• 대한치과교정학회지
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• 제54권1호
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• pp.26-47
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• 2024

Objective: This systematic review aimed to evaluate the correlation between vitamin D levels and the rate of tooth movement, external apical root resorption, bone biomarker expression, and bone remodeling. Methods: Three databases (PubMed, Scopus, and Web of Science) were systematically searched from inception until 14th March 2023 to identify studies investigating the correlation between orthodontic tooth movement and vitamin D in animals and humans. The quality assessment was made in accordance with the Joanna Briggs Institute Critical Appraisal Checklist. Results: Overall, 519 records were identified, and 19 were selected for the qualitative synthesis. Eleven studies investigated the effect of local administration (injections in the periodontal ligament, to the gingiva distal to the teeth, or submucosae palatal area) and systemic administration (oral supplementation) of vitamin D on tooth movement, external apical root movement, pro-inflammatory cytokines, and bone remodeling factors. The remaining eight studies investigated the correlation between serum vitamin D levels and salivary vitamin D levels on bone turnover markers and tooth movement. Conclusions: The findings of this systematic review support that vitamin D3 local injections might increase the rate of tooth movement via the receptor activator of the nuclear factor-kB/osteoprotegerin axis. However, the non-uniform study designs and the different protocols and outcome methods make it challenging to draw reliable conclusions.

• 한국건설관리학회논문집
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• 제15권5호
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• pp.82-93
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• 2014

주거복지 정책 실현을 위해 공급되고 있는 장기공공임대주택은 영구임대주택을 시작으로 급속히 노후화 되고 있다. 이에 노후화 개선을 위해 다양한 주거복지 사업이 추진 및 계획되고 있다. 그러나 모든 주거복지 정책이 다 필요한 것이라고 하더라도 재원은 한정적이기 때문에 재원의 효과적 배분과 투입이 요구된다. 더불어 많은 국가재정 투입이 예상되는 만큼 주거복지를 위한 공공사업에 앞서 사업의 타당성에 관한 검토가 요구된다. 한편, 기존의 타당성 연구는 SOC 사업을 주요 대상으로 한 지침개발이 대부분이기 때문에 본 연구의 대상과 같은 공공 리모델링 사업에 단순한 기존연구 결과의 적용에는 한계가 있다. 더불어 공공사업 타당성 평가를 위해서 경제적 가치와 정책가치 평가가 동시에 이루어져야 하지만 현실적으로 공공사업은 정책결정자의 사업실현 의지와 정책목표의 효과적 달성 등으로 상당부분 사업추진 여부가 결정된다. 이러한 측면에서 본 연구에서는 노후 장기공공임대주택 리모델링과 유지관리 두 대안을 대상으로 정책가치 평가 방법을 제시하고 자였다. 정책가치 평가를 위한 접근방법으로 예비타당성 분석의 정책적 분석 항목의 범주화를 고려하였다. 이를 통해 주거복지를 위한 노후 장기공공임대주택 리모델링 사업의 특성을 고려한 정책가치 평가항목을 도출하고 실증분석 방법으로 유지관리와 리모델링의 정책가치를 MAUT를 이용하여 산출하였다. 실증분석 결과 장기공공임대주택 리모델링 및 유지관리 정책가치 실증분석결과 유지관리의 효용값은 0.2461, 리모델링의 효용값은 0.6161로 리모델링의 정책가치가 큰 것으로 평가되었다. 세부 속성은 유지관리 및 리모델링의 순위가 유사한 것으로 나타났으며 경기부양 효과 극대화, 사업계획과 정책방향의 일치성, 사업의 준비정도 최적화 속성의 순위가 높은 것으로 나타났다. 실증분석 결과를 통해 향후 주거복지 실현을 위해 사업을 추진 시에는 정량적 자료를 근거로 하여 유지관리보다 리모델링의 정책을 실현하는 것이 타당하다는 의사결정을 내릴 수 있다.

