The amount of the radionuclide release to the environment during a LOCA and its radiological consequence are assessed, for a 900MWe French PWR which is similar to the KNU 9/10, according to RFS V.1.a, in which the source term has been revised more conservatively after the TMI accident. The assessed result shows that the whole body and thyroid doses at the site boundary(500m) for 2 hours after the release are 66 mrem and 13.5 rem, respectively, and are within the corresponding limits. It is expected, however, that the thyroid dose would exceed the limit if the fraction of the organic iodine is over 10% of the iodine inventory.
The purpose of this study is to present possibility about applying space design of urban theory focused on collective memory. Urban which is the final data of human's collective life has been recognized creative circumstances human collective is living. It can not think without collective from its motivation to problem of form as well as building as element which compose these cities. It is to recognize essential attribute of construction in the collective that think architecture with urban, and It means that recognize actuality of architecture that can talk as the most collective product that represent human. There was discussion for collective and urban. But, this problem was proceeded to clear human knowledge of architecture mainly in other discipline, and even if speak as field of architecture, it could just pass confined meaning by refering at process that clear several main aspects of architecture as doing not pass over more than it. Problem of form that is ultimate aspect of architecture remained by different thing still doing not combine with collective architecture, and occasionally happened the case that make collective of architecture and relation of form overly incommodiously reducing form by a tool for diagram, shape, figuration in the aspect of collective. This research study concept for memory collective in the urban and collective of architecture, and choose urban planning methodology and their work by specific example between Aldo Rosi and Rem Koolhaas dealing with architecture and urban, and present possibility about space design of urban.
The purposes of this study were to compare Louis I. Kahn and Rem Koolhaas, both of whom established their architectural theories and granted rationality to them by applying the theory of psychoanalysis, and examine common and different characteristics in the inner space composition of a building between them. The study also set out to confirm a basic premise based on which to develop a metaphysical design concept by applying the theory of psychoanalysis in the inner space composition of contemporary architecture in future from the more developed and integrated perspective of modern psychoanalysis. As a result, Kahn sought after a metaphysical design concept through the combinations of inner unit spaces including servant and served space, which are comparable to the confrontation between consciousness and unconsciousness from the perspective of psychoanalysis. Unlike him, Koolhaas applied the concept of folding to his architectural plans based on the theory of post-structuralism and created a metaphysical design concept by more focusing on connections between unit spaces rather than their combinations. While Kahn worked on his designs with much interest in the combinations of inner unit spaces in horizontal circulation by separating it from vertical circulation, Koolhaas created a new design concept beyond the limitations of Kahn, who had a confronting, dichotomous view of the world between the phenomenal world and the metaphysical world, by making use of inclined slabs to connect upper slabs with lower ones. The findings show that there can be various metaphysical design concepts depending on how to connect and combine two confronting concepts when applying the theory of psychoanalysis to architectural design.
The purpose of this study is to prove the effect of psychic distance between home country and host country on overseas foreign direct investment(OFDI) of Spanish companies through panel analysis. The panel data was based on cultural, institutional, economic, and geographical distance data over the past decade between Spain and Spain's OFDI countries. According to the Random Effect Model(REM) analysis, cultural distance(CULD) had a negative effect on OFDI, while institutional distance(INSD) had a positive effect. Among economic distances, income size distance(GDP) had a positive effect on OFDI, but export size distance(EXPO) had a negative effect. Geographic distance(PKM) had a negative impact. Meanwhile, according to the results of quantile regression analysis to prove the psychic distance effect by OFDI size, the effects of CULD and INSD in the quartile (75%) to which Korea belongs were the same as the REM analysis results. In addition, GDP and EXPO had a positive effect, and PKM had a negative effect but EXPO had a positive effect. Therefore, FDI host countries need to establish differentiated strategies through quantile analysis while making continuous efforts to improve the system.
