• 한국환경보건학회지
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• 제32권3호
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• pp.235-239
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• 2006

Cichorium intybus (Compositae) has been used for fevers, dyspepsia, headache and jaundice, as a demulcent. Also, it has relaxation effects and relief effects against coffee and teas, and is widely used as food. We investigated anti-lipid peroxidative effects and liver protective activity on $CCl_4$ induced lipid peroxidation and hepatotoxicity in rats. MeOH Ex. enhanced the inhibition of anti-lipid peroxidative effects in liver lipid. In chemical parameters obtained from serum analysis, MeOH Ex. revealed significant decrease on hepatotoxicity. The results were as follows; 1. The inhibitory effects of lipid peroxidation were shown in accordance with the increase of samples' concentration level. 2. In chemical parameters obtained from serum analysis, the activities of GOT, GPT, AlP were restored to near the normal level. The contents of cholesterol and BUN showed inhibitory effects with valence. 3. The weights of liver and spleen were not able to restore to the normal level. But on a general level, they were reduced more than the control group.

• 셀메드
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• 제6권3호
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• pp.18.1-18.4
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• 2016

Patients often suffer from continuous pain negatively affecting their daily life despite a surgical operation. Various studies on complementary therapies against pain have been accumulated as patient with pain desires the improvement in quality of life. Massage therapy as a complementary therapy has been applied widely to decrease the pain and promote relaxation. Thermotherapy with massage is also useful for the treatment of musculoskeletal disorders. Here, the author reports that VOSKIN 125+^®, a new massage instrument, was designed directly to be adjusted from 38-50 degrees Celsius depending on the individual symptoms by lifting the skin and muscles with a negative compression in illness area for alleviating all pain. It transfers pressure and heat to area of illness and eases the pain. In addition, it has significant anti-inflammatory effects and promotes metabolism activity. VOSKIN 125+^® can be therapeutic for pain of musculoskeletal patients. Therefore, I suggest that VOSKIN 125+^® can be useful for a great number of patients suffering from persisting pain.

• 한국관광식음료학회지:관광식음료경영연구
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• 제7권
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• pp.207-230
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• 1997

Over the past few years, the economic growth had a great effect on tourism. As a number of tourist increase, particulary in the relaxation tourism, tourists inevitably need some measures which health their liver, as a social value. In this respect, it is required efficient development of hot springs designed to contribute to the improvement of national health, and suggest some good directions through on analysis of the following 1. The method of developping connection the neighborhood tourism area. 2. The development of travel commodities for trying to attract tourists, connecting hot spring bath. 3. The activity for management. 4. The establishment for tourism action. 5. The setting up development planning 6. The creation of attractive street.

• 대한의용생체공학회:의공학회지
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• 제10권2호
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• pp.109-111
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• 1989

An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients.

• The Korean Journal of Physiology and Pharmacology
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• 제17권1호
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• pp.31-36
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• 2013

The present study was undertaken to investigate the influence of eupatilin on vascular smooth muscle contractility and to determine the mechanism involved. Denuded aortic rings from male rats were used and isometric contractions were recorded and combined with molecular experiments. Eupatilin more significantly relaxed fluoride-induced vascular contraction than thromboxane $A_2$ or phorbol ester-induced contraction suggesting as a possible anti-hypertensive on the agonist-induced vascular contraction regardless of endothelial nitric oxide synthesis. Furthermore, eupatilin significantly inhibited fluoride-induced increases in pMYPT1 levels. On the other hand, it didn't significantly inhibit phorbol ester-induced increases in pERK1/2 levels suggesting the mechanism involving the primarily inhibition of Rho-kinase activity and the subsequent phosphorylation of MYPT1. This study provides evidence regarding the mechanism underlying the relaxation effect of eupatilin on agonist-induced vascular contraction regardless of endothelial function.

• The Korean Journal of Pain
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• 제22권1호
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• pp.78-82
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• 2009

Obturator nerve block has been used for analgesia of hip pain, relaxation of adductor muscle spasm related to cerebral palsy or paraplegia and in urologic surgery to prevent inadvertent obturator activity during lateral wall cystoscopy. Recently, ultrasound guidance has gained popularity in the field of peripheral nerve block and have been reported in some benefits. We describe here successfully performed both obturator nerve block under ultrasound guidance.

• The Korean Journal of Ceramics
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• 제3권1호
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• pp.37-42
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• 1997

The DC current variation of calcia doped zirconia single crystal was measured under various oxygen containing gases at high temperatures. The DC current was influenced by the gas species for oxygen activity establishment. Also, strong non-ohmic characteristics were observed in the $CO/CO_2/N_2$ gas mixtures. Based on the experimental data obtained by introducing the non-buffering gas $N_2$ into the $CO/CO_2$ mixtures, the processes occurring at the gas/solid interface during a defect relaxation process are discussed.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 2001년도 학술 발표회 진행표 및 논문초록
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• pp.67-67
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• 2001

Our previous studies showed that the relaxation defect of diabetic heart was due to the changes in the expressional levels of SR $Ca^{2＋}$-ATPase and PLB. In the diabetic heart contractile abnormalities were also observed, and one of the mechanisms for these changes could include alterations in the expression and/or activity levels of various $Ca^{2＋}$ regulatory proteins involving cardiac contraction.(omitted)

• 대한정형외과스포츠의학회지
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• 제3권2호
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• pp.118-127
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• 2004

The foot and ankle are one of the most common sites for acute musculoskeletal injuries related to sports activity. Foot and ankle injury includes ligament injury, tendon injury, bone and osteochondral injury, nerve injuy, heel pain syndrome, phalangeal injury. This is a article about nonoperative management of foot and ankle injury. Therefore, this article includes various exercise technique, range of motion, stretching for muscle relaxation, proprioception training for rehabilitation. We recommend that orthopedic surgeon should discuss with patient and specialist for treatment plan after foot and ankle injury

• Biomolecules & Therapeutics
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• 제9권2호
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• pp.119-124
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• 2001

In order to determine the role of dehydroepiandrosterone (DHEA), the important sex-steroid hormone precursor, in vascular reactivity in rats, animals were treated for two weeks with DHEA or sex hormones, and the vascorelaxant and contractile responses of isolated aorta were examined. DHEA diminished the acetylcholine (ACh)-induced relaxation in female rats, while the drug was without effect in males. Testoterone lowered the vasorelaxant activity to ACh in either sex. 17$\beta$-Estradiol enhanced ACh-induced vasorelaxation in male rats, but this female sex hormone did not influence in females. In male rats, the androgen receptor antagonist flutamide also enhanced vasorelaxant action of ACh. When the male rat aorta was incubated in vitro with a nitric oxide (NO) synthase inhibitor L-NAME, phenylephrine-induced contraction was greatly potentiated in DHEA-pretreated rats compared to control ones. The present results suggest that DHEA stimulates mainly androgen in female, but both androgen and estrogen in male rats. The participation of NO In the modulation of vascular reactivity with pretreated DHEA was also considered.