• Reproductive and Developmental Biology
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• 제36권3호
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• pp.207-212
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• 2012

The shortage of human organs for transplantation has induced the research on the possibility of using animal as porcine. However, pig to human transplantation as known as xeno-transplantation has major problem as immunorejection. Recently, the solutions of pig to human xenotransplantation are commonly mentioned as having a genetically modification which include alpha 1, 3 galatosyl transferase knockout (GTKO) and immune-suppressing gene transgenic model. Unfortunately, the expression level of transgenic gene is very low activity. Therefore, development of gene overexpression system is the most urgent issue. Also, the tissue specific overexpression system is very important. Because most blood vessels are endothelial cells, establishment of the endothelial-specific promoter is attractive candidates for the introduction of suppressing immunorejection. In this study, we focus the ICAM2 promoter which has endothelial-specific regulatory region. To detect the regulatory region of ICAM2 promoter, we cloned 3.7 kb size mini-pig ICAM2 promoter. We conduct serial deletion of 5' flanking region of mini-pig ICAM2 promoter then selected promoter size as 1 kb, 1.5 kb, 2 kb, 2.5 kb, and 3 kb. To analyze promoter activity, luciferase assay system was conducted among these vectors and compare endothelial activity with epithelial cells. The reporter gene assay revealed that ICAM2 promoter has critical activity in endothelial cells (CPAE) and 1 kb size of ICAM2 promoter activity was significantly increased. Taken together, our studies suggest that mini-pig ICMA2 promoter is endothelial cell specific overexpression promoter and among above all size of promoters, 1 kb size promoter is optimal candidate to overcome the vascular immunorejection in pig to human xenotransplantation.

• 전기학회논문지
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• 제64권9호
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• pp.1391-1397
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• 2015

Recently, various researches are conducted in the application of regenerative energy produced during the operation of an electric locomotive. Regenerative energy is produced by a generator in the brake procedure. The generator is operated by kinetic energy of an electric railroad using an electric motor. The process of producing regenerative energy varies with the current type of a railroad and its running condition. The quality of electric power can be improved and electric energy can be utilized effectively, especially in the use of an energy storage system (ESS). Thus, it is necessary to apply ESS into AC section and high speed railway. This study analyses the composition of the regenerative ESS equipment installed in Yong-Jeong sectioning post, operational principle, charge and discharge algorithm and energy efficiency. The analysis shows that CO2 emissions can be reduced about 0.5 ton per a day. In addition, ESS helps saving the energy and the compensation of the voltage drop caused by the operation of high speed train when it is installed at the end of the feeder section. The number of high speed train will be increased continuously related to the electrification rate. Therefore, applying the ESS to high speed railway is expected to solve the instability of the feeder voltage and the equipment capacity problem caused by the high speed trains.

• 한국연소학회지
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• 제8권1호
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• pp.17-24
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• 2003

The conventional regenerative system has a high thermal efficiency as well as energy saving using the high preheated combustion air. in spite of these advantages, it can not avoid high nitric oxide emissions. Recently, flameless combustion has received much attention to solve these problems. In this research, numerical analysis is performed for flow-combustion phenomena in the self regenerative burner. In this analysis we used Fluent 6.0 code. the that is developed for commercial use, Methane gas is used as a fuel and two-step reaction model for methane and Zeldovich mechanism for NO generation are used. the velocity of the preheated combustion air is used as a parameter and we analyze the characteristics of flow-field, temperature distributions and NO emissions. Due to the increased recirculation rate, the maximum temperature of flame is significantly increased and NOx emissions is reduced.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2002년도 제25회 KOSCI SYMPOSIUM 논문집
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• pp.97-104
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• 2002

The conventional regenerative system has a high thermal efficiency as well as energy saving using the high preheated combustion air. in spite of these advantages, it can not avoid high nitric oxide emissions. Recently, flameless combustion has received much attention to solve these problems. In this research, numerical analysis is performed for flow-combustion phenomena in the self regenerative burner. In this analysis we used Fluent 6.0 code. the that is developed for commercial use, Methane gas is used as a fuel and two-step reaction model for methane and Zeldovich mechanism for NO generation are used. the velocity of the preheated combustion air is used as a parameter and we analyze the characteristics of flow-field, temperature distributions and NO emissions. Due to the increased recirculation rate, the maximum temperature of flame is significantly increased and NOx emissions is reduced

• 대한치과의사협회지
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• 제51권10호
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• pp.542-550
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• 2013

