• Title/Summary/Keyword: Rep. of Korea

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Inspection on the acoustic output of the focused extracorporeal focused shock wave therapeutic devices approved by MFDS (식약처에서 허가된 집속형 ESWT 치료기의 음향 출력 분석)

  • Choi, Min Joo;Jeon, Sung Joung;Kwon, Oh Bin;Lee, Min Young;Cho, Jin Sik;Kim, Han Soo;Maeng, Eun Ho
    • The Journal of the Acoustical Society of Korea
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    • v.39 no.4
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    • pp.303-317
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    • 2020
  • Extracorporeal Shock Wave Therapy (ESWT) is an innovative treatment in chronic musculoskeletal pain management and cardiovascular diseases. In this study, we surveyed the acoustic shock wave outputs from the domestically used focal type ESWT devices. The survey data were collected through 30 technical documents registered to the Ministry of Food and Drug Safety (MFDS), Rep. Korea. The results show that the focusing geometry varies largely, 5 mm to 65 mm in the focal length, 3 mm to 30 mm in focal width, and 4 mm to 108 mm in focal depth. The maximum positive pressure (P+) ranges from 7 MPa to 280 MPa, the focal Energy Flux Density (EFD) from 0.0035 mJ/㎟ to 35 mJ/㎟, and the energy per pulse (E) from 0.737 mJ to 80.86 mJ. All domestic PE-type (five) and one EM-type domestic devices included in the analysis of the correlation between P+ and EFD are shown to be far beyond the usual ranges and do not comply with expected correlation so that the reliability of their data was suspected. For the suspected, post-performance tests are required by a recognized testing agency. MFDS guidelines need to be revised so that the pass criteria for the shock wave acoustic outputs can be based on the clinical tests for indications.

Acoustic outputs from clinical ballistic extracorporeal shock wave therapeutic devices (임상에서 사용중인 탄도형 체외충격파 치료기의 음향 출력)

  • Cho, Jin Sik;Kwon, Oh Bin;Jeon, Sung Joung;Lee, Min Young;Kim, Jong Min;Choi, Min Joo
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.5
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    • pp.570-588
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    • 2022
  • We scrutinized the acoustic outputs from the 70 shock wave generators of the 15 product models whose technical documents were available, among the 46 ballistic extracorporeal shock wave therapeutic devices of 11 domestic and 6 foreign manufacturers, approved by the Minster of Food & Drug Safety (Rep. Korea). We found that the acoustic Energy Flux Density (EFD), the most popular exposure parameter, was different by up to 563.64 times among shock wave generators at their minimum output settings and by up to 74.62 times at their maximum settings. In the same product model, the EFD was shown to vary depending on shock wave transmitters by up to 81.82 times at its minimum output setting and by up to 46.15 times at its maximum setting. The lowest EFD 0.013 mJ/mm2 at the maximum output settings was much lower (2.1 %) than the maximum value 0.62 mJ/mm2 at the minimum settings. The Large acoustic output differences (tens to hundreds of times)from the therapeutic devices approved for the same clinical indications imply that their therapeutic efficacy & safety may not be assured. The findings suggest the regulatory authority to revise her guideline to give clearer criteria for clinical approval and equality in performance, and recommend the authority to initiate a post-approval surveillance as well as a test in conformance between the data in technical documents and the real acoustic outputs clinically used.

The Influence of Insulation Wraps on the Temperature Change of Kiwifruit Trunk Surface During Winter (월동 피복재 종류에 따른 참다래 주간부 표면 온도변화)

  • Kwack, Yong-Bum;Kim, Hong Lim;Kim, Seong-Cheol;Kim, Mok-Jong;Lee, Yong-Bok
    • Korean Journal of Environmental Agriculture
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    • v.33 no.4
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    • pp.403-408
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    • 2014
  • BACKGROUND: Kiwifruit is a warm-temperate, deciduous fruit tree. It is sensitive to frost or freeze damage during winter. Therefore, the farmers cover kiwifruit trunk with rice straw to preclude freeze injury. This study was conducted to evaluate trunk wraps for protection of freeze injury of kiwifruit (Actinidia deliciosa) vines. METHODS AND RESULTS: The experimental orchard was located in Sacheon (lat. $34^{\circ}56'N$, long. $128^{\circ}03'E$) of Gyeongsangnam-do, South Korea. The vines were 5-6-year-old 'Hayward'. Two wrap materials, rice straw and silver-cushioned mat (reflective foil-coated, plastic-foamed mat, Ganan Industry, Rep. of Korea) were evaluated for their heat-retaining ability. The trunks of kiwifruit vines were wrapped in late December, and the wraps were removed in mid-April the following year (2012/13 and 2013/14). Temperature inner wraps were recorded from January to March in 2013 and 2014 by WatchDog 2450 (Spectrum Technologies, Inc., USA). In 2013, the lowest ambient temperature of January and February was $-10.2^{\circ}C$, $-10.9^{\circ}C$, respectively. The lowest temperature of inner-wrap of silver -cushioned mat was $-6.3^{\circ}C$, $-2.6^{\circ}C$ in January and February, respectively. However, rice straw showed $-9.8^{\circ}C$ and $-9.9^{\circ}C$ in its lowest value of January and February. And also silver cushioned mat appeared to be superior to rice straw in its ability of heat-retaining during night time.

