• Asian Pacific Journal of Cancer Prevention
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• v.17 no.6
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• pp.2895-2899
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• 2016

Background: Increasing breast cancer (BC) incidence rates have been reported from India; causal factors for this increased incidence are not understood and diagnosis is mostly in advanced stages. Trivandrum exhibits the highest BC incidence rates in India. This study aimed to estimate trends in incidence by age from 2005-2014, to predict rates through 2020 and to assess the stage at diagnosis of BC in Trivandrum. Materials and Methods: BC cases were obtained from the Population Based Cancer Registry, Trivandrum. Distribution of stage at diagnosis and incidence rates of BC [Age-specific (ASpR), crude (CR) and age-standardized (ASR)] are described and employed with a joinpoint regression model to estimate average annual percent changes (AAPC) and a Bayesian model to estimate predictive rates. Results: BC accounts for 31% (2681/8737) of all female cancers in Trivandrum. Thirty-five percent (944/2681) are <50 years of age and only 9% present with stage I disease. Average age increased from 53 to 56.4 years (p=0.0001), CR (per $10^5$ women) increased from 39 (ASR: 35.2) to 55.4 (ASR: 43.4), AAPC for CR was 5.0 (p=0.001) and ASR was 3.1 (p=0.001). Rates increased from 50 years. Predicted ASpR is 174 in 50-59 years, 231 in > 60 years and overall CR is 80 (ASR: 57) for 2019-20. Conclusions: BC, mostly diagnosed in advanced stages, is rising rapidly in South India with large increases likely in the future; particularly among post-menopausal women. This increase might be due to aging and/or changes in lifestyle factors. Reasons for the increased incidence and late stage diagnosis need to be studied.

• Journal of Climate Change Research
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• v.2 no.4
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• pp.269-281
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• 2011

In this review, numerical model results from global and regional climate models are introduced to regional detailed climate changes over East Asia and Korea. In particular, regional climate change scenarios in this region, which are created by several research groups in Korea based on Special Report on Emissions Scenarios (SRES) of IPCC 4th assessment report are introduced and characteristics of the scenarios are investigated. Despite slight differences in intensity, all scenarios reveal prominent warming over the Korean peninsula in future climate. Changes in precipitation amount vary with given scenarios and periods, but the frequency and intensity of heavy precipitation generally tend to increase in all scenarios. South Korea except for mountainous regions is expected to change into subtropical climate in future, which accompanies distinct changes in ecosystems and seasons.

• Journal of Sasang Constitutional Medicine
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• v.18 no.2
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• pp.125-132
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• 2006

1. Objectives The purpose of this study was to examine the regional cerebral blood-flow(r-CBF) difference between OMT(Oriental Music Therapy) group and control group using brain SPECT, to evaluate the effect of OMT in ischemic stroke patients Classified by Sasang Constitutional. 2. Methods We selected 10 ischemic storke patients, classified groups into OMT group or control group. r-CBF of two groups were examined by brain SPECT. in all group we applied SCM(Sasang constitutional medicine)treatment for 4-5 weaks, and additionally in OMT group We applied OMT for 4-5 weaks. after that all the r-CBF of two groups took brain SPECT again. r-CBF difference and change before and after SCM treatment and OMT were quantified and analyzed using SPM. 3. Results r-CBF of OMT groups were increased compared to control groups. 4. Conclusions This study demonstrated that Sasang Constitutional OMT increased regional cerebral blood perfusion to the corresponding brain areas in ischemic stroke patients.

