• Health Policy and Management
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• v.31 no.1
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• pp.114-124
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• 2021

Background: In this study, we aimed to investigate the interaction effects of individual socioeconomic status and regional deprivation on the onset of diabetes complications and diabetes-related hospitalization among type 2 diabetes patients. Methods: Korean National Health Insurance Service National Sample Cohort data from 2002 to 2013 were used. A total of 50,954 patients newly diagnosed with type 2 diabetes from 2004 to 2012 and aged 30 years or above were included. We classified patients into six groups according to individual income level and neighborhood deprivation: 'high in advantaged,' 'high in disadvantaged,' 'middle in advantaged,' 'middle in disadvantaged,' 'low in advantaged,' and 'low in disadvantaged.' We calculated hazard ratios (HR) of onset of diabetes complication and diabetes-related hospitalization using the Cox proportional hazard model, with the reference group as diabetes patients with high income in advantaged regions. Results: In terms of the interaction effects of individual income level and regional socioeconomic level, even with the same low individual income level, the group with a high regional socioeconomic level (low in advantaged) showed low HRs for the onset of diabetes complication (HR, 1.04; 95% confidence interval [CI], 1.00-1.08) compared to the 'low in disadvantaged' group (HR, 1.10; 95% CI, 1.05-1.16). In addition, the 'high in advantaged' group showed slightly higher HRs for the onset of diabetes complication (HR, 1.06; 95% CI, 1.00-1.11) compared to the 'low in advantaged' and it appeared to be associated with slight mitigation of the risk of diabetes complication. For the low-income level, the patients in disadvantaged regions showed the highest HRs for diabetes-related hospitalization (HR, 1.29; 95% CI, 1.19-1.41) compared to the other groups. Conclusion: Although we need to perform further investigations to reveal the mechanisms that led to our results, interaction effects individual socioeconomic status and regional deprivation might be associated with on onset of diabetes complications and diabetes-related hospitalization among type 2 diabetes patients.

• STI Policy Review
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• v.9 no.1
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• pp.77-98
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• 2018

In the past few decades, the importance of dynamics of University-Industry Linkage(UIL) in strengthening national and regional innovation competency and global competitiveness has been progressively more acknowledged. However, establishing an effective UIL for a better economic development is still a challenging endeavor in Ethiopia, particularly in Tigray region. This study is aimed at assessing the status of UIL and in order to achieve such aim it analyzed the determinants of firms' intensity of interaction with the Mekelle University (MU) and the effect of the intensity of interaction on the relevant firms' innovation performance. The findings of the study showed that the status of UIL between the firms and the university in Tigray region was at an infant stage. The study also found that firm size, firm age (startups) and government supports have had a significant effect on firms' intensity of interaction with the MU. However, the firms' intensity of interaction with the MU did not have any significant effect on the firms' innovation performance. In contrast, cooperation with customers, other groups and suppliers, firm size, firm age, and in-house R&D activities were found to have a significant effect on the firms' innovation performance. In conclusion, the acquisition of knowledge and technology from university does not have an important role in firms' innovation performance in the studied region. Consequently, the government should design effective strategies and assign responsible bodies to implement the strategies, create awareness, and organize both firms and university to meet and work together in order to enhance firms' innovation performance.

• Journal of Korean Society of Rural Planning
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• v.16 no.4
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• pp.61-75
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• 2010

Daily living area can be delimited differently depending on what area is to be focused. Based on regional interaction, the present study empirically analyzed the difference between living areas focusing on rural area and ones relying on urban area. We established two types of living areas in Busan-Ulsan mega city with different focus areas (rural versus urban), using travel OD data (2006). According to the result, the fonn of spatial clusters in urban living area differed from that of spatial clusters in rural area; the boundaries of living area were not fit to those of administrative areas in both types; and living areas in both types tended to extend over more than two administrative areas. The results cast some implications concerning spatial planning and policy for living area delimitation. First, since the spatial structure and interconnection of urban area differs to those of rural area, it is required to delimit living areas discriminatively depending on the objectives of the spatial plan. Additionally, the living area should be established more specifically and systematically by further subdividing the form of spaces depending on the objectives and types of the plan. Second, the administrative areas should be consolidated now that the difference of boundaries of administrative and living areas lead to inconvenience of residents, increased administration costs and scale diseconomy. Lastly, the living areas should be delimited by the metropolitan or mega city planning and thus be reflected to its offsprings.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10691-10695
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• 2015

Background: Association of angiotensin converting enzyme (ACE) gene polymorphisms with lung cancer susceptibility remains uncertain and varies with ethnicity. Northeast India represents a geographically, culturally, and ethnically isolated population. The area reports an especially high rate of tobacco usage in a variety of ways of consumption, compared with the rest of the Indian population. Materials and Methods: We conducted a population based case control study in two major high risk region for lung cancer from Northeast India. A total of 151 consecutive lung cancer cases diagnosed histopathologically and equal numbers of controls were recruited with record of relevant sociodemographic information. Blood samples were collected and processed to identify ACE gene polymorphism. Results: Significantly higher (40.4 % vs 29.1%, OR=1.97, CI=1.04-3.72; p=0.037) prevalence of the ACE II genotype was observed among lung cancer cases. Smoking was significantly associated with increased risk of lung cancer (OR=1.70, CI=1.02-2.81; p=0.041). An enhanced risk was also observed for interaction of ACE II genotype with tobacco smoking (OR=4.09, CI=1.51-11.05; p=0.005) and chewing (OR=3.68, CI=1.22-11.13; p=0.021). Conclusions: The present study indicates significant association s of the ACE II genotype with lung cancer in high risk Northeast India.

