• Journal of Chest Surgery
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• v.36 no.9
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• pp.646-650
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• 2003

Many surgical techniques for ischemic mitral regurgitation (IMR) have been used with their excellent results and advantages. Here, we report our simple posterior annuloplasty techniques using vascular graft strip with their early results. Material and Method: Twenty two patients (13 male) underwent the operations for IMR (excluding the papillary muscle rupture) from December 2001 to January 2003. Preoperative risk factors were low ejection fraction (<35％, n=9), hypertension (n=13), diabetes (n=9), and renal failure (Cr>2.5, n=4). The wide dissection beneath the both vena cavae and interatrial groove after bicaval cannulation enabled the easy exposure of mitral valve even in the small left atrium. After eight or nine interrupted sutures in posterior annulus for anchoring the 6 mm width vascular graft strip, symmetric (n=8) or asymmetric (n=14) annuloplasty were done. Combined surgeries were CABG (n=21), Dor procedures (n=3), tricuspid valve annuloplasty (n=1), Maze operation (n=1), and aorto-right subclavian artery bypass (n=1). Result: Except for one surgical mortality, all the patients were doing well and the mean grade of regurgitation was decreased from 2.95 to 0.88, however the ejection fraction had not changed significantly just before discharge. Post-operative valve function evaluated before discharge revealed no residual regurgitation in 8 (including 1 patient with mild stenosis due to over reduction), minimal in 11, mild in 2, and mild to moderate regurgitation in 1. One patient who had ischemic cardiomyopathy and renal failure died of the arrhythmia during the hemodialysis. Conclusion: These observations suggest that the annuloplasty with vascular graft strip could be a safe and cost effective techniques for ischemic mitral regurgitation. However, the long term evaluation for the mitral valve function should be defined for the final conclusion.

• Journal of Navigation and Port Research
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• v.37 no.1
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• pp.113-121
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• 2013

IMO(International Maritime Organization) is existed the movement for revising ISM Code so that the maintenance history and the trouble information given trading in a ship can be transferred. An empirical analysis was made on the influence that will have upon shipping industry through surveying on the recognition on ISM Code revision in employees of the relevant field and on the expected problems given being amended ISM Code as the above. In conclusion, the positive effect is judged to be more in the aspect of ship safety, which is the aim of ISM Code, rather than the negative effect, which may take place given being revised ISM Code. In other words, the clean market can be formed through this because fairness is maintained on both sides given trading in a ship by which opening the maintenance record and the trouble history is applied equally to a buyer and a seller. Ships can be reduced a loss of time and cost in preventing similar problems and seeking solution that may appear in important equipments, through this maintenance record. Also, based on these materials, it comes to be available for analyzing a risk of ship and preventing and managing a risk, thereby being increased ability of maintenance and repair in a ship, resulting in being judged to likely contributing to ship safety and environmental-pollution prevention.

• Journal of the Korean GEO-environmental Society
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• v.16 no.2
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• pp.45-52
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• 2015

To minimize the cost of maintenance, repair and over-design of track substructure, an accurate evaluation of strength and stiffness of the track substructure is necessary. In this study, a cone penetrometer with impact penetration rod (CPI) is developed for the evaluation of track substructure. For applicability test, the chamber and field tests were performed. As the experimental results of the CPI, dynamic cone penetration endex (DCPI), cone tip resistance ($q_c$), friction resistance ($f_s$) and friction ratio (Fr) were obtained. In the chamber test, the experimental results show reasonable values for the simulated track substructure. In the field test, the CPI clearly detects the interface between the ballast and the subgrade. Also, discontinuous layers are detected in the subgrade. It is expected that the developed CPI may be an effective tool for the evaluation of track substructure by evaluating the ballast layer by dynamic penetration and the subgrade by static penetration of the inner rod.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.34 no.2
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• pp.377-387
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• 2014

