• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1799-1802
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• 2012

Objective: We aimed to analyze the association between excision repair cross-complementing rodent repair deficiency complementation group 1 (XRCC1) and ovarian cancer risk. Methods: We performed a hospital-based case-control study with 155 cases and 313 controls in China. All Chinese cases with newly diagnosed primary ovarian cancer between May 2005 to May 2010 in our hospital were invited to participate within 2 months of diagnosis. Controls were randomly selected from people who requested general health examinations in the same hospital during the same period. SNPs in EXCC1, ERCC1 C8092A and ERCC1 T19007C, were analyzed by PCR-RFLP method. Results: We observed a non-significantly increased risk of ovarian cancer among individuals with ERCC1 8092TT compared with those with the 8092CC genotype (adjusted OR=1.55, 95% CI%=0.74-2.97). Moreover, 19007TT genotype carriers also showed a non-significant increased risk of ovarian cancer over those with the 19007CC genotype (adjusted OR=1.78, 95% CI%=0.91-3.64). Conclusion: Our firstly investigation of links between polymorphisms in the ERCC1 gene and the risk of ovarian cancer in Chinese population demonstrated no significant association. Further large sample studies in Chinese populations are needed.

• Journal of the Korean Arthroscopy Society
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• v.10 no.2
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• pp.173-177
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• 2006

Purpose: To evaluate the efficacy of arthroscopic Bankart repair using suture anchors for treatment of traumatic anterior instability of shoulder joint. Materials and Methods: We performed arthroscopic Bankart repair using suture anchor in 90 cases and evaluated the results with the functional grading system of Rows and Zarins after patients were followed up for more than 24 months. Results: Combined pathologies identified under arthroscopy were Hill-sachs lesion in 46 cases, SLAP lesion in 12 cases, Rotate cuff lesion in 7 cases. The results were excellent or good in 82(91.1%) cases and redislocation was happened only 3 cases. Conclusion: We concluded that arthroscopic Bankart repair with suture anchors is one of the reliable and effective method for recurrent shoulder dislocation with Bankart lesion.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.12
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• pp.1684-1691
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• 2016

Erasure codes have recently been applied to distributed storage systems due to their high storage efficiency. Regenerating codes are a kind of erasure codes, which are optimal in terms of minimum repair bandwidth. An (n,k,d)-regenerating code consists of n storage nodes where a failed node can be recovered with the help of the exactly d numbers of surviving nodes. However, if node failures occur frequently or network connection is unstable, the number of helper nodes that a failed node can contact may be smaller than d. In such cases, regenerating codes cannot repair the failed nodes efficiently since the node repair process of the codes does not work when the number of helper nodes is less than d. In this paper, we propose an operating method of regenerating codes where a failed node can be repaired from ${\bar{d}}$ helper nodes where $$k{\leq_-}{\bar{d}}{\leq_-}d$$.

• Archives of Plastic Surgery
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• v.37 no.1
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• pp.31-36
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• 2010

Purpose: The primary goal of palatoplasty is to enable normal speech with harmonious growth of face. Some children who had palatoplasty display typical findings of transverse maxillary deficiency requiring orthodontic widening of the maxilla. Levi (2009) described a cleft palate repair coupled with pedicled buccal fat pad flaps to cover bone exposed areas of the hard palate. Hence we report clinical experiences of cleft palate repair using pedicled buccal fat pad flap. Methods: Four Veau class II and a Veau class I cleft palate patients underwent palatoplasty with buccal fat pad flap by single surgeon from April 2009 to August 2009. Two patients received 2-flap palatoplasty and three patients 1-flap palatoplasty, respectively. After the cleft palate repair, sharp mosquito scissors was placed in the superior buccal sulcus just lateral to the maxillary tuberosity and inserted directly through the mucosa resulting in buccal fat pad extrusion. The elevated flap was moved to cover mucoperiosteal defect in hard palatal area. Results: Five patients underwent primary palatoplasty using buccal fat pad flap. Flap harvest and inset took on average 9 minutes per flap. Mucosal epithelization took 18 days on average. No patients had complications related to the buccal fat pad flap. Conclusion: Buccal fat pad pedicled flap has significant potential to function as an added vascularized tissue layer in cleft palate repair and we can expect better growth of maxilla with this method although longer duration of follow-up was unavailable.

• Journal of the Korea institute for structural maintenance and inspection
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• v.14 no.2
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• pp.89-96
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• 2010

This study presented the analytical evaluation model effective in the concrete structure repaired with a patching material. The model considered the effect of the repair material on carbon dioxide penetration into the repaired concrete as evaluating the remaining service life of the CO2-deteriorated concrete structure after repair. The diffusion profiles of carbon dioxide as well as the carbonated concrete were effectively able to be modelled with analytical method based on Fick's 1st diffusion law. The evaluation of the model equation showed the good result and rational process quantitatively and numerically to evaluate the remaining service life of the repaired concrete structure after repair.

