• Title/Summary/Keyword: Regulation improvement

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Research on Safety and Quality Regulatory Policy for Assistive Products (보조기기 안전·품질관리 방안 연구)

  • Kim, Hye-Won;Kim, Dong-A;Seo, Won-San;Kim, Jang-Hwan;Ko, Myeong Han;Son, Byung-Chang;Yi, JinBok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.805-813
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    • 2018
  • The research was conducted with the purpose of providing effective safety and quality control system for assistive products for handicapped those are used extensively. Assistive products couldn't be classified independently due to collision with the act of medical device and lack in legal basis. The issues about safety and quality have been solved by other legal frames on a case by case basis. We couldn't find any abroad case of independent safety and quality control policy. For the practical solution, this article suggested hybrid classification system mixed with existing policies. Each classified branches are allocated to the appropriate policy of safety and quality control so those are ease of understanding and prospect. And also a delicacy process was suggested not to leave off any assistive products. Through these suggests of the improvement it is expected that blind areas of safety and quality control for assistive products for handicapped could be solved and identity of assistive products could be established to provide product safety for handicapped and boost relevant industries.

Characteristics of Non-nano Needle Type Zinc Oxide and Its Application in Sunscreen Cosmetics (Non-nano 막대형 산화아연의 특성 및 자외선 차단용 화장품에의 응용)

  • Chong, Kyo Un;Xuan, Song Hua;Yoon, Yeo Min;Kim, Sang-uk;Choi, Bou Kun;Lee, Sung Ho;Park, Soo Nam;Lee, Jong Sung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.47 no.1
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    • pp.1-7
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    • 2021
  • With increasing interest in the effectiveness and safety of sunscreen worldwide, research on the development of new inorganic sunscreen is also gaining momentum. In the present study, non-nano sized needle type zinc oxide, which can meet the regulation of nano-material as a recent problem, has been synthesized and surface-modified with cetyl alcohol to obtain needle type zinc oxide powder. Here, we also investigated their physical properties and evaluated their potential application as sunscreens. As a result of the experiment, the sunscreen with needle type zinc oxide powder, which was non-nano, showed similar UV-protection properties and transparency compare to that of 40nm size zinc oxide. It was further confirmed that the UV blocking effect was significantly increased when the needle type zinc oxide dispersion was applied to the sunscreen. Therefore, although the needle type zinc oxide is non-nano (200 nm) material, it has the potential to be applied to the product as an excellent transparency (improvement of whiteness), UV protection efficacy and smooth texture.

Current status analysis for the protection of emotional workers in Pyeongtaek area (평택지역 감정노동자 보호를 위한 현황분석)

  • Jung, Hye Jung;Jung, Su Hyun
    • Journal of the Korea Convergence Society
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    • v.12 no.8
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    • pp.55-60
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    • 2021
  • In order to prepare basic data for research on the protection of emotional workers in Pyeongtaek with the support of Pyeongtaek City, this study conducted a survey centered on 104 counselors classified as emotional laborers. Based on the results of the survey centered on 104 emotional workers, basic research data on the difficulties of emotional workers can be prepared, and protection methods for emotional workers who are currently interested in each local government can be found. As a result of selecting a sample centering on counselors in Pyeongtaek City for a survey on the actual condition of emotional workers, and conducting a survey based on the selected samples, it was found that emotional workers did not find their rights to human rights and were not protected even in the workplace. Currently, a bill to protect emotional workers is being announced, but it is not protected, so it is confirmed that system improvement is necessary. This study focused on 104 items that were significant through pre-processing among the recovered questionnaires. It was analyzed using SPSS, R, and it was confirmed that there is a need for a regulation that can provide an institutional device in Pyeongtaek City. In this study, it is judged that it is necessary to prepare a protective device for emotional workers by selecting more samples corresponding to the occupational group of emotional workers.

Countermeasures to the Introduction of Low Caloric Gas Fuel for Natural Gas Engine (저열량 가스 적용에 따른 천연가스엔진의 대응 방안 연구)

  • Park, Cheol-Woong;Kim, Chang-gi;Oh, Se-Chul;Lee, Jang-Hee
    • Journal of the Korean Institute of Gas
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    • v.25 no.2
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    • pp.34-41
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    • 2021
  • In order to cope with the problems that may occur when the natural gas used in Korea becomes low in calories, the problems that may have to the domestic industrial gas equipment must be identified in advance, and based on this, countermeasures for efficient use of energy must be preceded. In this study, in order to solve the problem of deterioration of engine output performance and efficiency due to the introduction of low calorific gas when using a lean-burning natural gas engine that complies with the EURO-6 regulation, specific control plans and results based on the experiment are intended to be presented. In order to identify the improvement effect by the control variable represented by the ignition timing under the full load condition at the engine speed of 1,400 rpm and 550 Nm, 2,100 rpm, which is the engine speed at the rated operation condition, the thermal efficiency and exhaust gas characteristics were identified and optimized by changing the ignition timing for each gas fuel. In the case of pure methane, which shows the lowest value based on the torque under the full load condition, if the ignition timing is advanced by about 2 CAD from the reference ignition timing, the torque can be compensated without a large increase in NOx emission.

Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway

  • Ni, Jingyu;Liu, Zhihao;Jiang, Miaomiao;Li, Lan;Deng, Jie;Wang, Xiaodan;Su, Jing;Zhu, Yan;He, Feng;Mao, Jingyuan;Gao, Xiumei;Fan, Guanwei
    • Journal of Ginseng Research
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    • v.46 no.2
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    • pp.235-247
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    • 2022
  • Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular mechanisms involved. Methods: The effects of ginsenoside Rg3 on heart and mitochondrial function were investigated by treating TAC-induced heart failure in mice. The mechanism of ginsenoside Rg3 for improving heart and mitochondrial function in mice with heart failure was predicted through integrative analysis of the proteome and plasma metabolome. Glucose uptake and myocardial insulin sensitivity were evaluated using micro-positron emission tomography. The effect of ginsenoside Rg3 on myocardial insulin sensitivity was clarified by combining in vivo animal experiments and in vitro cell experiments. Results: Treatment of TAC-induced mouse models with ginsenoside Rg3 significantly improved heart function and protected mitochondrial structure and function. Fusion of metabolomics, proteomics, and targeted metabolomics data showed that Rg3 regulated the glycolysis process, and Rg3 not only regulated glucose uptake but also improve myocardial insulin resistance. The molecular mechanism of ginsenoside Rg3 regulation of glucose metabolism was determined by exploring the interaction pathways of AMPK, insulin resistance, and glucose metabolism. The effect of ginsenoside Rg3 on the promotion of glucose uptake in IR-H9c2 cells by AMPK activation was dependent on the insulin signaling pathway. Conclusions: Ginsenoside Rg3 modulates glucose metabolism and significantly ameliorates insulin resistance through activation of the AMPK pathway.

A Study on Ways to Improve Safety Management through Analysis of Fire Cases in Multiple-user Buildings (다중이용업소의 화재사례 분석을 통한 안전관리 개선방안 연구)

  • Lee, Jae Wook
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.3
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    • pp.191-201
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    • 2022
  • In this study, we are going to derive problems for fire and safety management in multiple-user Buildings and suggest improvement measures to prevent recurrence through analysis of legal operation status for safety management of multiple-user Buildings and case studies of large-scale fires in multiple-user Buildings. For this study, first, the current state of the industry and fire occurrence status were investigated through theoretical considerations of the multi-use industry, and then the previous research on the multi-use industry was analyzed. and by analyzing the legal and institutional status of multiple-user Buildings, problems were derived through cases such as the Jecheon fire in Chungcheongbuk-do, the Inhyeon-dong fire in Incheon, and the Songpa-gu fire in Seoul. As a result, first, the necessity of strengthening the initial fire response capability. Second, thorough maintenance and management of emergency exits. Third, the need for rational regulation of upholstery. Fourth, reinforcement of fire safety education and training. Fifth, strengthening of installation standards for firefighting and safety facilities. Sixth, we derive the result that it is necessary to raise awareness about safety management, compare and analyze it with legal and institutional contents, and suggest solutions accordingly. When looking at the causes of fires in multi-use buildings, building owners, business owners, and employees think that there is no possibility of a fire occurring in their business premises, so there is a lack of awareness. It is necessary to raise awareness through education and publicity of firefighters and related administrative agencies.

Recent Studies of Breast Cancer in Traditional Chinese Medicine Journals (중의학 논문에 나타난 유방암의 연구 동향에 대한 고찰 - 중의학 논문을 중심으로 -)

  • Jerng, Ui-Min;Jeong, Jong-Soo;Park, Jae-Woo;Jung, Hyun-Sik;Yoon, Seong-Woo
    • The Journal of Korean Obstetrics and Gynecology
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    • v.22 no.1
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    • pp.263-278
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    • 2009
  • Purpose: The purpose of this study is to research trends in the study of breast cancer in Traditional Chinese Medicine (TCM) and to establish the further direction for its study. Methods: We reviewed TCM papers published in the last 29 years (1979-2008). Results: 1. We researched 49 papers and the patterns of study were as follows: in vitro studies were 27 papers (55.1%), in vivo studies were 9 papers (18.4%) and clinical studies were 19 papers (38.8%). 2. In vitro studies on breast cancer research in TCM were focused on cytotoxicity (17 papers) and apoptosis (8 papers). Most of in vivo studies (6 papers) were done for the purpose of inducing growth suppression of tumor cell after administration of the test drug. Each drug acted on this effect through various types of mechanism. 3. Unlike in vitro and in vivo studies, clinical studies on growth suppression of tumor cell were rare (4 papers). Most of the studies were focused on reduction of side effect of chemotherapy or synergistic effect with chemotherapy (7 papers), immune regulation (7 papers), and improvement of quality of life (6 papers). 4. Among the treatment method we reviewed, 'Runing Ⅱ(Ⅱ號方)' was the only medication that further studied as clinical trial after experimental study. 5. Since almost all studies have defects like poorly designed model or insufficient data description, it was difficult to make any definite conclusion about these studies. Conclusion: More subsequent clinical studies based on experimental study will be needed afterwards. Strict and high-level study design with detailed description will be needed in further study.

