• 한방재활의학과학회지
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• 제19권3호
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• pp.123-134
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• 2009

Objectives : We supposed that abdominal muscles are related to chronic cough, because abdominal pressure and respiratory muscles are influenced by abdominal muscle function. We have evaluated the effect of myofacial releasing of abdominal muscles with oriental medical treatment by experimenting two patients suffering from chronic cough. Methods : One patient was treated with acupuncture therapy and muscle stretching exercise for myofacial releasing of abdominal muscle. The other patient was treated with hot pack therapy and abdominal respiration training for myofacial releasing of abdominal muscle. Results and Conclusions : After oriental medical treatment of abdominal muscles in two cases, We figured out that the patients were on the mend. These results suggest that myofacial releasing of abdominal muscles using oriental medical treatment was effective in improving chronic cough.

• 한국추진공학회지
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• 제16권3호
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• pp.24-33
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• 2012

본 연구에서는 풀림방지 볼트를 설계하는 방법을 제시하고 화약 작동 후 볼트 몸체의 특성 변화에 대한 자료를 제공한다. 이와 같은 연구 결과를 증명하기 위하여 M10, M20의 모델을 제작하였고, 폭발 볼트 몸체의 특성 변화에 대한 자료는 시험적으로 획득하였다. 이를 통하여 본 연구는 볼트 몸체의 팽창은 재연성이 있으며 팽창율은 설계인자의 조합에 의해 제어될 수 있다는 것과 풀림방지 특성은 수치화 될 수 있다는 것을 입증했다. 본 연구는 또한 풀림방지 성능을 갖는 볼트를 제작하는데 필요한 자료들을 제공하고 있다.

• 한방재활의학과학회지
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• 제18권2호
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• pp.111-118
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• 2008

Objectives : Plantar fasciitis is most common cause of heel pain which starts from anterior tubercle of calcaneus. It is chronic inflamation of plantar fascia, reduces collagen and water content of heel pad which incur the degenerative changes with elastic fiber weakness. We have evaluated the effect of myofacial releasing therapy and acupuncture therapy by experimenting two patients suffering from plantar fasciitis. Methods : Two patients were diagnosed as plantar fasciitis through their symptoms. We used myofacial releasing therapy and acupuncture therapy to the patients and measured VAS(Visual analogue scale). Results and Conclusions : After treating myofacial releasing therapy and acupuncture therapy in two cases, We figured out that the patients were on the mend. These results suggest that myofacial releasing therapy and acupuncture therapy were effective to heel pain.

• Clinical and Experimental Reproductive Medicine
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• 제48권1호
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• pp.11-26
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• 2021

Advances in anticancer treatments have resulted in increasing survival rates among cancer patients. Accordingly, the quality of life after treatment, particularly the preservation of fertility, has gradually emerged as an essential consideration. Cryopreservation of embryos or unfertilized oocytes has been considered as the standard method of fertility preservation among young women facing gonadotoxic chemotherapy. Other methods, including ovarian suppression and ovarian tissue cryopreservation, have been considered experimental. Recent large-scale randomized controlled trials have demonstrated that temporary ovarian suppression using gonadotropin-releasing hormone agonists (GnRHa) during chemotherapy is beneficial for preventing chemotherapy-induced premature ovarian insufficiency in breast cancer patients. It should also be emphasized that GnRHa use during chemotherapy does not replace established fertility preservation methods. All young women facing gonadotoxic chemotherapy should be counseled about and offered various options for fertility preservation, including both GnRHa use and cryopreservation of embryos, oocytes, and/or ovarian tissue.

• 한방비만학회지
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• 제23권1호
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• pp.18-27
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• 2023

Objectives: The purpose of this study was to review the studies of musculotendinous releasing manual therapy and suggestions for clinical application. Methods: Derive research questions using the scoping review methodology. Searching for related studies, the studies were selected, and the data were analyzed and reported. We searched domestic database for studies on musculotendinous releasing manual therapy reported till April 2023. We reviewed 82 studies excluding duplicate studies and 13 studies were selected. Results: Five studies were literature studies and eight studies were clinical studies. Among the five literature studies, two studies investigating and analyzing general manual therapy, one study investigating manual therapy applied to frozen shoulders, and one systematic literature review to investigate the economic effects of manual therapy, one study using tools. There was one study examining research trends in manual therapy. Eight clinical studies were conducted on patients with Achilles tendinitis, tennis elbow, meralgia paresthetica and obesity. Conclusions: Musculotendinous releasing manual therapy is thought to be applicable not only to musculoskeletal disease but also to changes in body shape due to connective tissue.