• 한국환경보건학회지
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• 제33권2호
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• pp.98-103
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• 2007

This study was performed to measure the changed concentrations of formaldehyde and volatile organic compounds after moving in the newly constructed apartment buildings at Seoul. From December 2004 to October 2005, we measured the concentration of formaldehyde and volatile organic compounds in newly constructed apartment buildings before and after residence. In conclusion, it showed that there was a significant relationship association between the con centration of the volatile organic compound and the formaldehyde and remodeling of the house, built in-furniture, and ventilation of the house. Therefore, it was suggested that we need preventive measures and management plans about various factors such. as remodeling, and built in-furniture, ventilation to decrease the concentrations of volatile organic compounds and formaldehyde.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2002년도 학술논문발표회
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• pp.103-108
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• 2002

The purposes of this research are to use the buildings efficiently and long, save energies, make the cozy and comfortable environment of residential and living spaces, rearrange the related acts for easy implementation of remodelling, and activate the government's support programs so as to make remodelling activated in a safe mode. The scope and methodology of this research include the review of existing literatures and data on remodelling, census on apartment residents, influence factors, and the development of methods for activation of building remodelling and strengthening of safety management, like activation measures, licensing and ordering regulation updates, etc regarding the remodelling. Safety inspection and in-depth inspection before and after remodelling should be regulated. The construction materials for remodelling should be light weighted and the construction methods which can minimize the impact and vibration during construction should be selected. The improvement of regulation on the remodelling contractor qualification and order method should be updated. If the remodelling is activated and safety management is reinforced by the suggested measures, solving of lack of house, prevention of abuse of resources, and improvement of residential environment could be accomplished rationally.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2003년도 학술대회지
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• pp.477-480
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• 2003

기존의 재건축 안전진단의 비용분석은 정량적이지 못한 평가기준과 방법 등 많은 문제점을 가지고 있어 좀더 효율적으로 안전진단 업무를 수행하고, 비용분석 결과의 신뢰성을 향상시키기 위해서는 체계적인 비용분석 절차 및 기준이 필요하다. 따라서 본 연구에서는 각 비용항목들을 정량적으로 도출${\cdot}$산정하고, 효율적으로 비용분석을 수행하기 위한 절차 및 기준을 제시하고자 한다. 재건축 안전진단의 비용분석은 먼저, 내용연수, 실질이자율 등의 기본사항을 결정하고, 구조체 보수${\cdot}$보강비용, 건축 마감 및 설비 성능회복비용, 철거비, 이주비, 유지관리비용 등의 개${\cdot}$보수 비용 및 재건축 비용을 산정하여 이들 비용의 LCC 년가를 비교하여 분석${\cdot}$평가한다.

• Clinical and Experimental Pediatrics
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• 제48권6호
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• pp.580-587
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• 2005

New evidence is emerging that airway smooth muscle(ASM) may act as an immunomodulatory cell by providing pro-inflammatory cytokines and chemokines, polypeptide growth factors, extracellular matrix proteins, cell adhesion receptors and co-stimulatory molecules. ASM can promote the formation of the interstitial extracellular matrix, and potentially contribute to the alterations within the extracellular matrix in asthma. In addition, extracellular matrix components can alter the proliferative, survival, and cytoskeletal synthetic function of ASM cells through integrin-directed signaling. Increased ASM mass is one of the most important features of the airway wall remodeling process in asthma. Three different mechanisms may contribute to the increased ASM mass : cell proliferation, increased migration and decreased rate of apoptosis. The major signaling pathways of cell proliferation activated by ASM mitogens are those dependent on extracellular signal-regulated kinase and phosphoinositide 3'-kinase. The key signaling mechanisms of cell migration have been identified as the p38 mitogen-activated protein kinase and the p21-activated kinase 1 pathways. ASM cells contain ${\beta}2$-adrenergic receptors and glucocorticoid receptors. They may represent a key target for ${\beta}2$-adrenergic receptor agonist/corticosteroid interactions which have antiproliferative activity against a broad spectrum of mitogens.