This study mainly treats a new type of the bracing friction damper system, which is able to minimize structural damage under earthquake loads. The slotted bolt holes are placed on the shear faying surfaces with an intention to dissipate considerable amount of friction energy. The superelastic shape memory alloy (SMA) wire strands are installed crossly between two plates for the purpose of enhancing recentering force that are able to reduce permanent deformation occurring at the friction damper system. The smart recentering friction damper system proposed in this study can be expected to reduce repair cost as compared to the conventional damper system because the proposed system mitigates the inter-story drift of the entire frame structure. The response mechanism of the proposed damper system is firstly investigated in this study, and then numerical analyses are performed on the component spring models calibrated to the experimental results. Based on the numerical analysis results, the seismic performance of the recentering friction damper system with respect to recentering capability and energy dissipation are investigated before suggesting optimal design methodology. Finally, nonlinear dynamic analyses are conducted by using the frame models designed with the proposed damper systems so as to verify superior performance to the existing damper systems.

• Journal of Plant Biotechnology
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• v.44 no.1
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• pp.89-96
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• 2017

The CRISPR/Cas9 is a core technology that can result in a paradigm for breeding new varieties. This study describes in detail the sgRNA design, vector construction, and the development of a transgenic plant and its molecular analysis, and demonstrates how gene editing technology through the CRISPR/Cas9 system can be applied easily and accurately. CRISPR/Cas9 facilitates targeted gene editing through RNA-guided DNA cleavage, followed by cellular DNA repair mechanisms that introduce sequence changes at the site of cleavage. It also allows the generation of heritable-targeted gene mutations and corrections. Here, we present detailed procedures involved in the CRISPR/Cas9 system to acquire faster, easier and more cost-efficient gene edited transgenic rice. The protocol described here establishes the strategies and steps for the selection of targets, design of sgRNA, vector construction, and analysis of the transgenic lines. The same principles can be used to customize the versatile CRISPR/Cas9 system, for application to other plant species.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• autumn
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• pp.529-532
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• 2003

Efficiency and efficient management on maintenance/repair/operation (MRO) phase is getting important with advance in technologies and complex functionalities of building and facility. Using software systems as well as advanced hardware systems in MRO area is spreading along with this trend to take advantage of information technology. Information of building and facility for MRO phase is derived from engineering/procurement/construction (EPC) phase. But most current commercial software systems in EPC and MRO are focusing on their own phase, which arise lack of consistency of information from EPC to MRO phase. But, the information system now used at the MRO phase stop flowing the building and the facilities information and then newly create. Moreover, from all asset management point of view, asset particulars such as the structures and equipments are different the value fluctuation. In order to reflect these information rationally, the construction costs are correctly distributed and the initial price of the asset particulars have to be estimated. In this study, develop the information model which can apply the cost information at the EPC phase to the MRO phase.

• Korean Journal of Construction Engineering and Management
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• v.5 no.1 s.17
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• pp.99-106
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• 2004

Efficiency and efficient management on maintenance/repair/operation (MRO) phase is getting important with advance in technologies and complex functionalities of building and facility, Using software systems as well as advanced hardware systems in MRO area is spreading along with this trend to take advantage of information technology. Information of building and facility for MRO phase is derived from engineering/procurement/construction (EPC) phase. But most current commercial software systems in EPC and MRO are focusing on their own phase, which arise lack of consistency of information from EPC to MRO phase. But, the information system now used at the MRO phase stop flowing the building and the facilities information and then newly create. Moreover, from an asset management point of view, asset particulars such as the structures and equipments are different the value fluctuation. In order to reflect these information rationally, the construction costs are correctly distributed and the initial price of the asset particulars have to be estimated. In this study, develop the information model which can apply the cost information at the EPC phase to the MRO phase.

• Journal of Distribution Science
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• v.8 no.3
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• pp.5-15
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• 2010

