• Genomics & Informatics
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• v.17 no.1
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• pp.11.1-11.7
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• 2019

Athletic performance is a complex multifactorial trait involving genetic and environmental factors. The heritability of an athlete status was reported to be about 70% in a twin study, and at least 155 genetic markers are known to be related with athlete status. Mitochondrial DNA (mtDNA) encodes essential proteins for oxidative phosphorylation, which is related to aerobic capacity. Thus, mtDNA is a candidate marker for determining physical performance. Recent studies have suggested that polymorphisms of mtDNA are associated with athlete status and/or physical performance in various populations. Therefore, we analyzed mtDNA haplogroups to assess their association with the physical performance of Korean population. The 20 mtDNA haplogroups were determined using the SNaPshot assay. Our result showed a significant association of the haplogroup F with athlete status (odds ratio, 3.04; 95% confidence interval, 1.094 to 8.464; p = 0.012). Athletes with haplogroup F ($60.64{\pm}3.04$) also demonstrated a higher Sargent jump than athletes with other haplogroups ($54.28{\pm}1.23$) (p = 0.041). Thus, our data imply that haplogroup F may play a crucial role in the physical performance of Korean athletes. Functional studies with larger sample sizes are necessary to further substantiate these findings.

• Development and Reproduction
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• v.13 no.2
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• pp.97-103
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• 2009

Genomic DNA samples isolated from four geographical freshwater crab (Eriocheir sinensis) populations collected in the inland of the Korean Peninsula (Gunsan, Paju, and Nampo) and a Chinese site, were used for PCR amplification. Seven decamer primers generated 19 specific loci (19/243 loci, 7.81%) in the Gunsan population, 32 (32/215 loci, 14.88%) in the Paju population, 19 (19/231 loci, 8.23%) in the Nampo population and 62 (62/340 loci, 18.24%) in a Chinese population. The average 8.9 specific loci exhibited inter-individual-specific characteristics, thus revealing DNA polymorphisms in the Chinese population. The number of unique shared loci to each population and number of shared loci by the four populations were generated by molecular analysis using seven primers in four populations. 35 unique shared loci to each population, with an average of 5.0 per primer, were observed in the Gunsan population, and 50 loci, with an average of 7.1 per primer, were observed in the Chinese population. The hierarchical dendrogram indicates three main branches: cluster 1 (GUNSAN 01$\sim$GUNSAN 05, PAJU 06$\sim$PAJU 10 and NAMPO 11$\sim$NAMPO 15) and cluster 2 (CHINESE 16, 17, 18, 19 and 20). Conclusively individual no. 20 of the PAJU 10 freshwater crab was most distantly related to CHINESE no. 20 (genetic distance = 0.667). Taken together, these results demonstrate the potential of RAPD analysis to identify diagnostic markers for the identification of four freshwater crab populations.

• The Korean Journal of Applied Statistics
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• v.34 no.5
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• pp.823-835
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• 2021

Identification of factors influencing regional population is critical for establishing government's population policies as well as for improving residents' social, economic and cultural well-being in the region. In this study we analysed the data from 2019 Population Housing Survey in Korea to identify the factors affecting the population size in each of the three regions: Seoul, metropolitan cities, and provincial regions. We applied a Bayesian quantile regression to account for asymmetry and heteroscedasticity of data. The analysis results showed that the effects of factors vary greatly between the three regions of Seoul, metropolitan cities, and provincial regions as well as between sub regions within the same region. These results suggest that population-related variables have very heterogeneous characteristics from region to region and therefore it is important to establish customized population policies that suit regional characteristics rather than uniform population policies that apply to every region.

• Development and Reproduction
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• v.19 no.4
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• pp.259-264
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• 2015

Genomic DNA samples isolated from geographical purplish Washington clam (Saxidomus purpuratus) were obtained from three different regions in the Korean Peninsula: Geoje (Geoje population; GJP), Gunsan (Gunsan population; GSP) and a site of North Korea (North Korea population; NKP). The seven primers generated the total 369 loci that can be scored from the GSP clam population. 356 fragments were generated from the NKP clam population. The complexity of the banding patterns varies dramatically between the primers and three localities. In this study, 319 loci were identified in the purplish Washington clam from Geoje and 369 in the clam population from Gunsan: 221 specific loci (69.3%) in the GJP clam population and 300 (81.3%) in the GSP population. These results demonstrate that the primer detected a large quantity of specific fragments, suggesting that the genetic variation in the GSP is higher than in the GJP population. In particular, the BION-28 primer gave DNA profiles with more fragments than the other six primers in the NKP population. The oligonucleotides primer BION-75 produced 21 unique loci to each population, which were ascertaining each population, approximately 250 bp, 300 bp and 400 bp, in the GJP population. Outstandingly, the primer BION-50 detected 21 shared loci by the three populations, major and/or minor fragments of sizes 150 bp, which were matching in all samples. With regard to average bandsharing value (BS) results, individuals from GJP population (0.743) displayed higher bandsharing values than did individuals from GSP population (0.606). In the present study, the dendrogram gained by the seven oligonucleotides primers indicates three genetic clusters: cluster 1 (GEOJE 01 ~ GEOJE 07), cluster 2 (GUNSAN 08 ~ GUNSAN 14), cluster 3 (N.KOREA 15 ~ N.KOREA 21). Among the twenty one clams, the shortest genetic distance that revealed significant molecular differences was between individuals 08 and 09 from the NKP population (genetic distance = 0.073), while the longest genetic distance among the twenty-one individuals that demonstrated significant molecular differences was between individuals GEOJE no. 03 and GUNSAN no. 09 (genetic distance = 0.669). Comparatively, individuals of GJP population were properly closely related to that of NKP population, as revealed in the hierarchical dendrogram of genetic distances. In due course, PCR analysis has revealed the significant genetic distance among three purplish Washington clam populations. PCR fragments discovered in this study could be valuable as a DNA marker of the three geographical clam populations to distinguish.