The moderate effects of father's attachment between self-esteem and adolescents' internalizing problem behavior -Focusing on the male students- (자아존중감과 청소년 외현화 문제행동 간의 영향과 아버지애착의 조절효과 연구-남학생을 중심으로-)

  • Kim, Min Joo;Ji, Eun Gu;Jo, mi jeong
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.6 no.8
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    • pp.63-72
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    • 2016
  • The main purpose of this study was to empirically validate whether a factor in reducing youth externalizing problem behaviors impact analysis and affection between father and youth self-esteem externalizing problem behavior through effective regulation. The survey was conducted by the researcher who visits the school to collect the sample data by random sampling method on 336 male students at D area. After delating the 38 insincere questionnaires, final 298 data were analyzed. Using SPSS 21.0, the simple correlational analysis was conducted to decide the relationship among the variables and in order to know the reciprocal model, hierarchical multiple regression analysis was implemented. The results showed the esteem and the affection his father on a statistically significant effect on youth externalizing problem behavior, father attachment had the effect of regulating the relationship between self-esteem and externalizing problem behavior. Through these results through the self-esteem Improvement Plan of the Father and the love of young people and to promote a proposal for reducing externalizing problem behavior.

An Empirical Study on the Effect of International Standard Certification Execution and CRM Satisfaction on Business Performance in B2B Transaction (B2B거래에서 국제표준인증 실행과 CRM만족도가 사업성과에 미치는 영향에 대한 실증적 연구)

  • Kim, Chang-Bong;Park, Sang-An;Jung, Jin-Young
    • Korea Trade Review
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    • v.42 no.2
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    • pp.319-344
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    • 2017
  • The international standard certification evaluates the extend to which the supplier satisfies the international standard certification standards of the supplier of the product and the service, recognizes the quality assurance ability and reliability of the supplier, thereby resolving the international trade regulation that can occur to various fields and strengthening the network of the global partnership it is making an important contribution. Therefor, in this study, the survey was conducted on 153 companies of Korean import and export companies. The research method was empirically analyzed by the structural equation model. The results of the hypothesis test of this study are as follows. First, resource management factors among the international standard certification factors in the global trade supply chain integration had a positive effects on CRM satisfaction. Second, the measurement, analysis and improvement factors of international standard certification factors had a positive effects on CRM satisfaction. Third, CRM satisfaction has a positive effects on business performance. Through this study, it is concluded that the Korean import and export companies have an important role in improving the business performance of the global trade partners.

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Antidepressant Effect and Mechanism of Picea mariana Essential Oil on Reserpine-Induced Depression Model Mice

  • Ying Wang;Guofeng Shi;Yixi Zeng;Juting Li;Yongyu Wu;Jiahui Zheng;Anjing Xu;Yanqing Ma;Lanyue Zhang;Hui Li
    • Journal of Microbiology and Biotechnology
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    • v.34 no.9
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    • pp.1778-1788
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    • 2024
  • The disturbance of brain biochemical substances serves as a primary cause and aggravating factor of depression. This study aimed to investigate the principal components of Picea mariana and its effect on reserpine-induced depression mice,w ith its relationship with brain central transmitters and related proteins. The main constituents of P. mariana essential oil (PMEO) were analyzed by GC-MS spectrometry. The quiescent time in the tail suspension test (TST) and forced swim test (FST), along with the weight change of the mice was detected. The number of normal neurons was quantified through Nissl staining. Immunohistochemistry was employed to determine the levels of 5HT-1A and 5HT-2A in the brain. Western blotting was utilized to detect 5HT-2A, CRF and TrkB protein levels. RTqPCR was used to detect the mRNA levels of 5HT-1A, 5HT-2A, TrkB, CRF, and BDNF. The main active ingredients of PMEOs were (-) -bornyl acetate (44.95%), γ-Terpinene (14.17%), and β-Pinene (10.12%). PMEOs effectively improved the retardation and weight loss due to anorexia in depression-like mice. This improvement was associated with an increase in the number of normal neurons. After administering different doses of PMEOs, the levels of 5HT-1A, 5HT-2A, CRF, and TrkB were found to be increased in brain tissue. RT-qPCR revealed that the mRNA levels of CRF, 5HT-1A, and 5HT-2A were generally upregulated, whereas TrkB and BDNF were downregulated. PMEO can effectively alleviate depression induced by reserpine, which may be attributed to its regulation of 5HT-1A, 5HT-2A, CRF and TrkB protein expression, thus reducing brain nerve injury.