because of the corrosion of a reinforcing bar and the loss of the concrete cut end. Repair work of an underwater structure is very harder than repair work in land, and it is actual that certification about a maintenance effect is uncertain. And the existing repair method is applied to a structure damaged with you without verification of a repair effect by a foreign reward and experience. In this study, a repair method about an underwater structure was proposed and observed a behavior characteristic and interface failure of an specimens. and comparison analyzed an effect of a proposed maintenance method.

• The Journal of Internal Korean Medicine
• /
• v.35 no.3
• /
• pp.262-273
• /
• 2014

Objectives: This study was carried out to investigate the protective effect of Coptidis Rhizoma steamed with rice wine (CR) against gastroduodenal mucosal injury through inhibiting inducible nitric oxide synthase (iNOS) activation. Methods: In in vitro experiment, LPS-induced RAW 264.7 macrophages were treated with CR(0.4, 0.6, 0.8, 1.0 mg/ml) and iNOS mRNA expression and nitric oxide (NO) production were measured. In in vivo experiment normal group mice were treated with neither ethanol nor CR. Both control and sample group mice were orally administrated with ethanol. Five hours after ethanol administration control group mice were orally administrated with distilled water, sample group mice were orally administrated with CR. After three days administration, gastroduodenal mucosa of mice was observed histopathologically and iNOS, nuclear factor-kappa B (NF-${\kappa}B$) activation were observed immunohistochemically. Results: In in vitro experiment iNOS mRNA expression and NO production in LPS-induced RAW 264.7 macrophages were decreased by CR dose-dependently. In in vivo experiment, gastroduodenal mucosal injury was repaired by CR and iNOS, NF-${\kappa}B$ activation in gastroduodenal mucosa were decreased by CR. Conclusions: Coptidis Rhizoma steamed with rice wine has a protective effect against gastroduodenal mucosal injury through inhibiting iNOS activation.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.12 no.1
• /
• pp.193-202
• /
• 2008

This paper investigates experimentally the confining effect, strengthening capacity and rebound rate of sprayed Fiber-Reinforced-Polymer (SFRP). From the method, resin and chopped fibers are sprayed separately from the nozzle with high pressure, and then they are attached to the concrete surface, so structure could be repaired. To evaluate the strengthening effect of sprayed FRP, cylindrical specimens and beam specimens were strengthening with SFRP. As main material of FRP, glass fiber and polyester resin are used. To investigate the optimum condition of sprayed FRP, the effects of fiber length, coating thickness, fiber volume ratio and concrete strength were examined. Capacities of sprayed FRP method were also compared to the FRP sheet method. In case of the sprayed FRP, rebound rate is important parameter considering economical efficiency and constructibility, so rebound rate of was discussed. From the test results, optimum conditions of sprayed FRP were determined. SFRP method showed superior strengthening capacities than FRP sheet method.

• Journal of Technologic Dentistry
• /
• v.12 no.1
• /
• pp.113-119
• /
• 1990

The purpose of this study was to investigate the effect of surface tretment on strength of denture repair as influenced by repair resin. Specimens were fabricated from VERTEX heat cured resin. Rectangular specimens($60\times10\times3mm$) were prepared according to the manufacturer's instruction for mixing and packing the resin into molds. Two methods of surface treatment were used and two methods of repair were also tested. The transverse strength of the resin was measured before repair and after repair by AUTOGRAPH testing machine. Six specimens of each category were prepared for testing for a total of 24 specimens. The mean value of the percent of recovery was calculated from the percent of recovery for six specimens. The results were as follows : 1. The mean value of the percent of recovery of each category makes a significant difference statistically one another(p<0.01), and "C" category, chloroform solvent-heat cured resin, has a better effect on repair srength than any other. 2. When no chloroform is used to treat the fractured surface there is no significant difference between the mean values of the percent of recovery influenced by the self curing resin and heat cured resin. But, when chloroform is used there is a significant difference between the two repair resins(p<0.01). 3. When self curing resin repair is used there is no significant difference between repair with and without the surface treatment of chloroform. But, when heat cured resin repair is used the use of chloroform treatment become significant statistically (p<0.01).