Distribution of Antimicrobial Resistant Genes in Acinetobacter calcoaceticus-baumannii Complex Isolated from Clinical Specimens in Chungcheong, Korea (충청지역의 임상검체로부터 분리된 Acinetobacter calcoaceticus-baumannii Complex를 대상으로 항균제 내성 유전자 비교분석)

  • Sung, Ji Youn
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.427-434
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    • 2017
  • Species that belong to the Acinetobacter calcoaceticus-baumannii (Acb) complex are major causes of hospital-acquired infections. They are important opportunistic pathogens. These species are usually multidrug resistant (MDR), and the therapeutic options to treat the infections caused by these species are limited. In the present study, we investigated fluoroquinolone resistance mechanisms in 53 ciprofloxacin resistant Acinetobacter species isolates in Chungcheong, Korea. Antimicrobial susceptibilities were determined using the disk-diffusion method. Detections of genes and identification of mutations associated with fluoroquinolone resistance were carried out using PCR and DNA sequencing. In our study, 47 out of 53 ciprofloxacin resistant Acinetobacter isolates harbored sense mutations at the 83rd residue (serine to leucine) in the gyrA gene as well as at the 80th residue (serine to leucine) in the parC gene. Among the 47 isolates harboring sense mutations in gyrA and parC gene, 44 isolates were A. baumannii and 3 isolates were A. pittii. Plasmid-mediated quinolone resistance (PMQR) determinants were detected in isolates in our study. Among the 46 ciprofloxacin resistant A. baumannii isolates, 41 showed type A, B, or F banding patterns on their REP-PCR profiles. This result suggests that clonal relation and horizontal spreading of the bacterial isolates have been around hospitals in Chungcheong area. To prevent colonization and disseminations of fluoroquinolone resistance Acb complex isolates, continuous investigation and monitoring of antimicrobial resistant determinants of MDR isolates are needed.

Molecular Characterization of the Bacterial Community in Activated Sludges by PCR­RFLP (PCR-RFLP 방법을 이용한 활성 슬러지의 세균군집 분석)

  • Lee Hyun-Kyung;Kim Jun-Ho;Kim Chi-Kyung;Lee Dong-Hun
    • Korean Journal of Microbiology
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    • v.40 no.4
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    • pp.307-312
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    • 2004
  • Diversity of the bacterial communities and the relation between community structure and components of waste­water were analyzed by 16S rRNA-based molecular techniques. Clone libraries of the 16S rDNAs from the sludges were constructed by PCR and cloning. The 1,151 clones from a sludge sample of sewage treatment plant were clustered into 699 RFLP phylotypes and the 1,228 clones from the wastewater disposal plant of chemical industry were clustered into 300 RFLP phylotypes. Shannon-Weiner diversity indices of two sampling sites were 8.7 and 6.1, indicating that the bacterial community structure of sewage treatment plant was more diverse than that of wastewater disposal plant of chemical industry. Forty clones belonging to predominant RFLP types were selected and sequenced. Seventy percent (28 clones) of the sequenced clones were related to the uncultured bacteria in public databases. The ${\beta}-Proteobacteria$ dominated in the bacterial communities of investigated two sludge samples. 16S rDNA sequences of the sewage treatment plant were similar to those of other activated sludges, while the bacterial community in wastewater disposal plant of chemical industry rep­resented the strains identified from high-temperature, anaerobic, hydrocarbon-rich, and sulfur-rich environ­ments. This result suggested that bacterial communities depended upon the components of wastewater.