• Journal of Food Hygiene and Safety
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• v.32 no.2
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• pp.89-95
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• 2017

A rapid, sensitive analytical method for glucuronolactone in beverages was developed and validated using hydrophilic interaction liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HILIC-ESI-MS/MS). To determine the optimum analytical conditions for glucuronolactone, three different kinds of HILIC columns and two mobile phases with different pH values were examined. An amide-bonded stationary phase with a pH 9 acetonitrile-rich mobile phase was the best condition in terms of column retention, ESI-MS/MS response area, and signal-to-noise ratio. After extraction, glucuronolactone was separated through the HILIC amide column and detected by negative ESI-MS/MS in selected reaction monitoring (SRM) mode. Nine energy drinks sold in Korea were spiked with glucuronolactone at a concentration of 5 ng/mL; the Monster $Energy^{TM}$ sample showed the smallest peak area and its signal-to-noise ratio was used for method validation. Good linearity was obtained in the concentration range from 20 to 1500 ng/mL with a correlation coefficient > 0.998. The developed method had a limit of detection (LOD) of 6 ng/mL and a limit of quantitation (LOQ) of 20 ng/mL. The recovery of this method at concentration of 20, 100, 500, and 1000 ng/mL was 96.3%-99.2% with relative standard deviations (RSD) of 1.6%-14.0%. A reproducibility precision assessment at concentration of 100 and 500 ng/mL was carried out among three laboratories. The recovery of that evaluation was 95.1%-102.3% with RSD of 2.7%-7.0%. An analysis of variance indicated that there was no difference between the recovery results of the three laboratories at the 5% significance level. The validated method is applicable to inspecting beverages adulterated with glucuronolactone in Korea.

• The Journal of the Korea Contents Association
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• v.5 no.3
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• pp.141-150
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• 2005

This study analyzed the regional current status of city J which has growth potentials of regional information, its necessity and the characteristic of the regional information for this area. The development plans of contents on the regional information based on the construction of the information infrastructure, are proposed to the important fields such as the fields of administration, industry and life information. We have also studied such as the development contents, process, providing of service, evaluation, interaction among the contents, demanders of service and providers of service related to their contents. Therefore proposal to the development plans of contents for the regional information, is able to be brought into much spread of regional information and will contribute to the development of regional information as well as get more competitive regional power.

• Journal of Korean Society of Rural Planning
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• v.14 no.2
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• pp.13-23
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• 2008

In this paper, we estimated the economic impacts of Korea-EU FTA on the agricultural sector in GyeongGi-Do. In particular, we estimated the economic impacts of agricultural production decrease resulting from Korea-EU FTA for 31 sub-regions in GyeongGi-Do by 15 industrial sectors. We employ a regional economic impact model combining a regional input-output model with a spatial allocation model. We found that the size of inter-industrial impacts are quite different across regions. Our results suggest the importance of agricultural and industrial policy considering the impacts of industrial sectors at the regional level.

• Journal of Korean Society of Rural Planning
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• v.14 no.3
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• pp.63-73
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• 2008

The purpose of this study is to analyze the determinants of the digital divide at individual level and regional level in Korea, considering interaction between individual and the regional variables. Following results are obtained. First, individual level digital devide in the 16 different regions has been found in terms of Internet use, implying the needs for further analysis on impact of the regional factor in individual Internet use. Second, the result finds the impact of level-l individual variables, "gender, age, education, income and jobs" on digital divide, significantly at level 10% level. Third, the regional variables influencing the individual digital divide were not found at state level. However, regional factors might affect digital devide at county level. Study suggest some plans to reduce digital divide. First, the digital devide at individual level should be remedied by focusing on neglected class of people. Second, we need to approach the digital divide by analyzing in more detail, reflecting interactions of the regional variables and individual variables. Third, we should come up with a policy for mending the digital divide at regional level.

• Korean Journal of Organic Agriculture
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• v.27 no.3
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• pp.307-325
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• 2019

This study aims to analyze the regional variations in which appear during the formation process of educational community in rural villages from the perspective of regional innovation theory. The study results revealed that the activities to form an educational community of the Songak village significantly influenced the variations across the social, economic and environmental aspects beyond an innovation of public education within the region based on interrelation between schools and villages. In other words, the activities including interactions and group learnings have been actively promoted among the various relevant stakeholders, thereby resulting in a variety of positive variations such as expanded regional welfare base, activated voluntary residents community gatherings based on the unity and cooperation, broadened socioeconomic opportunities, satisfaction on educational and cultural desires, and construction of healthy ecological environment in the region. Therefore, it is thought that regional development policy suitable for each region needs to be established by embracing the fact that activities to form a village educational community entail significant implication and value as the comprehensive regional innovation activities across the entire domains in each region.

• Journal of Korean Society of Rural Planning
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• v.12 no.4 s.33
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• pp.99-114
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• 2006

Under awareness of the importance of interaction between local research agencies and farmers in developing local agriculture, this study attempts to analyse the level of interaction in extension services of Experiment Station. The data were collected through the interview with researchers in five Experiment Stations and farmers who have made contact with the researchers. The results of the analysis are as follow: (1) The Experiment Stations are currently providing extension services though they are originally research-oriented agencies. The extension methods of Experiment Stations are similar with those of extension agencies. (2) The more systematic the characteristic of extension service type is, the higher level of interaction is generated with several exceptions which should not be ignored. This study accentuates the efforts to improve the level of interaction as well as to construct a system as a linked set of actors.