• Land and Housing Review
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• v.8 no.1
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• pp.23-29
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• 2017

The BIM design is expected to expand to the domestic and overseas construction industries, depending on the effect of construction productivity and quality improvement. However, with the obligation of Public Procurement Service to design the BIM design, it includes a design error and the problem of utilization of 3D design by choosing a simple 2D to 3D remodelling method that can not be modelled in 3D modeling or use of the construction and maintenance phases. The results reviewed by BIM design results were largely underutilized and were not even performed with the verification of the error. In order to resolve this, one must develop the check system that secures the quality of BIM design and ensure that the reliability of BIM results are available. In this study, it is designed to develop a program that can automatically verify the design of the BIM design results such as violation of the rules of the BIM design, design flaws, and improve the usability of the BIM design. In particular, this programs were developed not only to identify programmes that were not commercially available, but also to validate drawings in low-light computer environments. The developed program(LH-BIM) store the information of attribute extracted from the Revit file(ArchiCAD, IFC file included) in the integrated DB. This provides the ability to freely lookup the features and properties of drawings delivered exclusively by the LH-BIM Program without using the Revit tools. By doing so, it was possible to resolve the difficulties of using traditional commercial programs and to ensure that they operate only with traditional PC performance. Further, the results of the various BIM software can be readily validated, which can be solved the conversion process error of IFC in the case of SMC. Additionally, the developed program has the ability to automatically check the error and design criteria of the drawings, as well as the ability to calculate the area estimation. These functions allow businesses to apply simple and easy tasks to operate tasks of BIM modelling. The developed system(LH-BIM) carried out a verification test by reviewing the review of the BIM Design model of the Korea Land & Housing Corporation. It is hoped that the verification system will not only be able to achieve the Quality of BIM design, but also contribute to the expansion of BIM and future construction BIM.

• The Korean Journal of Physiology and Pharmacology
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• v.3 no.4
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• pp.405-414
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• 1999

The role of platelet-activating factor (PAF) was investigated in intestinal ischemia/reperfusion (I/R) induced acute lung injury associated with oxidative stress. To induce acute lung injury following intestinal I/R, superior mesenteric arteries were clamped with bulldog clamp for 60 min prior to the 120 min reperfusion in Sprague-Dawley rats. Acute lung injury by intestinal I/R was confirmed by the measurement of lung leak index and protein content in bronchoalveolar lavage (BAL) fluid. Lung leak and protein content in BAL fluid were increased after intestinal I/R, but decreased by WEB 2086, the PAF receptor antagonist. Furthermore, the pulmonary accumulation of neutrophils was evaluated by the measurement of lung myeloperoxidase (MPO) activity and the number of neutrophils in the BAL fluid. Lung MPO activity and the number of neutrophils were increased (p＜0.001) by intestinal I/R and decreased by WEB 2086 significantly. To confirm the oxidative stress induced by neutrophilic respiratory burst, gamma glutamyl transferase (GGT) activity was measured. Lung GGT activity was significantly elevated after intestinal I/R (p<0.001) but decreased to the control level by WEB 2086. On the basis of these experimental results, phospholipase $A_2\;(PLA_2),$ lysoPAF acetyltransferase activity and PAF contents were measured to verify whether PAF is the causative humoral factor to cause neutrophilic chemotaxis and oxidative stress in the lung following intestinal I/R. Intestinal I/R greatly elevated $PLA_2$ activity in the lung as well as intestine (p<0.001), whereas WEB 2086 decreased $PLA_2$ activity significantly (p<0.001) in both organs. LysoPAF acetyltransferase activity, the PAF remodelling enzyme, in the lung and intestine was increased significantly (p<0.05) also by intestinal I/R. Accordingly, the productions of PAF in the lung and intestine were increased (p<0.001) after intestinal I/R compared with sham rats. The level of PAF in plasma was also increased (p<0.05) following intestinal I/R. In cytochemical electron microscopy, the generation of hydrogen peroxide was increased after intestinal I/R in the lung and intestine, but decreased by treatment of WEB 2086 in the lung as well as intestine. Collectively, these experimental results indicate that PAF is the humoral mediator to cause acute inflammatory lung injury induced by intestinal I/R.