• Journal of Korean Academy of Oral Health
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• v.42 no.4
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• pp.159-166
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• 2018

Objectives: The aim of this study was to investigate the association between masticatory ability, oral health-related quality of life, and cognitive function in an elderly population using structural equation modeling. Methods: A total of 308 subjects, aged 65 years and over, were recruited from the senior citizen center in Daegu, South Korea and provided consent for inclusion in the study. The Korean version of the Mini-Mental State Examination (K-MMSE) was used to assess the level of cognitive function. Masticatory ability was evaluated through chewing tests, patient-perceived masticatory function and, measurement of relative occlusal forces on molar teeth using the T-Scan $III^{(R)}$ system. All data were analyzed using ${\chi}^2$ tests, t-tests, and one-way ANOVA in SPSS version 23.0 for windows. Structural equation modeling was performed using SPSS AMOS version 22.0. Results: There was a significant association between cognitive function and molar teeth occlusal force. Ability of food chewing score and patient-perceived masticatory function could affect oral health-related quality of life (P>0.05). Higher occlusal forces on molar teeth, compared to anterior teeth, positively correlated with higher cognitive function. Conclusions: These results suggest that an individual's oral health condition could affect molar teeth occlusal forces and may be related to a risk of developing dementia. Therefore, there is a need for implementing nation-wide policies to improve oral health, such as masticatory function, in the elderly population.

• Journal of applied mathematics & informatics
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• v.30 no.3_4
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• pp.677-683
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• 2012

W.Choi([1]) obtains a complete description of ergodic property and several property by making use of the semigroup method. In this note, we shall consider separately the martingale problems for two operators A and B as a detail decomposition of operator L. A key point is that the (K, L, $p$)-martingale problem in population genetics model is related to diffusion processes, so we begin with some a priori estimates and we shall show existence of contraction semigroup {$T_t$} associated with decomposition operator A.

• Journal of Nutrition and Health
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• v.27 no.1
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• pp.71-78
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• 1994

Recently the incidence of hemorrhoids has been increased. There were various factors related to hemorrhoids, the amount of fiber intake was known as one of them. And so we performed this case-control study to investigate the association of hemorrhoids and fiber intake. The data was obtained by the combination of self-administered questionnaire and personal interview. The study population was consisted of matched 156 pairs, the cases were selected from S-hospital in Seoul, the age and sex matched control from the general population. The statistical analysis was performed by matched-analysis. The results summarized as follow : 1) As socio-economic status were low, the odds ratio of hemorrhoids were high. 2) There was significant association between hemorrhoids and regularity of eating time rather than regularity of defecation. 3) The odds ratio of hemorrhoids was 3 times higher in the presence of constipation. 4) The incidence of hemorrhoids was influenced by psychological characteristics such as somatization, obsessive-compulsive, depression, and anxiety. 5) Fiber intake was significantly lower in the cases compared to the controls. When the constipation was controlled, the fiber intake was still lower in the cases. These data provide additional evidence that the fiber intake was related to hemorrhoids.

• International Journal of Contents
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• v.14 no.2
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• pp.30-34
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• 2018

There are several problems facing our society today that are caused by demographic changes, such as an increase in the ageing population. The rapid increase in the aging population leads to increases in medical costs and a higher demand for care services for the elderly. The needs and burdens associated with elderly care are growing, but the human resources and costs to meet these needs are limited. Welfare technology has been suggested as an effective way to solve the discrepancy between higher welfare needs and limited resources. This study aims to explore the current trends and challenges of using welfare technology related to elderly care through literature review. Practical ways to expand uses of welfare technology are also provided. In order to make effective and practical use of welfare technology, public awareness and education, the cooperation of related organizations, the expansion and utilization of Living Labs, and the development and adoption of welfare technology are required.

• Journal of the Korean Institute of Landscape Architecture
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• v.21 no.2
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• pp.1-7
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• 1993

This study suggests one hypothesis: The strength between the catchment foreces of urban community parks can be represented to a gravity model. The gravity model is derived from the related of two subjects, witch is related with their distance. A grvity model for the catchments between parks is represented as followed formula: Iij=${\alpha}$${\times}$ $\frac{Pi$.$Pj}{${\beta}$r}$(formula) Here, Iij is a total number of the vistors of park i and j in a year. Pi is population of the catchment area of park i. Pj is population of the catchment area of park j. ${\alpha}$and, ${\beta}$ are parameters. This formula is testified in the case of Chong-ju community parks.

• 한국공간정보시스템학회:학술대회논문집
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• 2007.06a
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• pp.280-285
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• 2007

Since the human civilization, people's livelihood is dependent on natural resources primarily on forest. Human dimensions such as population, poverty, agricultural expansion and infrastructure development are some of the underlying factors and their interrelated associations which could play a vital role in deforestation and forest degradation. This process is not only related to the human population but also connected to the various socioeconomic factors. This paper focuses to link the spatio-temporal extent of population, poverty incidence and forest dependency and their severity on Terai forest of Nepal. Secondary data on censuses were used. ArcGIS and descriptive statistics were also used for data analysis. Based on analysis & literature review we concluded that population, poverty and forest dependency have largely expanded over time in Terai and their interrelated associations substantively influence on deforestation. However, the direct relationship of such factors with deforestation and forest degradation found to be incompatible, complex and hard to perceive with fragmented and inconsistency censuses data. So, deforestation and forest degradation issues intertwined with socioeconomic factors need detailed analysis to comprehend where these linkages are still unravel.