• The Korea Journal of Herbology
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• v.31 no.2
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• pp.13-19
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• 2016

Objectives : The present study was designed to evaluate the protective effect of Allium tuberosum (AT) extract on atherosclerosis in LDL receptor knockout (LDLr KO) mouse fed western diet.Methods : The AT was extracted 70% ethanol. The experimental groups were divided with four groups of LDLr KO mice, one group fed a normal diet and the others fed a Western diets for 8weeks. Two Western diet groups were orally administered AT extract at dosage of 100 and 300 mg/kg body weight. The body weight and food intake were measured every day. We measured levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and Glucose in serum. Also, effect of AT extract performed using H&E staining.Results : The AT treatment groups showed decrease in body weight and food efficiency in comparison with control group. Blood biochemistry parameters such as TG, TC, LDL, and glucose levels were increased in control group, while AT treatment groups were reduced. Also, the increased levels of ALT and AST were improved by AT extract. We confirmed that the weights of liver, kidney, subcutaneous fat, epididymal fat, kidney leaf fat, and intraabdominal fat were change in LDLr KO mice treated AT extract. In addition, histopathological changes in liver and aorta were similar to normal group.Conclusions : Based on these results, the AT extract is considered to make prevention of atherosclerosis through reduction and functional improvement of the liver and vascular endothelial cells in the body fat accumulation and lipid content in LDLr ko mouse model.

• The Korea Journal of Herbology
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• v.31 no.1
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• pp.17-23
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• 2016

Objectives : This study was designed to protect effect on atherosclerosis through regulation of low density lipoprotein(LDL) by 70 % ethanol extract Ganoderma lucidum (GL) in LDL receptor knockout mouse (LDLr ko mice) fed Western diet.Methods : The LDLr ko mice were divided into 3 groups ; Control, GL100, and GL300. After grouping, LDLr ko mice were fed Western diet. The GL (100 or 300 mg/kg body weight/day, p.o.) was administered every day for 8 weeks. The body weight and food intake were measured every day. The changes in the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine, triglyceride (TG), total cholesterol (TC), and high-density lipoprotein (HDL) in serum were analyzed after experiment.Results : The LDLr ko mice fed Western diet were increased body weight gain and blood biochemistry parameters such as ALT, AST, TG, TC, and LDL. However GL300 group significantly reduced the body weight. Also TG, TC, and LDL level did not increase. The levels of ALT, AST, HDL were not changed. Also, LDLr ko mice model liver were observed lipid drop, but GL groups did not appear. Futhermore, histological analysis of GL groups aorta tissue were similar to NOR groups.Conclusions : We confirmed that whether GL administration is protect atherosclerosis or not. As the results, blood biochemistry and histological analysis did not changed much in GL administration groups. This study provides scientific evidence that GL protect the atherosclerosis through the reduction of LDL cholesterol. Therefore GL has potential medicine inhibition of atherosclerosis.

• Wind and Structures
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• v.2 no.3
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• pp.133-150
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• 1999

Significant costs to the public and private sectors due to recent extreme wind events have motivated the need for systematic post-hurricane damage data collection and analysis. Current post disaster data are collected by many different interested groups such as government agencies, voluntary disaster relief agencies, representatives of media companies, academicians and companies in the private sector. Each group has an interest in a particular type of data. However, members of each group collect data using different techniques. This disparity in data is not conducive to quantifying damage data and, therefore, inhibits the statistical and spatial description of damage and comparisons of damage among different extreme wind events. The data collection does not allow comparisons of data or results of analyses within a group and also prohibits comparison of damage data and information among different groups. Typically, analyses of data from a given event lead to different conclusion depending upon the definition of damage used by individual investigators and the type of data collected making it difficult for members of groups to compare the results of their analyses with a common language and basis. A formal method of data collection and analysis-within any single group-would allow comparisons to be made among different individuals, hazardous events and eventually among different groups, thus facilitating the management and reduction of damage due to future disaster. This research introduces a definition of damage to single family dwellings, and a common method of data collection and analysis suited for groups interested in regional characterization of damage. The current state-of-data is presented and a method for data collection is recommended based on these existing data collection methods. A fixed-scale damage index is proposed to consider the damage to a dwelling's feature. Finally, the damage index is applied to three dwellings damaged by Hurricane Iniki (1992). The damage index reflects the reduced functionality of a structure as a single family detached dwelling and provides a means to evaluate regional damage due to a single event or to compare damage due to events of different severity. Evaluation of the damage index and the data available support recommendation for future data collection efforts.