• The korean journal of orthodontics
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• v.37 no.5
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• pp.351-363
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• 2007

The aim of this study was to evaluate pulp and periodontal changes following rapid tooth retraction by periodontal distraction after bone undermining surgery in young adult dogs. Methods: Alter extraction of second premolars, the interseptal bone mesial to the upper 3rd premolar was undermined. After activating the distraction appliance at 0.5 mm/day for six days, the dogs were sacrificed at 0, 1, 3, 5, 7, and 9 weeks during the consolidation period. Tissue changes of periodontium and pulp were evaluated radiologically, histologically, and immunohistochemically. Results: Digital subtraction radiography showed active bone formation in the stretched periodontal ligament from 0 - 4 weeks. Resorption of the alveolar bone, appearance of osteoclasts, and infiltration of inflammatory cells were observed just after the activation period at the pressure side, and distinctive bone formation was seen in the tension side of the periodontal ligament from 1 week. New bone formation was active at 1 - 3 weeks. The expression of calcitonin gene-related peptide in the experimental group was increased at the alveolar bone and pulp, and periodontal ligament at the pressure side from 0 - 1 week, and it decreased after 5 weeks to become similar to that of the control group. Conclusions: The results showed that rapid tooth movement using periodontal distraction can be new form of orthodontic tooth movement for accelerating normal bone formation.

• The korean journal of orthodontics
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• v.30 no.6 s.83
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• pp.723-730
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• 2000

Orthodontic tooth movement requires remodelling of periodontal tissues, especially alveolar bone. Fluoride is known to be a potent inhibitor of osteoclastic bone resorption. The purpose of this study was to examine the effects of a consumption of fluoride on osteoclast numbers appearing on the pressure side of alveolar bones at experimental tooth movement. 40 male rats were exposed to 0, 10, 25 mg/kg/day of sodium fluoride(NaF) in their drinking water for up to 60 days. Orthodontic appliance were activated to mesially tip maxillary first molar with 50-70g. The rats were sacrificed at 1, 2, 4 days after initial activation. The number of osteoclast was counted in a $450\times700\;{\mu}m^2$ area interradicular septum on the pressure side of the maxillary first molar. The results were as fellows, 1. There was significantly different osteoclast number between control group and 25 mg/kg/day group at all measured time. (p<0.05) 2. There was significantly different active bone-resorption area between control group and 25 mg/kg/day group except at 96 hours post activation. (p<0.05) 3. There was slight reduction of active bone- resorption area in control group from 48 hours to 96 hours but in both 10 mg/kg/day group and 25 mg/kg/day group a slight increase was observed from 48 hours to 96 hours.

• The Journal of Internal Korean Medicine
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• v.27 no.2
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• pp.521-532
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• 2006

Backgrounds and Objectives: A major goat in asthma therapy isto reduce or prevent the inflammatory response associated with bronchial hyperresponsiveness, reversible airway obstruction and airway remodelling. Many studies have shown that eosinophilic infiltration is a prominent feathure in the pathophysiology of asthma. The importance of the Presence of eosinophils in the airways of asthmatics has long been recognized, but the mechanism by which these cells are recruited and retained in the lung are only now being elucidated Production of chemotactic cytokines by bronchial epithelial cells may contribute to the local accumulation of eosinophils in Patients with bronchial asthma. This study was designed to investigate the inhibitory effect of extraction of herbal dicoction, Gamichungsangbohatang(GMCSBHT) on eosinophil chemotactic cytokines. Material and Methods:We used water and 70% ethanol extracts of GMCSBHT and pulmonary epithelial cell lines A549(human type II -like epithelial cells). We estimated cytotoxic effects of GMCSBHT, and estimated the effects of water and 70% ethanol extracts of GMCSBHT on chemokines from prestimulated A549 cells by sandwich ELISA. Results: Chemokines of eotaxin, IL-8 were inhibited by GMCSBHT in dose-dependent manner. And ethanol extract of GMCSBHT has more inhibitory effects on eotaxin, IL-8 than hot water extract. Conculusions: These findings indicate that the supression of the expression of chemokines can be accomplished by GMCSBHT treatment, so GMCSBHT may inhibit the iuflammatory process by eosinophils in asthma.

• Journal of the Korean Geotechnical Society
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• v.33 no.12
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• pp.81-92
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• 2017

According to the revision of the Housing Act in 2013, it has been possible to carry out an apartment remodeling project involving two to three floor vertical extension. The remodeling project with vertical extension requires foundation reinforcement because structural safety due to additional load and enhanced seismic criteria must be met. In this case, structural analysis is performed to analyze the load distributed to existing PC pile and reinforced additional pile. The vertical stiffness ($K_v$) of the pile is required for structural analysis, but the research on the 20~30 year old PC pile stiffness is very limited. In this paper, the stiffness of the PC pile in accordance with the change of diameter and length was analyzed by examining the results of 38 field pile load tests performed during the construction of the apartments in the 1990's. As a result of the analysis, the pile stiffness decreases with the increase of the length-diameter ratio (L/D). In addition, the results of on-site pile load test are compared with the coefficient 'a' for estimating pile stiffness proposed in Korea Highway Bridge Design Standard (2008) and the Pile Foundation Design Guideline of Korea Railroad Corporation (2012). It shows that 'a' obtained through the estimation of the literature is very similar to the field test results in the range of 10

• Journal of the Korea Institute of Building Construction
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• v.13 no.2
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• pp.181-192
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• 2013

