• Title/Summary/Keyword: Relationship formula

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Analysis of pneumatic braking component effects and characteristics of a diesel electric locomotive (디젤전기기관차의 공압제동 영향인자 및 특성 분석)

  • Choi, Don Bum;Kim, Min-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.11
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    • pp.541-549
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    • 2018
  • This paper deals with the braking dynamic behavior of diesel electric locomotive pulling domestic cargo and passenger vehicles. Friction coefficient, pneumatic pressure, and running resistance affecting the braking system were tested. For the friction coefficient, the Dynamo test was performed with reference to UIC 541-4. The results are analyzed by multivariate regression and the relationship between braking force and ititial velocity is presented. The pneumatic pressure were classified into service braking and emergency braking. In order to reflect the characteristics of the brake valve and piping, the pressure rising over time was measured in the vehicle. In order to reflect the external force acting on the vehicle, we carried out the test of EN 14067-4 and presented the second order polynomial formula on a running resistance. The running resistance test results were compared with other countries. The dynamic behavior of a diesel electric locomotive running on a straight flat track based on vehicle resources, friction coefficient, braking pressure, and running resistance is simulated using the time integration presented in EN 14531-1. The simulation results were compared and verified with the vehicle braking test results. The results of this study can be used to analyze the dynamic braking behavior of a train. Also, it is expected that various parameters affecting braking in vehicle design can be analyzed and used as basic data for braking performance improvement.

The Effect of Emotional Experiences on Biological Aging (정서경험과 생체노화)

  • Paik, Seo Chae;Kim, Jong Sung
    • Korean journal of health promotion
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    • v.18 no.4
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    • pp.147-158
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    • 2018
  • Background: This study was designed to investigate the effects of usual negative emotional experiences on biological aging progression of human. Methods: A total of 237 subjects who visited the Health Promotion Center at Chungnam National University Hospital from May 2013 through September 2013 was enrolled. Each subject had been drawn up a structured questionnaire about usual experiences of depression, anxiety, anger, and anger expression. The degree of biological aging progression of each subject was computed by a specific formula which consisted of chronological age and biological age reflecting obesity and aging of main organs. Results: Trait anger and low education level showed the significant correlations with biological aging (r=0.160, P=0.014, and r=-0.189, P=0.024, respectively). Trait anger and low education level solely displayed the significant $R^2s$ for biological aging in consequence of multivariate analyses; $R^2=0.044$, P=0.020, and $R^2=0.022$, P=0.038, respectively. Conclusions: This study suggests that the significant relationship between usual anger experience (i.e., trait anger) and biological aging would be present. In addition, lower education level may be related with biological aging.

20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades

  • Zhu, Sirui;Liu, Xiaoli;Xue, Mei;Li, Yu;Cai, Danhong;Wang, Shijun;Zhang, Liang
    • Journal of Ginseng Research
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    • v.45 no.2
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    • pp.295-304
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    • 2021
  • Background: Acute promyelocytic leukemia (APL) is a hematopoietic malignancy driven by promyelocytic leukemia-retinoic acid receptor A (PML-RARA) fusion gene. The therapeutic drugs currently used to treat APL have adverse effects. 20(S)-ginsenoside Rh2 (GRh2) is an anticancer medicine with high effectiveness and low toxicity. However, the underlying anticancer mechanisms of GRh2-induced PML-RARA degradation and apoptosis in human APL cell line (NB4 cells) remain unclear. Methods: Apoptosis-related indicators and PML-RARA expression were determined to investigate the effect of GRh2 on NB4 cells. Z-VAD-FMK, LY294002, and C 87, as inhibitors of caspase, and the phosphatidylinositol 3-kinase (PI3K) and tumor necrosis factor-α (TNF-α) pathways were used to clarify the relationship between GRh2-induced apoptosis and PML-RARA degradation. Results: GRh2 dose- and time-dependently decreased NB4 cell viability. GRh2-induced apoptosis, cell cycle arrest, and caspase3, caspase8, and caspase9 activation in NB4 cells after a 12-hour treatment. GRh2-induced apoptosis in NB4 cells was accompanied by massive production of reactive oxygen species, mitochondrial damage and upregulated Bax/Bcl-2 expression. GRh2 also induced PML/PML-RARA degradation, PML nuclear bodies formation, and activation of the downstream p53 pathway in NB4 cells. Z-VAD-FMK inhibited caspase activation and significantly reversed GRh2-induced apoptosis and PML-RARA degradation. GRh2 also upregulated TNF-α expression and inhibited Akt phosphorylation. LY294002, an inhibitor of the PI3K pathway, enhanced the antitumor effects of GRh2, and C 87, an inhibitor of the TNF-α pathway, reversed NB4 cell viability, and GRh2-mediated apoptosis in a caspase-8-dependent manner. Conclusion: GRh2 induced caspase-dependent PML-RARA degradation and apoptosis in NB4 cells via the Akt/Bax/caspase9 and TNF-α/caspase8 pathways.

