• Journal of Gastric Cancer
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• 제21권3호
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• pp.268-278
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• 2021

Purpose: While several prognostic models for the stratification of death risk have been developed for patients with advanced gastric cancer receiving first-line chemotherapy, they have seldom been tested in the Chinese population. This study investigated the performance of these models and identified the optimal tools for Chinese patients. Materials and Methods: Patients diagnosed with metastatic or recurrent gastric adenocarcinoma who received first-line chemotherapy were eligible for inclusion in the validation cohort. Their clinical data and survival outcomes were retrieved and documented. Time-dependent receiver operating characteristic (ROC) and calibration curves were used to evaluate the predictive ability of the models. Kaplan-Meier curves were plotted for patients in different risk groups divided by 7 published stratification tools. Log-rank tests with pairwise comparisons were used to compare survival differences. Results: The analysis included a total of 346 patients with metastatic or recurrent disease. The median overall survival time was 11.9 months. The patients were different into different risk groups according to the prognostic stratification models, which showed variability in distinguishing mortality risk in these patients. The model proposed by Kim et al. showed relative higher predicting abilities compared to the other models, with the highest χ² (25.8) value in log-rank tests across subgroups, and areas under the curve values at 6, 12, and 24 months of 0.65 (95% confidence interval [CI]: 0.59-0.72), 0.60 (0.54-0.65), and 0.63 (0.56-0.69), respectively. Conclusions: Among existing prognostic tools, the models constructed by Kim et al., which incorporated performance status score, neutrophil-to-lymphocyte ratio, alkaline phosphatase, albumin, and tumor differentiation, were more effective in stratifying Chinese patients with gastric cancer receiving first-line chemotherapy.

• 한국항만경제학회지
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• 제21권4호
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• pp.239-253
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• 2005

Although logistics service quality is considered an essential strategy for success and survival in today's internet environment, there are still a lot of question: what variables determine the extent of logistics service effect, how difficultly do the determinants affecting logistics service effect and how accomplish the decision making in the implementation of inter-organization information system. The purpose of this study is to examine a model to utilize the application and effect of logistics service through e-marketplaces. The results of empirical analysis are mentioned as follows; First, among the interorganization information system factors, four variables(top management support in organization characters, competitive degree in environment characters, relative advantage and information efficiency in innovation characters) have been shown to be primary determinant of the effect of logistics service quality. Second, the type of independent variable used results in a significant difference in the effect of logistics service quality. Third, Korean firms have to pursue the corporate strategy focused on logistics service quality.

• 품질경영학회지
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• 제22권4호
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• pp.59-78
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• 1994

In some observational studies, we have often random censoring model. However, the data available may be partially observable censored data consisting of the observed failure times and only those nonfailure times which are subject to follow up. In this paper, we present an extension of the problem of partially parametric estimation of the survival function to such partially observable censored data. The proposed estimator treats the observed failure times nonparametrically and uses a parametric model only for those nonfailure times which are subject to follow-up. We discuss the motivation and construction of the proposed estimator and investigate the limiting properties of the proposed estimator such as asymptotic normality. Also, when the assumed parametric model is exponential, the asymptotic variance of the estimator is obtained. Furthermore, an example is given to compare the proposed estimator with the modified Kaplan Meier(MKM) estimator. From the results, it is shown that the relative efficiency of the proposed estimator is higher than that of the MKM estimator in the follow-up study with increasing time.

• Asian-Australasian Journal of Animal Sciences
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• 제15권9호
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• pp.1354-1358
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• 2002

Two hundred and ten post-larvae (PL) of Macrobrachium rosenbergii (14.5-14.9 mg) were equally distributed in two experimental groups and fed with either steam cooked or extruded pellet for a period of 60 days. Physical evaluation and growth promoting effect of both the pellets were assessed. Significantly higher (p<0.05) water stability, absorption and protein efficiency ratio (PER) were recorded in extruded pellet than the steam cooked pellet. Nutrient loss was minimum in the extruded pellet for which lower feed conversion ratio (FCR) (p<0.05) was recorded in this group. However, weight gain, relative growth and specific growth rate (SGR) in both the groups were not significantly different (p>0.05). Although insignificant (p>0.05) but higher amylase activity was recorded in steam pellet fed group. Survival was not affected by feeding either of the diets.

• Asian-Australasian Journal of Animal Sciences
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• 제9권2호
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• pp.195-197
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• 1996

Peking duck embryos incubated for 82 hrs after oviposition, stage 18 to 20(Hamberger and Hamilton, 1951) were transferred into the recipient eggshells and further incubated at $38.0^{\circ}C$ RH(relative humidity) 60 to 70%, with rotation at an angle of $30^{\circ}$ and the frequency of 4 times an hour. The survival rate was 100, 98, 82, 82, 70, 46, 21 and 16%, after the incubation period of 4, 8, 12, 16, 20, 24, 28 and 29 days, respectively. The present result clearly shows that the ex ova culture is possible for the Peking duck just as in the cases of the chicken or the quail. This culture technique could be useful for experimental manipulation of the embryos.