The Exploitation of World Fishery Resources for 10 Years under the New Regime in the Sea (신해양질서 10년후 세계어업자원 이용동향)

  • 이장욱;허영희
    • The Journal of Fisheries Business Administration
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    • v.23 no.1
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    • pp.43-87
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    • 1992
  • In this paper, state of exploitation of world fishery resources after 10 years under the new regime in the sea, called the era of exclusive economic zone (EEZ) expending up to a 200 nautical miles from coastal line, was reviewed to determine effect from establishing EEZ in the world fishery production and its export/import volume based on the fishery statistics annually published by the Food and Agriculture Organization (FAO) of United Nation. The world total production from marine living resources had a trend showing a waned increase during 1970's when most of coastal states were translated into the reality of EEZ. From mid-1980's onwards, it increased rapidly, reaching about 85 million tons . Such increase in production was basically from the Pacific Ocean, accounting for more than 60% of the world total production. Fishing areas where showed increase in the production after the new regime in the sea were the southwestern Atlantic (FAO area 41) , the eastern Indian (FAO area 57) and the whole fishing areas in the Pacific except the eastern central Pacific (FAO area 77). Increase in the production from distant-water fishing countries came from the regions of the southwest Atlantic (FAO area 41) and the southwest Pacific (FAO area 81) . The production from coastal states was up from the regions of the eastern Indian (FAO area 57) , the northwest and northeast Pacific (FAO areas 61 and 67) and the southeast Pacific (FAO area 87) . It was likely that the exploitation of the fishable stocks was well monitored in the areas of the northwest Atlantic (FAO area 21) , the eastern central Atlantic (FAO area 34) and the northeast Pacific (FAO area 67) through appropriate management measures such as annual harvest level, establishment of total allowable catch etc. The marine fisheries resources that have made contribution to the world production, despite expansion of 200 EEZ by coastal states, were sardinellas, Atlantic cod, blue whiting and squids in the Atlantic Ocean : tunas which mainly include skipjack, yellowfin and bigeye tuna, croakers and pony fishes in the Indian Ocean : and sardine, Chilean pilchard, Alaska pollock, tunas (skipjack and yellowfin tuna) , blue grenadier and blue whiting including anchoveta in the Pacific Ocean. It was identified that both fishery production and its export since introduction of the new regime in the sea were dominated by such coastal states as USA, Canada, Indonesia, Thailand, Mexico, South Africa and Newzealand. But difficulties have been experienced in the European countries including Norway, Spain, Japan and Rep. of Korea. Therefore, majority of coastal states are unlikely to have yet undertaken proper utilization as well as rational management of marine living resources in their jurisdiction during the last two decades. The main target species groups which led the world fishery production to go up were Alaska pollock, cods, tunas, sardinellas, chub and jack mackerel and anchoveta. These stocks are largely expected to continue to contribute to the production. The fisheries resources which are unexploited, underexploited and/or lightly exploited at present and which will be contributed to the world production in future are identified with cephalopods, Pacific jack mackerel and Atlantic mackerel, silver hake including anchovies. These resources mainly distribute in the Pacific regions, especially FAO statistical fishing areas 67, 77 and 87. It was likely to premature to conclude that the new regime in the sea was only in favour of coastal states in fishey production.

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A Study on the Problem of Application of Seismic Performance Reinforcement Method for Urban Railways Case of Fiber and Rigid Reinforcement (섬유 및 강성 보강재료 기반 도시철도 내진성능 보강공법적용의 문제점 연구)

  • Ha, Kyoung Hwa;Park, Jae Yil;Kang, Hwi Jin
    • Journal of Korean Society of Disaster and Security
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    • v.13 no.1
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    • pp.13-23
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    • 2020
  • In 2005, Urban railway seismic design was introduced in Rep. Of Korea, and many studies on seismic performance evaluation and reinforcement methods were conducted. In accordance with the Enforcement Decree of the Earthquake Disaster Countermeasures Act issued in March 2009, during April 2010 to October 2013, some of local governments established detailed evaluation and reinforcement measures for seismic performance of the urban railway underground structure. Afterwards, the seismic performance reinforcement of the existing urban railway structures was conducted for the sections that a long period of used until the end of 2018, and the reinforcement works are carried out by various methods using the previously studied methods. However, various reinforcing materials and construction methods using have been studied, but the classification research on the construction methods currently applied to reinforcement construction of urban railways is insufficient. The purpose of study is to analysis the cases currently applied to seismic reinforcement construction and to show the characteristics of each construction method, the reasons for its application and problems.