The Study of the Origin and Transformation of the Arts of the Dao in The Canonical Scripture (《典經》中的道術思想來源與轉化運用研究)

  • Hsieh, Tsung-hui
    • Journal of the Daesoon Academy of Sciences
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    • v.36
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    • pp.267-298
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    • 2020
  • The purpose of the paper is to analyze the developmental background and practical approaches to the arts of the Dao (道術 dosul) in Daesoon Jinrihoe (大巡真理會) by tracing this concept back to its source and comparing and contrasting Daesoon Jinrihoe's usage of 'arts of the Dao' with the usage found in traditional Daoism. The paper is divided into a preface, conclusion, and two body sections. Especially significant discoveries appear in the second and third sections. In the second section, the Daoist concept of Alterable and Unalterable Degree Numbers (運度定數 yundudingshu, 'degree numbers' suggesting 'fate' or 'destiny') allows for a comparison between the Reordering Works of Heaven and Earth (天地公事 cheonjigongsa) from Daesoon Jinrihoe's The Canonical Scripture (典經 jeon-gyeong) and the Opening of Calamities to Save Humanity (開劫度人 kaijieduren) in Daoism. Here discourse can be provided regarding the cause of calamities (劫 'jie' in Chinese and 'geop' in Sino-Korean). Additionally examined are the deep grievances between divine beings and humans and the cosmic cycles of growth and decay as both of these relate to the reason for calamities. As for the resolving of calamities, there are two differing perspectives proposed by Daesoon Jinrihoe and traditional Daoism. Daesoon Jinrihoe believes that Kang Jeungsan (姜甑山) led changes and renewal through the Reordering Works of Heaven and Earth. In this context, clergy and laity play roles as assistants. However, Daoism emphasizes gaining merit from the recitation of scriptures and the collective participation of immortals rather than relying completely upon divine intervention from the Celestial Worthy of the Primordial State (元始天尊 yuanshi tianzun). In the third section, 'The Origin and Application of the Arts of the Dao (道術 daoshu),' analysis is provided regarding the origin and connotation of five directional generals (五方將 wufangjiang), the twenty-four generals (二十四將 ershijiang), the twenty-eight generals (二十八將 ershibajiang), and the forty-eight generals (四十八將 sishibajiang). Likewise examined is the relationship between the arts of the Dao in The Canonical Scripture and Thunder Rites in the Shen Xiao Lineage (道教神霄雷法 daojiao shenxiao leifa) of Daoism. Lastly, some points are made about the operation of two ceremonies: The Ceremony of Transformation and Pacing (遁甲步罡儀式 dunjiabugangyishi) and Divination through the Formula Disc of the Six Ren Gods (六壬式盤占卜 liuren shipanzhanbu).