• Journal of the Korean association of regional geographers
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• v.22 no.4
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• pp.774-791
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• 2016

Recent studies on Asian suburbanization suggest that their settlement patterns do not confirm to those of earlier migrant streams, and that different residential patterns of Asian ethnic minority groups have created a complex ethnic mosaic in suburban areas. This paper examines the extent to which residential patterns of main Asian minority groups have changed in Westchester, where is one of suburban counties around New York City. With mapping base on Census of Population data in 2000 and 2010 years, the residential patterns of five Asian groups (Asian Indians, Chinese, Filipinos, Japanese, and Koreans) are analyzed through the indices of segregation. The residential segregation geography of the Asian ethnic groups is characterized by dispersed concentration. There is a difference among the characteristics of the ethnic neighborhoods in which Asian minority groups are residentially concentrated.

• SUVANNABHUMI
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• v.11 no.1
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• pp.101-132
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• 2019

Why do some local rebel groups choose to form asymmetric alliances with large transnational terrorist organizations? This paper examines asymmetric terrorist alliance patterns by studying the international ties of domestic insurgencies in Southeast Asia. It uses data from Indonesia, Malaysia, the Philippines, and Thailand to construct a theory defining the determinants of the choice of alliance strategies by terrorist groups. The findings conclude that rebels with limited aims prefer to act alone out of fear of entrapment. They are cautious of becoming associated with the struggle of transnational radical groups and provoking organized response from international and regional counterterrorism authorities. Local groups are more likely to seek alliance with an established movement when they have ambitious final objectives, challenging the core interests of the target state. In this case, the benefits of training and logistic support provided by an experienced organization outweigh the costs of becoming a target for coordinated counterterrorist campaign.

• International Journal of Highway Engineering
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• v.19 no.3
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• pp.83-90
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• 2017

PURPOSES : In this study, systematic road snow-removal capabilities were estimated based on previous historical data for road-snowremoval works. The final results can be used to aid decision-making strategies for cost-effective snow-removal works by regional offices. METHODS : First, road snow-removal historical data from the road snow-removal management system (RSMS), operated by the Ministry of Land, Infrastructure and Transport, were employed to determine specific characteristics of the snow-removal capabilities by region. The actual owned amount and actual used amount of infrastructure were analyzed for the past three years. Second, the regional offices were classified using K-means clustering into groups "close" to one another. Actual used snow-removal infrastructure was determined from the number of snow-removal working days. Finally, the correlation between the de-icing materials used and infrastructure was analyzed. Significant differences were found among the amounts of used infrastructure depending on snowfall intensity for each regional office during the past three years. RESULTS:The results showed that the amount of snow-removal infrastructure used for low heavy-snowfall intensity did not appear to depend on the amount of heavy snowfall, and therefore, high variation is observed in each area. CONCLUSIONS:This implies that the final analysis results will be useful when making decisions on snow-removal works.

• Journal of Ecology and Environment
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• v.38 no.1
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• pp.1-14
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• 2015

Whilst it is clear that increasing temperatures from global environmental change will impact the positions of alpine treelines, it is likely that a range of regional and local scaled factors will mediate the overall impact of global scale climate drivers. We summarized 12 categories of abiotic and biotic factors as 4 groups determining treeline positions. First, there are global factors related to climate-induced growth limitation and carbon limitation. Second, there are seven regional and local factors related to treeline dynamics including frost stress, topography, water stress, snow, wind, fire and non-fire disturbance. Third, species-specific factors can control treeline dynamics through their influence on reproduction and life history traits. Fourth, there are positive feedbacks in structuring the dynamics of treelines. Globally, the commonly accepted growth limitation hypothesis is that growth at a treeline is limited by temperature. Meanwhile, positive feedbacks between canopy cover and tree establishment are likely to control the spatial pattern and temporal dynamics of many treelines. The presence of non-linear dynamics at treelines has implications for the use of treelines as barometers of climate change because the lagged responses and abrupt shifts inherent in non-equilibrium systems may combine to mask the overall climate trend.