• The Journal of Dong Guk Oriental Medicine
• /
• v.8 no.1
• /
• pp.117-131
• /
• 1999

Yangkyuksanhoa-tang is frequently used for cerebrovascular accident(CVA). The present study was performed to investigate the effect of Yangkyuksanhoa-tang on the peri vascular immunoreactive nerve fiber of the basilar artery after experimentally induced subarachnoid hemorrhage(SAH). Sprague Dawley rats weighing between 350-400g were used. The SAH induced by injection of the fresh autologus heart blood(0.3-0.4ml) into the cisterna magna through the posterior atlanto-occipital membrane. Sample group was given a $3.3m{\ell}/kg/day$ of Yangkyuksanhoa-tang extracts for 2 days after SAH. The experimental animals divided into 48hrs after SAH. The changes of perivascular immunoreactive nerve fiber was examined by using indirect immunofluorescence method. The meshlike perivascular nerve fiber appeared in the basilar artery of normal rats. In basilar artery of SAH elicitated rat, the distribution of calcitonin gene-related peptide (CGRP)-immunoreactivity(IR) and vasoactive intestinal polypeptide(VIP)-IR of the perivascular nerve fiber were remarkably diminished, also dopamine beta hydroxylase(DBH)-IR, neuropeptide Y(NPY)-IR and serotonin-IR were diminished. In SAH elicitated rat with Yangkyuksanhoa-tang treatment, the CGRP-IR and VIP-IR degree were repaired as well as normal rat's, but DBH-IR, NPY-IR and serotonin-IR had no changes. These results provide the basic data to investigate the effect of Yangkyuksanhoa-tang on the vasospasm after SAH.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.22 no.3
• /
• pp.554-561
• /
• 1998

Vehicle body structures are formed by thousands of spot welds and fatigue failure of vehicle structures occur near the spot welds after driving a long way at a durability test road. It is necessary to know accurately the reason of the fatigue failure of the spot weld in the developing stage in order to reinforce it. Many investigations have been done regarding the strength of spot welded joints, contributing to understand its fatigue strength. In developing process, a fatigue failed spot welded area can be repaired by $CO_2$ welding or another method to continue the test. To know the effect of reinforcing these welds, several methods of welding were analyzed and compared to spot welding. With the results of this test, the appropriate repair method can be used instead of spot welding during the development of new car and best design guide can be given for the strength. In this study, fatigue and static tensile tests are made and microstructure is investigated for the purpose of estimating the strength of welded joints by using spot welded and $CO_2$ plug welded specimens. The tested specimens are of two types : Tensile-shear type(TS) and L-tension type(LT).

• Journal of the Korea Fashion and Costume Design Association
• /
• v.14 no.3
• /
• pp.135-146
• /
• 2012

This study aims to analyze the preference of jacket design, practical factors regarding jacket-wearing and purchasing behavior for korean baby- boom generation women. The results are as follows: 1. According to the outfit preference survey, the silhouette most preferred by female baby boomers is the "X-line Silhouette", "hip length", "slightly fitted and well fitted". The preferred jacket colors for different seasons were grey and beige for spring, white and light yellow for summer, khaki and brown for fall and black and dark grey for winter. 2. According to the survey on factors to consider when purchasing jackets, 52% indicated that they "almost never" or "occasionally" had their jackets repaired after purchasing them. When purchasing jackets, the highest expected effect of looking younger by wearing a jacket was "looking 4-5 years younger". 3. According to the survey on price demands, the average purchase price for jackets was 160,000~200,000 won (27.80%) followed by 210,000~350,000 won (25.64%) and a significant difference existed based on the purchasers' economic activities.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.25 no.12
• /
• pp.2091-2099
• /
• 2001

Fatigue crack growth behavior of inclined cracked Al 6061-T6 thick aluminum plate(6mm) repaired with the bonded composite patch was studied. A 0°inclined crack bonded reinforced composite patch and 15°, 30°, 45°, 60°inclined crack plates were tested. The effect of patch and inclined angle were studied and compared to each other. Also we investigated to the crack propagation direction and debonding behavior during the fatigue crack growth test. In this paper. a study was con(ducted to get an fatigue life, fatigue crack growth ratio and crack growth direction. Finally, the effectiveness of composite patch on inclined cracked plate was investigated. The results demonstrated thats there was a definite variation in fatigue life and fatigue crack growth behavior depending on the inclined crack angle.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.25 no.12
• /
• pp.2070-2077
• /
• 2001

An experimental investigation of the effect of composite patching repair was conducted to characterize the fatigue crack growth behavior in thick A16061-T6 (6mm) panels with single bonded patch by fiber reinforced composite patch. Four patch lengths and no patch plate were examined. An analytical procedure, involving three-dimensional finite element method having three layers to model cracked aluminum plate, epoxy by adhesive and composite Patch, is calculated the stress intensity factors. From the calculated stress intensity factors, the fatigue crack growth rates are obtained. At the single patching type, different fatigue crack growth ratios through the palate thickness were investigated by using the experimental and analytical results. The results demonstrated that there was a definite variation in fatigue life depending on the size of composite patch. While crack reached the patch end, retardation of crack growth was also revealed in the bonded repair.