Correlation of Left Mandibular Third Molar Development and Chronological Age (하악 좌측 제3대구치 발육과 연령 사이의 연관성)

  • Song, Min Sun;Kang, Chung-Min;Song, Je Seon;Choi, Hyung-Jun;Kim, Seong-Oh
    • Journal of the korean academy of Pediatric Dentistry
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    • v.49 no.1
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    • pp.35-44
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    • 2022
  • The aim of this study is to evaluate the development of the left mandibular third-molar development with modified Demirjian method and its relation to chronological age. A total of 1653 digital panoramic radiographs of healthy individuals aged between 7 and 23 years who visited Yonsei University Dental hospital were selected. The developmental status of the left mandibular third molars was assessed using dental maturity scoring proposed by Demirjian et al. The mean age of the first appearance of mineralization, complete crown formation, and complete root formation were around 9, 14, 21 years respectively. Statistically significant differences between males and females in the development stage of D and G were revealed that crown formation and root length completion were attained earlier in males than in females. There was significant positive relationship between age and third molar development in both sexes, and new formula was presented to estimate age of children and adolescents based on their developmental stages of third molars. In this study, the use of left mandibular third molar as a developmental marker is appropriate, and age estimation can be attained with dental maturity stage.

Estimation of Leaf Area Using Leaf Length, Leaf width, and Lamina Length in Tomato (엽장, 엽폭, 엽신장을 이용한 토마토의 엽면적 추정)

  • Lee, Jae Myun;Jeong, Jae Yeon;Choi, Hyo Gil
    • Journal of Bio-Environment Control
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    • v.31 no.4
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    • pp.325-331
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    • 2022
  • One of the most important factors in predicting tomato growth and yield is the leaf area. Estimating leaf area accurately is the beginning of an effective tomato plant growth assessment model. To this end, this study was conducted to identify the most effective model for estimating plant leaf area through the measurement of tomato plant leaves. Leaf area (LA), leaf length (L), leaf width (W), and lamina length (La) were measured for all leaves of 5 plants at two-week intervals. The correlation between LA and tomato-leaf-independent variables showed a strong positive relationship with the formulas La × W, L × W, La + W, and L + W. For LA estimation, a linear model using the formula LA = a + b (La2 + W2) gave the most accurate estimation (R2 = 0.867, RMSE = 88.76). After examining the positions of upper, middle, and lower leaves from September to December, the coefficient of determination (R2) values for each model were 0.878, 0.726, and 0.794 respectively. The most accurate estimation came from the model that used the upper leaves of the plants. The high accuracy of the upper-leaf-based model is judged by the 50% defoliation performed by farmers after October.

Evaluation of flood frequency analysis technique using measured actual discharge data (실측유량 자료를 활용한 홍수량 빈도해석 기법 평가)

  • Kim, Tae-Jeong;Kim, Jang-Gyeong;Song, Jae-Hyun;Kim, Jin-Guk;Kwon, Hyun-Han
    • Journal of Korea Water Resources Association
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    • v.55 no.5
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    • pp.333-343
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    • 2022
  • For water resource management, the design flood is calculated using the flood frequency analysis technique and the rainfall runoff model. The method by design flood frequency analysis calculates the stochastic design flood by directly analyzing the actual discharge data and is theoretically evaluated as the most accurate method. Actual discharge data frequency analysis of the measured flow was limited due to data limitations in the existing flood flow analysis. In this study, design flood frequency analysis was performed using the measured flow data stably secured through the water level-discharge relationship curve formula. For the frequency analysis of design flood, the parameters were calculated by applying the bayesian inference, and the uncertainty of flood volume by frequency was quantified. It was confirmed that the result of calculating the design flood was close to that calculated by the rainfall-runoff model by applying long-term rainfall data. It is judged that hydrological analysis can be done from various perspectives by using long-term actual flow data through hydrological survey.

An Experimental Study on Relationship Between Half-Cell Potential and Corrosion Current Density of Chloride-Induced Corroded Steel in Concrete (염해에 따라 콘크리트 속에서 부식된 철근의 반전지전위와 부식전류밀도의 상관관계에 관한 실험적 연구)