The immature teeth with apical periodontitis present considerable challenges to clinicians. Therefore, new treatment protocols have been suggested to overcome the problems encountered in traditional methods. Regenerative treatment (revascularization) is one of such methods. Many case reports on the revascularization of infected immature teeth have been published, and in most of them, immature teeth with even a periapical abscess continued root formation after the disinfection of the root canal system. We now believe that this continued root formation is not an exceptional incident. As a result, it appeared that apexification has been giving way to a revascularization technique, which is a new option, in treating necrotic immature teeth. These new methods appear to be based on the healing potential of stem cells. The potential of healing or regeneration of stem cells, which are located around teeth, seems to be greater than we thought before. This review summarizes the current techniques for considering regenerative endodontic treatment procedures in treating the immature permanent tooth with pulp necrosis.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.1039-1040
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• 2007

This paper is derived a solutions for an analytical model of an induction motor and the formula of regenerative power, based on spiral vector. The torque is controlled linearity through variations of the slip angular velocity, based on the field acceleration method (FAM). And also PWM inverter fed induction motor drives is schemed to be easily a regenerative power. The experimental tests verify the performance of the FAM, proving that good behavior of the drive is achieved in the transient and steady state operating condition. and are discussed to shave the power that regenerative power is measured at the operating acceleration or deceleration of servo system.

• Journal of Power Electronics
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• 제17권4호
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• pp.1071-1087
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• 2017

This paper introduces a DC/AC converter, which can be connected in parallel with a diode rectifier for regenerative applications. The DC/AC converter is supposed to transmit regenerative energy to the power grid when a motor is braking. Isolation transformers are not needed in the topology, which can reduce the size and cost. An analysis of the zero-order current existing in the system is carried out. In addition, algorithms to minimize the zero-order current, control the power factor and keep the DC bus voltage stable are discussed. A 55kW industrial prototype is built to verify the proposed analysis and control strategies.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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• pp.3117-3123
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• 2011

도시철도의 전동차는 변전설비로부터 전력을 공급받아 지상, 지하부의 다양한 선로조건(구배)를 지닌 선로를 운행하며, 열차 제동 시 많은 회생전력이 발생하고 있다. 회생제동은 에너지를 재활용 할 뿐만 아니라 기계식 브레이크의 사용을 줄이는 매우 이상적인 시스템이라고 할 수 있다. 또한 중요한 점은 회생제동이 가능한 시스템은 발생된 에너지가 어떤 정해진 흐름을 가지고 소모되고 재활용 가능하다는 것이다. 본 연구에서는 서울도시철도 전력공급소(변전소)의 전동차용 전력의 정밀분석을 실시하였다. 이를 통하여 변전소 전력공급과 전동차 전력사용의 데이터 분석을 통하여 회생전력 활용 연구의 기반작업을 수행하였다.

• 한국유체기계학회 논문집
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• 제16권5호
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• pp.24-28
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• 2013

Visualization of internal flow of a regenerative blower has been made by injecting a tracer directly into the flow. For the convenience of visualization, working fluid has been replaced by water and marbling color oil has been used as a tracer. Oil droplet has been injected near the inlet of the blower and the streak has been recorded using a high speed camera with the illumination of high power light sources. At first, droplets have irregular motion in the near inlet area and enter into a groove of the impeller. Then the droplets circulate inside the groove while translated by the rotational motion of the impeller. When the droplets get out of the impeller groove, their speed is lower than that of impeller. And the droplets repeatedly enter into the groove and circulate inside the grooves. Then the droplets either flow to the outlet or reenter into the inlet area through stripper. Through this experimental study, internally circulating motion of the flow inside a regenerative blower has been characterized.

• 에너지공학
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• 제18권2호
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• pp.93-100
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• 2009

습식압축으로 압축소요동력을 줄이고 재생기로 배기가스 에너지를 회수함으로써 열효율을 향상시킬 수 있는 습식압축 재생 브레이튼 사이클에 대하여 엑서지 해석을 수행하였다. 해석모델을 통하여 시스템의 엑서지 효율과 요소별 엑서지 파괴비 및 배기가스로 인한 엑서지 손실비에 미치는 압력비와 물분사율의 영향을 조사하였다. 전형적인 운전조건에 대한 계산 결과 습식압축 재생 가스터빈 사이클에 의하여 엑서지 효율을 상당히 향상시킬 수 있음을 확인하였다. 물 분사 효과는 배기가스의 엑서지 손실의 감소와 출력 동력의 증가로 나타난다.