• Journal of Chest Surgery
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• 제28권12호
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• pp.1155-1159
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• 1995

Differentiated thyroid carcinoma is a slow growing tumor with relative good prognosis. But locally advanced thyroid cancer with T4 or N1b is difficult to manage. Between June 1988 and April 1995, we resected 8 advanced thyroid cancers trans-sternally. All patients had direct mediastinal extension [T4 or mediastinal lymph node metastasis [N1b with airway obstruction or dysphagia. We operated all the patients by partial or total sternotomy for mediastinal dissection along with thyroidectomy and radical neck dissection. There were some acceptable morbidities but no operative mortality. Postoperative radioactive iodine therapy was followed without side effects. Follow-up survival period was between 11 months to 81 months with 2 late mortalities [17 month, 30 month . Although definite benefit for routine mediastinal dissection in thyroid cancer has not been established, in locally advanced cases impending airway obstruction or dysphagia who have questionable effect by radioactive iodine therapy alone, aggressive mediastinal mass dissection including lymph node metastasis has the significant role to prevent the patients from suffocation & dysphagia, and to enhance the effect of followed radioactive iodine tharapy.

• 한국유기농업학회지
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• 제9권4호
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• pp.53-69
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• 2001

The word \"permaculture\" is a contraction of \"permanent agriculture\" or \"permanent culture\". Permaculture principles are designed to support (or ensure) the survival of humanity, the earth and all on it, and, to improve our standard of living, Permaculture can be defined as : a design system for creating sustainable human environments that can be (relatively) easily constructed and maintained. The principles of permaculture designs are relative location every element (such as house , rice paddy, road, esc) is placed in relation to each other such that each assists the other : each element performs multiple functions ; each function is supported by many elements : energy efficient planning ; using biological resources rather than fossil fuels : energy cycling on site (both fuel and human energy) : Using and accelerating natural plant succession to establish favourable sites and soils ; poly-culture and diversity of beneficial species for a productive, interactive system ; use of edge and natural patterns for best effect. These principles can be used for any permaculture design, in any climate, and at any scale. There has been very little scientific examination of Permaculture, and as such, it must be viewed as a design philosophy.viewed as a design philosophy.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1998년도 봄 학술발표회 논문집
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• pp.245-253
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• 1998

Recently, the importance of multi-objective optimization techniques and stochastic search methods is increasing. The stochastic search methods have the concepts of the survival of the fittest and natural selection such as genetic algorithms(GA), simulated annealing(SA) and evolution strategies (ES). As many accidents of oil tankers cause marine pollution, oil tankers of double hull or mid deck structure are being built to minimize the marine pollution. For the improvement of oil tanker design technique, an efficient optimization technique is proposed in this study. Multi-objective optimization problem of weight and cost of double hull and mid deck tanker is formulated. Discrete design variables are used considering real manufacturing, and the concept of relative production cost is also introduced. The ES method is used as an optimization technique, and the ES algorithm was developed to generate a more efficient Pareto optimal set.

• 한국어병학회지
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• 제31권1호
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• pp.35-39
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• 2018

Atypical furnculosis caused by atypical Aeromonas salmonicida, is an emerging problem of farming of rockfish (Sebastes schlegeli) in Korea. In this study, protection against atypical furunculosis was compared in rockfish vaccinated with A. salmonicida formalin killed cell (FKC) and adjuvant containing FKC. The formalin inactivated A. salmonicida vaccine provided a low protection of 20% and 10% relative percent survival (RPS) at 44 and 58 days post vaccination. However, addition of adjuvant (squalene and aluminum hydroxide) into inactivated A. salmonicida vaccine clearly enhanced the level of protection showing 70% and 50% RPS at 44 and 58 days post vaccination.

• International Journal of Reliability and Applications
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• 제14권2호
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• pp.79-96
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• 2013

Exponential distribution plays a key role in engineering reliability and its applications. The exponential failure model has been studied for years. This article introduces two new preliminary test estimators for the reliability function (R(t)) in complete and censored samples from the exponential model with the use of a prior estimation (${\theta}_0$) of the mean (${\theta}$). The proposed preliminary test estimators are studied and compared numerically with the existing estimators. Computer-intensive calculations for bias and relative efficiency show that for, different values of levels of significance and for varying constants involved in the proposed estimators, the proposed estimators are far better than classical and existing estimators.