Business corporations have become specialized and on the basis of various interests try to strengthen their competitiveness through a cooperative system of purchase, distribution, service and IT technology. And an advanced Internet-based electronic commerce has witnessed explosive growth and a business-to-business (B2B) electronic commerce. Through E-marketplace. business corporations achieve such diverse utilities as expenditure curtailment, process reduction and prime cost reduction. And with business depression worldwide and soaring prices of materials, many business corporations consider the introduction of comprehensive purchase of MRO (maintenance, repair and operation) materials. The Purpose of this study was to examine the definition of B2B E-marketplace and the utilities of MRO commerce correctly focusing on an empirical analysis of cases of MRO supply and purchase business corporations. The indications acquired from this research results are as follows. Firstly, as for MRO integrated purchase under the characteristics of the market environment, it had to use the supplier obligatorily through the integrated purchase on the level of CEO's decision-making or the group rather than the voluntary will of the purchasing department or the procurement department. Secondly, as for the present B2B E-marketplace MRO purchase, the purchasing agency business has formed the mainstream, but it is aiming at the diversification of the benefit by supplementing/correcting the business model such as category type, mediation business type, MRO-type advancing in the store inclusive of the purchasing agency business, keeping pace with the potential market of MRO. Thirdly, as for analysis of the products, the purchaser wants more various products and assortment of goods than those of the present time, and also to be provided with the precise product information. Especially, as the importance of the product sourcing becomes high, the whole energy has been bestowed on acquirement of the excellent suppliers. Fourth, as for use of B2B E-marketplace MRO integrated purchasing system, there are the purchasing companies complaining the inconvenience even until now, and there is the demerit spending the long time during the image move and the process treatment. It shall try to shorten the searching time and the process treatment time as the system is centered on the purchaser. In order to enhance the efficiency of MRO E-marketplace purchase, followings must be considered: First, because the importance of product sources ever increases, an excellent supplier must be secured earnestly. Second, the time of process must be reduced focusing on purchasers. B2B E-marketplace will increase and diversify electronic commerce continuously. Through MRO E-marketplace, business corporations will reduce expenditure, achieve a transparent and speedy trade, and purchase products of fine quality, thus establishing a most effective market. In addition, in this study the investigator brings focus into MRO which has not been clearly discussed in the academic and business world so far and intensively highlights an indirect material-oriented expenditure curtailment effect. By taking all the aspects of supplier, purchaser and practical economical value into account, the investigator presents a strategic direction for the successful comprehensive purchase of B2B MRO.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.473-476
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• 2008

Due to the pursuit of high function and international price increase in the field of construction, the application of the secondary product using cement is on the increase gradually in the construction industry in the pursuit of economic cost reduction by the shortening of the construction time like Expediting and the dry construction method at the same time. However, it is in very urgent situation of measures to improve the structural performance or durable performance because it is limited for use in terms of panel in interior exterior building or functional repair reinforce as yet. Accordingly, this study is to investigate applicability of permanent Formwork like mould with the structural performance or excellent durable performance in the field of construction, and to derive optimum mixture in the performance and quality of manufacture. As a result of analysis comparison with the dynamic and durable properties of vacuum extrusion molding high toughness cement panel according to the mixture of four conditions, this study has found that the test body of mixing ECC-DP3 using small filler and large granulated blast furnace slag and powder flame retardant had excellent relative hardness and bending stress strain. The durable performance has shown excellent tendency by the decrease of porosity and enhancement of water-tightness.

• Journal of the Korea Concrete Institute
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• v.17 no.3 s.87
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• pp.329-334
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• 2005

The use of Polymer Concrete (PC) is growing very rapidly in many structural and construction applications such as box culverts, hazardous waste containers, trench lines, floor drains and the repair and overlay of damaged cement concrete surfaces in pavements, bridges, etc. However, PC has a defect economically because resin which be used for binder is expensive. Therefore the latest research is being progressed to replace existing resin with new resin which can reduce the high cost. Here, Polymer concrete using the recycled PET(polyethylene terephthalate) has some merits such as decrease of environmental destruction, decrease of environmental pollution and development of new construction materials. The variables of this study are amount of resin, curing condition and maximum size of coarse aggregate to find out mechanic properties of this. Stress-strain curve was obtained using MTS equipment by strain control. The results indicated that modulus of elasticity was increased gradually in an ascending branch of curve, as an increase of resin content. Compressive strength was the highest for resin content of $13\%$. And Compressive strength was increased as maximum size of coarse aggregate increases. The strain at maximum stress increases with an increase of resin content and size of coarse aggregate. For the descending branch of stress-strain curve the brittle fracture was decreased when it was cured at the room temperature compared to high temperature.