Estimation of Genetic Parameters of Body Weights in Hanwoo Steers(Korean Cattle), Bos Taurus Coreanae Using Random Regression Model (임의회귀모형을 이용한 한우 거세우 체중의 유전모수 추정)

  • Seo, Kang- Seok;Salces, Agapita J.;Yoon, Du- Hak;Lee, Hong- Gu;Kim, Sang- Hoon;Choi, Te- Jeong
    • Journal of Animal Science and Technology
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    • v.50 no.2
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    • pp.151-156
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    • 2008
  • The study aimed to estimate genetic parameters of body weights in Hanwoo steers using random regression model and compare it with single trait animal model. A total of 1,372 Hanwoo steers that belonged to progeny testing program of the Hanwoo Genetic Improvement conducted at the Livestock Improvement Main Center of the National Agricultural Cooperative Federation (LIMC-NACF) in Rep. of Korea were used. Results of the random regression model fitting quadratic function revealed heritability values from 0.17 to 0.30 for the whole testing days up to 800 days. The results of the animal model showed estimated heritability values ranged from 0.24 to 0.36. Estimates of permanent environmental correlations tended to increase with increasing test in days. Unlike in the direct genetic correlation that at early stage the estimate was slightly negative it was 0.30 then increased to approach unity at later stage of test. Comparing the results between random regression model and the animal model showed not much differences and both followed similar pattern and therefore the use of random regression model for the national genetic evaluation of Hanwoo could be implemented.

A Study of the Beauty Commerce Customer Segment Classification and Application based on Machine Learning: Focusing on Untact Service (머신러닝 기반의 뷰티 커머스 고객 세그먼트 분류 및 활용 방안: 언택트 서비스 중심으로)

  • Sang-Hyeak Yoon;Yoon-Jin Choi;So-Hyun Lee;Hee-Woong Kim
    • Information Systems Review
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    • v.22 no.4
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    • pp.75-92
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    • 2020
  • As population and generation structures change, more and more customers tend to avoid facing relation due to the development of information technology and spread of smart phones. This phenomenon consists with efficiency and immediacy, which are the consumption patterns of modern customers who are used to information technology, so offline network-oriented distribution companies actively try to switch their sales and services to untact patterns. Recently, untact services are boosted in various fields, but beauty products are not easy to be recommended through untact services due to many options depending on skin types and conditions. There have been many studies on recommendations and development of recommendation systems in the online beauty field, but most of them are the ones that develop recommendation algorithm using survey or social data. In other words, there were not enough studies that classify segments based on user information such as skin types and product preference. Therefore, this study classifies customer segments using machine learning technique K-prototypesalgorithm based on customer information and search log data of mobile application, which is one of untact services in the beauty field, based on which, untact marketing strategy is suggested. This study expands the scope of the previous literature by classifying customer segments using the machine learning technique. This study is practically meaningful in that it classifies customer segments by reflecting new consumption trend of untact service, and based on this, it suggests a specific plan that can be used in untact services of the beauty field.

A Study on the Refarming Plan of the Low Frequency Bands according to the Transition from Analogue to Digital TV (디지털TV 전환에 따른 저대역 주파수 회수/재배치 방안 연구)

  • Yu, Hyeon-Yong
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.19 no.12
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    • pp.1470-1481
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    • 2008
  • A demand for spectrum resources, especially in the low frequency bands, is ever increasing with the development of mobile telecommunications and so is their economic value as other national resources. Also, development in mobile broadband require more bandwidth with excellent propagation characteristics, such as those frequencies in the 700/800/900 MHz bands. As a way to enhance the economic efficiency of using spectrum resources, many countries including the U.S., the U.K. and Japan, have recently focused on the refarming plan of the low frequency bands according to the transition from analogue to digital TV. By the way, as a result of WRC-07, those parts of the band $698{\sim}960\;MHz$ in Region 2 and the band $790{\sim}960\;MHz$ in Regions 1 and 3 which are allocated to the mobile service on a primary basis are identified for use by administrations wishing to implement International Mobile Telecommunications (IMT). Therefore, after analogue to digital television switchover, some administrations may decide to use all or parts of the band $698{\sim}806/862\;MHz$ for other services to which the band is allocated on a primary basis, in particular the mobile service for the implementation of IMT, while in other countries the broadcasting service will continue to operate in that band. And to conclude, bands already identified for IMT-2000 will also be able to be used for IMT. This work will help establish a policy direction for spectrum refarming in the low frequency bands in Korea(Rep. of).