• 한국해양생명과학회지
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• 제7권1호
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• pp.29-36
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• 2022

돌기해삼 Apostichopus japonicus는 주요 양식 대상 무척추동물로서 우리나라 연안 해역에 서식하고 있다. 본 연구는 방류 방법에 따른 단기간의 생리학적 스트레스 정도를 평가하기 위하여 heat shock protein 90 (HSP90) 유전자의 발현 변화를 실시간 정량적 중합효소연쇄반응법으로 조사하였다. 어린 돌기해삼을 비닐봉지에 산소 포장하여 30분간 수송하거나 방류 해역의 간조기에 1시간 공기 중에 노출된 실험군의 HSP90 유전자 발현은 대조군의 HSP90 유전자 발현에 비하여 통계학적으로 유의미하게 증가하였다(수송 후 실험군 p=0.001; 간조기 실험군 p=0.032). 어린 돌기해삼을 방류 후 6시간까지 분석한 결과, 선상에서 씨뿌림 방식으로 방류된 6시간째의 개체 및 호스를 통과하여 수중으로 방류된 2~6시간째의 HSP90 유전자 발현율은 대조군에 비하여 약간 감소하는 경향을 보였다(씨뿌림 실험군 p=0.069; 호스 방류군 p=0.093). 한편, 잠수부에 의해 수중에서 방류된 어린 돌기해삼은 방류 후 시간이 경과할수록 HSP90 유전자 발현율은 증가하는 패턴이 관찰되었다(p=0.061). 이상의 결과는 방류된 어린 돌기해삼의 단기간 스트레스 반응 연구와 효과적인 방류 방법의 개발에 HSP90 유전자 발현이 유용하게 사용될 수 있음을 시사한다.

• 경영과학
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• 제29권3호
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• pp.157-168
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• 2012

In this study, we consider an order promising problem at parallel machine shops where orders arrive dynamically. We develop methods for the problem, which instantly quote the due-dates of arrived orders. In this study, we first propose methods which can estimate flow times of orders, in which the current and future inventory status as well as the specific scheduling scheme used in the shop are taken into account, and then the due-dates are set by the order promising methods using the estimation results. The quoted due-dates of orders are compared with the actual completion times of those which are obtained from the simulation runs. The series of computational experiments show that the superior performance of the proposed methods in terms of the accuracy of due-date quotation.

• Journal of Pharmaceutical Investigation
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• 제30권2호
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• pp.85-91
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• 2000

We have studied the dissolution kinetics of two fast releasing tablets in four media, and the similarity of dissolution profiles was compared using 3 methods. Two of the methods were introduced from statistical algorithm of distance methods, which are maximum distance and Mahalanobis distance. The dissolution kinetics were also analysed using FDA method for similarity evaluation, and the results were compared with those obtained using the distance methods.

• 한국환경과학회지
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• 제27권9호
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• pp.763-770
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• 2018

Bioremediation in situ is heavily dependent on the oxygenic environment which would privide the dwelling microorganism with sufficient oxygen. The situation could be easily resolved with supply of an Oxygen Releasing Compound (ORC). In this paper we prepared that sort of material out of oyster shell powder (mostly calcium carbonate) that prevails every shore areas of the country. We used two different oxidizing methods in the first step of the whole manufacturing process-conventional heating in a furnace and an ultrasound generator to obtain calcium oxide. Then that calcium oxide was further oxidized into calcium peroxide which may release oxygen under a moisturized condition. The oxygen releasing experiments were run to test the performance of our products, and to determine the gas kinetics during the experiments. Interestingly, calcium peroxide derived from ultrasound treatment was much more energy-effective as ORC than that from furnace heating although the heat derived process was better than that of ultrasound in terms of oxygen content and its releasing rate. We also found that most of the data collected from the gas releasing experiments fairly supported an ordinary $1^{st}$ order kinetics to oxygen concentration, which shaped a sharp discharge of oxygen at the very early moment of each test.

• IMMUNE NETWORK
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• 제4권4호
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• pp.244-249
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• 2004

Background: Corticotropin-Releasing Hormone (CRH), an important regulator of stress response, has a potent immunoregulatory effect with the ability to promote the growth of various cancer through CRH receptor type 1 under stress. Although the metastasized cancers through cell migration are more aggressive than the primary cancers, little is known about the effect of CRH on cell migration. Gastric cancer is prone to metastasize to other tissues and it is reported that gastric cancer is response to various stresses such as oxidative stress. Herein, we studied the relationship between CRH and gastric cancer cell migration. Methods: We used gastric cancer cell line, MKN-28 and tested the CRH receptor type 1 expression on MKN-28 by RT-PCR. To examine the change in the ability of migration by CRH in MKN-28, cells were incubated with CRH and then migration ability was measured using a cell migration assay. Results: We confirmed that CRH receptor type 1 was expressed in MKN-28 and HaCaT cells. The migration ability of MKN-28 cells was increased by CRH in a time-, dose- dependent manner. Conclusion: These data suggest that CRH increases migration ability in gastric cancer cell line and that CRH may be a critical regulator in the metastasis of gastric cancer cell.