Park, Min-Woo;Cho, Jung-Hwan;Park, Won-Kyu;Nam, Jin-Woo;Yun, Chong-Il;Chung, Jin-Woo
Journal of Oral Medicine and Pain
/
v.34
no.4
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pp.371-377
/
2009
Objectives: The aim of this study was to evaluate the differences in the polysomnography data between positional and non-positional obstructive sleep apnea (OSA) patients. Methods: Forty-seven patients diagnosed with OSA were evaluated using full night polysomnography. According to the criteria of Cartwright et al., the patients were classified into two groups with 37 positional (supine apnea-hypopnea index [AHI] $\geq$ 2x's the lateral AHI) and 10 non-positional (supine AHI < 2x's the lateral AHI) OSA patients, and the differences of polysomnography data between the two groups were evaluated. Results: There were no significant differences in demographic variables (age, gender, and BMI), daytime sleepiness, overall AHI, total arousal index, and percent time of snoring between two groups. However, AHI, arousal index, and mean oxygen saturation ($SpO_2$) of the REM sleep stage were significantly more severe in the positional OSA group than the non-positional OSA group. Mean $SpO_2$ and the lowest $SpO_2$ during overall sleep stage were also significantly lower in the positional OSA group than the non-positional OSA group. Conclusions: Our results of differences in the polysomnography data of REM sleep stage suggest that non-positional OSA patients may have higher collapsibility of the oropharyngeal airway during sleep than positional OSA patients.
The aim of this study was to determine the statistical significance of heart rate variability(HRV) between sleep stages, Apnea-hypopnea index(AHI) and age in patients with obstructive sleep apnea(OSA). This study evaluated the main parameters of HRV over time domain and frequency domain in 40 patients with sleep apnea. The non-REM(sleep stage) was statistically validated by comparing the AHI degree of the three groups(mild, moderate, severe) of sleep apnea patients. The NN50(p=0.043), pNN50(p=0.044), VLF peak(p=0.022), LF/HF(p=0.028) were statistically significant in the R-R interval of patients with sleep apnea from the control group (p<0.05). The LF / HF (p = 0.045) and HF power (p = 0.0395) parameters between the non-RAM sleep (sleep 2 phase) and REM sleep in patients with sleep apnea were statistically significant in the control group(p<0.05). We may be able to provide a basis for understanding the correlation among AHI, sleep stage and age and heart rate variability in patients with obstructive sleep apnea.
A taste-testing method that accurately measures consumer-acceptance is critical during the course of the product development stage. Although various types of consumer-acceptance tests are available, the testing protocol appropriate for measuring the acceptance of ready-to-eat-meals (REM) has not yet been verified. In this study, various hedonic taste-testing methods (9-point hedonic scaling, best-worst scaling, open ended response) were compared for their efficiency and power in identifying the preferred REM menu of consumers. Forty-four consumers evaluated the acceptance of five types of REM menu samples consisting of a wide variety of flavors. Consumers initially used the 9-point hedonic rating method to choose the best and the worst sample among the 5 meals tested. Finally, consumers were asked to fill out open-ended comments where they could freely describe their liking and disliking of each sample. The results showed that the REM menu acceptance measured by the 9-point hedonic method that rated best-worst scaling exhibited a similar preference pattern. The open-ended response method could not provide a quantifiable acceptance data but was able to provide supplementary information regarding the limitations of the samples and therefore, provide a general idea of the direction of improvement during the product development.
Narcolepsy is characterized by sleep attack with excessive daytime sleepiness(EDS), cataplexy, sleep paralysis, and hypnagogic hallucination. Paradoxically, narcoleptics tend to complain of frequent arousals and shallow sleep during the night time despite their excessive sleepiness. However, nocturnal sleep fragmentation in narcoleptics is relatively ignored in treatment strategies, compared with sleep attack/EDS and cataplexy. In our paper, we attempted to investigate further on the poor nocturnal sleep in narcoleptics and to discuss possible treatment interventions. Out of consecutively seen patients at Seoul National University Sleep Disorders Clinic and Division of Sleep Studies, we recruited 57 patients, clinically assessed as having sleep attack and/or EDS. Nocturnal polysomnography and multiple sleep latency test(MSLT) were done in each of the subjects. We selected 19 subjects finally diagnosed as narcolepsy(mean age $26.0{\pm}18.3$ years, 16 men and 3 women) for this study, depending on the nocturnal polysomnographic and MSLT findings as well as clinical history and symptomatology. Any subject co-morbid with other hypersomnic sleep disorders such as sleep apnea or periodic limb movements during sleep was excluded. Sleep staging was done using Rechtschaffen and Kales criteria. Sleep parameters were calculated using PSDENT program(Stanford Sleep Clinic, version 1.2) and were compared with the age-matched normal values provided in the program. In narcoleptics, compared with the normal controls, total wake time was found to be significantly increased with significantly decreased sleep efficiency(p<.01, p<.05, respectively), despite no difference of sleep period time and total sleep time between the two groups. Stage 2 sleep%(p<.05), slow wave sleep%(p<.05), and REM sleep%(p<.01) were found to be significantly decreased in narcoleptics compared with normal controls, accompanied by the significant increase of stage 1 sleep%(p<.01). Age showed negative correlation with slow wave sleep%(p<.05). The findings in the present study indicate significant fragmentation of nocturnal sleep in narcoleptics. Reduction of REM sleep% and the total number of REM sleep periods suggests the disturbance of nocturnal REM sleep distribution in narcoleptics. No significant correlations between nocturnal polysomnographic and MSLT variables in narcoleptics suggest that nocturnal sleep disturbance in narcoleptics may be dealt with, in itself, in diagnosing and managing narcolepsy. With the objective demonstration of qualitative and quantitative characteristics of nocturnal and daytime sleep in narcoleptics, we suggest that more attention be paid to the nocturnal sleep fragmentation in narcoleptics and that appropriate treatment interventions such as active drug therapy and/or circadian rhythm-oriented sleep hygiene education be applied as needed.
