• 해양환경안전학회지
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• 제19권3호
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• pp.270-276
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• 2013

The educational process and result of onboard training should be evaluated according to the 1995 Amendments to the International Convention on Standards of Training, Certification and Watch-keeping for seafarers(STCW), 1978. In particular, the revised Convention requires that a trainee's seagoing service must be recorded in each cadet's Training Record Book approved by the maritime administration responsible for the issuance of certificates of competency. Trainees for certification under regulation III/1 of the STCW Convention are required to complete an approved on-board training programme. The purpose of this paper is to understand the compliance of the education for an approved on-board training programme. The questionnaire was distributed among 110 cadets being trained on board the training ship of the maritime college of the Mokpo National Maritime University. In this study, we conducted the questionnaire survey which is related to the on-board training programme such as marine engineering; controlling the operation of the ship and care for persons on board; electrical, electronic and control engineering; etc. The survey revealed that onboard training program was normally satisfactory, however, lack of practical training tools and time have accounted for most of the reasons for dissatisfaction. Therefore, it is our goal to enhance the satisfactory value of onboard training education by analyzing the reason of the dissatisfaction.

• 정보보호학회논문지
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• 제25권6호
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• pp.1607-1620
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• 2015

서버 Privilege 계정은 법규에 따라 운영 되어야 한다. 그러나 농협은 서버 Privilege 계정 운영에 대한 법규 미준수와 운영 미흡으로 서버의 모든 데이터가 삭제되는 농협 전산망 해킹 사건이 발생하였다. 본 연구에서는 금융회사의 서버 Privilege 계정 운영방식을 결정하기 위한 모델을 제시하기 위해 금융회사의 Privilege 계정 운영 현황을 조사하여 문제점을 도출하고, 개선방안을 제시한다. 또한, Privilege 계정 운영현황 조사를 통해 선정된 평가요인은 AHP(Analytic Hierarchy Process)를 사용하여 의사결정 모델과 공식을 제시하고 검증한다.

• 동의생리병리학회지
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• 제24권5호
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• pp.770-778
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• 2010

To establish the fundament for EBM of Traditional Korean Medicine, the papers on Pyeongwi-san (Pingwei-san) frequently used in medical institutions of Traditional Korean Medicine were analyzed through researching domestic and international papers. The papers were classified by the registration of domestic or international journals, the year of publishment, experimental fields and the kinds of studies on biological activities. Of total 518 papers on Pyeongwi-san (Pingwei-san), 32 volumes were selected according to selection creteria. 20 volumes were published in domestic journals, 11 in Chinese journal and 1 in Japanese journal. The papers on instrumental analyses reported the quantification of standard compounds of herbal medicines in Pyeongwi-san (Pingwei-san) using HPLC, GC-MS. The papers on biological activities of Pyeongwi-san (Pingwei-san) showed improvement of gastrointestinal activity and water-electrolyte metabolism, immune regulation, anti-oxidant, anti-inflammatory, analgesic, anti-convulsant activities, hypnotic duration, blood pressure regulation, hepatic protection, congestive heart failure, anti-cancer activities. Further studies including gastrointestinal activity need to be preceeded to establish the fundament for EBM of Pyeongwi-san (Pingwei-san).

• Biomolecules & Therapeutics
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• 제28권3호
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• pp.240-249
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• 2020

Despite the therapeutic effect of mesenchymal stem cells (MSCs) in ischemic diseases, pathophysiological conditions, including hypoxia, limited nutrient availability, and oxidative stress restrict their potential. To address this issue, we investigated the effect of melatonin on the bioactivities of MSCs. Treatment of MSCs with melatonin increased the expression of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α). Melatonin treatment enhanced mitochondrial oxidative phosphorylation in MSCs in a PGC-1α-dependent manner. Melatonin-mediated PGC-1α expression enhanced the proliferative potential of MSCs through regulation of cell cycle-associated protein activity. In addition, melatonin promoted the angiogenic ability of MSCs, including migration and invasion abilities and secretion of angiogenic cytokines by increasing PGC-1α expression. In a murine hindlimb ischemia model, the survival of transplanted melatonin-treated MSCs was significantly increased in the ischemic tissues, resulting in improvement of functional recovery, such as blood perfusion, limb salvage, neovascularization, and protection against necrosis and fibrosis. These findings indicate that the therapeutic effect of melatonin-treated MSCs in ischemic diseases is mediated via regulation of PGC-1α level. This study suggests that melatonin-induced PGC-1α might serve as a novel target for MSC-based therapy of ischemic diseases, and melatonin-treated MSCs could be used as an effective cell-based therapeutic option for patients with ischemic diseases.

• 대한본초학회지
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• 제31권1호
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• pp.1-5
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• 2016

Objectives : The purpose of this study was to investigate inhibitory effects of steamed Polygonatum odoratum extract (POE) on insulin resistance in rat skeletal muscle cells, L6 cells.Methods : Polygonatum odoratum (P. odoratum) extract was extracted with ethyl acetate. Activity of α-glucosidase in POE was measured for blood glucose regulation. MTT assay was examined for cell toxicity. Western blot analysis for measurement of adiponectine, peroxisome proliferator-activated receptorγ (PPARγ), insulin receptor substrate (IRS), glucose transporter 4 (Glut-4) and phosphorylation of serine/threonine-specific protein kinase (Akt) expressions were performed. Akt signaling pathway were analyzed with LY294002, which is a specific PI3K/Akt inhibitor.Results : The results revealed that POE inhibited α-glucosidase activity. Treatment of POE in L6 cells inhibited the differentiation of L6 cells compared to those of vehicl control. Additionally, protein expressions of adiponectine, PPARγ, IRS and Glut-4 were significantly regulated compared to those of vehicle control (p < 0.05), respectively. Futhermore, phosphorylation of Akt was increased in L6 cells treated with POE compared to that of vehicle control (p < 0.05). pAkt expression was significantly accentuated with Akt inhibitor (LY294002).Conclusions : These results suggest that POE may have potential as a natural agent for prevention/improvement of diabetes, especially, regulation of blood glucose. Therefore, further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