  • Jo, Sang-Hyeon;Kim, Dong-Won;Kee, Seong-Hoon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.6
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    • pp.1-13
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    • 2022
  • This study aims to investigate the feasibility of the half-cell potential (HCP) measurements on the concrete surface for evaluation of corrosion rate (or corrosion levels) of reinforcing steel in concrete. A series of experimental study is performed to measure HCP (or corrosion potential, Ecorr) and corrosion current density (icorr) of reinforcing steel in concrete cube specimens, with a side length of 200 mm. Various corrosion levels in a range of 0% to 20% of the test specimens are accelerated by impressing current to the reinforcing steel in concrete immersed in 3.0 % NaCl solution. HCP is measured in accordance with ASTM C876-15, and corrosion current density is determined by using the Stern-Geary equation and measured polarization resistance measured by electrochemical impedance spectroscopy (EIS). As a result, a numerical formula that relates HCP and icorr in the test specimen is established by a regression analysis of the measured data in this study. It is observed that HCP is linearly correlated with log(icorr) with a R2 greater than 0.87, which is less affected by the experimental variables such as concrete mixture proportion, diameter of reinforcing steel and the amount of applied current in this study. These results exhibit that HCP measurements could be effective for evaluation of corrosion rate (or corrosion levels) of reinforcing steel in concrete in the case of exposed to a certain consistent environment.

Growth Modeling of Perilla frutescens (L.) Britt. Using Expolinear Function in a Closed-type Plant Factory System (완전제어형 식물공장에서 선형지수함수를 이용한 들깨의 생육 모델링)

  • Seounggwan Sul;Youngtaek Baek;Young-Yeol Cho
    • Journal of Bio-Environment Control
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    • v.32 no.1
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    • pp.34-39
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    • 2023
  • Growth modeling in plant factories can not only control stable production and yield, but also control environmental conditions by considering the relationship between environmental factors and plant growth rate. In this study, using the expolinear function, we modeled perilla [Perilla frutescens (L.) Britt.] cultivated in a plant factory. Perilla growth was investigated 12 times until flower bud differentiation occurred after planting under light intensity, photoperiod, and the ratio of mixed light conditions of 130 μmol·m-2·s-1, 12/12 h, red:green:blue (7:1:2), respectively. Additionally, modeling was performed to predict dry and fresh weights using the expolinear function. Fresh and dry weights were strongly positively correlated (r = 0.996). Except for dry weight, fresh weight showed a high positive correlation with leaf area, followed by plant height, number of leaves, number of nodes, leaf length, and leaf width. When the number of days after transplanting, leaf area, and plant height were used as independent variables for growth prediction, leaf area was found to be an appropriate independent variable for growth prediction. However, additional destructive or non-destructive methods for predicting growth should be considered. In this study, we created a growth model formula to predict perilla growth in plant factories.

Measurement of the Axial Displacement Error of a Segmented Mirror Using a Fizeau Interferometer (피조 간섭계를 이용한 단일 조각거울 광축방향 변위 오차 측정)

  • Ha-Lim, Jang;Jae-Hyuck, Choi;Jae-Bong, Song;Hagyong, Kihm
    • Korean Journal of Optics and Photonics
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    • v.34 no.1
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    • pp.22-30
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    • 2023
  • The use of segmented mirrors is one of the ways to make the primary mirror of a spaceborne satellite larger, where several small mirrors are combined into a large monolithic mirror. To align multiple segmented mirrors as one large mirror, there must be no discontinuity in the x, y-axis (tilt) and axial alignment error (piston) between adjacent mirrors. When the tilt and piston are removed, we can collect the light in one direction and get an expected clear image. Therefore, we need a precise wavefront sensor that can measure the alignment error of the segmented mirrors in nm scale. The tilt error can be easily detected by the point spread image of the segmented mirrors, while the piston error is hard to detect because of the absence of apparent features, but makes a downgraded image. In this paper we used an optical testing interferometer such as a Fizeau interferometer, which has various advantages when aligning the segmented mirror on the ground, and focused on measuring the axial displacement error of a segmented mirror as the basic research of measuring the piston errors between adjacent mirrors. First, we calculated the relationship between the axial displacement error of the segmented mirror and the surface defocus error of the interferometer and verified the calculated formula through experiments. Using the experimental results, we analyzed the measurement uncertainty and obtained the limitation of the Fizeau interferometer in detecting axial displacement errors.