• Journal of Microbiology and Biotechnology
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• 제28권10호
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• pp.1614-1625
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• 2018

Periodontitis, which is a severe inflammatory disease caused by endotoxins secreted from oral pathogens, destructs gingival tissue and alveolar bone. Curcuma xanthorrhiza, commonly called Java turmeric, has been shown to possess anti-bacterial and anti-inflammatory activities. The present study evaluated the inhibitory effect of C. xanthorrhiza supercritical extract (CXS) standardized with xanthorrhizol on lipopolysaccharide (LPS)-induced periodontitis in an animal model. LPS was topically injected into the periodontium of Sprague-Dawley rats to induce periodontitis and CXS (30 and $100mg{\cdot}kg^{-1}{\cdot}day^{-1}$) was orally administered after day 12. Histologically, CXS inhibited the collapse of gingival tissue by preventing cell infiltration. CXS significantly downregulated the expression of matrix metalloproteases (MMPs) and inflammation-related biomarkers, such as nuclear factor-kappa B ($NF-{\kappa}B$) and interleukin-1 beta ($IL-1{\beta}$) in gingival tissue. CXS also improved bone remodeling by downregulating osteoclastic transcription factors, such as nuclear factor of activated T-cells c1 (NFATc1), tartrate-resistant acid phosphatase (TRAP), and cathepsin K. In addition, CXS upregulated osteoblast differentiation-related markers, alkaline phosphate (ALP) and collagen type I alpha (COLA1). Thus, CXS can ameliorate periodontitis by inhibiting inflammation and improving bone remodeling.

• The Journal of Korean Physical Therapy
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• 제12권3호
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• pp.497-507
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• 2000

This study was performed to understanding on guidelines for using therapeutic modalities according to injury phases of soft tissue. Clinical decisions on how and when therapeutic modalities may be used should be based on recognition of signs and symptoms. as well as some awareness of the time frames associated with the various phases of the Healing process. The physical therapist must have a sound understanding of that process in terms of the sequence of the various process of healing stage. The results of this study are as follows: 1. Once an acute injury has occured, the healing process consists of the imflammatory response phase, the fibroblastic-repair phase, and the maturation-remodeling phase and can impede by various pathologic factors. 2. Modality use in the initial acute injury phase and the inflammatory response phase should be directed toward limiting the amount of swelling and reducing pain. 3. Modality use in the Fibroblastic repair phase may be change from cold to heat. The purpose of heat is to increase circulation to the injured area to promote healing. 4. During the Maturation-Remodeling phase, some type of heating modalities, ultrasound, or short wave and microwave diathermy should be used to increase circulation to the deeper tissue. In this phases, physical therapists must control training and conditioning habits to allow the injury to heal sufficiently.

• 한국태양에너지학회 논문집
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• 제27권4호
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• pp.59-65
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• 2007

This study is to propose the basic data for deciding remodeling of wornout educational facilities. In order of it, the indoor environmental standard, the actual conditions of thermal environment and sound insulation of walls were examined through field measurement in the subjected open elementary school(J school) and modernization model of elementary school(Y school) which they are located in Seoul. As the result, standard for indoor environmental factors of educational facilities which is established by Ministry of Education is not subdivided into indoor environmental performances considering usages and characteristics of classrooms for comfortable indoor environment. The vertical temperature difference in general classroom and in open classroom showed to be $11.2^{\circ}C$ and $12.1^{\circ}C$ respectively, while indoor temperature of special classroon was, on the whole, higher than that of any other classroom due to its specific heat flux of wall materials. The sound insulation performance of the masonry brick wall of classroom satisfied the minimum standard of AIJ, Architectural Institute of Japan, in the open elementary school and the modernization model of elementary school. That is to say, the movable partition wall between the classroom and the corridor disturbed students in their class in the open school.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제49권6호
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• pp.354-359
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• 2023

The temporomandibular joint is a unique structure composed of the joint capsule, articular disc, mandibular condyles, glenoid fossa of the temporal bone, surrounding ligaments, and associated muscles. The condyle is one of the major components of a functional temporomandibular joint. Reconstruction of large mandibular defects involving the condyle is a surgical challenge for oral and maxillofacial surgeons. To restore large mandibular defects, there are different options for free flap method such as fibula, scapula, and iliac crest. Currently, the vascularized fibula free flap is the gold standard for reconstruction of complex mandibular defects involving the condyle. In the present report, neocondyle regeneration after mandible reconstruction including the condyle head with fibula free flap was evaluated. In this report, two patients were evaluated periodically, and remodeling of the distal end of the free fibula was observed in both cases after condylectomy or mandibulectomy. With preservation of the articular disc, trapezoidal shaping of the neocondyle, and elastic guidance of occlusion, neocondyle bone regeneration occured without ankylosis. Preservation of the articular disc and maintenance of proper occlusion are critical factors in regeneration of the neocondyle after mandible reconstruction.