Kim, Ju-Sang;Kim, Sung-Kyung;Lee, Sang-Haak;Ahn, Joong-Hyun;Kim, Chi-Hong;Moon, Hwa-Sik
Sleep Medicine and Psychophysiology
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v.14
no.1
/
pp.49-53
/
2007
Mitochondrial myopathy is characterized by variable clinical manifestations from mild limb weakness to fatal respiratory failure and central nervous system sequela. But it is a rare event that sleep disordered breathing become a clue of diagnosis for mitochondrial myopathy. We report a case of a 21 year-old man who was diagnosed as mitochondrial myopathy during the investigation for the possible cause of chronic hypoventilation syndrome. Before being admitted to our hospital, he was suspected as having sleep apnea syndrome in another hospital. We re-evaluated the history, physical examination, laboratoy findings and polysomnography in detail. Severe hypoxemia was noted during REM sleep on nocturnal polysomnography and the diagnosis of mitochondrial myopathy was made by muscle biopsy in rectus abdominis muscle. We treated him with bilevel positive airway pressure therapy during sleep and it could reverse the hypoxemia during REM sleep. He could be discharged with improved condition and is being well with the use of this ventilatory assistance.
Kim, Jin-Hang;Hong, Seung-Bong;Yi, Ji-Yeong;Cho, Keun-Chong
Sleep Medicine and Psychophysiology
/
v.6
no.2
/
pp.116-125
/
1999
Objectives: The purpose of this study is to investigate the effect of exercise load on sleep structure and stress hormone secretion during sleep. Methods: Five male physical education students were included in this study after giving their written, informed consents in the Research Institute for Sports Science at the University of Hanyang. All subjects have performed for at least 3 years in a regular aerobic exercises such as football, basketball, and running. The subjects were divided into three groups ; NOE(non-exercise), MDE(middle duration exercise), LDE(long duration excercise). MDE group maintained a total of 120 min exercise, and LDE group maintained a total of 300 min exercise by football, basketball or badminton. All subjects were acclimatized to the experimental sleep condition by spending one night under expermental conditions, including the placement of an intravenous catheter. During the subsequent night(24:00-08:00), somnopolygraphic sleep recordings were obtained, and blood for measuring growth hormone, cortisol, testosterone, and $\beta$-endorphin was collected every 120 min throughout the night. Blood samples were obtained from prominent forearm veins of subjects. Then, the samples were immediately placed in ice and centrifuged within 10 min at 3000 rpm at $4^{\circ}C$. Statistical analyses were performed using the SPSS/$PC^+$. Data were analyzed by one-way ANOVA with repeated measures. Results: No significant differences among groups were observed in sleep latency, total sleep time, stage 2 sleep, and slow wave sleep. However, daytime exercise produced significant changes in stage 1 sleep, REM sleep, stage 2 sleep latency, REM sleep latency and sleep efficiency. Stage 1 sleep, stage 2 sleep latency, and REM sleep latency significantly increased in LDE compared to those of NOE and MDE groups. But the amount of REM sleep significantly decreased in LDE. Sleep efficiency of MDE was higher than those of NOE and LDE. The blood concentrations of growth hormone, testosterone, and cortisol during night sleep were significantly lower in LDE than in NOE. $\beta$-endorphin concentrations in blood during night sleep were not different among groups. Conclusion: The daytime exercise load was significantly related to sleep structure and stress hormone secretion during night sleep. Long duration exercise showed a harmful effect on sleep structure and hormone secretion. However, middle duration exercise had a beneficial effect on sleep structure and hormone secretion during sleep.
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