• Korean Journal of Environmental Biology
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• v.23 no.1
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• pp.21-26
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• 2005

Cell response to genotoxic agents is complex and involves the participation of different classes of genes including cell cycle control, DNA repair and apoptosis. In this report, we presented a approach to characterize the cellular functions associated with the altered transcript profiles of MCF-7 exposed to low-dose in vitro gamma-irradiation. We used the method of human 2.4 k cDNA microarrays containing apoptosis, cell cycle, chromatin, repair, stress and chromosome genes to analyze the differential gene expression characterization that were displayed by radiation-exposed cell, human breast carcinoma MCF-7 cell line, such as 4 Gy 4 hr, 8 Gy 4 hr, and 8 Gy 12 hr. Among these genes, 66 were up-regulated and 49 were down-regulated. Specific genes were concomitantly induced in the results. Cyclin dependent kinase 4 (Cdk4) is induced for starting the cell cycle. This regulation is required for a DNA damage­induced G1 arrest. In addition to, an apoptotic pathways gene Bcl-w was concomitantly induced. Mismatch repair protein homologue-l (hMLH1), a necessary component of DNA mismatch protein repair (MMR), in G2-M cell cycle checkpoint arrest. The present study provides new information on the molecular mechanism underlying the cell response to genotoxic stress, with relevance to basic and clinical research.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.1
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• pp.122-129
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• 2019

Due to its nature the manufacturing industry faces a cyclical economy, and therefore there is an urgent need for a companion industry to cope with this cyclic pattern in the long run. The sector suitable for meeting this demand is the repair and shipbuilding industry. In order to operate a shipbuilding repair business, a floating dock is indispensable, and most obsolete floating docks were imported from overseas and operated through repair/maintenance. However, there is no precise guideline for floating dock safety, and most models have been in use for at least 30 years without being required to enter classification at the time of operation. In this study, structural strength analysis was carried out using measured thickness information of aged floating docks, and the residual structural strength of floating docks in operation was analyzed. The main results derived from this study can be referred to as guidelines for the review of the structural safety of similar equipment, and it is expected that an optimal solution will be found within a short time using this method for repair/maintenance.

• Journal of Yeungnam Medical Science
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• v.40 no.2
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• pp.187-192
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• 2023

Background: This study aimed to present the short- and midterm outcomes after complete atrioventricular canal defect (CAVC) repair using a single-patch technique. Methods: This study included 30 children who underwent surgical correction of the CAVC using a single-patch technique. Results: The median age of the patients was 5.7 months (interquartile range [IQR], 5.0-7.5 months), and 23 patients (76.7%) had type A CAVC. Fourteen patients (46.7%) were female and 17 (56.7%) had been diagnosed with Down syndrome. The in-hospital mortality rate was 0%. No deaths were observed during a median follow-up of 4 years (IQR, 3.5-5.0 years). Patients without Down syndrome were associated with late moderate mitral regurgitation (MR) (p=0.02). Late MR less than moderate degree was observed in 96.6%, 78.5%, and 50% of patients after 2, 4, and 5 years of follow-up, respectively, while late tricuspid valve regurgitation less than moderate degree was observed in 96.7%, 85.9%, and 59.0% of patients after 2, 4, and 6 years of follow-up, respectively. After a median follow-up of 4 years, only one patient had required surgical repair of a left ventricular outflow tract obstruction, which occurred 26 months after the first operation. Multivariable logistic regression analysis adjusted for the type of CAVC, sex, Down syndrome, age, and weight revealed that the absence of Down syndrome was a risk factor for late moderate MR (MR-2) (odds ratio, 0.05; 95% confidence interval, 0.006-0.50; p=0.01). Conclusion: A single-patch technique for CAVC surgical repair is a safe method with acceptable short- and midterm results.

• Journal of the Korea institute for structural maintenance and inspection
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• v.13 no.6 s.58
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• pp.88-96
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• 2009

In this Study, FR-ECC(Fire Resistance Engineered Cementitious Composites) in which at same time it can improve the endurance and fire-resistance efficiency of a Structure was developed, and the experimental study such as thermal characteristic, Fire-resistance efficiency, and etc was performed for using FR-ECC as the repair materials for building and civil Structure. Moreover, it was evaluated about the field applicability of FR-ECC. As a result, FR-ECC is superior to the existence fire resistance repair mortar in strength and durability property. Also, FR-ECC was exposed to have the characteristic of being excellent than existence fire resistance mortar in the field applicability.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.128-134
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• 2016

Estimating the repair and reinforcement (R&R) costs for each bridge member is essential for managing the life cycle of a bridge using a bridge management system (BMS). Representative members of a bridge were defined in this study, and detailed and representative R&R methods for each one were drawn in order to develop a systematic maintenance cost model that is applicable to the BMS. The unit cost for each detailed R&R method was established using the standard of estimate and historical cost data, and a systematic procedure is presented using an integration program to enable easy renewal of the R&R unit cost. Also, the average unit cost of the representative R&R methods was calculated in the form of a weighted average by considering the unit cost and application frequency of each detained R&R method. The appropriateness of the drawn average unit cost was reviewed by comparing and verifying it with the previous historical unit cost. The suggested average R&R unit cost can be used to review the validity of the required budget or the appropriateness of the R&R performance cost in the stage to establish the bridge maintenance plan. The results of this study are expected to improve the reliability of maintenance cost information and the rationality of decision making.