Given both structural safety and economic benefits of aging facilities, remodelling of the existing facilities is preferable to reconstruction. This recognition provides an opportunity to reduce the commitment of resources and national budget. However, when a subordinate troop asks for remodeling or reconstruction of a deteriorated facility, it is difficult to ensure the consistency and objectivity in the process of decision making for the alternatives due to the absence of systematic and quantitative rating methodology. Their economic evaluation methodology only exists in a manual format. Thus, further research is required for converting the methodology into an automated system in view of practicality such as rapid and accurate data processing. The contributions of this study are as follows: 1) Literature review found out a representative economic evaluation model focused on military facilities, and comparative analysis with a similar study identified the strength and weakness. 2) this study presented how to convert the theoretical framework which enables to solve a specific subject matter into an automated system. 3) it developed a user friendly interfaces which consist of four functional modules by considering the usability and accessibility of the system user. 4) the developed system was verified by a case study in terms of four kinds of performance indicators.

• Journal of the Economic Geographical Society of Korea
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• v.20 no.2
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• pp.245-258
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• 2017

Ministry of Land, Infrastructure and Transport established a comprehensive plan for 83 old industrial complexes over 20-year. They implemented the competitiveness of industrial complex in September 2013, and revitalizing and remodelling comprehensive plan in December 2014. With significant influences of old industrial complex in September 2009, Ministry of Land, Infrastructure and Transport chose the 4 districts for the first pilot project. In December 2014, the second pilot project districts were established. In addition, there were 10 districts in April 2016 and 5 districts in April 2016 as the third pilot project and 5 distiricts in March 2017 as the fourth piolt project. Ministry of Land, Infrastructure and Transport currently suggests 23 districts to regenerate among 83 old industrial complex districts over 20 years. Even though the government suggests the certain 23 districts, this research selects the bottom 23 districts (30%) represented through the Focus Group Interview and compare them with the list government-suggested. As a result, there were some unlisted industrial complex districts. This research suggests the unlisted industrial complex districts which need to be regenerated and their problems, therefore this could be used as a guide for feasibility of old industrial complex regeneration implement.

• Journal of Periodontal and Implant Science
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• v.31 no.3
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• pp.555-564
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• 2001

The purpose of this study is to evaluate the bioresorbability of Calcium Polyphosphate added with $Na_2O$ and chitosan. Though calcium phosphate ceramics meet some of the needs for bone replacement, they have some limitation of unresorbability and fibrous encapsulation without direct bone apposition during bone remodelling. To solve these problem, we developed a new ceramic, calcium polyphosphate(CPP), and report the biologic response to CPP in extraction sites of beagle dog. Porous CPP granules were prepared by condensation of anhydrous $Ca(H_2PO_4)_2$ to form non-crystalline $Ca(PO_3)_2$. CPP granules added with $Na_2O$ and chitosan were implanted in extraction sockets and histologic observation were performed at 12 weeks later. Histologic observation at 12 weeks revealed that CPP matrix were mingled with and directly apposed to new bone without any intervention of fibrous connective tissue. CPP granules added with chitosan were well adatped without any adverse tissue reaction and resorbed slowly and spontaneously. CPP granules added with $Na_2O$ and chitosan show multinucleated giant cells and osteoblast-like cells around grafted material and newly formed bone. This result revealed that CPP, regardless of its additive component, had a high affinity for bone and had been resorbed slowly. From this results, it was suggested that CPP is promising ceramic as a bone substitute and addition of $Na_2O$ and chitosan help biodegradation. In further study , it will be determined which concentration of $Na_2O$ help biodegradation and the other additive components increase the degradation rate.

• Journal of Korea Port Economic Association
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• v.27 no.2
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• pp.313-331
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• 2011

Due to have been more keen in East-North Asia Hub Port competition, to be accelerated Busan New Port development, and to result to supply excess position, Busan port has been confronted by many problems. Also, as facilities of North Port is old, it is impossible to secure 16m depth of water at North Port, and North Port redevelopment is being, container traffic of North Port is accelerated to shift at New Port. Therefore, it. is time to seek for connection growth plan of succeeding together-Busan North & New Port as soon as possible. Connection growth plan of succeeding together-Busan North & New Port is focused, as follows. First, it is required to set up model for connection growth plan of succeeding together-Busan North & New Port. It is valid to specialize for ULCC, to promote to global port at New Port, and it is effective to focus on feeder service and general cargo handling, and to include most space to North Port redevelopment. Second, through port function reorganization, it is required to create a synergy by port function clustering. Third, through effective connection traffic network expansion for moving T/S cargo effectively, it is required to develop Busan Port for T/S cargo-focused port. Fourth, it is required to develop port hinterland logistics zone for creating container traffic through connection development of New Port-BJFEZ. Finally, it is required to build SCM system for creating container traffic among shipper, carrier, freight forwarder and related institution.