• 대한치과의사협회지
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• 제56권9호
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• pp.479-490
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• 2018

3D printing technology supporting the specific patient medical services is actively being implemented in dentistry. The purpose of this study is to introduce the legal and institutional considerations to the medical practitioners in dentistry who must observe when they manufacture medical devices using 3D printers, and to provide a ways to activate and enhance their utilization in the domestic approval point of view for medical devices. Through the public data of government agencies and related organizations, the statutory system and compliance matters related to the manufacture of 3D printing medical devices have been examined and reviewed for the government's improvement efforts. Through the study, the government has been actively improving the system and making policy, but the active interest and participation of medical professionals and related workers are continually required to solve the problems which are scattered. 3D printing technology is expected to be more frequently utilized in the field of dentistry in near future. Therefore, it is essential to establish measures to improve the regulation through continuous cooperation with the related ministries with the long-term point of view enhancing smooth entry to the market for the medical devices by taking data from the continued research.

• 한국수소및신에너지학회논문집
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• 제20권2호
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• pp.161-167
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• 2009

The regulation of the $CO_2$ emit from vehicles have become much more stringent in recent years. This stringent regulation is more request vehicle manufacturers to develop the alternative fuel vehicles for reducing exhaust emissions. LPG fuel is more clean energy compares with gasoline and diesel fuel. Especially, $CO_2$ emission of LPG Vehicle is less than gasoline vehicle and almost equal to diesel vehicle. For this reason, recently korean government is extending LPG fuel for hybrid car and light duty vehicle. In domestic, Propane is mixing $15{\sim}30%$ to butane for improvement of cold start at winter season. Therefore, In this paper was investigated that the characteristics of emissions according to propane mixing rate with 0, 10, 20, 30% were compared and analyzed by the vehicle test using LPG vehicle according to the FTP75 mode. It was also investigated the characteristics of nano-particle emit with propane mixing rate.

• 농촌계획
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• 제21권4호
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• pp.45-53
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• 2015

Agriculture, rural landscapes are accompanied by a variety of environmental issues. Therefore, it is necessary to study on biodiversity and ecosystem services. Horticulture complex is low groundwater recharge function, it can be evaluated as a facility that biodiversity is impaired. The ecosystem services in agricultural landscapes were obtained 19 kinds of functions. Experts survey Groundwater recharge function (4.13) teeth chapter higher, Water storage (4.05), Amphibian & Reptile habitat (3.96), Aquatic insect habitat (3.92), Flood control (3.87), Water purification (3.86), Avian habitat (3.76 ), Creating landscape (3.74), Vegetation diversity (3.71), Experience, Education (3.69), Biological control (3.48), Fishery habitat (3.42), Climate regulation (3.30), Mammal habitat (3.30), Air quality regulation (3.25 ), Mainenance of genetic diversity (3.25), were analyzed in order Rest area (3.14). Improving capabilities in the Detention Pond, Wetland, Green space, Corridor, Non-Chemical, Program development, Green spaces, Rainwater storage facilities, Water cycle system, Surface water storage facilities, Infiltration trench, Water purification facilities, Permeable pavement. Environmentally friendly, and to contribute to sustainable agricultural development through ecological planning.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2004년도 춘계학술대회논문집
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• pp.308-311
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• 2004

It is reported that there is a limit in increasing heavy-weight impact noise isolation performance of the load bearing wall system apartments to meet the regulation of the Ministry of Construction and Transportation (MOCT). To increase the heavy-weight impact noise isolation performance, improvement in structural systems such as increasing concrete slab thickness and application of rahmen structure were proposed. In this study floor impact sound levels from toil apartments with two rahmen structure multi-story residential buildings were measured before the construction of the buildings finished. Measurements were made at living room and two bedrooms at each apartment when the finishing processes were finished. The average value of light-weight impact sound level from ten apartments was 56dB (L'$\sub$n,Aw/). The heavy-weight impact sound level was 44dB (L'$\sub$i.Fmax.Aw/) and the impact sound level of the impact ball was 41dB(L'$\sub$i.Fmax.Aw/), As a result floor impact noises at the rahmen structure system were lower than the regulation level.

• 전기학회논문지
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• 제65권6호
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• pp.1103-1107
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• 2016

The automatic tensioning device of the catenary system constantly maintains the tension of the trolley wire by absorbing the variations due to the elasticity of the line caused by temperature variation. The tension plays an important role in affecting the electric motorcar operation directly. This paper suggests the methodology of the life cycle extension and the maintenance of the automatic tensioning device by means of performance diagnosis of the pulley type automatic tensioning device which has been commonly used for the electric railway system. Through conducting performance diagnosis and comparative test for the wornout pulley type automatic tensioning device by replacing the components such as the bearing and the bearing shaft without replacing all the assembly, the tensioning device is analyzed whether it is properly functioned. Provided that the maintenance regulation is reinforced so as to implement the bearing replacement through periodical precise inspection along with random check-up inspection which is now carried out by the operating organizations, it is ensured that the life cycle extension and the reduction of maintenance cost of the tensioning device could be achieved.